• Journal of Animal Science and Technology
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• v.46 no.2
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• pp.217-226
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• 2004

This study was canied out to evaluate the quality characteristics of the fermented pork with Korean traditional seasonings. The samples, outside muscle of pork ham were cut to cube(7 ${\times}$ 12 ${\times}$ 2cm) and five Korean traditional seasonings such as garlic paste(TI), pickled Kimchi(T2), pickled Kimchi juice(T3), soybean paste(T4), red pepper paste(T5) were seasoned by the proportions of meat to seasonings(1 : 1). The seasoned samples were fennented at - 1 ${\pm}$ 1$^{\circ}C$ for 20 days. According to proximate composition analysis, all pork samples contained protein 20 ${\sim}$ 22%, fat 3 ${\sim}$ 5%, moisture 64 ${\sim}$ 70% and ash 1.8 ${\sim}$ 2.0%. However, T5 had high crude fat level and relatively low moisture content. The highest pH among treatments was shown in TI whereas T3 showed the lowest. Water holding capacity(WHC) of T4 and T5 were higher, while those values were lower in T3 compared with other treatment. Shear force value was the highest in T5, while it was the lowest in T4. TBARS value of T3 was the highest, while that was the lowest in T4. Moreover the highest VBN value was observed in T4 due to fermentation of soy protein. However, the lowest VBN value shown in Tl indicated the inhibition of protein degradation by the garlic. The highest saccarinity was shown in T5 but it was the lowest of in T3. Salinity was shown to be high in T2 and low in T5. $L^*$ values of T4 was higher both at the surface and inner side of samples than the others but T5 showed the lowest value. T2 showed the highest $a^*$ value but T4 and T5 showed the lowest. In the result of sensory evaluation for cooked meat, T5 had the highest score in all item including overall acceptability, while T4 had the lowest score. Unsaturated fatty acid(UFA) ratio of T5 and n were 72.16 and 69.93 respectively, and the ratio of UFA/Saturated fatty acid(SFA) were higher in the order of T5 >T4> T3 >Tl >T2. Overall quality characteristics were higher in the order of T5 >T2 >Tl >T4 >T3.

• Journal of Life Science
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• v.31 no.10
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• pp.898-904
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• 2021

Locusta migratoria is a widespread locust species in many parts of the world and is considered an alternative source for the production of protein for value-added ingredients. We previously identified putative antimicrobial peptides derived from L. migratoria through an in silico analysis of its transcriptome. However, its anti-inflammatory effect has not been studied. In this study, we investigated the anti-inflammatory activities of the antimicrobial peptide locustacin (KTHILSFFPSFLPLFLKK-NH₂) derived from L. migratoria on lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. Locustacin (50, 100, and 200 ㎍/ml) significantly reduced the production of nitric oxide (NO) in LPS-stimulated macrophages without any cytotoxicity. Locustacin also inhibited the mRNA and protein expression of pro-inflammatory mediators, such as inducible NO synthase and cyclooxygenase-2, in contrast to the presence of LPS alone. Locustacin decreased the release of LPS-induced pro-inflammatory cytokines, including interleukin (IL)-6 and IL-1β, and their gene expression in a dose-dependent manner. Furthermore, locustacin (100 and/or 200 ㎍/ml) inhibited phosphorylation levels of extracellular signal regulated kinase, p38, and c-Jun N-terminal kinase. Locustacin also suppressed the degradation of inhibitory kappa B alpha, which was considered to be an inhibitor of nuclear factor kappa B (NF-κB). Collectively, these results demonstrate that locustacin can exert anti-inflammatory effects through the inhibition of mitogen-activated protein kinase (MAPK) phosphorylation, activation of NF-κB, and downstream inflammatory mediators in LPS-stimulated macrophage cells.

• Journal of Food Hygiene and Safety
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• v.26 no.2
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• pp.107-113
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• 2011

Plantago asiatica L. (PA), which is widely distributed in Korea, Japan and China, has traditionally been used as a popular folk medicine for the treatment of liver diseases. A variety of activities of PA was reported, that is hepatoprotective, anti-inflammatory, anti-glycation and anti-oxidant effect. Ferric nitrilotriacetate (Fe-NTA) is a potent nephrotoxic agent and has been reported to induce renal proximal tubular necrosis. In the present study, pre-treatment with PA extract (PAE) in Wistar rat followed by Fe-NTA i.p. treatment (13.5 mg Fe/kg body weight) was performed to detect the renal protective effect of PAE. Only Fe-NTA treated group showed increases in the level of serum blood urea nitrogen (BUN) and serum creatinine (Cr), and renal tissue malondialdehyde (MDA), product of lipid peroxidation. Moreover, the level of biomarkers indicate the antioxidants status, reduced glutathione (GSH), glutathione-S-transferase (GST) and glutathione reductase (GR) were decreased. However, PAE pre-treated group showed decreases in the levels of serum BUN, serum Cr and renal tissue MDA in concentration dependent manner and increases in the level of GSH, GST and GR. These results are significantly different (p < 0.05) to the other groups. Our data suggest that PAE may be used as an chemopreventive material against Fe-NTA-mediated renal oxidative stress.

• The Korean Journal of Food And Nutrition
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• v.28 no.3
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• pp.369-375
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• 2015

This study was performed to investigate the physiological activities of Ginkgo biloba sarcotesta extracts before and after heat treatment. G. biloba sarcotesta was heated at $130^{\circ}C$ for 2 h and extracted with water, 70% ethanol and 80% methanol. ABTS and DPPH radical scavenging activities increased after heating in the water (14.95 mg AAE/g and 7.36 mg TE/g) and ethanol extracts (12.20 mg AAE/g and 6.23 mg TE/g). ${\alpha}$-Glucosidase inhibitory activity decreased after heating in all but the water extract. Angiotensin converting enzyme I inhibitory activities decreased after heating in all extracts. Nitric oxide production inhibitory activity increased from 12.40~44.55% of the raw sample to 40.76~72.39% of the heated sample at a concentration of $200{\mu}g/mL$. Lipid accumulation inhibitory activities were similar before and after heat treatment. The highest antiproliferative effects on MCF-7 human breast cancer cell lines were observed in 80% methanol extract in the heated sample. Cell viability at concentrations of 25, 50, 100, and $200{\mu}g/mL$ measured 34.88, 17.58, 8.44 and 10.48%, respectively. From the results, the antioxidant and antiproliferative activities of G. biloba sarcotesta extracts increased with heat treatment, and research on the identification of the structure for the active compounds are needed in further studies.

• Journal of the Korean Society of Food Science and Nutrition
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• v.31 no.5
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• pp.862-870
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• 2002

The purpose of this study is to verify the relation between vegetarian diet and the risk factors of cardiovascular disease. The subjects of the study were 127 Buddhist nuns (age:23～79y) from Oonmoon Temple in Choungdo District Gyeongsang Bookdoo Province and 118 Buddhist nuns practicing Zen meditation at Soodeok Temple in Yeosan District Chongcheong namdoo Province. For control subjects, 235 healthy female adults (age:23～79y) were selected. They were the teachers, the nurses of the hospital of Gyeongsang National university and the housekeepers living in chinju Gyeongsang Namdoo Province. The period of this study was from October 1996 to February 1997. The contents were consisted of food consumption survey, anthropometric measurement, estimating amount of energy expenditure, physical activity and clinical examination. Results were summarized as follows: The mean ages of the subjects were 44.2y for vegetarians and 40.5y for non-vegetarians, respectively. average body mass index (BMI) of vegetarians and non-vegetarians were 22.47 adn 21.08, WHR 0.85 and 0.84, percentage of body fat 28.79 and 26.55 respectively. The average duration of vegetarian diet of the vegetarians was 13.16 years. Levels of total cholesterol, LDL-cholesterol, atherogenic index (AI), diastolic blood pressure, blood sugar and HDL-cholesterol of non-vegetarians were significantly higher (p<0.01) than those of vegetarians, but ration of HDLcholesterol/total-cholesterol was lower in non-vegetarians. In both of subjects, BMI, WHR, RBW, %BF had sig-nificant positive correlations with triglyceride, total cholesterol, LDL-cholesterol and AI. BMI, WHR had sig-nificant positive correlation with systolic blood pressure. BMI, WHR had significant negative correlation with HDL-cholesterol. In summary, vegetable diet can contribute to lowering serum lipid level, atherogenic index (AI),systolic blood pressure, blood sugar.

• Journal of Hospice and Palliative Care
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• v.2 no.2
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• pp.114-124
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• 1999

Purpose : To clarify the relation between psychosocial variables and cancer in Korea. Methods : Case-control study. Participants: 239 subjects in 2 university hospitals in Seoul completed a series of psychometric instruments(the Olson's FACES III and the Lee's 98-items life event scale). Results : In bivariable analysis, there were statistically significant difference in age and economic status(income): marginal significance in education status and marital status between the cases and controls. The family function type and stress score were not significantly different. The result of multivariable logistic regression, analysis showed that the risk of cancer was associated with economic status and marital status, but neither the family function nor the life event stress. Conclusion : In this study, we cannot prove the statistical association between the family function, life event stress and cancer. It is necessary to persevere in our efforts to clarify the relation between stress and disease and to develop the useful tools to measure the Korean family function and life event stress.

• Journal of the Korean Arthroscopy Society
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• v.9 no.2
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• pp.143-147
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• 2005

Purpose: In case of anterior cruciate ligament (ACL) reconstruction, graft tendon is generally fixed in tibial tunnel with knee extended. When reconstructing ACL using hamstring tendon, the authors aim to find out the effect of knee joint position during graft fixation on postoperative knee joint stability and range of motion. Materials and Methods: Prospective study was done on patients who have undergone ACL reconstruction using hamstring tendon from May 2002 to January 2003 We used Rigifix system (Mitek Product, Johnson and Johnson, USA) and Intrafix system for fixation. Thirty nine patients received ACL reconstruction during this period. Excluding 2 patients lost in the follow-up, 37 patients were analyzed. The mean follow-up period was 14 months $(13{\sim}25months)$. Knee position was decided alternatively without any bias. Clinical evaluation was based on Lachman test, pivot shift test, Lysholm score, IKDC(international knee documentation committee) assessment and side to side KT-1000 maximal manual arthrometer difference. Results: After the last follow-up, average postoperative Lysholm score was 93.1 poins(65-98points). According to IKDC score, 26 cases were normal, 10 cases were nearly normal, 1 case was abnormal and we had no case of severe abnormality. The mean difference from the normal side was 2.5 mm under maximal manual loading KT-1000 arthrometer. According to postoperative Lachman test, 32 cases were normal,2 cases were grade I and 1 case was grade II. There were 34 cases of normal, 2 cases of grade I and 1 case of grade II. When using maximal manual KT-1000 arthrometer side to side difference, the difference from the normal side while fixing the tibia at 20'knee flexion was 2.3 mm and at full extention the difference was 2.7 mm. The range of motion at postoperative 1 year showed 5 degree flexion contracture in 1 case at 20 degrees knee flexion and 10 degrees of flexion limitation was observed in 2 cases at full extension. Conclusion: When ACL reconstruction using autogenous hamstring tendon, anterior laxity showed no difference in its stability between two groups. Tibial side fixation at full extension may be helpful in preventing flexion contracture due to overconstrained graft tendon.

• Journal of The Korean Society of Grassland and Forage Science
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• v.19 no.2
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• pp.133-140
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• 1999

This pot experiment was conducted to find out the forage productivity and quality in a grass/clover sward as affected by the application of three different fertilizers; double superphosphate(DS), fused Mg-phosphate(FP), and complex fertilizer(CF), on newly reclaimed hilly soil. This 1st part was concerned with the forage yields, yield components and botanical composition. The results obtained are summarized as follows: 1. The significant differences in the yields(relative yields, %) of whole forages and legume were laid in the following increasing order; CF(relative yield: 150.4% in whole forages and 169.7% in ladino clover) > FP(125.4% in whole forages and 121.7% in ladino clover) > DS(100.0%). The yield of orchardgrass was significantly reduced in the DS plot, compared with the yields in the FP and CF plots, whereas these showed no significant differences between the FP and CF plots. 2. In the botanicl composition, it showed that the rates of grass : legume were 48:52% in the DS and FP, and 40:60% in the CF. It was recognized that the application of complex fertilizer contributed to the increasing of the yields of whole forages, and especially legume yield and rate in the mixed sward.

• Journal of The Korean Society of Grassland and Forage Science
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• v.14 no.4
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• pp.271-280
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• 1994

The aim of this experiment was to investigate the effects of fertilizing mineral nitrogen on dry matter yield of Reed canarygrass and also to estimate proper levels of fertilizing nitrogen when uncultivated rice paddy rapidly increased these days, was used for the production if Reed canarygrass. \ulcornerhe results are as follows. 1. Relative dry matter according to cutting frequency was appeared the highest at the 2nd cut for 3 and 4 cutting frequencies, and the 3rd cut for 5 cutting frequency. Those were 43.1, 34.0 and 34.1 % respectively. 2. When using only phosphrous and potassium, the average dry matter per year and ha was between 9.0 and 12.0 tons(3, 4 and 5 cutting frequency) and the highest dry matter was shown at 5 cutting frequency. 3. In accordance to the increase in the fertilization of nitorgen, the yield of dry matter was increased and, when 30 kg/ha/cut of mineral nitrogen was added, the biggest increase rate per added nitrogen for dry matter yield per year compared to that of no fe~tilization of nitrogen was recorded and it was 2.7, 3.3, and 3.4 tons/ ha for 3, 4 and 5 cutting frequencies respectively. 4. The efficiencies of mineral nitrogen on dry matter yield(DM kg/N kg) were the highest when 30kg nitrogen was applied particularly in 3, 4 and 5 cutting frequencies(29.7, 27.2, 22.8 DM kg/N kg). It recorded the highest of all the treatments. The efficiency was actually decreased in higher application of mineral nitrogen. The total nitrogen yield efficiency was the highest in 30kg(0.45kg and 0.48kg at 4 and 5 cutting frequency) and 60kg fertilization/ha/cut (0.46kg at 3 cuting frequency) and the decreased efficiencies appeared at fertilization of higher nitrogen. 5. Economical borden of mineral nitrogen fertilization were between 199.2 and 243.3kglha at 3 cutting frequency, between 253.4 and 295.9kg at 4 cutting frequency and between 302.2 and 361.3kg at 5 cutting frequency. 6. Under the condition of this experiment, the cutting frequency leading the potential production at maximum was 3 cutting frequency. At 3 cutting frequency, the efficiency of nitrogen utilization was higher and 15 or 16 tons of dry matter was obtained which is a level of economical border at fertilization between 200 and 240kglha. It wrs possible to obtain the maximal dry matter yield(l7 tonslha) at fertilization of lower level than 400kgl ha.

• Advances in pediatric surgery
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• v.16 no.1
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• pp.1-10
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• 2010

The members of the Korean Association of Pediatric Surgeons conducted a retrospective study of two hundred and twenty-two cases of intestinal atresia for the period from January 1, 2007 to December 31, 2009. Seventeen hospitals were involved. There were 76 duodenal, 65 jejunal, and 81 ileal atresias (3 colonic). The male to female ratio was 0.85:1 in DA and 1.34:1 in JIA. Ninety-four patients(43.3 %) were premature babies (DA 40.3 %, JA 64.6 %, IA 28.8 %), and 70 babies (32.0 %) had low birth weight (DA 38.7 %, JA 44.4 %, IA 16.0 %). Antenatal diagnosis was made in 153 cases (68.9 %). However, 27 infants (17.6 %) with antenatal diagnosis were transferred to the pediatric surgeon's hospitals after delivery. Maternal polyhydramnios was observed in 81 cases (36.59 %) and most frequent with proximal obstruction. In forty-four cases (19.8 %), only simple abdominal film was taken for diagnostic study. The associated malformations were more frequently observed in DA - 61.8 % in DA and 22.6 % in JIA. Meconium peritonitis, small bowel volvulus and intussusception were more frequently associated with ileal atresia. The overall mortality rate was 3.6 %. (Abbreviations: DA;duodenal atersia, JA;jejunal atresia, JIA;jejunoileal atresia, IA;ileal atrsia).