• Vascular Specialist International
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• 제34권4호
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• pp.88-93
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• 2018

Purpose: This study aimed to compare surgical revisions and balloon angioplasty after surgical thrombectomy on thrombosed dialysis access as a first event. Materials and Methods: Records of patients undergoing creation of arteriovenous grafts (AVGs) at the Gachon University Gil Medical Center between March 2008 and February 2016 were reviewed. Among them, patients who underwent treatment on first-time thrombotic occlusion after AVG creation were identified. Outcomes were primary, primary-assisted, and secondary patency. The patency was generated using the Kaplan-Meier method, and patency rates were compared by log-rank test. Results: A total of 59 de novo interventions (n=26, hybrid interventions; n=33, surgical revisions) for occlusive AVGs were identified. The estimated 1-year primary patency rates were 47% and 30% in the surgery and hybrid groups, respectively. The estimated primary patency rates were not different between the two groups (log-rank test, P=0.73). The Kaplan-Meier estimates of 6 and 12 months for primary-assisted patency rates were 68% and 57% in the surgery group and 56% and 56% in the hybrid group. The Kaplan-Meier estimates of 12 and 24 months secondary patency rates were 90% and 71% in the surgery group and 79% and 62% in the hybrid group. There were no differences in the estimated primary-assisted and secondary patency rates between the two groups. Conclusion: Our results showed no significant difference between the two groups in terms of primary patency (P=0.73), primary-assisted patency (P=0.85), and secondary patency (P=0.78). However, percutaneous transluminal angioplasty can give more therapeutic options for both surgeons and patients.

• Restorative Dentistry and Endodontics
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• 제45권3호
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• pp.31.1-31.20
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• 2020

Matrix metalloproteinases (MMPs) are enzymes that can degrade collagen in hybrid layer and reduce the longevity of adhesive restorations. As scientific understanding of the MMPs has advanced, useful strategies focusing on preventing these enzymes' actions by MMP inhibitors have quickly developed in many medical fields. However, in restorative dentistry, it is still not well established. This paper is an overview of the strategies to inhibit MMPs that can achieve a long-lasting material-tooth adhesion. Literature search was performed comprehensively using the electronic databases: PubMed, ScienceDirect and Scopus including articles from May 2007 to December 2019 and the main search terms were "matrix metalloproteinases", "collagen", and "dentin" and "hybrid layer". MMPs typical structure consists of several distinct domains. MMP inhibitors can be divided into 2 main groups: synthetic (synthetic-peptides, non-peptide molecules and compounds, tetracyclines, metallic ions, and others) and natural bioactive inhibitors mainly flavonoids. Selective inhibitors of MMPs promise to be the future for specific targeting of preventing dentin proteolysis. The knowledge about MMPs functionality should be considered to synthesize drugs capable to efficiently and selectively block MMPs chemical routes targeting their inactivation in order to overcome the current limitations of the therapeutic use of MMPs inhibitors, i.e., easy clinical application and long-lasting effect.

• The Journal of Advanced Prosthodontics
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• 제9권6호
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• pp.447-452
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• 2017

PURPOSE. To evaluate the sealing performance of Hybrid Coat and its influence on the shear bond strength of five dentin surface cements. MATERIALS AND METHODS. Six premolars were pretreated to expose the dentin surface prior to the application of Hybrid Coat. The microscopic characteristics of the dentinal surfaces were examined with scanning electron microscopy (SEM). Then, 40 premolars were sectioned longitudinally, and 80 semi-sections were divided into a control group (untreated) and a study group (treated by Hybrid Coat). Alloy restoration was bonded to the teeth specimen using five different cements. Shear bond strength was measured by the universal testing machine. The fracture patterns and the adhesive interface were observed using a stereomicroscope. RESULTS. SEM revealed that the lumens of dentinal tubules were completely occluded by Hybrid Coat. The Hybrid Coat significantly improved the shear bond strength of resin-modified glass ionomer cement (RMGIC) and resin cement (RC) but weakened the performance of zinc phosphate cement (ZPC), zinc polycarboxylate cement (ZPCC) and glass ionomer cement (GIC). CONCLUSION. Hybrid Coat is an effective dentinal tubule sealant, and therefore its combined use with resin or resin-modified glass ionomer cements can be applied for the prostheses attachment purpose.

• Journal of the Korean Wood Science and Technology
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• 제47권2호
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• pp.200-209
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• 2019

To improve the water resistance of melamine-urea-formaldehyde (MUF) resins, different levels of blocked polymeric 4,4 diphenyl methane diisocyanate (B-pMDI) were blended with MUF resins to prepare B-pMDI/MUF hybrid adhesives, and their adhesion performances were evaluated for the surface lamination of fancy veneer on plywood. FT-IR spectra showed that the de-blocked -NCO groups reacted with the -OH of hydroxymethyl groups of the MUF resins to form urethane bonds at 2% B-pMDI/MUF, which was detected before and after their hydrolysis. The mass loss after the hydrolysis consistently decreased as the B-pMDI level increased, indicating an improvement in the water resistance. As the B-pMDI level increased, the activation energy of hybrid adhesives decreased, which improved the reactivity of the hybrid adhesives. Additionally, the water resistance improvement of the hybrid adhesives increased the tensile shear strength of the surface laminated plywood in semi-water proof and water-proof by 23 % and 8 %, respectively, at 2% B-pMDI level. This was likely due to the urethane linkages in the hybrid adhesives. However, the formaldehyde emission from plywood panels bonded with the hybrid adhesives increased in the dry state, indicating incomplete curing of the hybrid adhesives.

• Composites Research
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• 제28권1호
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• pp.1-5
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• 2015

In this paper the influence of fiber orientation of basalt and carbon inter-ply fabrics on the flexural properties of hybrid composite laminates was experimentally investigated. Four types of basalt/carbon/epoxy inter-ply hybrid composite laminates with varying angle ply orientation of reinforced basalt fiber and fixed orientation of carbon fiber were fabricated using hand lay-up technique. Three point bending test was performed according to ASTM 7264. The fracture surface analysis was carried out by scanning electron microscope (SEM). The results obtained from the four laminates were compared. Lay-up pattern of $[0B/+30B/-30B/0C]_S$ exhibits the best properties in terms of flexural strength and flexural modulus. Scanning electron microscopy results on the fracture surface showed that the interfacial de-bonding between the fibers and epoxy resin is a dominant fracture mode for all fiber lay-up schemes.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2010년도 추계학술대회 초록집
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• pp.95-95
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• 2010

In recent, there are tremendous requirements to improve the fuel economy of vehicle. For satisfaction of requirements, Hybrid Electric Vehicle or other technologies are suggested and implemented. However, it should be noted that almost 35% energy loss is occurred in the shape of exhaust gas as ever. For increase the efficiency of vehicle, it is certain that the exhaust gas energy should be recover, and generate energy. In previous studies, the technologies such as turbo-compound, thermoelectric and rankine cycle are suggested to recover the exhaust heat energy in vehicle. But, they focus on the conventional vehicle or parallel Hybrid Electric Vehicle. Series Hybrid Electric Vehicle has advantage that the engine and drive shaft are de-coupled. It means that the engine can be operated in high efficiency area regardless with vehicle states. Therefore, if rankine cycle is applied to series hybrid electric vehicle, operating condition of that becomes almost steady. So, in this study, theoretical analysis on the efficiency of rankine cycle applied to series hybrid electric city bus is carried and the energy recovered from exhaust gas during vehicle drive cycle is calculated.

• Journal of Power Electronics
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• 제3권3호
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• pp.145-150
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• 2003

Reliability, availability, and cost have been the major concerns for photovoltaic hybrid systems since their beginning as primary sources for much critical applications like communication units and repeaters. This paper descnbes the performance of two hybrid systems, photovoltaic-battery, wind-turbine coupled with the public-grid (PVBWG) hybrid system and photovoltaic-battery, wind-turbine coupled With the diesel generator (PVBWD) hybrid system The systems are sized to power a typical 300W/48V de telecommunication load continuously throughout the year Such hybrid systems consist of subsystems, which in turn consist of components Failure of anyone of these components may cause failure of the entire system. The reliability and availability basics, and estimation procedure for the two proposals are introduced also in this paper. The PVBWG and PVBWD system configurations are shown with the relevant mean-time-between-faIlure (MTBF) and failure rate (${\lambda}$) of each component. The characteristics equations of the two systems are deduced as a function of operating hours and the percentage of sun and wind availabilities per day. The system probability failure as well as the reliability is estimated based on the fault tree analysis technique. The results show that, by using standard or normal components MTBF, the PVBWG is more reliable and the time of periodic maintenance period is more than one year especially in the rich sites of both sun and wind, but PVBWD competes else Also, in the first five years from the system installation, the system is quit reliable and may not require any maintenance. The results show also, as the sun and wind are available, as the system reliable and available.

• Steel and Composite Structures
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• 제22권1호
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• pp.113-139
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• 2016

The nonlinear seismic responses of steel buildings with perimeter moment resisting frames (PMRF) and interior gravity frames (IGF) are estimated, modeling the interior connections first as perfectly pinned (PPC), and then as partially restrained (PRC). Two 3D steel building models, twenty strong motions and three levels of the PRC rigidity, which are represented by the Richard Model and the Beam Line Theory, are considered. The RUAUMOKO Computer Program is used for the required time history nonlinear dynamic analysis. The responses can be significantly reduced when interior connections are considered as PRC, confirming what observed in experimental investigations. The reduction significantly varies with the strong motion, story, model, structural deformation, response parameter, and location of the structural element. The reduction is larger for global than for local response parameters; average reductions larger than 30% are observed for shears and displacements while they are about 20% for bending moments. The reduction is much larger for medium- than for low-rise buildings indicating a considerable influence of the structural complexity. It can be concluded that, the effect of the dissipated energy at PRC should not be neglected. Even for connections with relative small stiffness, which are usually idealized as PPC, the reduction can be significant. Thus, PRC can be used at IGF of steel buildings with PMRF to get more economical construction, to reduce the seismic response and to make steel building more seismic load tolerant. Much more research is needed to consider other aspects of the problem to reach more general conclusions.

• 대한화학회지
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• 제54권4호
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• pp.363-373
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• 2010

마약인 모르핀, 헤로인, 코데인, 펜타조신 그리고, 버프레노파인에 대하여 범밀도함수이론에 근거하여 계산 연구를 수행하였다. 약물특이 분자단과 치환기의 기하학적 파라미터는 B3LYP/6-31+G(d) 레벨로 계산하였고, 전자의 구조는B3LYP/6-311++G(d,p) 레벨로 같은 혼성 범함수를 사용하여 계산하였다. 원자의 전하분포는 Mulliken 개체 수 분석에 의하여 구하였다. 보고된 생물학적 활성, 계산된 분배 계수, 전자 및 기하학적 분석을 토대로 펜타조신과 버프레노파인을 새로 제시된 유사화합물에 대한 모델화합물로 선택하였으며, 이들 유사화합물에 대하여 연구한 뒤, 모델화합물과 비교하였다. 본 연구 결과는 약물특이 분자단의 기하학적 구조와 전자 구조가 다른 치환기의 존재 하에서도 변함없이 유지된다는 것을 보여주었다. 제시된 유사화합물들도 모델 분자의 특성을 갖고 있기 때문에, 이들 유사화합물들도 생물학적 활성을 나타낼 것 같다.

• Journal of Chest Surgery
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• 제43권6호
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• pp.774-777
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• 2010

확장성 심근증이 있던 70세 남자 환자가 좌측 신장결석으로 입원하여 검사 중 신상부 복부대동맥류가 발견되었다. 환자의 상태가 좋지 않아 혈관 내 스텐트를 이용한 하이브리드 수술을 시행하였다. 수술은 비뇨기과에서 좌측 신장결석을 제거 후에 복부대동맥의 내장동맥과 양측 신동맥등 복부대동맥의 가지혈관의 근위부를 결찰하고 이어 좌측 외장골동맥 근위부로부터 2개의 Y-그라프트를 이용하여 역행성 우회수술로 가지혈관들의 재관류를 하고는 복부대동맥에는 스텐트 그라프트를 설치하였다. 이에 저자들은 신상부 복부대동맥류 환자의 하이브리드 술식을 치험하였기에 보고하는 바이다.