• Korean Journal of Community Nutrition
• /
• v.27 no.3
• /
• pp.245-253
• /
• 2022

Objectives: This study was conducted to find out if the dietary iron intake of Koreans estimated by 2 different methods (iron content sources) using the food intake data from the Korea National Health and Nutrition Examination Survey (KNHANES) are comparable. One method was based on the KNHANES's Food & Nutrient Database (FND) derived mainly from the Korean Food Composition Table and the other used the iron content (IC) of food samples processed in the Korean Total Diet Study (KTDS). Methods: Dietary intake data from the 2013-2016 KNHANES was used to select representative foods (RFs) in KTDS for iron analysis. Selection of the RFs and cooking methods for each RF (RF × cooking method pair) was performed according to the 'Guidebook for Korean Total Diet Studies' and resulted in a total of 132 RFs and 224 'RF × cooking method' pairs. RFs were collected in 9 metropolitan cities nationwide once or twice (for those with seasonality) in 2018 and made into 6 composites each, based on the origin and season prior to cooking. Then, the RF composites prepared to a 'table ready' state for KTDS were analyzed by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). Dietary iron intake of the Korean population was estimated using only RFs' intake data based on the 2 sources of iron content, namely FND-KNHANES and IC-KTDS. Results: RFs in KTDS covered 92.0% of total food intake of Koreans in the 2016-2018 KNHANES. Mean iron intake of Koreans was 7.77 mg/person/day by IC-KTDS vs 9.73 mg/person/day by FND-KNHANES. The major food groups contributing to iron intake were meats (21.7%), vegetables (20.5%), and grains & cereals (13.4%) as per IC-KTDS. On the other hand, the latter source (FND-KNHANES) resulted in a very different profile: grains & cereals (31.1%), vegetables (16.8%), and meats (15.3%). While the top iron source was beef, accounting for 8.6% in the former, it was polished rice (19.2%) in the latter. There was a 10-fold difference in the iron content of polished rice between 2 sources that iron intakes excluding the contribution by polished rice resulted in very similar values: 7.58 mg/person/day by IC-KTDS and 7.86 mg/person/day by FND-KNHANES. Conclusions: This study revealed that the dietary iron intake estimated by 2 different methods were quite comparable, excluding one RF, namely polished rice. KTDS was thus proven to be a useful tool in estimating a 'closer-to-real' dietary intake of nutrients for Koreans and further research on various nutrients is warranted.

• Journal of Marine Life Science
• /
• v.6 no.2
• /
• pp.66-72
• /
• 2021

We investigated the antioxidant and hepatoprotective effects of extracts from the Undaria pinnatifida and Costaria costata against ethanol-induced oxidative damage. The total polyphenol and flavonoid contents were highest in the 70% ethanol extract from Undaria pinnatifida and Costaria costata. Also, the radical scavenging activity of DPPH (IC₅₀ 0.33± 0.21, 0.48±0.47 mg/ml) and ABTS (IC₅₀ 0.34±0.30, 0.47±0.17 mg/ml) in the 70% ethanol extract was higher than that of the hot water and 10% ethanol extracts. To determine the hepatoprotective effects of extracts in ethanol-induced oxidative damage, cell viability was measured using an MTT assay. In the pre-treatment of Undaria pinnatifida and Costaria costata hot water extracts, the concentration-dependent increased the cell viability compared with the ethanol treated cells (73.95%) by 89.91~97.63% and 84.99~90.54%, respectively. The data suggests that 70% ethanol extracts have antioxidant activity and hot water extracts exhibit hepatoprotective effects. Therefore, Undaria pinnatifida and Costaria costata may be considered potential agents for control ethanol-induced liver damage.

• Journal of Digital Contents Society
• /
• v.19 no.6
• /
• pp.1185-1195
• /
• 2018

Industrial Control System (ICS) is a system that carry out monitoring and controls of industrial control process and is applied in infrastructure such as water, power, and gas. Recently, cyber attacks such as Brutal Kangaroo, Emotional Simian, and Stuxnet 3.0 have been continuously increasing in ICS, and these security risks cause damage of human life and massive financial losses. Attacks on the control layer among the attack methods for ICS can malfunction devices of the field device layer by manipulating control commands. Therefore, in this paper, we propose a mechanism that apply the SDN between the control layer and the field device layer in the industrial control system and to determine whether the control command is legitimate or not and we show simulation results on a simply composed control system.

• The Science & Technology
• /
• v.33 no.6 s.373
• /
• pp.88-89
• /
• 2000

오늘날 세계 전자공업시장 규모는 1조달러선을 넘어섰고 마침내 세계 최대 규모의 산업으로 발돋움할 날도 멀지 않았다. 이른바 전자산업혁명의 중추적인 역할을 하고 있는 집적회로는 21세기 디지털시대의 핵심체인 마이크로칩의 '모태' 이기도 하다. 20세기 최대의 발명으로 평가되고 있는 집적회로를 40여년 전 수더분한 인상의 말수가 적은 재크 킬비라는 당시 '무명'의 한 청년이 발견하리라고 생각했던 사람은 아무도 없었다.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2021.05a
• /
• pp.205-208
• /
• 2021

4차 산업혁명 시대에는 사이버 시스템과 물리 시스템이 연결된다. ICS(산업제어시스템)에서는 기존의 위협 외에 IT 환경에서 발생할 수 있는 보안 위협에 직면하게 된다. 따라서 OT와 IT가 결합되는 환경에서의 위협에 대한 대응 기술이 필요하다. 본 논문에서는 OT/IT 네트워크에서의 핑거프린팅을 추출하고 이를 기반으로 OT 위협을 탐지하는 구조를 설계한다. 이를 통하여 ICS에서의 보안 위협에 대응하고자 한다.

• The Science & Technology
• /
• v.33 no.10 s.377
• /
• pp.25-27
• /
• 2000

20세기 인류생활에 가장 큰 공헌을 한 공학기술은 전기와 전자공학 분야이다. 전기ㆍ전자공학의 뿌리를 찾는다면 1백년 전 2천개의 특허를 낸 에디슨의 업적에서 비롯된다. 오늘날 우리에게는 산업혁명에 견주어지는 기술혁명을 겪고 있는데 이러한 기술혁명은 진공관으로부터 트렌지스터, IC, VLSI로 변천해오면서 발전된 반도체기술을 기반으로 디지털기술이 발전되었고 이를 통해 생겨난 디지털 혁명이 바로 그것이다.

• Proceedings of the KIPE Conference
• /
• 2017.07a
• /
• pp.28-29
• /
• 2017

기존의 위상천이 풀 브리지 DC/DC 컨버터의 경우 변압기의 누설 인덕턴스와 2차 측 정류 다이오드의 기생 출력 커패시턴스 사이의 공진으로 인하여 정류 다이오드 양단에 큰 공진 전압이 발생하며, 이는 소자의 신뢰성 저하 및 시스템의 전력 변환 효율을 감소시킨다. 반면 LLC 공진형 컨버터는 2차 측에서 발생되는 공진 에너지가 출력 커패시터로 흡수되지만 경 부하시에 높은 스위칭 주파수로 인하여 효율이 저감되며, 출력 전압을 제어하기 위해 추가적인 부하저항이 요구된다. 따라서 최근에는 LLC 공진형 컨버터로 동작시키면서도 PWM 제어를 통해 출력전압을 제어하는 방법이 연구되고 있으나, 새로운 게이트 구동 방식을 위해 DSP 제어를 사용하고 있다. 따라서 본 논문에서는 산업에서 많이 사용되고 있는 아날로그 IC를 통해 동일한 동작 및 성능을 구현시킬 수 있는 방법에 대하여 제안한다. 본 논문에서는 제안된 방식의 타당성을 검증하기 위하여 이론적으로 분석하며, 6.6kW급 시작품을 제작하여 제안방식의 타당성을 검증하였다.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.21 no.4
• /
• pp.129-134
• /
• 2021

A power tool is a tool used to manufacture and process various structures using a motor that is a power source. Using a motor that uses electricity as a power source, a reduction device, power transmission and conversion device functions are built-in to make the tool rotate, reciprocate, and vibrate. It is a work tool designed to assist the user's movement skills. In the case of Korea, the power tool industry has a short history and is lagging behind advanced countries such as Germany, the United States, and Japan in terms of technology level, market share, and recognition. In addition, electric drivers used in Korea are foreign products from the US and European countries, and the domestic market also prefers 100% foreign companies, and multinational companies are investing a lot in the domestic market. Therefore, technological development must follow in order to develop domestic technology and secure a consistently high market share. The purpose of this thesis is to design a motor driver with high output performance of motor performance, miniaturization, and high speed in accordance with the basic performance requirements of power tools, and finally research developments that can be applied to industrial and medical applications.

• The Journal of Korean Medicine
• /
• v.43 no.1
• /
• pp.33-41
• /
• 2022

Objectives: Drug-induced blockade of the human ether-à-go-go related gene (hERG) potassium ion channel causes acquired long QT syndrome, which is known to cause cardiac arrhythmias and be fatal. To establish safety evidence of herbal formulae, we evaluated the effects of 31 herbal formulae on hERG channel activity. Methods: The current through hERG channel was measured by changing the membrane voltage before and after treatment with 31 herbal formulae in HEK 293 cell overexpressing hERG channel using a whole-cell patch clamp system. The current-voltage curves and the activity curves were fitted, and the hERG activity and 50% inhibitory concentration (IC₅₀) according to each herbal formula were calculated. Results: Chokyungjongok-tang, Oncheong-eum, and Cheongsangbangpung-tang strongly inhibited the hERG activity, with IC₅₀ values of 67.67, 141.2, and 296.3 ㎍/mL, respectively. Yeonkyopaedok-san, Eunkyo-san, Ukgan-san gajinphibanha, Daegunjoong-tang (except Oryzae gluten), Insamyangyoung-tang, Banhahubak-tang, SokyungHwalhyul-tang, Jodeung-san, Hyeonggaeyeongyo-tang, and Bangkeehwangkee-tang weakly inhibited hERG activity, with IC₅₀ values ranging from 400 to 1000 ㎍/mL. The other 18 herbal formulae showed very weak hERG activity inhibition of less than 50% at the highest concentration (1000 ㎍/mL). Conclusion: This study provided safety information on cardiotoxicity by cardiac arrhythmia risk assessment of herbal formulae, and is expected to be a reference data for predicting the safety and risk of herbal formulae.

• Food Science of Animal Resources
• /
• v.32 no.5
• /
• pp.652-658
• /
• 2012

This study was carried out to identify the ACE (Angiotensin converting enzyme) inhibitory activity of casein hydrolysates for development of anti-hypertensive hydrolysates. Sodium caseinate was treated with six kinds of commercial proteases such as Flavourzyme, Protamex, Neutrase 1.5, Alcalase, Protease M, and Protease S for 8 h individually, and was then treated with the enzyme combination for 4 h at $45^{\circ}C$. The hydrolysate which had the highest ACE inhibitory effect was then hydrolysed successively with three digestive enzymes: pepsin, trypsin, and ${\alpha}$-chymotrypsin, at $37^{\circ}C$ for 4 h under conditions mimicking those of the gastrointestinal tract. UF (ultra filtration) treatment was applied to one of the secondary hydrolysates to determine ACE inhibitory activity. When sodium caseinate was hydrolysed by commercial proteases, the degree of hydrolysis (DH) showed 2.54 to 4.25% and after secondary hydrolysis, DH showed 4.30 to 5.22%. ACE inhibitory activity and $IC_{50}$ values decreased, and inhibition rates increased during hydrolysis. Protamex treatment showed the lowest $IC_{50}$ value ($516{\mu}g/mL$) and Flavourzyme hydrolysate showed the highest $IC_{50}$value ($866{\mu}g/mL$). As the first hydrolysate was treated with Flavourzyme, the ACE inhibitory activity increased. Neutrase hydrolysate had the highest activity with an $IC_{50}$ value ($282{\mu}g/mL$). When Neutrase plus Flavourzyme treatment was hydrolyzed by digestive enzymes, the $IC_{50}$ value ($597{\mu}g/mL$) was decreased statistically (p<0.05). As Neutrase plus Flavourzyme hydrolysate is treated by UF with MW cut-off 10,000, permeate showed $273{\mu}g/mL$ of $IC_{50}$ value, showed no difference, but retentate which has over MW 10,000 showed statistically different $IC_{50}$ value, $635{\mu}g/mL$ (p<0.05).