• Journal of the Korean Society for Precision Engineering
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• v.22 no.8 s.173
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• pp.57-63
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• 2005

Development of a locomotive mechanism fer the capsule type endoscopes will largely enhance the ability to diagnose disease of digestive organs. In connection with it, most of researches have focused on an installable locomotive mechanism in the capsule. In this paper, it is introduced that the movement of a capsule type endoscope in digestive organ can be manipulated by magnetic force produced outside human body. Since the magnetic force is provided by permanent magnets, no additional power supply to the capsule is required. Using a robotic manipulator for locating the external magnet, the capsule motion control system can cover the whole human digestive organs. This study is particularly concentrated on dither motion effect to improve the mobility of capsule type endoscope. It was experimentally found out that the friction coefficient between the capsule and digestive organ can be remarkably reduced by superposing yawing or rolling dither motion on the translatory motion. In this paper, the experimental results obtained with the direction, amplitude and frequency of sinusoidal dither motion changed is reported.

• Journal of Korean Medical classics
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• v.19 no.1 s.32
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• pp.128-136
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• 2006

This study is on Yoshimasu Todo's thought of medicines. Conclusions are as below. Medicines are poisons. Therefore, they don't have the ability to restore the vital energy. Medicine-processing(法製) can only be done for doubling the toxicity, since the poison itself is the very effect of a medicine. One poison has an ability to treat only one main symptom. If the poison strikes the main symptom right, it doesn't harm the human body. Since warm-heat-cool-cold(溫熱凉寒) of a medicine can't be known by human ability, it can't be used as the standard of judgment when selecting a medicine.

• Biomolecules & Therapeutics
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• v.6 no.3
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• pp.317-327
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• 1998

The subchronic toxicity study of rHuEPO, a newly developed recombinant erythropoietin, was investigated for 13 weeks in Beagle dogs intravenously treated with doses of 100, 500 and 2,500 lU/kg/day. There were no significant changes in body weight, food intake, physical and opthalmic examination, urine analysis, etc. Any toxic response was not observed except for enlarged spleen and extramedullary hematopoiesis. These results indicate that the no-observed adverse effect level (NOAEL) of rHuEPO is 100 lU/kg in Beagle dogs.

• Food Science and Biotechnology
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• v.15 no.1
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• pp.158-161
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• 2006

This study was designed to determine possible weight loss effects of Hangbisan, an oriental medicine, on Sprague-Dawley (SD) rats. SD rats that were fed a high-fat diet for 6 weeks to induce obesity and subsequently fed with a basic diet containing 10%(w/w) Hangbisan or 10%(w/w) cellulose for 8 weeks. The Hangbisan fed rats demonstrated a significantly (p<0.05) reduced weight gain compared to the cellulose fed rats as well as a reduced level of plasma cholesterol and triglycerides and an increased level of (HDL)-cholesterol. These results suggest that dietary Hangbisan has an anti-obesity effect in the high-fat diet-induced obesity (DIG) rat and therefore a potential use as an anti-obesity agent in the application of oriental medicine compounds.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.21 no.45
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• pp.333-346
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• 1998

By progress of technology, it became possible for us to do many kinds of operations in virtual environment. However side effect is called simulator sickness may occur to human body when human come in contact with this new environment. It makes symptoms similar to motion sickness. Many studies about that were started in 1950s and have actively been progressing in other countries, but in Korea recognition about that field is insufficient. Main contribution of this paper would be the base study about phenomena of simulator sickness which may be occurs in simulator or virtual reality environment, factors which induce simulator sickness, and quantifying methods of simulator sickness.

• Journal of IKEEE
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• v.12 no.4
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• pp.185-195
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• 2008

In this paper, PIFA(Planar Inverted F Antenna) which operates in PCS(Personal Communication System) band is designed and characteristics are investigated. Designed PIFA was installed in three types of handsets, folder, bar, slide, and the performance was evaluated. Head and hand phantom were added to make the most similar environment to real condition of mobile phone use, and influences on antenna performance were analyzed. The simulation results confirm radiation patterns are greatly changed and antenna efficiency is decreased by the effect of human body. Performance variation of the mobile handset antenna was observed as changing the angle between mobile handset and head phantom from $0^{\circ}$ to $2^{\circ},\;4^{\circ}$ to confirm the variation caused by the relative position of mobile handset and head phantom. Directivity was decreased gradually as the antenna goes away from head phantom, and showed the trend of increasing efficiency. But in the case of bar type, where the position of antenna is relatively close to head phantom, that trend didn't show. It was confirmed that the shape of handset has a great effect on the performance.

• Proceedings of the Society of Korea Industrial and System Engineering Conference
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• 2002.05a
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• pp.243-257
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• 2002

A study on processing for producing cure seat radiated by Original Infrared Rays and Magnatic force. We are well aware that Original Infrared Rays and Magnatic force influence on our human body benificially. In the technical background of this research product, we treated that the product has some operations of ceramic hardwood charcoal, far infrared rays and magnetic, so it can serve large part curative values made of far infrared rays and magnetic force of ceramics. Also, in the special quality of the product deal with ceramic, hard charcoal, ferrite, gelatin what is needed in production. And among them, ferrite, ceramic and hard charcoal are introduced by the manufacturing process of the moleculeization. In concluding, this study described the manufacturing process on the basis of the worksheets and arranged the useful effect which effect on human body. There are so many symptoms in the pain of muscle. It's very various. for example, it is the cause of the liver, the spleen and a kidney function's weakening. the cause of the backbone subluxation, the cause of the shoulder joint and scapula, the cause of the sacrum and iliacjoint, the cause of hip joint and the cause of a sprain. In this thesis, we mainly deal with the method which the muscle and nervous system disease by fatigue and a sprain cure seat radiated by Original Infrared Rays and Magnatic force. then, Original Infrared Rays and Magnatic force pack up frapezius muscle, gluteus minimum muscle, gluteus medius muscle, gluteus maximus muscle, pririformis muscle around the spine. through this course the moral pressure by the nervous system disease can be treat.

• Journal of the Korean Society for Nondestructive Testing
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• v.31 no.5
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• pp.472-478
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• 2011

The purpose of this study was to analyze the kinetic effect of Soft-$golf^{TM}$ instrument on the human body structure. To analyze the kinetic effect of Soft-$golf^{TM}$ instrument, Golf swing using Soft-$golf^{TM}$ instrument and regular golf instrument was captured. And then Upper limbs and lumbar joint torques was calculated via computer simulation. Five man participated this study. Subjects performed golf swing using a regular golf and Soft-$golf^{TM}$ instrument. Golf swing motion was captured using three position sensor, active infrared LED maker and force plate. Golf swing model was generated and simulated using ADAMS/LifeMOD program. As a results, joint torque during Soft-golf swing were lower than regular golf swing. Thus soft-golf swing have joint load lower than regular golf swing and contribute to reduce joint injury.

• IMMUNE NETWORK
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• v.5 no.4
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• pp.247-251
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• 2005

Background: Natural killer (NK) cells are CD3 (-) CD14 (-) CD56 (+) lymphocytes. They play an important role in the body's innate immune response. They can induce spontaneous killing of cancer cells or virus-infected cells via the Fas/Fas ligand or the granzyme/perforin systems. The corticotropin-releasing hormone (CRH) is an important regulator for the body's stress response. It promotes proliferation and migration of various cancer cells through the CRH type 1 receptor under stress, and also inhibits NK or T cell activity. However, the relationship of CRH and NK cell migration to the target has not been confirmed. Herein, we study the effect of CRH on NK cell migration. Methods: We used the human NK cell line, NK-92MI, and tested the expression of CRH receptor type 1 on NK-92MI by RT-PCR. This was to examine the effect of CRH on tumor and NK cell migration, thus NK cells (NK-92MI) were incubated with or without CRH and then each CRH treated cell's migration ability compared to that of the CRH untreated group. Results: We confirmed that CRH receptor type 1 is expressed in NK-92MI. CRH can decrease NK cell migration in a time-/dose-dependent manner. Conclusion: These data suggest CRH can inhibit NK cell migration to target cells.

• Korean Journal of Applied Biomechanics
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• v.26 no.1
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• pp.101-113
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• 2016

Objective: The purpose of this study was to investigate the effect of leg length discrepancy (LLD) on the human body during gait and standing posture. Methods: The study group comprised of 17 adult participants with LLDs of <1 cm. LLDs were artificially induced to 0, 1, 2, and 3 cm. The proportion of weight distribution, shift of the mean center of pressure, and Cobb's angle were measured in the standing position. Kinematic variables such as walking and striding width and time, and the proportion of stance phase for single- and double-limb gait were measured as well. The participants were required to either stand or walk on a treadmill (Zebris FDM) with a pressure plate, and the Cobb's angle measurements were obtained from radiographs. Results: A discrepancy of 3 cm in leg length resulted in a statistically significant shift of the center of pressure in the standing position. Moreover, the Cobb angle increased as the discrepancy became larger. The step length and width of the longer (left) leg during gait statistically significantly increased when the discrepancy was 2 cm. In addition, step time was statistically significant when the discrepancy between the longer (right) and shorter (left) legs was more than 2 cm. The proportion of single-limb stance phase was statistically significant as the discrepancy became larger, especially when the discrepancy was >2 cm for the longer (right) leg and 1 cm for the shorter (right) leg. Conclusion: The study showed that LLD influenced deformations of the human body and walking.