• 디지털융복합연구
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• 제14권12호
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• pp.369-375
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• 2016

본 연구는 환자의 경추보호대 착용 여부에 따른 후두마스크기도기(LMA)와 I-gel, Streamlined Liner of the Pharynx Airway(SLIPA) 등 3가지 성문위기구의 삽관 용이성을 비교하기 위해 시행되었다. 응급의료현장에서 활동 중인 119 구급대원 39명에게 3가지 성문위기구에 대한 짧은 교육을 시행한 후 삽관시간과 삽관시도횟수를 측정하였다. 삽관시간은 중립위와 경추보호대 착용 시 모두 I-gel($10.5{\pm}2.2$, $11.4{\pm}5.7$), SLIPA($12.3 {\pm}5.1$, $12.0{\pm}6.8$), LMA($17.2{\pm}3.2$, $18.5{\pm}5.5$) 순으로 빨랐다 (p<0.05). 각 기도기별 중립위와 경추보호대 착용 시 삽관시간의 차이는 없었다. 결론적으로 I-gel과 SLIPA가 LMA보다 중립위와 경추보호대 착용 시 모두에서 삽관시간이 더 빠른 결과를 보였다.

• 한국응급구조학회지
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• 제16권2호
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• pp.23-30
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• 2012

Purpose : This study was designed to compare the easiness and speed of insertion of three supraglottic airway devices(SADs) in a manikin setting. Methods : Three different SADs - Laryngeal Mask Classic(cLMA), I-gel and Streamlined Liner of the Pharynx Airway(SLIPA) were applied. One hundred and nineteen paramedical students with(group H) or without (group L) previous airway experience were taught brief manikin training about the use of the cLMA, I-gel and SLIPA. The students inserted each device in a randomized order. Time to effective ventilation was recorded in seconds from holding the device to the first chest inflation. Success was determined as adequate chest wall movement. Results : The insertion attempts were lesser in I-gel($1.00{\pm}0.00$) and SLIPA($1.05{\pm}0.27$) than cLMA($1.16{\pm}0.41$, p<.05). The shortest time to insertion was recorded for I-gel($10.5{\pm}3.0sec$), followed by the SLIPA($12.9{\pm}4.5sec$) and cLMA($19.6{\pm}4.1sec$, p<.05). There were no significant differences in the insertion attempts and insertion time of I-gel between group L and group H. But in cLMA, longer insertion time and more insertion attempts were recorded in group L than group H. Conclusion : Both I-gel and SLIPA were superior to cLMA in the easiness and speed of insertion. Even in novice students, I-gel showed an excellent result in a manikin.

• 대한응급의학회지
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• 제29권6호
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• pp.578-584
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• 2018

Objective: This study examined the initial partial pressure of carbon dioxide ($PCO_2$) as a possible indicator of prehospital ventilation and its association with prehospital i-gel in out-of-hospital cardiac arrest (OHCA) patients. Methods: The demographics and arrest parameters, including i-gel insertion and initial arterial blood gas analysis, of OHCA patients who visited the emergency department were analyzed retrospectively. Linear regression analysis was performed to examine the association between i-gel insertion and the initial $PCO_2$. Results: A total of 106 patients were investigated. Fifty-six patients had prehospital i-gel insertion and 50 patients did not have a prehospital advanced airway. The initial $PCO_2$ was higher in the i-gel group than the no advanced airway group (105.2 mmHg [77.5-134.9] vs. 87.5 mmHg [56.8-115.3], P=0.03). Prehospital i-gel insertion was associated with a higher initial $PCO_2$ level (${\beta}$ coefficient, 20.3; 95% confidence interval, 2.6-37.9; P=0.03). Conclusion: Prehospital insertion of i-gel was associated with higher initial $PCO_2$ values in OHCA patients compared to no advanced airway.

• Macromolecular Research
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• 제10권6호
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• pp.325-331
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• 2002

Phase behavior of a PEO-PPO-PEO (Pluronic P103) triblock copolymer in water is investigated using small-angle neutron scattering (SANS), small-angle X-ray scattering (SAXS), dynamic light scattering (DLS) and rheology. Pluronic P103 shows apparent two gel states in different temperature regions. The first sol-to-gel transition at a lower temperature (i.e., the hard gel I state) turns out to be the hexagonal microphase as evidenced by the combined SANS and SAXS and the frequency dependence of both G′ and G" in rheology. In contrast to the hard gel I, the second sol-to-gel transition (i. e., the hard gel II state) at a higher temperature represents the block copolymer micelles in somewhat disordered state rather than the ordered state seen in the hard gel I. Moreover, turbidity change depending only on the temperature with four distinct regions is observed and the large aggregates with size larger than 5,000 nm are detected with DLS in the turbid solution region. Based upon the present study, two different gelation mechanisms for aqueous PEO-PPO-PEO triblock copolymer solutions are proposed.

• 폴리머
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• 제38권4호
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• pp.425-433
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• 2014

In this study, microstructure and gel content (C-C) of polybutadiene rubber (PBR) were investigated using various techniques including ASTM D 3616, attenuated total reflectance Fourier transform infrared spectrometry (ATR FTIR), differential scanning calorimetry (DSC) and nuclear magnetic resonance spectroscopy (NMR). The ATR FTIR spectra of the samples were investigated to determine the cis, trans, 1, 2-vinyl and the C-C gel content in PBR. The absorbance ratios of specific peaks in different grades of PBR were correlated with the C-C gel content measured by the ATR FTIR techniques. Physico-mechanical and rheological properties of rubber compounds based on BR with various amounts of gel were determined. The results showed that there is an acceptable correlation between these properties and the C-C gel content of PBR.

• 한국세라믹학회지
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• 제33권12호
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• pp.1394-1402
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• 1996

The Silica gel with the density of 0.2g/cm3 and porosity of 90% was synthesized. The silica wet gel was dried and heat-treated under the ambient pressure after modification of the wet gel surface by TMCS. Specific surface area total pore volume and mean pore radius of dried gel were all increased with increasing heat treatment temperature and confirmed about 1400m2/g, 4.5cc/g and 8 nm respectively after heat treatment above 25$0^{\circ}C$. But the pore size distribution of dried gel was in the range of 1-100nm and was almost indepen-dent of temperature. As the result of external shape pore characteristics and microstructure of gel using SEM similar properties were observed between the silica gel synthesized in this study and the silica aerogel through the super critical drying.

• Journal of Yeungnam Medical Science
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• 제13권1호
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• pp.46-58
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• 1996

세포막 정보전달 과정에 참여하는 효소로 inositol triphosphate($InsP_3$)를 분해하는 $InsP_3$ kinase를 소의 뇌 조직으로 부터 새로운 정제방법을 개발하고 isozyme들의 특성을 관찰하여 다음과 같은 결과를 얻었다. 분쇄한 소의 뇌조직을 PEG로 단백침전하고 DEAE cellulose chromatography 하여 $InsP_3$ kinase I, II의 두 isozyme을 얻었으며, 각각의 isozyme 분획을 Matrix green gel 및 calmodulin-Affigel 15 column으로 chromatography하였다. Phenyl-TSK HPLC하여 정제하였으며 I은 3,103배, II는 2,310 배의 정제를 나타내었다. 정제 단계에서 specific activity를 비교해 볼 때 Matrix green gel chromatography가 DEAE cellulose에서 보다 I이 30배, II가 약 2.3배로 나타났고 정제배수도 I이 17.2%에서 62.1%로 II가 16.6%에서 38%로 나왔으나 calmodulin-Affigel 15과 비교시는 큰 차이가 없었다. 그러므로 Matrix green gel이 정제에서 매우 중요한 단계라 할 수 있다. 효소의 분자량을 알기 위하여 DEAE HPLC로 두 개의 isozyme을 분리하여 전기영동한 결과 I은 환자량 145,000, 85,500 및 69,500이 3개의 단백질을 얻었고 II는 분자량 79,000 및 57,000의 2개의 단백질을 얻었다.

• Bulletin of the Korean Chemical Society
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• 제32권9호
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• pp.3267-3273
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• 2011

Ag(I) carboxylate gelators with mixed-ligands were systemically investigated to understand the mechanism of the organic gel formation. The gelators constructed 3-D networks of nanometer-sized thin fibers which facilitated gel formation in various aromatic organic solvents, even at very low concentrations. The loss of reflection peaks in the X-ray diffraction data indicated the reduction of strong interactions between the long alkyl chains as the Ag(I) carboxylates formed gels by maximizing their interactions with the organic solvents. The gelation temperature ($T_{gel}$) was measured to explore the interaction between the gelator molecules and solvents depending on their composition and concentration. Based on the gelation phenomena, a dissociation/re-association mechanism was proposed.

• 미생물학회지
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• 제23권1호
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• pp.13-19
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• 1985

제한효소 Acc I을 정제하고 그 효소적 특성을 연구하였다. 300g(wet weight)의 Acinetobacter calcoaceticus 로부터 얻은 crude extract를 sample로 하여 ammonium sulfate fractionation을 거쳐 Heparin-agarose, DEAE-se-phades, Affi,-gel Blue, phosphoceIIulose, hydroxylapatite의 순서로 chromatography를 수행한 결고 0 .28mg의 AccI 제한효소를 얻었다. 효소의 specific activity는 mg당 $1.1{\times}10^{s}$ unit 이었다. 정제된 Acc [제한효소는 10% SDS-polyacrylamide gel electrophoresis에서 한개의 band로 나타났으며 그 분자량은 45,000~1,000이었다. 이 효소는 $MgCl_2$ 존재하에, pH 8.0에서 11.0사이에서 최대의 활성을 보였다. NaCl은 이 효소의 활성에는 필요하지 않았으나 150mN이상에서는 급격한 효소 활성의 감소가 있었다.

• 치위생과학회지
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• 제10권5호
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• pp.373-378
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• 2010

불소도포와 치면열구전색은 치아우식을 예방하기 위한 목적으로 임상에서 널리 병용하여 사용되고 있지만, 불소가 치면열구전색제의 표면 구조를 변화시켜 미생물이 서식할 조건을 마련하여 수복물의 수명을 단축시키는 원인이 될 수 있다. 이에 본 연구에서는 현재 치과 임상에서 많이 사용되고 있는 레진계 실란트 Concise와 Eco-S를 사용하였고, 대표적인 불소도포제재 1.23% APF gel과 5% NaF Fluoride Varnish가 치면열구전색제의 표면 구조에 미치는 영향을 평가하기 위해 제작된 치면열구전색제시편을 각각 5군으로 불소제재를 처리하지 않은 I군, APF gel 1분간 처리한 II군, APF gel 4분간 처리한 III군, Fluoride Varnish 1분간 처리한 IV군, Fluoride Varnish 4분간 처리한 V군으로 분류하여 마모실험에 의한 무게변화를 측정하였고, 광학현미경을 이용하여 표면구조를 관찰하여 다음과 같은 결론을 얻었다. 1. 치면열구전색제 Concise를 이용한 마모실험에서 불소제재를 처리하지 않은 I군에 비하여 APF gel 4분간 처리한 III군에 무게 감소가 증가하였으며, Fluoride Varnish 4분간 처리한 V군에서 무게 감소가 적으며(p<0.05), Eco-S를 이용한 마모실험 결과 또한 같았다(p<0.05). 2. 광학현미경으로 표면의 변화를 관찰한 결과 APF gel을 도포한 경우 기질의 소실로 필러가 두드러진 양상을 보였으며, 각 군 별로는 APF gel 4분간 처리한 III군, APF gel 1분간 처리한 II군, 불소제재를 처리하지 않은 I군, Fluoride Varnish 1분간 처리한 IV군, Fluoride Varnish 4분간 처리한 Ⅴ군의 순으로 표면 거칠기가 감소되는 결과를 보였다. 결론적으로, 치면열구전색과 불소도포를 당일 시행하는 경우, 불소도포제를 1.23% APF gel 사용 시 4분 보다 1분 도포하며, 1.23% APF gel보다는 5% NaF Fluoride Varnish 도포하는 것이 치면열구전색제의 표면 구조에 영향을 줄일 수 있다고 사료된다.