• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2002.12a
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• pp.126-129
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• 2002

An intelligent digital redesign technique (IDR) for the observer-based output feedback Takagi-Sugeno (T-5) fuzzy control system with fuzzy outputs is developed. The considered IDR condition is cubically parameterized as convex minimization problems of the norm distances between linear operators to be matched.'rho stability condition is easily embedded and the separations principle is explicitly shown.

• Journal of the Korean Magnetic Resonance Society
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• v.27 no.3
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• pp.17-22
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• 2023

Bloom syndrome protein (BLM) is a pivotal RecQ helicase necessary for genetic stability through DNA repair processes. Our investigation focuses on the N-terminal region of BLM, which has been considered as an intrinsically disordered region (IDR). This IDR plays a critical role in DNA metabolism by interacting with other proteins. In this study, we performed triple resonance experiments of BLM_220-300 and presented the backbone chemical shifts. The secondary structure prediction based on chemical shifts of the backbone atoms shows the region is disordered. Our data could help further interaction studies between BLM_220-300 and its binding partners using NMR.

• Korean Journal of Agricultural Science
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• v.44 no.1
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• pp.123-132
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• 2017

Nowadays, many people suffer from stress because of their jobs, studies, traffic, etc. Daily stress may cause many diseases (Garrett, 1991). One of the methods for reducing stress is experiencing a natural environment (Frumkin, 2001). Cibodas botanical garden (CBG) is one of the most famous travel destinations in Bogor, Indonesia. CBG has the potential for tourism activities. However, an economic assessment is required to verify their sustainability. The research objectives of this study were to identify the characteristics of tourism utilization in CBG, to analyze the economic tourism value of CBG, and to measure the effectiveness of traveling to a natural environment for reducing stress. The research method used was the survey. This study used three data analysis methods: (1) descriptive analysis which was used to identify the characteristics of tourists, (2) travel cost method (TCM), and (3) contingent valuation method (CVM). Results showed some differences in the characteristics of foreign and domestic tourists respondents in age, educational background, income level, number of dependents, and the frequency of their visits. CBG has a high economic value, amounting to IDR (Indonesian Rupiah) 5,508,932,605,405 or approximately USD (United State Dollar) 413,000,000. WTP (Willingness to Pay) of domestic tourist respondents was IDR 29,702 or USD 2.2 per visit, while the value of foreign tourist respondents reached IDR 39,700 or USD 2.9 per visit. Respondents found it preferable to pay more for tickets (WTP value) than to buy medication to reduce their stress.

• Earthquakes and Structures
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• v.5 no.1
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• pp.83-109
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• 2013

A simple damper optimization method is proposed to find optimal damper allocation for shear buildings under both target added damping ratio and interstorey drift ratio (IDR). The damping coefficients of added dampers are considered as design variables. The cost, which is defined as the sum of damping coefficient of added dampers, is minimized under a target added damping ratio and the upper and the lower constraint of the design variables. In the first stage of proposed algorithm, Simulated Annealing, Nelder Mead and Differential Evolution numerical algorithms are used to solve the proposed optimization problem. The candidate optimal design obtained in the first stage is tested in terms of the IDRs using linear time history analyses for a design earthquake in the second stage. If all IDRs are below the allowable level, iteration of the algorithm is stopped; otherwise, the iteration continues increasing the target damping ratio. By this way, a structural response IDR is also taken into consideration using a snap-back test. In this study, the effects of the selection of upper limit for added dampers, the storey mass distribution and the storey stiffness distribution are all investigated in terms of damper distributions, cost function, added damping ratio and IDRs for 6-storey shear building models. The results of the proposed method are compared with two existing methods in the literature. Optimal designs are also compared with uniform designs according to both IDRs and added damping ratios. The numerical results show that the proposed damper optimization method is easy to apply and is efficient to find optimal damper distribution for a target damping ratio and allowable IDR value.

• Molecules and Cells
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• v.43 no.11
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• pp.899-908
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• 2020

Intrinsically disordered proteins or regions (IDPs or IDRs) are widespread in the eukaryotic proteome. Although lacking stable three-dimensional structures in the free forms, IDRs perform critical functions in various cellular processes. Accordingly, mutations and altered expression of IDRs are associated with many pathological conditions. Hence, it is of great importance to understand at the molecular level how IDRs interact with their binding partners. In particular, discovering the unique interaction features of IDRs originating from their dynamic nature may reveal uncharted regulatory mechanisms of specific biological processes. Here we discuss the mechanisms of the macromolecular interactions mediated by IDRs and present the relevant cellular processes including transcription, cell cycle progression, signaling, and nucleocytoplasmic transport. Of special interest is the multivalent binding nature of IDRs driving assembly of multicomponent macromolecular complexes. Integrating the previous theoretical and experimental investigations, we suggest that such IDR-driven multiprotein complexes can function as versatile allosteric switches to process diverse cellular signals. Finally, we discuss the future challenges and potential medical applications of the IDR research.

• Environmental Engineering Research
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• v.23 no.1
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• pp.114-119
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• 2018

Yarn dyed wastewater has to be treated prior to disposal into the water bodies due to its high content of harmful organic compounds. In this study, the performance of Chemical Oxygen Demand (COD) removal and kinetic rate constant are investigated via hybrid electrocoagulation-Fenton in a continuous system using wastewater discharged from a yarn dyed industry in Surabaya city. The wastewater was treated in a batch mode using electrocoagulation to reduce Total Suspended Solid, followed by Fenton method in a continuous system to reduce COD level. Various Fe(II) feeding modes, molar ratio of $Fe(II)/H_2O_2$, initial pH of wastewater, and flow rate are used in this study. The results show that COD removal process obeys a pseudo-first order kinetics. At $Fe(II)/H_2O_2$ ratio of 1:10, initial wastewater pH of 3.0, and feed flow rate of 30 mL/min, the COD removal efficiency was observed to be 80%, and the kinetic rate constant is $0.07046min^{-1}$. The chemical cost for the treatment estimated to be IDR 160 per L wastewater, which is cheaper than the previously reported batch system of IDR 256/L.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.3
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• pp.39-43
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• 2010

The main objective of this research is to develop a mechanistic performance predictive model for fatigue cracking of asphalt-aggregate mixtures. Controlled-stress diametral fatigue tests were performed to characterize fatigue cracking of asphalt-aggregate mixtures. Performance prediction model for fatigue cracking was developed using the internal damage ratio (IDR) growth method. In the IDR growth method, the general concepts of the dissipated energy, the reference tensile strain, the threshold tensile strain, and the strain shift factor were introduced. The source of the dissipated energy in the fatigue test is from the intrinsic viscoelastic material property of an asphalt concrete mixture and the damage growth within the asphalt concrete specimen. In controlled-stress mode test, the dissipated energy is gradually increased with an increasing number of load applications.

• Journal of the Korean Institute of Intelligent Systems
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• v.18 no.1
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• pp.60-65
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• 2008

In this paper, we concern the stability of smart space by using the robust digital controller. The proposed methodologies are based on the intelligent digital redesign (IDR). More precisely, we represent the nonlinear and uncertain analog system as the Takaki-Sugeno (T-S) fuzzy model. Then the IDR problem can be reduced to find the digital gains minimizing the norm distance between the closed-loop states of the analog and digital control. Its constructive conditions are expressed as the linear matrix inequalities (LMIs). At last, a numerical example, HVAC system, is demonstrated to visualize the feasibility of the proposed methodology.

• Journal of Broadcast Engineering
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• v.13 no.1
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• pp.119-127
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• 2008

Transmission of video over Internet or wireless network requires coded stream capable of adapting to dynamic network conditions instantly. To meet this requirement, various scalable video coding schemes have been developed, among which the Scalable Video Coding (SVC) extension of the H.264/AVC is the most recent one. In comparison with the scalable profiles of previous video coding standards, the SVC achieves significant improvement on coding efficiency performance. For adapting to dynamic network bandwidth, the SVC employs inter-layer switching between different temporal, spatial or/and fidelity layers, which is currently supported with instantaneous decoding refresh (IDR) access unit. However, for real-time adaptability, the SVC has to frequently employ the IDR picture, which dramatically decreases the coding efficiency. Therefore, an extension of SP picture from the AVC to the SVC for an efficient inter-layer switching is investigated and presented in this paper. Simulations regarding the adaptability to dynamic network bandwidth are implemented. Results of experiment show that the SP picture added SVC provides an average 1.2 dB PSNR enhancement over the current SVC while providing similar adaptive functionality.

• Earthquakes and Structures
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• v.17 no.3
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• pp.271-282
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• 2019

Knowing the response of buildings to earthquakes is very important in order to ensure that a structure is able to withstand a given level of ground shaking. Thus, nonlinear dynamic earthquake engineering analyses are unavoidable and are preferable procedure in the seismic assessment of buildings. In order to estimate seismic performance on the basis of the hazard at the site where the structure is located, the selection of appropriate seismic input is known to be a critical step while performing this kind of analysis. In this paper, seismic analysis is performed for a four-story reinforced concrete ISPRA frame structure which is designed according to Eurocode 8 (EC8). A total of 90 different earthquake scenarios were selected, 30 for each of three target spectrums, EC8 spectrum, Uniform Hazard Spectrum (UHS), and Conditional Mean Spectrum (CMS). The aim of this analysis was to evaluate the average maximum Inter-story Drift Ratio (IDR) for each target spectrum. Time history analysis for every earthquake record was obtained and, as a result, IDR as the main measure of damage were presented in order to compare with defined performance levels of reinforced concrete bare frames.