• Title/Summary/Keyword: I-function

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Effects of Self-stretching and Joint Mobilization to Upper Thoracic Vertebrae in Craniovertebral Angle and Autonomic System Function in Chronic Cervical Pain (만성 목통증에 대한 자가신장과 위등뼈 관절가동술이 머리척추각 및 자율신경계 기능에 미치는 효과)

  • Nam, Ki-Won;Kim, Se-Hun;Seo, Dong-Yel
    • Journal of the Korean Society of Physical Medicine
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    • v.13 no.2
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    • pp.61-68
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    • 2018
  • PURPOSE: This study aimed to examine the effects of self-stretching (SS) and joint mobilization (JM) on pain, craniovertebral angle (CVA), autonomic system function in chronic cervical pain patient with forward head posture (FHP). METHODS: A total of 30 male college students were selected as study subjects, and were divided into Group I (general physical therapy; GPT, n=10), Group II (GPT+SS, n=10), Group III (GPT+JM, n=10). All groups were evaluated three times a week for 4 weeks. Pain was measured by visual analogue scale (VAS), CVA was measured using digital goniometer and autonomic system function (heart rate; HR, skin conductivity; SC, LF norm, HF norm, LF/HF ratio) was measured by Biofeedback ProComp Infiniti. After 4 weeks, paired t-test was used to compare the changes within the group and one way ANOVA was used to compare those between the groups. RESULTS: In Group I, VAS was significantly decreased. In Group II and III was a significantly change in all items. In comparison between Group I and II was a difference in all items except HR. In comparison between Group I and III was a difference in all items. In comparison between Group II and III was a difference in VAS, LF norm and LF/HF ratio. CONCLUSION: This study showed that SS and JM can effectively reduce pain and normalize the autonomic system function.

The Effects of Dual Task Training According to Variability of Walking Environment on Balance, Gait and Function of Stroke Patients (보행환경 가변성에 따른 이중과제 훈련이 뇌졸중 환자의 균형, 보행 및 기능에 미치는 영향)

  • Kim, Su-Jin;Lee, Hyo-Jeong
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.2
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    • pp.23-33
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    • 2021
  • Purpose : This study aimed to investigate the effects of dual-task training according to the variability of the walking environment on balance, gait, and function in patients with stroke. Methods : Twenty-five patients with stroke were randomly assigned to experimental group I (n=12) and experimental group II (n=13). Experimental group I and II performed obstacle and non-obstacle walking training, respectively, along with cognitive tasks for 21 minutes per session, 3 times a week for 6 weeks. Both groups received additional general physical therapy for 30 minutes per session. The functional reach test (FRT), gait analyzer (G-Walk), and functional independence measure (FIM) were used to evaluate balance, gait and function of pre- and post-interventions, respectively, while gait cadence, gait velocity, and stride length were evaluated using a gait analyzer. Results : In the within-group comparison of FRT, all the two groups showed significant post-intervention improvements (p<.05). In within-group comparison of gait cadence, all the two groups showed significant post-intervention improvements (p<.05). In within-group comparison of gait velocity, all the two groups showed significant post-intervention improvements (p<.05). In within-group comparison of stride length, experimental group I showed significant post-intervention improvements (p<.05), while experimental group II did not show significant post-intervention improvements (p>.05). In within-group comparison of FIM scores, experimental group I showed significant post-intervention improvements (p<.05), while experimental group II did not show significant post-intervention improvements (p>.05). There was a significant difference in the change of FIM scores pre- and post-intervention (p<.05) in the between-group comparison. Conclusion : The results of this study show that dual-task training with cognitive tasks and walking training can improve the balance, gait and function of patients with stroke, and obstacle walking training is effective for improving functions including activities of daily living compared to non-obstacle walking training.

Differential Effects of Typical and Atypical Neuroleptics on Mitochondrial Function In Vitro

  • Josephine, S.;Napolitano, Modica;Lagace, Christopher-J.;Brennan, William-A.;Aprille, June-R.
    • Archives of Pharmacal Research
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    • v.26 no.11
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    • pp.951-959
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    • 2003
  • A series of typical (chlorpromazine, haloperidol and thioridazine) and atypical (risperidone, quetiapine, clozapine and olanzapine) antipsychotics were tested for effects on integrated bioenergetic functions of isolated rat liver mitochondria. Polarographic measurement of oxygen consumption in freshly isolated mitochondria showed that electron transfer activity at respiratory complex I is inhibited by chlorpromazine, haloperidol, risperidone, and quetiapine, but not by clozapine, olanzapine, or thioridazine. Chlorpromazine and thioridazine act as modest uncouplers of oxidative phosphorylation. The typical neuroleptics inhibited NADH-coenzyme Q reductase in freeze-thawed mitochondria, which is a direct measure of complex I enzyme activity. The inhibition of NADH-coenzyme Q reductase activity by the atypicals risperidone and quetiapine was 2-4 fold less than that for the typical neuroleptics. Clozapine and olanzapine had only slight effects on NADH-coenzyme Q reductase activity, even at 200 $\mu$ M. The relative potencies of these neuroleptic drugs as inhibitors of mitochondrial bioenergetic function is similar to their relative potencies as risk factors in the reported incidence of extrapyramidal symptoms, including tardive dyskinesia (TD). This suggests that compromised bioenergetic function may be involved in the cellular pathology underlying TD.

A Swap Optimization for Dynamic Economic Dispatch Problem with Non-smooth Function (비평활 발전비용함수를 가진 동적 경제급전문제의 교환 최적화)

  • Lee, Sang-Un
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.11
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    • pp.189-196
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    • 2012
  • This paper proposes Swap algorithm for solving Dynamic Economic Dispatch (DED) problem. The proposed algorithm initially balances total load demand $P_d$ with total generation ${\Sigma}P_i$ by deactivating a generator with the highest unit generation cost $C_i^{max}/P_i^{max}$. It then swaps generation level $P_i=P_i{\pm}{\Delta}$, (${\Delta}$=1.0, 0.1, 0.01, 0.001) for $P_i=P_i-{\Delta}$, $P_j=P_j+{\Delta}$ provided that $_{max}[F(P_i)-F(P_i-{\Delta})]$ > $_{min}[F(P_j+{\Delta})-F(P_j)]$, $i{\neq}j$. This new algorithm is applied and tested to the experimental data of Dynamic Economic Dispatch problem, demonstrating a considerable reduction in the prevalent heuristic algorithm's optimal generation cost and in the maximization of economic profit.

Cloning and Characterization of cDNA for Korean Rockfish (Sebastes schlegeli ) Insulin-like Growth Factor-I

  • Kwon, Mi-Jin;Jo, Jae-Yoon;Nam, Taek-Jeong
    • Journal of Marine Bioscience and Biotechnology
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    • v.1 no.2
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    • pp.119-125
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    • 2006
  • To understand the comprehensive mechanisms of biological function for insulin-like growth factor-I (IGF-I) in vertebrates, we have investigated the cDNA sequence of this gene in the korean rockfish (Sebastes schlegeli). The mature form of korean rockfish IGF-I was found to be comprised of 67 amino acid residues, showing about a 7 kDa molecular weight. In this study, we used the polymerase chain reaction (PCR) to obtain a korean rockfish IGF-I (KR IGF-I) cDNA fragment, and methods of rapid amplification of cDNA ends (RACE) to obtain a full length of the KR IGF-I sequence. The KR IGF-I encoded for a predicted amino acid sequence showed identities of 93.6 %, 90.7 %, and 85.4 % in comparison with flounder, chinook salmon, and human IGF-I, respectively. To obtain recombinant biologically active polypeptides, korean rockfish B-C-A-D domains were amplified using the PCR, then the isolated cDNA was expressed in the E. coli BL21(DE3). The recombinant KR IGF-I protein biological function was measured by stimulation of [$^3H$] thymidine incorporation, suggesting the cDNA codes for the korean rockfish proIGF-I.

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Error Intensity Function Models for ML Estimation of Signal Parameter, Part I : Model Derivation (신호 파라미터의 ML 추정기법에 대한 에러 밀도 함수 모델에 관한 연구 I : 모델 정립)

  • Joong Kyu Kim
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.30B no.12
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    • pp.1-11
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    • 1993
  • This paper concentrates on models useful for analyzing the error performance of ML(Maximum Likelihood) estimators of a single unknown signal parameter: that is the error intensity model. We first develop the point process representation for the estimation error and the conditional distribution of the estimator as well as the distribution of error candidate point process. Then the error intensity function is defined as the probability dessity of the estimate and the general form of the error intensity function is derived. We then develop several intensity models depending on the way we choose the candidate error locations. For each case, we compute the explicit form of the intensity function and discuss the trade-off among models as well as the extendability to the case of multiple parameter estimation.

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Development of Algorithms for Sorting Peeled Garlic Using Machnie Vison (I) - Comparison of sorting accuracy between Bayes discriminant function and neural network - (기계시각을 이용한 박피 마늘 선별 알고리즘 개발 (I) - 베이즈 판별함수와 신경회로망에 의한 설별 정확도 비교 -)

  • 이상엽;이수희;노상하;배영환
    • Journal of Biosystems Engineering
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    • v.24 no.4
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    • pp.325-334
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    • 1999
  • The aim of this study was to present a groundwork for development of a sorting system of peeled garlics using machine vision. Images of various garlic samples such as sound, partially defective, discolored, rotten and un-peeled were obtained with a B/W machine vision system. Sorting factors which were based on normalized histogram and statistical analysis(STEPDISC Method) had good separability for various garlic samples. Bayes discriminant function and neural network sorting algorithms were developed with the sample images and were experimented on various garlic samples. It was showed that garlic samples could be classified by sorting algorithm with average sorting accuracies of 88.4% by Bayes discriminant function and 93.2% by neural network.

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A Study on Prediction of Die Life of Warm Forging by Wear(I) -Construction of Die Wear Model- (마멸에 의한 온간단조의 금형수명 예측에 관한 연구(I) -금형 마멸 모델의 정립-)

  • 강종훈;박인우;제진수;강성수
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 1998.03a
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    • pp.88-93
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    • 1998
  • The service life of tools in metal forming process is to a large extent limited by wear, fatigue fracture and plastic deformation. In warm forging processes wear is the predominant factor for operating lives of tools. To predict tool life by wear, Archard's wear model is generally applied. Usually hardness of die is considered to be a function of temperature in Archard's wear model. But hardness of die is a function of not only temperature but also operating time of die. To consider softening of die by repeated operations, it is necessary to express hardness of dies by a function of temperatures and operating time. By experiment of reheating of dies, die softening curves were obtained. Finally modified Archard's wear model in which hardness of die was expressed as a function of main tempering curve was proposed.

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A Study on the Reliability of Ru-Zr Metal Gate with Thin Gate Oxide (박막 게이트 산화막에 대한 Ru-Zr 금속 게이트의 신뢰성에 관한 연구)

  • 이충근;서현상;홍신남
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.53 no.4
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    • pp.208-212
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    • 2004
  • In this paper, the characteristics of co-sputtered Ru-Zr metal alloy as gate electrode of MOS capacitors have been investigated. The atomic compositions of alloy were varied by using the combinations of relative sputtering power of Ru and .Zr. C-V and I-Vcharacteristics of MOS capacitors were measured to find the effective oxide thickness and work function. The alloy made of about 50% of Ru and 50% of Zr exhibited an adequate work function for nMOS. C-V and I-V measurements after 600 and $700^{\circ}C$ rapid thermal annealing were performed to prove the thermal and chemical stability of the Ru-Zr alloy film. Negligible changes in the accumulated capacitance and work function before and after annealing were observed. Sheet resistance of Ru-Zr alloy was lower than that of poly-silicon. It can be concluded that the Ru-Zr alloy can be a possible substitute for the poly-silicon used as a gate of nMOS.

ON THE GENOTYPE FREQUENCIES AND GENERATING FUNCTION FOR FREQUENCIES IN A DYPLOID MODEL

  • Choi, Won
    • Korean Journal of Mathematics
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    • v.29 no.1
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    • pp.75-80
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    • 2021
  • For a locus with two alleles (IA and IB), the frequencies of the alleles are represented by $$p=f(I^A)={\frac{2N_{AA}+N_{AB}}{2N} },\;q=f(I^B)={\frac{2N_{BB}+N_{AB}}{2N}}$$ where NAA, NAB and NBB are the numbers of IA IA, IA IB and IB IB respectively and N is the total number of populations. The frequencies of the genotypes expected are calculated by using p2, 2pq and q2. So in this paper, we consider the method of whether some genotypes is in Hardy-Weinburg equilibrium. Also we calculate the probability generating function for the offspring number of genotype produced by a mating of the ith male and jth female under a diploid model of N population with N1 males and N2 females. Finally, we have conditional joint probability generating function of genotype frequencies.