• 한국정밀공학회지
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• 제22권8호
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• pp.57-63
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• 2005

Development of a locomotive mechanism fer the capsule type endoscopes will largely enhance the ability to diagnose disease of digestive organs. In connection with it, most of researches have focused on an installable locomotive mechanism in the capsule. In this paper, it is introduced that the movement of a capsule type endoscope in digestive organ can be manipulated by magnetic force produced outside human body. Since the magnetic force is provided by permanent magnets, no additional power supply to the capsule is required. Using a robotic manipulator for locating the external magnet, the capsule motion control system can cover the whole human digestive organs. This study is particularly concentrated on dither motion effect to improve the mobility of capsule type endoscope. It was experimentally found out that the friction coefficient between the capsule and digestive organ can be remarkably reduced by superposing yawing or rolling dither motion on the translatory motion. In this paper, the experimental results obtained with the direction, amplitude and frequency of sinusoidal dither motion changed is reported.

• 대한한의학원전학회지
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• 제19권1호통권32호
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• pp.128-136
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• 2006

This study is on Yoshimasu Todo's thought of medicines. Conclusions are as below. Medicines are poisons. Therefore, they don't have the ability to restore the vital energy. Medicine-processing(法製) can only be done for doubling the toxicity, since the poison itself is the very effect of a medicine. One poison has an ability to treat only one main symptom. If the poison strikes the main symptom right, it doesn't harm the human body. Since warm-heat-cool-cold(溫熱凉寒) of a medicine can't be known by human ability, it can't be used as the standard of judgment when selecting a medicine.

• Biomolecules & Therapeutics
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• 제6권3호
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• pp.317-327
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• 1998

The subchronic toxicity study of rHuEPO, a newly developed recombinant erythropoietin, was investigated for 13 weeks in Beagle dogs intravenously treated with doses of 100, 500 and 2,500 lU/kg/day. There were no significant changes in body weight, food intake, physical and opthalmic examination, urine analysis, etc. Any toxic response was not observed except for enlarged spleen and extramedullary hematopoiesis. These results indicate that the no-observed adverse effect level (NOAEL) of rHuEPO is 100 lU/kg in Beagle dogs.

• Food Science and Biotechnology
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• 제15권1호
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• pp.158-161
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• 2006

This study was designed to determine possible weight loss effects of Hangbisan, an oriental medicine, on Sprague-Dawley (SD) rats. SD rats that were fed a high-fat diet for 6 weeks to induce obesity and subsequently fed with a basic diet containing 10%(w/w) Hangbisan or 10%(w/w) cellulose for 8 weeks. The Hangbisan fed rats demonstrated a significantly (p<0.05) reduced weight gain compared to the cellulose fed rats as well as a reduced level of plasma cholesterol and triglycerides and an increased level of (HDL)-cholesterol. These results suggest that dietary Hangbisan has an anti-obesity effect in the high-fat diet-induced obesity (DIG) rat and therefore a potential use as an anti-obesity agent in the application of oriental medicine compounds.

• 산업경영시스템학회지
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• 제21권45호
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• pp.333-346
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• 1998

By progress of technology, it became possible for us to do many kinds of operations in virtual environment. However side effect is called simulator sickness may occur to human body when human come in contact with this new environment. It makes symptoms similar to motion sickness. Many studies about that were started in 1950s and have actively been progressing in other countries, but in Korea recognition about that field is insufficient. Main contribution of this paper would be the base study about phenomena of simulator sickness which may be occurs in simulator or virtual reality environment, factors which induce simulator sickness, and quantifying methods of simulator sickness.

• 전기전자학회논문지
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• 제12권4호
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• pp.185-195
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• 2008

본 논문에서는 PCS(Personal Communication System) 대역에서 동작하는 PIFA(Planar Inverted F Antenna)를 설계하여 특성을 살펴보았다. 설계된 PIFA를 폴더와 바, 슬라이드 타입의 단말기에 장착하여 성능을 확인하였다. 실제 사용자가 사용하는 상태와 가장 유사한 환경을 만들기 위해 헤드 팬텀과 핸드 팬텀을 추가하여 단말기 안테나의 성능에 미치는 영향을 분석하였다. 인체의 영향으로 인해 방사패턴이 크게 변형되는 모습을 보였으며, 안테나 효율 또한 현저히 저하되는 것을 전산 모의 실험을 통해 확인할 수 있었다. 단말기와 헤드 팬텀과의 위치 관계에 따른 변화를 확인하기 위해 단말기와 헤드 팬텀의 각도가 $0^{\circ}$일 경우를 기준으로 하여, $2^{\circ},\;4^{\circ}$로 변화시켜가며 단말기 안테나의 성능 변화를 살펴보았다. 그 결과 안테나가 헤드 팬텀에서 멀어질수록 지향성을 갖던 특성이 조금씩 줄어들면서 효율이 좋아지는 경향을 보였다. 다만 안테나의 위치가 상대적으로 헤드 팬텀에 가까운 바 타입의 경우, 이 같은 경향이 나타나지 않았다. 단말기의 형태도 성능에 큰 영향을 주는 것을 확인할 수 있었다.

• 한국산업경영시스템학회:학술대회논문집
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• 한국산업경영시스템학회 2002년도 춘계학술대회
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• pp.243-257
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• 2002

A study on processing for producing cure seat radiated by Original Infrared Rays and Magnatic force. We are well aware that Original Infrared Rays and Magnatic force influence on our human body benificially. In the technical background of this research product, we treated that the product has some operations of ceramic hardwood charcoal, far infrared rays and magnetic, so it can serve large part curative values made of far infrared rays and magnetic force of ceramics. Also, in the special quality of the product deal with ceramic, hard charcoal, ferrite, gelatin what is needed in production. And among them, ferrite, ceramic and hard charcoal are introduced by the manufacturing process of the moleculeization. In concluding, this study described the manufacturing process on the basis of the worksheets and arranged the useful effect which effect on human body. There are so many symptoms in the pain of muscle. It's very various. for example, it is the cause of the liver, the spleen and a kidney function's weakening. the cause of the backbone subluxation, the cause of the shoulder joint and scapula, the cause of the sacrum and iliacjoint, the cause of hip joint and the cause of a sprain. In this thesis, we mainly deal with the method which the muscle and nervous system disease by fatigue and a sprain cure seat radiated by Original Infrared Rays and Magnatic force. then, Original Infrared Rays and Magnatic force pack up frapezius muscle, gluteus minimum muscle, gluteus medius muscle, gluteus maximus muscle, pririformis muscle around the spine. through this course the moral pressure by the nervous system disease can be treat.

• 비파괴검사학회지
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• 제31권5호
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• pp.472-478
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• 2011

본 연구의 목적은 소프트 골프 용구가 인체에 미치는 역학적 효과를 분석하는 것이다. 이를 위해 골프 스윙 동작을 캡처하여 스윙 모델을 생성하였고 시뮬레이션을 통해 손목, 팔꿈치, 어깨, 허리 관절의 토크를 도출하였다. 총 5명이 실험에 참여하였고 아연 합금 헤드의 소프트 골프 클럽과 기존 아이언 7번 클럽을 사용하였으며, 클럽당 5번씩 스윙을 수행하였다. 3대의 포지션 센서, 적외선 발광마커와 힘판을 사용하여 골프 스윙 동작을 캡처하였다. 인체 모델 생성 및 동역학 해석 프로그램을 통해 스윙 모델을 생성하여 시뮬레이션 하였고 관절의 토크를 도출하였다. 결과로 소프트 골프 클럽을 이용한 스윙에서 손목 관절 토크는 기존 골프 클럽을 이용한 스윙의 48.83 % 수준이며, 팔꿈치는 61.10 %, 어깨는 74.74 %, 허리는 102.46 %이다. 따라서 소프트 골프 클럽을 이용하여 스윙할 때, 기존 골프 클럽을 이용할 때보다 작은 힘으로 스윙 동작을 수행할 수 있기 때문에 관절에 부하가 적을 것이며, 관절 부상의 감소에 기여할 것이다.

• IMMUNE NETWORK
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• 제5권4호
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• pp.247-251
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• 2005

Background: Natural killer (NK) cells are CD3 (-) CD14 (-) CD56 (+) lymphocytes. They play an important role in the body's innate immune response. They can induce spontaneous killing of cancer cells or virus-infected cells via the Fas/Fas ligand or the granzyme/perforin systems. The corticotropin-releasing hormone (CRH) is an important regulator for the body's stress response. It promotes proliferation and migration of various cancer cells through the CRH type 1 receptor under stress, and also inhibits NK or T cell activity. However, the relationship of CRH and NK cell migration to the target has not been confirmed. Herein, we study the effect of CRH on NK cell migration. Methods: We used the human NK cell line, NK-92MI, and tested the expression of CRH receptor type 1 on NK-92MI by RT-PCR. This was to examine the effect of CRH on tumor and NK cell migration, thus NK cells (NK-92MI) were incubated with or without CRH and then each CRH treated cell's migration ability compared to that of the CRH untreated group. Results: We confirmed that CRH receptor type 1 is expressed in NK-92MI. CRH can decrease NK cell migration in a time-/dose-dependent manner. Conclusion: These data suggest CRH can inhibit NK cell migration to target cells.

• 한국운동역학회지
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• 제26권1호
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• pp.101-113
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• 2016

Objective: The purpose of this study was to investigate the effect of leg length discrepancy (LLD) on the human body during gait and standing posture. Methods: The study group comprised of 17 adult participants with LLDs of <1 cm. LLDs were artificially induced to 0, 1, 2, and 3 cm. The proportion of weight distribution, shift of the mean center of pressure, and Cobb's angle were measured in the standing position. Kinematic variables such as walking and striding width and time, and the proportion of stance phase for single- and double-limb gait were measured as well. The participants were required to either stand or walk on a treadmill (Zebris FDM) with a pressure plate, and the Cobb's angle measurements were obtained from radiographs. Results: A discrepancy of 3 cm in leg length resulted in a statistically significant shift of the center of pressure in the standing position. Moreover, the Cobb angle increased as the discrepancy became larger. The step length and width of the longer (left) leg during gait statistically significantly increased when the discrepancy was 2 cm. In addition, step time was statistically significant when the discrepancy between the longer (right) and shorter (left) legs was more than 2 cm. The proportion of single-limb stance phase was statistically significant as the discrepancy became larger, especially when the discrepancy was >2 cm for the longer (right) leg and 1 cm for the shorter (right) leg. Conclusion: The study showed that LLD influenced deformations of the human body and walking.