• Title/Summary/Keyword: IL-2 수용기

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Effects of Water Soluble Potassium Silicate by Soil Drenching Application on Watermelon (Citrullus lanatus var. lanatus) (시설수박에 대한 수용성 규산칼륨 토양관주 효과)

  • Kim, Young-Sang;Kang, Hyo-Jung;Kim, Tae-Il;Jeong, Taek-Gu;Han, Jong-Woo;Kim, Ik-Jei;Nam, Sang-Young;Kim, Ki-In
    • Journal of Bio-Environment Control
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    • v.24 no.3
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    • pp.235-242
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    • 2015
  • The objective of this study was to determine the effects of soluble potassium silicate by soil drenching application on watermelon growth, yield, and nutrient uptake. The potassium silicate rates were control (No potassium silicate), 1.63mM, 3.25mM, 6.50mM. The potassium silicate were treated 6 times (twice before fruit forming and 4 times after fruit forming per 7 day. Soil chemical properties, such as soil pH, EC, available phosphorus and silicate, exchangeable K, nitrate-N levels were increased after potassium silicate treatment, while the concentrations of soil organic matter, exchangeable Ca and Mg were similar to control. The growth characteristics of watermelon, such as stem diameter, fresh and dry weight of watermelon at harvest were thicker and heavier for increased potassium silicate treatment than the control, while number of node, and plant length were same for all treatments. With increased potassium silicate treatment, nutrient concentrations, such as P and K in the watermelon leaf at harvest were increased, N concentration in the leaf was decreased, and Ca and Mg concentrations in the leaf were same. Chlorophyll content was increased with increased potassium silicate application. The occurrence of powdery mildew was lower for the potassium silicate treatments than the control. Fresh watermelon weight for the potassium silicate treatments was 0.1 to 0.5kg per watermelon heavier than the control, sugar content was 0.5 to $0.6^{\circ}Brix$ higher than control, and merchantable watermelon was 2 to 4% increased compared to the control. These results suggest that potassium silicate application by soil drenching method in the greenhouse can improve watermelon nutrient uptake, merchantable watermelon and suppress the occurrence of powdery mildew.

Design and fabrication of a RFID Reader Antenna in 900MHz Band (900MHz 대역 RFID 리더기 안테나 설계 및 제작)

  • Kim, Chan-Baek;Park, Seong-Il;Ko, Young-Hyuk
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.05a
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    • pp.125-128
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    • 2008
  • In this paper, a stand-type planar antenna of 900MHz RFID band is designed and fabricated. As the proposed antenna is stand-type use of air permittivity, Bandwidth used ground height at rectangle patch structure and coaxial feed line is widen. Also wideband width can solve problem that RFID tag attached to things happens frequency shift keying phenomenon by liquid, special metal, temperature, humidity etc. Bandwidth of fabricated antenna to VSWR less than 2 is satisfied 11.9% at $890MHz{\sim}1000MHz$. And proposed antenna is circular polarization antenna of operating characteristics that axial ratio is less than 2 and gain is 6dBi.

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Measures to Secure Safety according to Gas pipe Hydrogen Mixing(Carbon Neutral) (가스배관 수소혼입(탄소중립)에 따른 안전확보 방안)

  • Kwak, Che-Sik;Sin, Dong-Il
    • Proceedings of the Korean Society of Disaster Information Conference
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    • 2022.10a
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    • pp.290-291
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    • 2022
  • 본 논문에서는 우리나라 2030년 국가 온실가스 감축목표(NDC*, 291백만톤 감축)달성 및 2050년 탄소중립 목표 달성을 위해 필연적으로 수반되는 천연가스 내 수소 혼입에 따른 안전성확보 방안과 수소혼입에 따른 국민 불안감 해소 및 수용성 제고를 위한 대안을 제시하고, 해외 사례를 연구 하였다. 탄소중립은 온실가스(이산화탄소 등)의 배출량을 최대한 줄이고, 남은 온실가스를 흡수, 제거해서 실질적인 배출량이 "0"이 되는 것을 의미하고, 수소혼입은 도시가스의 주성분인 메탄 연소시 발생하는 CO2를 최소화하기 위해 수소(H2)를 도시가스에 일정비율 혼합하는 것을 말한다. 본 연구에서는 수소 혼입 시 우려되는 수소취성 및 배관내구성 문제와 수소 특성인 작은 입자로 인한 누출 위험성, 고층에서 메탄과 수소가 분리되는 현상 등에 따른 문제를 도출하고 이에 대한 안전관리 방안도 함께 제시하였다. 또한, 도시가스 배관에 수소 혼입시 천연가스 대체를 통한 온실가스 감축 및 기존 배관망 사용을 통한 경제성 분석결과와 국가 온실가스 감축에 어느 정도 기영할 수 있는지도 함께 기술하였다.

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Anti-inflammatory Effect of Boswellia sacra (Franckincense) Essential Oil in a Mouse Model of Allergic Asthma (알러지성 천식 모델 생쥐에서 프랑킨센스 에센셜 오일의 염증 억제 효과)

  • Lee, Hye-Youn;Yun, Mi-Young;Kang, Sang-Mo
    • Microbiology and Biotechnology Letters
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    • v.36 no.4
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    • pp.343-352
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    • 2008
  • Frankincense, the gum resin derived from Boswellia species, is complex mixtures composed of about $5{\sim}9%$ highly aromatic essential oil, $65{\sim}85%$ alcohol-soluble resins, and the remaining water-soluble gums. The anti-inflammatory properties of frankincense, alcohole-soluble resins, are well-recognized, but the question of whether aromatic essential oil also plays a role in the allergic asthma remains unanswered. This study was performed to evaluate anti-inflammatory effects of Boswellia sacra essential oil (BSEO) on ovalbumin (OVA)-induced asthma mouse model. BALB/c mice after intraperitoneal OVA sensitization were challenged with intratracheal OVA. One experimental group was inhaled with 0.3% BSEO for the later 8 weeks. BALB/c mice were sensitized and challenged with OVA and developed airway eosinophilia, mucus hypersecretion, and airway hyperresponsiveness. In contrast, the BSEO treated mice had reduced a number of eosinophils among BALF cells, goblet cell hyperplasia, and airway hyperresponsiveness. Cytokine analysis of BALF revealed that BSEO caused an increase in Th1 cytokine (interferon-$\gamma$ (IFN-$\gamma$)) and a decrease in Th2 cytokines (interleukin-4 (IL-4), IL-5 and IL-13) levels. In addition, the OVA-specific serum IgE and eotaxin levels were also reduced. In mice inhaled BSEO, $CD4^+$, $CD3^+/CCR3^+$, and $B220^+/CD23^+$ mediastinal lymph nodes cells were also decreased. These results suggest that inhaled BSEO as a immunomodulator in Th1/Th2 mediated asthma may have therapeutic potential for the treatment in allergic airway inflammation by a simple, cost-effective way.

DESIGN AND FABRICATION OF S-BAND DIPLEXER FOR LEO TT&C APPLICATION (저궤도 위성 관제용 S-대역 다이플렉서 설계 및 제작)

  • Ahn, Sang-Il;Park, Dong-Chul
    • Journal of Astronomy and Space Sciences
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    • v.24 no.4
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    • pp.397-408
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    • 2007
  • Diplexer is one of core devices needed to communicate with satellite using single ground antenna by separating uplink and downlink signal. This paper presents the design of the S-band diplexer for LEO TT&C application, especially for KOMPSAT (KOrea Multi-Purpose SATellite). To cope with requirements such as high handling power, low insertion loss, air-cavity resonator with high quality factor was considered as one of design drivers. Design was started with predicting unloaded Q and equivalent circuit from the structure of air-cavity resonator. For the convenience of adjustment, the coupling factor placed between resonators was estimated from COTSEM (Electro-Magnetic) simulator, EESOF $ADS^{TM}$, and expressed with 2-order polynomial regression. To improve the isolation between transmitting part (Tx) and receiving part (Rx), the inductive and capacitive attenuation poles were inserted between $4^{th}\;and\;6^{th}$ resonator respectively. The fabricated diplexer consists of two bandpass filters and each filter has eight resonants. From the measurement, it was shown that major requirements such as 0.5dB of insertion loss, 20dB of return loss and 100dB of isolation were fully satisfied within passband.

New Columnar Apple Variety 'Tinkerbell' for Pollenizer (사과 무측지성 수분수용 신품종 '팅커벨')

  • Kwon, Soon-Il;Kwon, Young Soon;Park, Jong-Taek;Kim, Mok-Jong;Kim, Jeong-Hee
    • Journal of Bio-Environment Control
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    • v.25 no.3
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    • pp.173-176
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    • 2016
  • This research was performed to breed new columnar-typed apple variety for pollinator in apple orchard. We cross-fertilized 'Hongro' that was an ovary parent and 'Maypole' a pollen parent in 2003. We gathered seeds in 2003 and sowed after breaking of dormancy in 2004. Seedlings was been growth and development till flowering. After fruit setting, We investigated characteristics of growth and fruit including mating compatibility from 2010 to 2012, then finally selected '03-2-95' named 'Tinkerbell' in 2012, registered as new variety on Korea Seed & Variety Service in 2015. The full bloom stage of 'Tinkerbell' was later 2 days then of 'Maypole'. Tree habit of 'Tinkerbell' was alike to of 'Maypole', for example weak tree vigor, columnar type. But there were many different characteristics between 'Tinkerbell' and 'Maypole'. Fruit shape of 'Tinkerbell' was ovoid whereas of 'Maypole' was ellipsoid. Fruit of 'Tinkerbell' was bigger, smoother skin, no waxy bloom than of 'Maypole'. Fruit of 'Tinkerbell' was more delicious than of 'Maypole' because of having higher soluble sugar content and lower titratable acidity. 'Tinkerbell' was excellent pollinator in apple orchard. Because of having high fruit setting rate with major apple varieties and a narrow tree width that was advantageous as pollinator in apple high density system.

IL-1Ra Elaboration by Colchicine Stimulation in Normal Human Bronchial Epithelial Cells (정상 인체 기관지 상피세포에서 콜히친의 Interleukin-1 수용체 길항제 생성자극)

  • Lee, Jae Hyung;Kim, Sang Heon;Kim, Tae Hyung;Sohn, Jang Won;Yoon, Ho Joo;Shin, Dong Ho;Park, Sung Soo
    • Tuberculosis and Respiratory Diseases
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    • v.63 no.2
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    • pp.145-153
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    • 2007
  • Background: Asthma is a syndrome that is characterized by a variable degree of airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Colchicine is an inexpensive and safe medication with unique anti-inflammatory properties. IL-1Ra (Interleukin-1 receptor antagonist) mediates the anti-inflammatory effect in human inflammatory diseases, including asthma. This study examined whether IL-1Ra mediates the anti-inflammatory effect of colchicine in normal human bronchial epithelial cells (NHBE), RAW 264.7 cells (murine macrophage cell line), and a mouse lung. Methods: NHBE, RAW 264.7 cells and BALB/c mice were stimulated with colchicine, and the increase in the IL-1Ra level was estimated by ELISA, Western analysis and RT-PCR analysis. Results: Colchicine stimulated NHBE and RAW 264.7 cells to release IL-1Ra into the supernatant in a dose-and time-dependent manner. The major isoform of IL-1Ra in NHBE and RAW 264.7 cells is type I icIL-1Ra, and sIL-1Ra, respectively. IL-1Ra up-regulation was blocked by PD98059, a specific inhibitor in MAPK pathways. Colchicine also stimulated the secretion of IL-1Ra into the bronchoalveolar lavage (BAL) fluid of BALB/c mouse. Conclusion: Colchicine stimulates an increase in the IL-1Ra level both in vivo and in vitro, and might have an anti-inflammatory effect.

Role of Endogenous Histamine on the Pathogenesis in the Endotoxin-Induced Acute Lung Injury (내독소로 유도되는 급성폐손상의 발병기전에서 내인성 히스타민의 역할)

  • Kim, Tae-Hyung;Kim, Eun-Kyung;Yoon, Ho Joo;Kim, Mi Jung;Choi, Jeoung Eun;Oh, Yeon Mok;Shim, Tae Sun;Lim, Chae Man;Lee, Sang Do;Kim, Woo Sung;Kim, Dong-Soon;Kim, Won Dong;Koh, Younsuck
    • Tuberculosis and Respiratory Diseases
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    • v.54 no.1
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    • pp.91-103
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    • 2003
  • Background : Histamine is widely distributed in the lung. It increases capillary permeability and the P-selectin expression on vascular endothelial cell surfaces. We studied the role of endogenous histamine on the pathogenesis of endotoxin-induced acute lung injury (ALI) in rats. Methods: We instilled either normal saline (control group) or lipopolysaccharide (3 mg/Kg, LPS group) to tracheas of Sprague-Dawley rats. H1-receptor blocker (mepyramine, 10 mg/Kg, H1RB group), H2-receptor blocker (ranitidine, 10 mg/Kg, H2RB group), and H3-receptor blocker (thioperamide, 2 mg/Kg, H3RB group) were administered through vein or peritoneum along with intratracheal LPS administration. Statistical significance was accepted at p<0.05. Results : LPS increases the histamine level in BAL fluid significantly at 2 h after the treatment compared with control group. LPS significantly increases protein concentration, PMN cell count in bronchoalveolar lavage (BAL) fluid, and myeloperoxidase (MPO) activity in the lung tissue at 6 h compared to control group. PMN cell count in BAL fluid and MPO activity in lung tissue were significantly lower in H2RB-group compared to LPS-group. However, protein concentration in BAL fluid showed no significant differences between the LPS alone and LPS with histamine receptor blockade. Conclusions : Endogenous histamine might be involved in the recruitment of PMNs in LPS-induced ALI via H2 receptor. However, its role in ALI would not be significant in this model.

A Study on the Kinetics and Mechanism of the Hydrolysis of 5,6-Dihydro-1,4-thiazine Derivatives (5,6-Dihydro-1,4-thiazine 유도체의 가수분해 메카니즘과 반응속도론적 연구)

  • Lee, Gwang Il;Lee, Seok U;Gwak, Cheon Geun;Jang, Byeong Man;Kim, Yeong Ju;Lee, Gi Chang
    • Journal of the Korean Chemical Society
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    • v.38 no.5
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    • pp.366-371
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    • 1994
  • The kinetics of the hydrolysis of 5,6-dihydro-1,4-thiazine derivatives was investigated by ultraviolet spectrophotometry in $H_2O$ at 25$^{\circ}C$. A rate equation which can be applied over a wide pH range was obtained. The substituent effects on the hydrolysis of 5,6-dihydro-1,4-thiazine derivatives were studied and the rate of hydrolysis was shown to be accelerated by electron donating groups. Final product of the hydrolysis was 2-(N-acetylaminoethylthio)-acetoacetanilide enol from Judging from the results of the rate equation, general base effect, activation parameters and final products, the hydrolysis of 5,6-dihydro-1,4-thiazine derivatives seemed to be initiated by the neutral $H_2O$ molecule which does not dissociate at pH below 10.0, but proceeded by the hydroxide ion at pH above 11.0, and those two reactions occurred competively at pH 10.0∼11.0 range. On the basis of these findings a plausible mechanism for the hydrolysis of 5,6-dihydro-1,4-thiazine derivative was proposed.

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Formation of Active Oxygen in Meat Emulsion System (냉장저장중 고기모형유화물에서 활성산소의 생성에 관한 연구)

  • Park, Hyung-Il;Chung, Myung-Sup;Lee, Moo-Ha;Lee, Sung-Ki
    • Korean Journal of Food Science and Technology
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    • v.33 no.1
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    • pp.1-6
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    • 2001
  • Emulsion products with water soluble protein were exposed under light at $5^{\circ}C$ for 8 days. Peroxide value (POV) was increased significantly at the bigining of storage and 2-thiobarbituric acid (TBA) value also increased until 4 days of storage with increase of the production of carbonyl compounds, suggesting that the condition was reacted different from that of the lipid autoxidation. The reaction was similar to the flavor reversion that usually produced from the bigining of soybean oil oxidation. The reason might be the meat pigment, myoglobin, oxidation and it would be due to the singlet oxygen rather than superoxide anion. When the light was excluded general pattern was similar but the production of oxidation products were smaller than that when the sample was exposed under light. The effect of the singlet oxygen was also smaller which meant that the singlet oxygen produced during emulsion process may affect on the flavor reversion at the bigining of storage. The POV of the emulsion without water soluble protein increase gradually by storage and the results indicated that the degradation rate of the peroxides were lower than the sample with water soluble protein. Especially after 4 days of storage, production of carbonyl compounds were decreased. During storage it would be possible to produce the singlet oxygen and the sensitizer from the plants that can be produced during decoloration of soybean oil may be responsible for it. When the light was excluded the production of oxidation products were reduced at the begining of storage and the effect of quencher also was not detected. Therefore the results indicated that the light can accelerate the lipid oxidation.

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