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Respiratory Severity Score as a Predictive Factor for the Mortality of Congenital Diaphragmatic Hernia

  • Ahn, Ja-Hye;Jung, Young Hwa;Shin, Seung Han;Kim, Hyun-Young;Kim, Ee-Kyung;Kim, Han-Suk
    • Neonatal Medicine
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    • v.25 no.3
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    • pp.102-108
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    • 2018
  • Purpose: Congenital diaphragmatic hernia (CDH) is rare but potentially fatal. The overall outcome is highly variable. This study aimed to identify a simple and dynamic parameter that helps predict the mortality of CDH patients in real time, without invasive tests. Methods: We conducted a retrospective chart review of 59 CDH cases. Maternal and fetal information included the gestational age at diagnosis, site of defect, presence of liver herniation, and lung-to-head ratio (LHR) at 20 to 29 weeks of gestational age. Information regarding postnatal treatment, including the number of days until surgery, the need for inhaled nitric oxide (iNO), the need for extracorporeal membrane oxygenation (ECMO), and survival, was collected. The highest respiratory severity score (RSS) within 24 hours after birth was also calculated. Results: Statistical analysis showed that a younger gestational age at the initial diagnosis (P<0.001), a lower LHR (P=0.001), and the presence of liver herniation (P=0.003) were prenatal risk factors for CDH mortality. The RSS and use of iNO and ECMO were significant factors affecting survival. In the multivariate analysis, the only remaining significant risk factor was the highest preoperative RSS within 24 hours after birth (P=0.002). The area under the receiver operating characteristic curve was 0.9375, with a sensitivity of 91.67% and specificity of 83.87% at the RSS cut-off value of 5.2. The positive and negative predictive values were 82.14% and 92.86%, respectively. Conclusion: Using the RSS as a prognostic predictor with simple calculations will help clinicians plan CDH management.

Design of Pultruded I-shape FRP Compression Member (펄트루젼 I형 FRP 압축재의 설계)

  • Joo, Hyung-Joong;Lee, Seung-Sik;Yi, Jong-Seok;Yoon, Soon-Jong
    • Composites Research
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    • v.25 no.2
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    • pp.46-53
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    • 2012
  • Using pultrusion process, FRP composite structural members having various cross-section shapes can be produced with unlimited lengths. Because of such reasons, these members are suitable for the application in the construction field. Especially, this material is highly appreciated if the material is to be used in the corrosive environments such as aquatic or oceanic environments due to its high corrosion resistance. However, design criteria for the FRP structural member are not developed yet. So, the research on the development of design guideline is needed ungently. In order to use the pultruded structural FRP member efficiently, the members are composed of thin plate components, and thus, the member is prone to buckle easily and the buckling is one of the governing strength limit states for the design. In this paper, we present the analytical study results pertaining to the buckling behavior of I-shape FRP compression member. In addition, design procedure and flow-chart are also proposed based on the study results including previous experimental results. Proposed design procedure is similar to that in ANSI/AISC 360-10 with minor modification. Therefore, it is convinced that the structural design of pultruded FRP compression member could be done easily by following design procedure proposed in this paper.

PREVALENCE AND SEVERITY OF MALOCCLUSION IN CHILDREN 13 TO 15 YEARS OF AGE LIVING IN SEOUL (서울시내에 거주하는 13세-15세 청소년들의 부정교합에 관한 역학적 연구)

  • Song, Kyung-Won;Kim, Jin-Tae
    • Journal of the korean academy of Pediatric Dentistry
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    • v.11 no.1
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    • pp.121-130
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    • 1984
  • Childrens between the ages of 13 and 15 years, living in Seoul, were examined in order to determine the prevalence and severity of malocclusion in the permanent dentition. This survey encompassed 981 children and an individual chart was prepared for each subject recording an original HMAR score and classification of occlusion according to Angle. Also, subjective evaluation of "treatment needs" was carried out in 581 children. The results were as follows: 1. Of the 981 children in this survey, 12,1 percent showed excellent occlusion. (0 point) 2. The 14 percent of the children who had a score of 24 and above all appeared to belong to the "treatment highly desirable" or "treatment mandatory" category. 3. The incorporation of SAR (Supplementary Assessment Record) into the HMAR can provide more sensitive method for evaluating severity of malocclusion. 4. According to Angle's classification 77.4 percent of all malocclusion belonged to Class I, 1.3 percent to Class II, Division 1, 0.9 percent to Class II, Division 2, and 11.3 percent to Class III. 5. The mean HMAR score for Class I was significantly lower than for either Class II, Division 1 or Class III. (P < 0.05) 6. A close relationship was found between the degree of "treatment needs" and the value obtained by the HMAR scoring. (chi-square test, p < 0.05) The differences between the mean HMAR scores of the various subjectively defined categories were statistically significant. (P < 0.001)

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Teucrium polium L. Improved Heart Function and Inhibited Myocardial Apoptosis in Isolated Rat Heart Following Ischemia-Reperfusion Injury

  • Mahmoudabady, Maryam;Talebian, Faezeh Sadat;Zabihi, Narges Amel;Rezaee, Seyed Abdolrahim;Niazmand, Saeed
    • Journal of Pharmacopuncture
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    • v.21 no.3
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    • pp.159-167
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    • 2018
  • Objectives: Myocardial reperfusion is the only logical cure for ischemic heart disease. However, ischemic-reperfusion (I/R) injury is one of the underlying factors facilitating and accelerating the apoptosis in the myocardium. This study set to investigate the impact of Teucrium polium (TP) hydro-alcoholic extract on I/R induced apoptosis in the isolated rat heart. Methods: Isolated rat hearts were classified into six groups. The control samples were subjected to 80 min of perfusion with Krebs-Henseleit bicarbonate (KHB) buffer; in control-ischemia group, after primary perfusion (20 min) the hearts were exposed to global ischemia (20 min) and reperfusion (40 min). Pretreated groups were perfused with $500{\mu}M$ of vitamin C and various TP concentrations (0.5, 1, 2 mg/ml) for 20 min, and then the hearts were exposed to ischemia and reperfusion for 20 min and 40 min, respectively. Cardiodynamic parameters including rate pressure product (RPP), heart rate (HR), the maximum up/down rate of left ventricular pressure (${\pm}dp/dt$), left ventricular developed pressure (LVDP), and coronary artery flow (CF) were achieved from Lab Chart software data. The Bax and BCl-2 gene expressions were measured in heart samples. Results: Hearts treated with TP extract and vit C represented a meaningful improvement in cardiac contractile function and CF. The overexpression of Bcl-2, downregulation of Bax, and improvement of apoptotic index (Bax/Bcl-2) were observed in pretreated TP extract and vit C hearts. Conclusion: The TP extract was found to ameliorate the cardiac function in the reperfused myocardium. Also, it can hinder apoptotic pathways causing cardioprotection.

Interstitial Radium Implantation and Cobalt-60 Irradiation of the Tongue Cancer (IbidI) (설암의 조직간내 라디움치료에 관하여)

  • 안경성;박주방;윤용규
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1972.03a
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    • pp.16.1-16
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    • 1972
  • In 1971 there were 5 cases of the tongue cancer in stage I & II treated concomitantly with interstitial radium implantation and Cobalt-60 irradiation at the Yonsei University Hospital Cancer Center. This is the interim report of the course of the primary site of those treated cases.

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Analysis of Resonant Slots in the Narrow Wall of a Rectangular Waveguide (구형 도파관 측벽 공진 슬랏의 특성 해석)

  • 박정호;김민준
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.3 no.1
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    • pp.23-28
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    • 1999
  • Rectangular waveguide slot antenna which has simple structure, high efficiency, high trust and small size, is extending in a field of application such as many Radar and Microwave communication. A slot cut into a wall of waveguide is propagated electromagnetic wave to free space it interrtupts the flow of current inner conductor of waveguide. Therefore incident of slot, cutdepth, width, length, i.e. are important parameter of characteristic change of the slot antenna. Result from difficulty of theoretical analysis about slot frequently experimental measured data useful design and manufacture have been accomplished. In this paper, we find the suitable method of analysis that compare two analysis results with measured result of established literature - admittance of slot be solved by propagated power from electric field distribution of slot and mode current computation and accomplishment of computable chart which hasresonant length and cutdepth, incident of slot, i.e. and use the HFSS which applyed finite-element method obtain equal slot analyed method.

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Development of a Baseline Setting Model Based on Time Series Structural Changes for Priority Assessment in the Korea Risk Information Surveillance System (K-RISS) (식·의약 위해 감시체계(K-RISS)의 우선순위 평가를 위한 시계열 구조변화 기반 기준선 설정 모델 개발)

  • Hyun Joung Jin;Seong-yoon Heo;Hunjoo Lee;Boyoun Jang
    • Journal of Environmental Health Sciences
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    • v.50 no.2
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    • pp.125-137
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    • 2024
  • Background: The Korea Risk Information Surveillance System (K-RISS) was developed to enable the early detection of food and drug safety-related issues. Its goal is to deliver real-time risk indicators generated from ongoing food and drug risk monitoring. However, the existing K-RISS system suffers under several limitations. Objectives: This study aims to augment K-RISS with more detailed indicators and establish a severity standard that takes into account structural changes in the daily time series of K-RISS values. Methods: First, a Delphi survey was conducted to derive the required weights. Second, a control chart, commonly used in statistical process controls, was utilized to detect outliers and establish caution, attention, and serious levels for K-RISS values. Furthermore, Bai and Perron's method was employed to determine structural changes in K-RISS time series. Results: The study incorporated 'closeness to life' and 'sustainability' indicators into K-RISS. It obtained the necessary weights through a survey of experts for integrating variables, combining indicators by data source, and aggregating sub K-RISS values. We defined caution, attention, and serious levels for both average and maximum values of daily K-RISS. Furthermore, when structural changes were detected, leading to significant variations in daily K-RISS values according to different periods, the study systematically verified these changes and derived respective severity levels for each period. Conclusions: This study enhances the existing K-RISS system and introduces more advanced indicators. K-RISS is now more comprehensively equipped to serve as a risk warning index. The study has paved the way for an objective determination of whether the food safety risk index surpasses predefined thresholds through the application of severity levels.

Mechanical Anisotropy of Pocheon Granite under Uniaxial Compression (일축압축하에서 포천화강암의 역학적 이방성)

  • Park Deok-Won
    • The Journal of Engineering Geology
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    • v.15 no.3
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    • pp.337-348
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    • 2005
  • Jurassic granite from Pocheon area were tested to investigate the effect of microcracks on mechanical properties of the granite. Three oriented core specimens were used for uniaxial compressive tests and each core specimen are perpendicular to the axes'R'(rift plane),'c'(grain plane) and'H'(hardway plane), respectively Among vacious elastic constants, the variation of Poisson's ratio as function of the directions was examined. From the related chart between ratio of failure strength and Poisson's ratio, H-specimen shows the highest range in Poisson's ratio and Poisson's ratio decreases in the order of C-specimen and R-specimen. The curve pattern is nearly linear in stage $I\simIII$ but the slope increases abruptly in stage H-3. As shown in the related chart, diverging point of a curve is formed when ratio of failure strength is $0.92\sim0.96$ Stage IV -3 is out of elastic region. The behaviour of rock in the four fracturing stages was analyzed in term of the stress-volumetric strain me. From the stress increment-volumetric strain equations governing the behaviour of rock, characteristic material constants, a, n, Q, m and $\varepsilon_v^{mcf}$, were determined. Among these, inherent microcrack porosity$(a, 10^{-3})$ and compaction exponent(n) in the microcrack closure region(stage I ) show an order of $a^R(3.82)>a^G(3.38)>a^H(2.32)\;and\;n^R(3.69)>n^G(2.79)>n^H(1.99)4, respectively. Especially, critical volumetric microcrack strain($\varepsilon_v^{mcf}$) in the stage W is highest in the H-specimen, normal to the hardway plane. These results indicate a strong correlation between two major sets of microcracks and mechanical properties such as Poisson's ratio and material constants. Correlation of strength anisotropy with microcrack orientation can have important application in rock fracture studies.

Correlation between BMI and Physical Fitness of College Women in Seoul

  • Na, Hye-Bok;Kim, Hyun-Jung;Park, Kyung-Soon
    • Journal of Community Nutrition
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    • v.5 no.1
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    • pp.29-36
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    • 2003
  • This study investigated the correlation of the physical measurements and the basic physical fitness of 158 female students in the city of Seoul. The average age of the subjects was 22.0 ${\pm}$ 0.13 years old, the average height was 160.9 ${\pm}$ 0.7cm and the average weight was 53.4 ${\pm}$ 0.6kg. The mean BMI (Body Mass Index) was 20.7 ${\pm}$ 0.2kg/㎡. The average muscle mass was 36.5 ${\pm}$ 0.3 and the average body fat percentage was 28.0 ${\pm}$ 0.4%. The basic fitness levels of the subjects were measured based on the evaluation chart of the Korea Health and Science Research Institution (1994). The subjects were divided into 3 groups based on BMI(Group I : BMI < 20, Group II : 20 $\leq$ BMI < 25, Group III BMI $\geq$ 25) and the correlation between BMI and physical fitness was assessed. 1) The muscle strength of the subjects was measured by their grip strength, among other tests. Groups 1 and 2 were evaluated as “su” (level 1) and group 3 was “woo” (level 2). 2) Endurance 1 was tested by push-ups, and while groups 1 and 2 were evaluated as “su” (level 1), group 3 was “ga” (level 5). This result did not suggest any significant relevance among the subjects. 3) Endurance 2 was tested by sit-ups : groups 1 and 2 were evaluated as “mi” (level 3) and group 3 as “yang” (level 4). Group 2 and group 3 showed a significant difference. 4) Instant power was tested by standing high jumps, and although there was a significant difference between group 1 and group 3, all of the subjects were evaluated as “ga” (level 5). 5) Flexibility was measured by how far the subjects could bend forward. There was no significant relevance between the groups and they were all respectively evaluated as “woo” (level 2). 6) Agility was tested with side-steps and all the subjects showed poor agility as “yang” (level 4). 7) Heart and lung endurance was tested by the step test, calculating the maximum oxygen intake with the Physical Energy Index (PEI) and using the numbers according to the evaluation chart. Group 1 was evaluated as “mi” (level 3) and groups 2 and 3 were “woo” (level 2). From these results, we could see the group III (obese group) had a tendency of lower levels in all the variables related to body fitness They showed significantly lower endurance assessed with time for sit-ups and instant power by the standing high jumps. (J Community Nutrition 5(1) : 29∼36, 2003)

The Estimation of Patient's Waiting-Time Using Parking Time (주차시간을 이용한 외래환자 대기시간 추정)

  • Song, Jung-Hup
    • Quality Improvement in Health Care
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    • v.2 no.2
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    • pp.20-30
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    • 1996
  • Background : Theoretically as the waiting-time of patient is estimated in queueing, many men and much money are needed. But being the estimation of patient s waiting-time very important in hospital service, so the continuous monitoring of waiting-time is inevitable. To verify that the estimation of waiting-time using parking time is economical, effective and continuous monitoring method and to develop utilizing the method, this study was done. Method : In parking confirmation office, the personnel of parking office wrote parking confirm time, chart number and whether medical examination and treatment finish or not in parking ticket. The next day the parking tickets were gathered and the above data were input. The input parking data were connected with the hospital outpatient file indexing chart number. Then the patient' s data for department, new patient or not, reservation or not, receipt time and payment time were retrieved. The group for finishing medical treatment were compared with that for not finishing in average time lag between confirmation and out-time for hospital. And In-time for hospital, receipt time, payment and out-time for hospital were also analyzed. Result : Confirming parking ticket, the group for finished medical treatment left hospital after 7 minutes. This result showed that the patient for finished medical treatment left hospital immediately. So parking time was reasonable to estimation of hospital-time was concluded. The time for medical treatment, diagnosis and test was constant for all patients and short for waiting time, Then I concluded that the parking time was reasonable for estimation patient's waiting time. Overall patient's waiting time was 113 minutes and new patient's time was 149 minutes, old patient's times was 109 minutes. Waiting time for reservation patient was 98 minutes and for non reservation patient was 122 minutes. The time from hospital arrival to payment was 50 minutes for the group of reservation patient and 69 minutes for non-reservation group. The time from payment to hospital leaving was 51 minutes and 56 minutes for non reservation group. The short time difference between reserved group and not reserved group from payment to hospital leaving time was due to bottle neck effect. Conclusion : The estimation of patient's waiting time using parking time was reasonable because the possession of car was common and the time for medical treatment was equal and the patient after treatment left hospital immediately. Using this method, timely, fast evaluation and continuous monitoring of the intervention effect were possible.

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