• 대한한방내과학회지
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• 제20권1호
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• pp.83-98
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• 1999

This study is designed to investigate the effects of Samul-Tang extract on the response of lactic dehydrogenase(LDH) release, cellular activity, lipid peroxidation, DNA synthesis and the changes of total protein of bovine pulmonary artery endothelial cells(PAEC) from hydrogen peroxide$(H_2O_2)$-induced injury. The results are as follows : 1. Samul-Tang significantly decreased $H_2O_2$-induced release of LDH from injured bovine PAEC. 2. Samul-Tang significantly repressed $H_2O_2$-induced cellular activity from injured bovine PAEC. 3. Samul-Tang significantly repressed $H_2O_2$-induced lipid peroxidation from injured bovine PAEC. 4. Samul-Tang significantly stimulated DNA synthesis in bovine PAEC. 5. Samul-Tang significantly repressed $H_2O_2$-induced changes of total protein volume from injured bovine PAEC. Above results suggest that Samul-Tang can protect bovine PAEC from $H_2O_2$-induced injury. These results can be effectively applied to the prevention and cure of cardiovascular and cerebrovascular diseases.

• 한국자동차공학회논문집
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• 제17권3호
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• pp.142-148
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• 2009

The direct injection(DI) diesel engine has become a prime candidate for future transportation needs because of its high thermal efficiency. However, nitrogen oxides(NOx) increase in the local high temperature regions and particulate matter (PM) increases in the diffusion flame region within diesel combustion. Therefore, the demand for developing a suitable after treatment device has been increased. NOx absorbing catalysts are based on the concept of NOx storage and release making it possible to reduce NOx emission in net oxidizing gas conditions. This De-NOx system, called the LNT(Lean NOx Trap) catalyst, absorbs NOx in lean exhaust gas conditions and release it in rich conditions. This technology can give high NOx conversion efficiency, but the right amount of reducing agent should be supplied into the catalytic converter at the right time. In this research, a performance characteristics of LNT with a hydrogen enriched gas as a reductant was examined and strategies of controlling the injection and rich exhaust gas condition were studied. The NOx reduction efficiency is closely connected to the injection timing and duration of reductant. LNT can reduce NOx efficiently with only 1 % fuel penalty.

• 한국전산유체공학회지
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• 제15권4호
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• pp.67-75
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• 2010

Hydrogen safety is one of important issues for future public usage of hydrogen. When hydrogen is released in a compartment, the occurrence of detonation must be prohibited. In order to evaluate the possibility of DDT (Deflagration to Detonation Transition) in the compartment with the hydrogen release, sigma-lambda criteria which were developed from experimental data are commonly used. But they give a little conservative results because they do not consider the detailed geometrical effect of the compartment. This is the main reason of the need to mechanistic combustion model for evaluation of hydrogen flame propagation and acceleration. In this study, sigma-lambda criteria and combustion model were systematically applied to evaluate a possibility of DDT in a IRWST compartment of APR1400 nuclear power plant during a hypothetical accident. A combustion model in an open source CFD code OpenFOAM has been applied for analyses of hydrogen flame propagation. The model was validated by evaluating the flame acceleration tests conducted in FLAME facility. And it was applied to evaluate the characteristics of a hydrogen flame propagation in the IRWST compartment of APR1400.

• 한국수소및신에너지학회논문집
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• 제34권3호
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• pp.307-315
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• 2023

The physical and chemical changes exhibited by high density polyethylene (HDPE) after treatment with hydrogen at a pressure of 90 MPa followed by rapid release of the hydrogen were studied. X-ray diffraction, differential scanning calorimetry, thermo gravimetric analysis, and attenuated total reflectance (ATR)-fourier transform infrared (FTIR) were used for this purpose. As a result, it was found that the degree of crystallinity of HDPE decreased after hydrogen pressure treatment, while the average thickness of lamellae that constitute the crystals and the melting temperature of the crystalline region actually increased. The decomposition temperature also increased by about 3℃. In addition, it was found that the hydrogen bonding network between -OH groups in the HDPE sample was strengthened and partial chain scission occurred. These cut chains were found to be terminated by oxidative degradation such as cross-linking between chains, -C=O, -C-O, and -CHO, or by the formation of -CH₃ at the chain ends, as confirmed by ATR-FTIR.

• 한국수소및신에너지학회논문집
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• 제26권6호
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• pp.659-665
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• 2015

In this study, an experimental investigation is performed for evaluation of a liquid pool spreading model with continuous release. The model considered in this study was developed based on a concept which means that the liquid pool spreading is governed by a balance between an inertia force from gravity and a frictional force from friction with the ground under the whole base of the liquid pool. For evaluation of the model, experimental study is performed. Experimental apparatus is setup for measuring release rate, spreading velocity, and evaporation rate from a liquid pool. The experimental results are compared with results from the model. By applying release and evaporation rates obtained from experiments to solving the model, liquid pool radius variation according to time can be obtained. For evaluation of an effect of friction force in the spreading model, results obtained from the models with and without the friction force are compared with those obtained from the experiments. As a result, it is shown that there exists a large deviation between the results obtained from the model without the friction force and the experimental results. On the other hand, the tendency of liquid pool radius variation according to time is similar between the results obtained from the model without the friction force and the experimental results.

• 한국산업보건학회지
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• 제25권4호
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• pp.534-541
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• 2015

Objectives: This study was conducted to evaluate the prevalence rate of multiple chemical sensitivity/idiopathic environmental intolerance(MCS/IEI) among workers in the Gumi industrial complex around the region of accidental release of hydrogen fluoride in 2012. Materials: We evaluated MCS/IEI using the Korean version of the Quick Environmental Exposure and Sensitivity Inventory(QEESI). A total of 535 workers at six manufacturing companies in the Gumi industrial complex were investigated using self-administered questionnaires from February to March 2015. After exclusion of incompletely answered questionnaires, 271 were analyzed. Results: The prevalence rate and proved positive rate of MCS/IEI were 5.9%(16 out of 271) and 3.7%(10 out of 271), respectively. The scores of chemical intolerance, other intolerance, symptom severity and life impact were significantly higher(p<0.05) in females than those of males. In terms of masking index scores, males showed significantly higher(p=0.003) than female. The self-reported MCS/IEI prevalence rate, 7.7%, of workers exposed to hydrogen fluoride in 2012 was higher than no-exposure group(5.6%), but not statistically significant(p=0.815). Conclusions: Although the prevalence rate of MCS/IEI symptoms of workers exposed to hydrogen fluoride gas in 2012 was not significantly higher than no-exposure group, it is necessary to conduct follow-up study on the exposure group of hydrogen fluoride.

• 한국수소및신에너지학회논문집
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• 제23권4호
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• pp.316-322
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• 2012

A fuel cell vehicle has the hydrogen detection sensors for checking the hydrogen leakage because it use hydrogen for its fuel and can't use a odorant to protect the fuel cell stack. To verify the hydrogen safety of leakage we select the high possible leak points of fittings in hydrogen storage system and test the leaking behavior at them. The hydrogen leakage flow rate is 10, 40, 118 NL/min and the criterion for maximum hydrogen leakage is based on allowing an equivalent release of combustion energy as permitted by gasoline vehicles in FMVSS301. There are total 18EA hydrogen leakage detection sensors installed in test system. we acquire the hydrogen leakage detection time and determine the ranking. Hydrogen leakage detection time decrease when hydrogen leakage flow rate increase. The minimum hydrogen leakage detection time is about 3 seconds when the flow rate is 118NL/min. In this study, we optimize hydrogen sensor position in fuel cell vehicle and verify the hydrogen leakage safety because there is no inflow inside the vehicle.

• Archives of Pharmacal Research
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• 제26권11호
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• pp.973-978
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• 2003

A polymeric film composed of Carbopol, Poloxamer and hydroxypropyl methylcellulose was prepared to develop a buccal patch and the effects of composition of the film on adhesion time, swelling ratio, and dissolution of the film were studied. The effects of plasticizers or penetration enhancers on the release of triamcinolone acetonide (TAA) were also studied. The hydrogen bonding between Carbopol and Poloxamer played important role in reducing swelling ratio and dissolution rate of polymer film and increasing adhesion time. The swelling ratio of the composite film was significantly reduced and the adhesion time was increased when compared with Carbopol film. As the ratio of Poloxamer to hydroxypropyl methylcellulose increased from 0/66 to 33/33, the release rate of TAA decreased. However, no further significant decrease of release rate was observed beyond the ratio of 33/33. The release rate of TAA in the polymeric film containing polyethylene glycol 400, a plasticizer, showed the highest release rate followed by triethyl citrate, and castor oil. The release rate of TAA from the polymeric film containing permeation enhancers was slower than that from the control without enhancers. Therefore, these observations indicated that a preparation of a buccal patch is feasible with the polymeric film composed of Cabopol, Poloxamer and hydropropyl methylcellulose.

• 대한기계학회논문집B
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• 제29권9호
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• pp.979-987
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• 2005

Numerical simulations were performed at atmospheric pressure in order to understand the effect of additives on flame speed, flame temperature, radical concentrations, $NO_x$ formation, and heat flux in freely propagating $CH_4-Air$ flames. The additives were both carbon dioxide and hydrogen chloride which had a combination of physical and chemical behavior on hydrocarbon flame. In the flame established with the same mole of methane and additive, hydrogen chloride significantly contributed toward the reduction of flame speed, flame temperature, $NO_x$ formation and heat flux by the chemical effect, whereas carbon dioxide mainly did so by the physical effect. The impact of hydrogen chloride on the decrease of the radical concentration was about $1.4\~3.0$ times as large as that of carbon dioxide. Hydrogen chloride had higher effect on the reduction of $EI_{NO}$ than carbon dioxide because of the chemical effect of hydrogen chloride. The reaction, $OH+HCl{\rightarrow}Cl+H_2O$, played an important role in the heat flux from flames added by hydrogen chloride instead of the reaction, $OH+H_2{\rightarrow}H+H_2O$ which was an important reaction in hydrocarbon flames.

• Korean Chemical Engineering Research
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• 제54권4호
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• pp.582-585
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• 2016

ALOHA, PHAST 등의 사고영향평가 프로그램들을 활용하여 전기 전자 등의 산업 분야에서 많이 쓰이며 인체에 유독한 HF 가 누출되는 사고의 발생 시 대피해야 하는 초기 이격거리에 대한 연구를 수행하였다. 다양한 공정조건과 상태로 저장되어 있는 HF의 사고시나리오를 간단하게 정의하기는 어렵지만 화학물질안전원의 지침대로 10분 내 총 저장량 누출을 최악의 시나리오, 결속된 배관의 일부 파열을 대안의 시나리오로 하여 비상상황을 가정하였다. 그로부터 사고모델링의 시작인 누출속도 산정을 한 후 보수적으로 확산모델링을 적용하여 밤과 낮의 대표적인 기상상태에 따라 일반적인 대피거리로 권고되는 ERPG-2 농도가 도달하는 끝점거리를 구하여 현장에서 신속하게 쓸 수 있는 간단한 그래프와 같은 형태로 제시하였다. 이는 유사시를 대비한 사전적인 성격의 그래프로 화학물질 누출사고 시 신속한 비상대응계획을 수립하는 데 도움이 될 것이다.