• Journal of Acupuncture Research
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• v.19 no.5
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• pp.149-160
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• 2002

Objetive : To evaluate the effect of treatment for Heel Pain by using Bee-venom Acupuncture that is well known for anti-inflamatory effect and function of activating immunine system. Methods : We investigated 32 cases of patient with Heel Pain. From 1th November 2001 to 30th June 2002, 32 cases of patient with Heel Pain treated at the Department of Acupuncture & Moxibustion of Kyung-won University Oriental Hospital were selected for two group. One group was treated by Bee-venom Acupuncture therapy (Bee-venom Acupuncture Group : BAG), the other group was treated by Common Acupuncture therapy (None Bee-venom Acupuncture Group : NBAG). Both group were composed of 16 patients. After treatment, we evaluated the effects per each group. Results : 1. In the distribution by sex & age : 5 cases were male, 11 cases were female in BAG. 10 cases were male, 6 cases were female in NBGA. Forty aged cases were the most in BAG. Thirty aged cases were the most in NBAG. 2. Assessment of treatment by therapeutic frequency : 14 cases(87.5%) were above "Fair" within 6 times in BAG, 7 cases(43.8%) were above "Fair" beyond 10 times. 3. Assessment of treatment : Excellent were 9 cases, Good 5 cases, Fair 2 cases in BAG, Excellent were 2 cases, Good 7 cases, Fair 2 cases, Poor 5 cases in NBAG. Therapeutic effect above "Fair" were 16 cases(100%) in BAG, 11 cases(68.8%) in NBAG. 4. Comparing BAG with NBAG by therapeutic frequency and assessment in Grade II state : 11 cases(91.7%) were above "Good" within 6 times in BGA, 3 cases (57.1%) above "Fair" beyond 10 times. 5. About average frequency of treatment in the distribution of Grade : Grade III was 5.3 times, Grade II 4.0 times in BGA, whereas Grade III 16.0 times, Grade II 8.4 times in NBGA. Conclusions : In the treatment of Heel Pain, the Bee-venom Acupuncture can be regarded as more useful method in the clinical practice, because it has comparatively shorter duration of treatment and is more effective.

• BMB Reports
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• v.44 no.10
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• pp.647-652
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• 2011

The protein transduction domains have been reported to have potential to deliver the exogenous molecules, including proteins, to living cells. However, poor transduction of proteins limits therapeutic application. In this study, we examined whether imipramine could stimulate the transduction efficiency of PEP-1 fused proteins into astrocytes. PEP-1-catalase (PEP-1-CAT) was transduced into astrocytes in a time- and dose-dependent manner, reducing cellular toxicity induced by $H_2O_2$. Additionally, the group of PEP-1-CAT + imipramine showed enhancement of transduction efficiency and therefore increased cellular viability than that of PEP-1-CAT alone. In the gerbil ischemia models, PEP-1-CAT displayed significant neuroprotection in the CA1 region of the hippocampus. Interestingly, PEP-1-CAT + imipramine prevented neuronal cell death and lipid peroxidation more markedly than PEP-1-CAT alone. Therefore, our results suggest that imipramine can be used as a drug to enhance the transduction of PEP-1 fusion proteins to cells or animals and their efficacies against various disorders.

• Korean Journal of Food Science and Technology
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• v.36 no.1
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• pp.25-31
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• 2004

Characteristics of good-quality red pepper powder produced using $N_{2}$-circulated low-temperature drying method were compared with those made through conventional sun and hot-air drying methods. Kimchi and kochujang were prepared with different types of red pepper powder, and their physicochemical and sensory properties were compared. Results revealed Hunter L (lightness), a (redness), and b (yellowness) values of $N_{2}$-circulated low temperature-dried red pepper were highest. Absorbance of crude capsanthin in hot air-dried red pepper powder ($0.584{\pm}0.001$) was significantly lower than sun-dried ($0.848{\pm}0.001$) and $N_{2}$-circulated low temperature-dried products ($0.832{\pm}0.002$. Use of $N_{2}$-circulated low-temperature drying method resulted in the highest amounts at reducing sugar and total vitamin C. Capsaicin content of $N_{2}$-circulated low temperature-dried products were higher than hot air-dried ones. The aL values of kochujaug made with sun-and low temperature-dried red peppers were higher than that of kochujang made with hot-dried red peppers. Physicochemical and sensory evaluation results showed red pepper powders made using $N_{2}$-circulated low-temperature drying method have the best quality among all samples tested.

• Journal of Korean Society on Water Environment
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• v.29 no.5
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• pp.598-609
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• 2013

Spatial and temporal distribution of environmental factors and epilithic diatom communities in major rivers (30 rivers and 58 sampling points) of the Korean peninsula were surveyed each one time before (May) and after the monsoon (October) 2012. The stream of the east harbor (EAST), the south harbor (SOUTH), and the west harbor (WEST) was sampled in order. Over the survey, a total of 284 taxa were classified, and the number of diatom species in each harbor did not show significant changes after the monsoon, but a biomass significantly decreased. Results also showed that EAST deterioration of water quality and chlorophyll-a after the monsoon, was opposite to SOUTH. Five major dominant species including Nitzschia inconspicua, which contained higher biomass over the survey, were common species which widely distributed in brackish water. Indicator Species Analysis showed that a large number of clean water species in EAST and polluted water species in SOUTH and WEST were emerged respectively. In sum, the Asian monsoon significantly decreased a biomass of epilithic diatoms and water qualities over the harbors (lower stream) in the Korean peninsula, but did not change the major species indicating water quality.

• Journal of Dental Rehabilitation and Applied Science
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• v.37 no.4
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• pp.274-280
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• 2021

Intentional replantation has been used for alternative treatment for conventional root canal therapy. This case report describes that the intentional replantation with application of extrusive orhodontic force for 6 weeks, on which tooth of previous root canal therapy. As preapplicatory orthodontic force, tooth moblity was increased so that extraction of the designated tooth was more easily accomplished and augmented volume of periodontal ligament is expected to acceleated gingival reattachment.

• Restorative Dentistry and Endodontics
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• v.48 no.2
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• pp.18.1-18.10
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• 2023

Objectives: This study aimed to determine whether collagen triple helix repeat containing-1 (CTHRC1), which is involved in vascular remodeling and bone formation, can stimulate odontogenic differentiation and angiogenesis when administered to human dental pulp stem cells (hDPSCs). Materials and Methods: The viability of hDPSCs upon exposure to CTHRC1 was assessed with the WST-1 assay. CTHRC1 doses of 5, 10, and 20 ㎍/mL were administered to hDPSCs. Reverse-transcription polymerase reaction was used to detect dentin sialophosphoprotein, dentin matrix protein 1, vascular endothelial growth factor, and fibroblast growth factor 2. The formation of mineralization nodules was evaluated using Alizarin red. A scratch wound assay was conducted to evaluate the effect of CTHRC1 on cell migration. Data were analyzed using 1-way analysis of variance followed by the Tukey post hoc test. The threshold for statistical significance was set at p < 0.05. Results: CTHRC1 doses of 5, 10, and 20 ㎍/mL had no significant effect on the viability of hDPSCs. Mineralized nodules were formed and odontogenic markers were upregulated, indicating that CTHRC1 promoted odontogenic differentiation. Scratch wound assays demonstrated that CTHRC1 significantly enhanced the migration of hDPSCs. Conclusions: CTHRC1 promoted odontogenic differentiation and mineralization in hDPSCs.

• Proceedings of the KSME Conference
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• 2007.05b
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• pp.3221-3223
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• 2007

Recently, nuclear power plant companies have been extending the turbine valve test interval to reduce the potential of the reactor trip accompanied with a turbine valve test and to improve the NPP's economy through the reduction of unexpected plant trip or decreased operation. In these regards, the extension of the test interval for turbine valves was reviewed in detail. The effect on the destructive overspeed probability due to the test interval change of turbine valves is evaluated by Fault Tree Analysis(FTA) method. Even though the test interval of turbine valves is changed from 1 month to 3 months, the analysis result shows that the reliability of turbine over speed protection system meets acceptance criteria of 1.0E-4/yr. This result will be used as the technical basis on the extension of the test interval for turbine valves. In this paper, the propriety of the turbine valve test interval extension is explained through the review on the turbine valve test interval status of turbine overspeed protection system, the analysis on the annual turbine missile frequency and the probability evaluation of the destructive overspeed due to the test interval extension.

• Korean Journal of Bronchoesophagology
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• v.10 no.2
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• pp.68-71
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• 2004

Thymic cysts are uncommon tumors which usually occur in the neck and mediastinum. It is known to arise from embryonic remnants of the thymopharyngeal duct or from inflammation of thymic tissues. Patients with thymic cyst are often asymptomatic and identified after surgical removal and histologic examination. We experienced a 73 year-old man with recently developed dyspnea. During the examination, chest CT showed a $5\times6cm$ sized cystic mass causing deviation of the trachea. It was located in between the right thyroid gland and anterior mediastinum. It also caused tracheal narrowing noted by bronchoscopy. Right anterior cervical incision and removal of the mass was performed and a histological diagnosis of thymic cyst was confirmed. The patient was discharged without complication.

• Proceedings of the Korean Information Science Society Conference
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• 2005.11a
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• pp.994-996
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• 2005

P2P 그리드 컴퓨팅 환경에서 피어의 자율성으로 인한 자원 제공의 휘발성과 피어의 이질적인 특성은 스케줄링 과정에서 해결해야 할 중요한 문제이다. 이에 본 논문에서는 이동 에이전트 기반 적응적 그룹 스케줄링 기법(Mobile Agent based Adaptive Group Scheduling Mechanism: MAAGSM)을 제안한다. 제안 기법은 피어의 특성 (즉, 자원제공자 자율성 고장, 자원제공자 가음용, 자원 제공 시간)에 따라 피어들을 동질적인 그룹(자원제공자 그룹)으로 구성한 후, 그룹에 적합한 다양한 스케줄링 알고리즘은 이동에이전트 기술을 이용하여 적용한다.

• Proceedings of the Korean Information Science Society Conference
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• 2005.11a
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• pp.991-993
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• 2005

데스크탑 그리드(Desktop Grid) 환경에서는 자원 제공자인 데스크탑의 자율적 연산 참여와 탈퇴를 허용하기 때문에 기존 데스크탑 그리드 시스템들은 연산 도중 잦은 중단으로 인해 연산의 완료 시간이 지연되고, 연산 수행의 신뢰성이 저하되며 연산의 완료를 보장하지 못하고 있다. 기존의 데스크탑 그리드 시스템들은 이러한 데스크탑의 동적 특성을 반영하지 못하고 있을 뿐만 아니라 데스크탑의 연산 수행 양식을 고려하지 않아 시스템의 안정성과 성능이 저하되었다. 신뢰성 높은 연산 수행을 지원하고, 데스크탑의 비예측적 연산 수행 속성을 극복하기 위해서는 데스크탑의 동적인 특성인 휘발성(volatility)을 고려한 스케줄링이 필요하다. 본 논문에서는 휴리스틱 접근을 통해 동적으로 가변하는 데스크탑의 상태를 보다 정확하게 모델링 하는 가용성 기반 마코브 작업 스케줄링 기법을 제안한다. 제안 기법은 데스크탑의 가용성을 기반으로 과거 연산 수행에 대한 패턴을 확률 모델링하여 미래 연산 수행 유형을 예측함으로써 연산 수행 도중의 불안정한 자원 제공 현상을 완화시키며 안정적인 스케줄링을 지원하여 시스템의 신뢰성과 성능을 향상시킨다.