• 한국의류산업학회지
• /
• 제8권3호
• /
• pp.331-335
• /
• 2006

주방세제로 유도한 건성피부에 대한 Palmarosa, Neroli essential oil의 유효성 연구결과는 다음과 같다. 단백질 분석결과 Neroli essential oil 처리 군이 대조군과 가장 유사하게 나타났고 그 다음으로 Palmarosa + Neroli essential oil 처리 군이 대조군과 유사하게 복구되어 가고 있는 것으로 나타났고 그 다음으로 Palmarosa의 순이다. 표피층의 형태적 관찰결과로는 Palmarosa essential oil에 의한 각질층의 이탈과 Neroli essential oil에 의한 각질층의 복구에 의한 표피층의 비후 현상을 볼 수 있었으나 각각의 오일 처리군에서 계면활성제 처리 후 피부 염증에 대한 재생효과가 있음을 알 수 있었다. 염증 반응을 알아보기 위한 Mast Cell 실험에서 보면 대조군에 비해 계면활성제 연속처리군에서는 mast cell의 크기와 수가 증가되었음을 확인 할 수 있다. Neroli essential oil이 처리된 각각의 군에서는 mast cell의 수가 확연히 감소된 것을 볼 수 있다.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제35권6호
• /
• pp.390-395
• /
• 2013

Locoregional recurrence of tongue cancer is higher than that of other sites of the oral cavity. Locoregional control has shown improvement over the past 20 years, however, a high rate of recurrence and second primary tumor occurrence is still frequently reported. Leukoplakia is a clinical term, which describes a whitish lesion of the oral cavity. Clinicopathologic features may range from hyperkeratosis to malignancy. Because of its diverse pathologic characteristics, management of this lesion for diagnosis, treatment planning, establishment of a clear surgical margin, and periodic follow-up is difficult. We report on a case of successfully treated tongue cancer which developed from leukoplakia over 10 years. Periodic follow-up strategy and surgical planning are most important to management of locoregional recurrence.

• 생약학회지
• /
• 제44권4호
• /
• pp.391-396
• /
• 2013

In this study, we investigated the effects of onion(Allium cepa L.) peel extraction aplication on UVB-induced damage of mouse skin. The male C57BL/6 weeks mice were divided into three groups; the control group(Con), the UVB irradiated group(UVB) and the group treated with onion peel extract after UVB irradiation(UVB+Onion peel). Onion peel extraction were topically treated after UVB irradiation(800 $mJ/cm^2$) to dorsal skin. We were measured TEWL, melanin value, erythema index and histological of mouse skin. In the TEWL, melanin value and erythema index observation, UVB+onion peel group were decreased then in the UVB group and 120 and 168 hr groups were similar to the control group. In the histological observation, UVB+onion peel group were indicated hyperkeratosis then in the UVB. These results showed that onion peel extract as a topical application may have preventive effect against UVB-induced skin damage. Therefore onion peel extract might be good material for UVB-damage skin care.

• 대한두경부종양학회지
• /
• 제33권2호
• /
• pp.29-33
• /
• 2017

Verrucous carcinoma was first described by Ackerman who reported a case of verrucous carcinoma of the oral cavity. While it is primarily occurred in oral cavity, larynx is the second most affected site, accounting for nearly 35% of cases. It is a rare variant of well-differentiated squamous cell carcinoma and comprises 1% to 4% of all laryngeal carcinomas. It is characterized by locally invasive, slow growth and the surface shows papillary fronds with prominent hyperkeratosis. Because of the benign appearance and difficulty of the tissue diagnosis, it is often undiagnosed or misdiagnosed. The primary treatment modality is surgery and the extent of surgical resection may be guided by T stage. We experienced a case of verrucous carcinoma of larynx in a patient with hoarseness lasted for about 2 years and had difficult to diagnosis and treatment. Therefore we report this case with a brief review of literature.

• 한국동물번식학회:학술대회논문집
• /
• 한국동물번식학회 2004년도 춘계학술발표대회
• /
• pp.215-215
• /
• 2004

Human papillomavirus type 16 (HPV16) has been known as a major causative factor for the development of uterine cervical carcinomas. To investigate the in vivo activity of HPV16 expressed in squamous epithelia, transgenic mice harboring HPV16 E6/E7 with human keratin 14 (hK14) promoter were generated. Grossly, hK14 driven HPV16 E6/E7 transgenic mice exhibited multiple phenotypes, including wrinkled skin that was apparent prior to the appearance of hair in neonates, thickened ears, and loss of hair in adults. (omitted)

• Journal of Oral Medicine and Pain
• /
• 제35권4호
• /
• pp.237-243
• /
• 2010

흑색극세포증은 대개 피부가 접히는 부위에서 짙은 색의 반점과 함께 벨벳양상을 가진 두꺼워진 피부 그리고 혀, 치은, 점막, 구개를 포함하는 구강내 및 입술부위의 유두종증의 특징을 가진다. 그중에서도 악성 흑색극세포증은 기저 암종과 연관되어 발생되며 특징적으로 입술과 눈꺼풀의 개화성 유두종증, 손바닥 및 발바닥의 저명한 과각화증, 레제르-트렐라 증후와 같은 세가지 특징이 나타난다. 본 증례의 환자에서 악성 흑색극세포증의 전형적인 임상적 그리고 조직학적 특징과 함께 악성 위장 선암종의 병력을 가지고 있었다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제42권5호
• /
• pp.284-287
• /
• 2016

Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is characterized by various embryological deformities and carcinoma formation. It is caused by PTCHI gene mutations and is autosomal dominantly inherited. Some of the main symptoms of NBCCS are multiple basal cell carcinomas, multiple keratocystic odontogenic tumors (KCOTs) of the mandible, hyperkeratosis of the palmar and plantar, skeletal deformity, calcification of the falx cerebri, and facial defomity. Recurrent KCOT is the main symptom of NBCCS and is present in approximately 90% of patients. In NBCCS, KCOTs typically occur in multiples. KCOTs can be detected in patients under the age of 10, and new and recurring cysts develop until approximately the age of 30. The postoperation recurrence rate is approximately 60%. This case report presents a 14-year-old female patient with a chief complaint of a cyst found in the maxilla and mandible. The patient was diagnosed with NBCCS, and following treatment of marsupialization and enucleation, the clinical results were satisfactory.

• Clinical and Experimental Pediatrics
• /
• 제46권11호
• /
• pp.1135-1138
• /
• 2003

저자들은 어린선과 과각화증의 특징적인 피부 소견과 결막염, 청력 소실로 KID 증후군이 진단된 환자에서 심한 성장 장애와 담즙 정체, 단백뇨가 동반된 1례를 경험하였기에 이를 보고하는 바이다.

• 한국의류산업학회지
• /
• 제9권5호
• /
• pp.569-572
• /
• 2007

The effectiveness of Palmarosa, Neroli and Jasmin blending oil on dry skin of rat induced by kitchen detergent are investigated. The experimental groups were divided the control group, group treated with surfactant, group treated with Palmarosa and Neroli, and group with Palmarosa, Neroli and Jasmin. Observation of epidermis and the alteration of mast cell were performed with photomicroscope. According to the epidermis morphological changes analysis, the A3 group treated with Palmarosa, Neroli and Jasmin blending oil was appeared the most similar with the control group, and the A2 group applied with Palmarosa and Neroli blending oil was sequently displayed similar characteristics. The collagen layer's breakaway resulting from Palmarosa essential oil, the collagen layer's restoration resulting from Neroli essential oil, the collagen layer's retention hyperkeratosis resulting from Jasmin essential oil were observed in the structure of the epidermal layer. In photomicrosope observation of mast cell to examine the inflammatory reactions, the increase in size and number of mast cell were showed in A1 group treated with surfactant compared to the control group. The number of mast cells definitely decreased in groups which were treated with Palmarosa, Neroli and Jasmin blending oil.

• 대한한방소아과학회지
• /
• 제29권2호
• /
• pp.1-15
• /
• 2015

Objectives In the theory of Korean Medicine, Cicadae Periostracum (CP) has been used to treat skin diseases such as inflammatory dermatitis, tetanus and pruritus. CP can reduce heat and disperse wind. In prior studies, anti-allergic effect and anti-inflammatory effect of CP were reported. However, there has been no report regarding the correlation of CP and allergic contact dermatitis (ACD). This study was performed to show the effects of CP in ACD induced by 2,4-dinitrochlorobenzene (DNCB) in mice. Methods In this experiment, the effects of CP on biological changes were measured, such as changes in ear and spleen weight, ear and dorsum skin thickness, clinical aspect on the dorsum skin and histological changes. The effect of proliferation rate of splenocytes was also investigated in vitro and vivo study. Results In results, CP application (CPA) group and CP application and administration (CPAA) group were significantly restrained in ear weight gain and increase in ear and dorsum skin thickness compared to the control group. In addition, CPA and CPAA group showed diminished erythema, desquamation, bloodstain, and marks. Also, the histological assessment showed that CP treatement diminished thickness of epidermis, hyperkeratosis, pigmentation and parakeratosis. Conclusions In conclusion, these data suggest that CP can decrease symptoms of ACD.