• 지역사회간호학회지
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• 제32권3호
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• pp.303-311
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• 2021

Purpose: This study investigated the health literacy level of, the hypertension knowledge of, the self-management behaviors of, and the factors influencing self-management behaviors of the hypertensive elderly population residing in the urban and rural areas. Methods: Data were collected from November to December 2017 by the trained research staff. For two months, a total of 160 subjects in urban and rural areas who had been taking antihypertensive medications consented to participate in the project. 157 participants completed the survey. Results: The health literacy score of the hypertensive elderly subjects was at 48.38±8.13, the hypertension knowledge score at 8.90±2.01 points, and the self-management behaviors score at 52.96±8.08. The factor that influenced the self-management behaviors of the hypertensive elderly subjects the most was the health literacy, followed by the residential area, and the hypertension knowledge. Conclusion: The research findings suggest that a health promotion program for the hypertensive elderly population should be designed in consideration of the health literacy, the area of residence and the hypertension knowledge of the elderly.

• 한방비만학회지
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• 제23권2호
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• pp.86-97
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• 2023

Objectives: The purpose of this study is to review clinical studies related to the effect of Traditional Chinese Medicine (TCM) on moderate to severe obese patients with hypertension. Methods: Clinical studies from the China National Knowledge Infrastructure (CNKI) were searched by specific keywords and criteria. Total of 7 randomized controlled trials were selected and analyzed. Results: Various evaluation methods were used to see the effect of TCM compared to conventional western medicine. Most of the studies used herbal medicine combined with conventional anti-hypertensive western medicine. The effective rate of anti-hypertension was higher when TCM was added to conventional anti-hypertensive medicine. Traditional medicine treatment showed significant effect on lowering blood pressure and body mass index. Conclusions: Based on the results of the clinical studies from China, TCM can be a valuable option for moderate to severe obese patients with hypertension. Applying Traditional medicine has a significant effect on lowering blood pressure and weight loss. Combining herbal medicine can be worthy of clinical promotion and application for moderate and severe obese patients with hypertension.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2005년도 제57차 추계 학술대회 연제집
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• pp.442-442
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• 2005

• 한국임상수의학회지
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• 제24권4호
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• pp.613-617
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• 2007

중성화된 1년령 말티즈 개(2.4kg)가 간헐적인 기침, 호흡곤란, 운동 불내성을 주요 증상으로 내원하였다. 신체검사 시 제 2음 모순 분열, 확장기 역류성 잡음이 관찰되었으며, 심장초음파에서 주폐동맥의 확장, 심실 중격 비대를 동반한 우심실 편심성 비대, 심각한 삼첨판 역류증과 폐동맥 역류증(5.4m/sec, 3.4m/sec)이 관찰되었다. 이러한 진단 검사 결과를 바탕으로, 본 증례를 선천성 심장 내 단락, 폐쇄성 폐질환, 그리고 우심계의 압력 과부하 또는 폐혈관계과관류와 관련된 전신질환과 감별하여 원발성 폐동맥 고혈압증으로 잠정진단 하였다. 환자는 furosemide와 aspirin을 투여하여, 산소요법을 실시하였다. 본 증례는 드물게 발생하는 개의 원발성 폐동맥 고혈압이다.

• 동의생리병리학회지
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• 제20권1호
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• pp.181-186
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• 2006

A pharmacological inhibition of nitric oxide synthase (NOS) in rats produces vasoconstriction, renal dysfunction, and hypertension. The present study was aimed at investigating whether the methanol extract of Serous commixta cortex (MSC) ameliorates $N^G$-nitro-L-arginine methylester (L-NAME) induced hypertension in rats. Treatment of rats with L-NAME (10 mg/kg/day in drinking water, 5 weeks) caused a sustained increase in systolic blood pressure (SBP). Administration of MSC (100 or 200 mg/kg/day, p.o) significantly lowered the SBP in the L-NAME-treated rats and this effect was maintained throughout the whole experimental period. Moreover, ecNOS expression in aorta and kidney tissue from L-NAME treated rats was significantly restored dy administration of MSC. Furthermore, the impairment of acetylcholine (ACh)-induced relaxation of aortic rings in the L-NAME treated rats was reversed dy administering of MSC. The renal functional parameters including urinary volume, sodium excretion, and creatinine clearance (Ccr) were also restored by administering MSC. Taken together, the present study suggeststhat MSC prevents the increase in SBP in rats with L-NAME-induced hypertension, which may result from the up-regulation of the vascular and renal ecNOS/No system.

• Journal of Korean Neurosurgical Society
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• 제39권3호
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• pp.210-214
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• 2006

Objective : We investigate risk factors of cerebral microbleeds[MBs] and their relation to concomitant magnetic resonance[MR] findings in intracerebral hemorrhages[ICHs] patients. Methods : We studied 100 consecutive patients with primary ICH over a 1-year period. These patients underwent brain MR images using 3.0-T scanners within the first week of the hemorrhage. MBs and old hematomas were located and counted by using $T2^*-weighted$ gradient-echo MR imaging. We also counted lacunes and graded white matter and periventricular hyperintensity on T1- and T2-weighted spin-echo sequences. The association between MBs and vascular risk factors and MR abnormalities were analyzed. Results : MBs were seen in 77 of ICH patients, and their number ranged from 1 to 65 lesions [mean 11, median 6]. The locations of MBs were subcortex-cortex [40.6%], basal ganglia [26.7%], thalamus [14.1 %], brain stem [12.5%], and cerebellum [9.1 %]. Analysis of clinical data revealed that age, hypertension, history of stroke, and duration of hypertension were frequently associated with MBs. The incidence of lacunes, old hematomas, and advanced leukoaraiosis was significantly higher in the MBs group, compared with the patients without MBs. Conclusion : MBs are frequently observed in ICH patients with advancing age, chronic hypertension, and previous hemorrhagic stroke, and are also closely related with morphological signs of occlusive type microangiopathy, such as lacunar infarct and severe leukoaraiosis.

• 농촌의학ㆍ지역보건
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• 제38권2호
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• pp.108-115
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• 2013

본 연구는 인천시 만성질환관리사업을 통해 고혈압, 당뇨병 환자의 혈압 및 혈당이 조절되었는지를 평가하고자 수행하였다. 2010년 1년 간 참여의원에 등록한 11,501명을 대상으로 인천시 사업의 일환으로 진행된 교육과 필수검사에 따라 혈압과 혈당이 조절되었는지를 1년간의 추적관찰을 통해 분석하였다. 연구 결과 고혈압의 경우 등록 시점에서 혈압 조절이 안 된 군은 1년 후 교육이 혈압조절에 효과가 있는 반면, 등록 시점에서 혈압조절이 잘 된 군은 1년 후 필수검사가 혈압 조절에 효과가 있는 것으로 나타났다. 반면, 당뇨병 환자의 혈당 조절과 교육 및 필수검사와의 관련성은 확인하지 못하였다. 본 연구결과를 통해 향후 고혈압 환자의 효과적인 만성질환 관리를 위해서는 교육과 필수검사의 활성화가 중요하며 이를 위한 적극적인 노력이 필요할 것으로 생각된다.

• 한국지능정보시스템학회:학술대회논문집
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• 한국지능정보시스템학회 2001년도 The Pacific Aisan Confrence On Intelligent Systems 2001
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• pp.496-507
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• 2001

An expert system for the diagnosis and indication of hypertension is implemented through HTML-based backward inference. HTML-based backward inference is performed using the hypertext function of HTML, and many HTML files, which are hyperlinked to each other based on the backward rules, should be prepared beforehand. The development and maintenance of the HTML files are conducted automatically using the decision graph. Still, the drawing and input of the decision graph is a time consuming and tedious job if it is done manually. So, automatic generator of the decision graph for the diagnosis and indication of hypertension was implemented. The HTML-based backward inference ensures accessibility, multimedia facilities, fast response, stability, easiness, and platform independency of the expert system. So, this research reveals that HTML-based inference approach can be used for many Web-based intelligent site with fast and stable performance.

• The Korean Journal of Physiology and Pharmacology
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• 제17권1호
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• pp.1-8
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• 2013

Understanding the cellular and molecular mechanisms involved in the development and progression of pulmonary hypertension (PH) remains imperative if we are to successfully improve the quality of life and life span of patients with the disease. A whole plethora of mechanisms are associated with the development and progression of PH. Such complexity makes it difficult to isolate one particular pathway to target clinically. Changes in intracellular free calcium concentration, the most common intracellular second messenger, can have significant impact in defining the pathogenic mechanisms leading to its development and persistence. Signaling pathways leading to the elevation of $[Ca^{2+}]_{cyt}$ contribute to pulmonary vasoconstriction, excessive proliferation of smooth muscle cells and ultimately pulmonary vascular remodeling. This current review serves to summarize the some of the most recent advances in the regulation of calcium during pulmonary hypertension.

• 한국정보시스템학회:학술대회논문집
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• 한국정보시스템학회 2003년도 춘계학술대회
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• pp.271-285
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• 2003

In the conduct of this study, a web-enabled healthcare system for the management of hypertension was implemented through a hyperlink-based inference approach. The hyperlink-based inference platform implemented using the hypertext capacity of HTML which ensured accessibility, multimedia facilities, fast response, stability, ease of use and upgrade, and platform independency of expert systems. Many HTML documents, which are hyperlinked to each other based on expert rules, were uploaded beforehand to perform the hyperlink-based inference. The HTML documents were uploaded and maintained automatically by our proprietary tool called the Web-Based inference System (WeBIS) that supports a graphical user interface (GUI) for the input and edit of decision graphs. Nevertheless, the editing task of the decision graph using the GUI tool is a time consuming and tedious chore when the knowledge engineer must perform it manually. Accordingly, this research implemented an automatic generator of the decision graph for the management of hypertension. As a result, this research suggests a methodology for the development of Web-enabled healthcare systems using the hyperlink-based inference approach and, as an example, implements a Web-enabled healthcare system for hypertension, a platform which peformed especially well in the areas of speed and stability.