• Journal of Periodontal and Implant Science
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• v.30 no.1
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• pp.77-91
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• 2000

The purpose of this study was performed to evaluate the effect of Armeniacae Semen extracts on human gingival fibroblasts and periodontal ligament cells in vitro. A experiment was done to evaluate the effect of Armeniacae Semen extracts in high glucose media. $400mg/d{\ell}$ glucose was added to the culture media of all groups. In control group, the cells($4.5{\times}10^4cells/ml$) were cultured with Dulbecco's Modified Eagle's Medium contained with 10% fetal bovine serum. In experimental groups, Armeniacae Semen extracts was added to the above culture media at the final concentrations of $1{\mu}g/m{\ell}$(Test group 1) and $l0{\mu}g/m{\ell}$(Test group 2). Then each group was tested for the rate of cell proliferation at 1, 2, 5 days, protein levels at 2, 5 days, and alkaline phosphatase activity at 2, 5 days. The results were as follows ; 1. Under the high glucose condition 1)As centration of Armeniacae Semen extracts increased, the rate of cell proliferation decreased significantly in test group 2 at 5 days in human gingival fibroblasts, but increased significantly in test group 2 at 5 days in human periodontal ligament cells(P<0.05). 2)In human gingival fibroblasts, test group 2 showed significantly decreased protein levels as compared to control group at 5 days. In periodontal ligament cells, test group 1 and 2 showed not significantly increased protein levels as compared to control group at 2, 5 days(P<0.05). 3)Alkaline phosphatase activity of human periodontal ligament cells increased as concentration of Armeniacae Semen extracts increased. The test group 1and 2 showed significant increase as compared to control group at 5 days(P<0.05). From the above results, Armeniacae Semen extracts appeared to enhance cellular activities including the rate of cell proliferation, protein levels and alkaline phosphatase activity of selectively human periodontal ligament cells in high glucose media. This study suggests that Armeniacae Semen extracts seem to be able to subside the inflammation of periodontal tissue and regenerate the destructed periodontal tissue.

• Proceedings of the ESK Conference
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• 1998.04a
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• pp.167-172
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• 1998

Methods of evaluating the physiological activity of the living body are EEG, EOG, Heart rate, and Rectal temperature, etc. In the study of Hagiwara and Araki(1993), they found positive correlations among performance test, physiological measurement, and subjective feeling measurement. Human alertness of pilot directly influences on the flight performance that accomplishes a lot of vigilance task and procedure execution in flight. Accordingly, this paper deals with the quantitative and objective performance test based on tracking error and reaction time by means of the new computer test program into which the perception-motion system of human beings is applies. Throughout this experiment using performance thst, the results suggest that performance capability in state of sleep deprivation 2 hours and alcoholic 0.05 .apaprox. 0.06% in blood were more impaired than one in a normal state, and they further showed statistically significant differences between them, which were influenced by impairment factors of body regulation and pilot's grade. We also obtained the prediction value and the 95% confidence interval of tracking error and reaction time at the normal state for the purpose of distinguishing performance capability between the normal state and the abnormal state. And it is ecpected that the evaluation of human alertness using performance test will be applied to the quantitative assessment of an each pilot's realistic consciousness/attention, and will lead a flight commander to the accurate decision of mission approval prior to a flight.

• Toxicological Research
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• v.13 no.3
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• pp.303-306
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• 1997

Antigenic potential of genetically engineered human granulocyte colony-stimulating factor (CJ-50001) was assessed in guinea pigs and mice. In active systemic anaphylaxis (ASA) test, although CJ-50001 at 50 $\mu\textrm{g}$ /head induced anaphylactic responses, CJ-50001 5 $\mu\textrm{g}$ /head alone or 50 $\mu\textrm{g}$ / head with adjuvant did not induce anaphylactic responses. In passive systemic anaphylaxis test (PCA) or passive hemagglutination test (PHA), CJ-50001 did not induce positive responses. It is concluded that, in light of the fact that CJ-50001 was antigenic only in ASA but not in PCA or PHA and also that CJ-50001 is a foreign human recombinant protein to guinea pigs, CJ-50001 may not induce systemic allergic react-ion in its clinical use in human.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.10
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• pp.391-399
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• 2020

This study aims to analyze the relationship of e-HRM implementation to employee performance both directly and indirectly through the intervening of the Human Resource service Quality variable, both practically and theoretically. This study uses variance-based structural equation modeling (SEM) techniques with partial least square (PLS) statistical testing tools to test the direct relationship of e-HRM and the performance and relationship moderated by Human Resources service quality tested on 200 civil servants in five offices under the coordination of the Government of the South Sulawesi Province of Indonesia. The data collection model in this study uses an online survey. The data analysis stages through the explanatory concept consist of, first, the interpretation of the distribution of the average frequency of respondents' answers; second, outer-loading; third, determination of the validity and reliability; fourth, the coefficient of determination test and partial test; fifth, the GoF model; sixth, validity test; and seventh, hypothesis testing. This study explores four hypotheses in a comprehensive fashion; the results of this study show that all hypotheses have positive and significant effects both through direct and intervening relationships. Among the three direct relationships, the relationship of e-HRM variables on HR Service Quality is greatest and most dominant.

• Journal of Korean Home Economics Education Association
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• v.9 no.2
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• pp.47-67
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• 1997

The purpose of this study was to investigate the middle school students’and their parent’s perception of the 6th Home Economics Education curriculum, their learning satisfaction, and the students’s perceived learning effect, focusing on the areas of human development and family relations. The subjects of this study were 392 middle school students, their parents and 51 Home Economics teachers in Pohang and Seoul. Data were analyzed by frequency, percentage, test, F test, pearson’s product correlation coefficient, and $\chi$(sup)2 test, Schff post hoc test using the SAS computer program. The result of this study were that (1) the middle school student’s and their parent’s perception of the 6th Home Economics Education Curriculum, in general, was very positive. (2) Students, teachers and parents showed high levels of learning satisfaction with the areas of human development and family relations. (3) Student’s perceived learning effect on the areas of human development and family relations was considerably high.

• Journal of Families and Better Life
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• v.6 no.1
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• pp.95-116
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• 1988

this study has dual purposes; one is to develope a new theoretical framework in consumer behavior area by applying the human ecological approach, and the other is to test the theory empirically area by applying the human ecological approach, and the other is to test the theory empirically by examining prepurchasing behavior of housing. Research methods adopted in this study are library search and survey research with self-administered questionnaires. The statistical methods used in the survey research are factor analysis, chi square test, and multivariate analysis with crosstablulations. According to the human ecological approach, ecological environments are important sources of consumer needs which , in turn, are satisfied by purchasing behavior in the market. Within this theoretical framework, consumers con improve the quality to life by perceving clearly what their needs are thereby making the most possible efficient purchasing decision making. The major findings of the empirical research on the basis of the theoretical framework are as follows; 1) Housing needs significantly vary with different ecological environment. 2) consumer information search behavior does not differ significantly by housing needs. 3) Housing needs turn out to be an intervening variable between ecological environments and consumer information search behavior. the results of this study show that the human ecological approach is useful in consumer behavior studies. The empirical result that consumer needs are not significantly satisfied by consumer behavior suggests a now direction in consumer education.

• Parasites, Hosts and Diseases
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• v.59 no.3
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• pp.257-263
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• 2021

Human gnathostomiasis is a parasitic disease caused by Gnathostoma nematode infection. A rapid, reliable, and practical immunoassay, named dot immuno-gold filtration assay (DIGFA), was developed to supporting clinical diagnosis of gnathostomiasis. The practical tool detected anti-Gnathostoma-specific IgG4 in human serum using crude extract of third-stage larvae as antigen. The result of the test was shown by anti-human IgG4 monoclonal antibody conjugated colloidal gold. The sensitivity and specificity of the test were both 100% for detection in human sera from patients with gnathostomiasis (13/13) and from healthy negative controls (50/50), respectively. Cross-reactivity with heterogonous serum samples from patients with other helminthiases ranged from 0 (trichinosis, paragonimiasis, clonorchiasis, schistosomiasis, and cysticercosis) to 25.0% (sparganosis), with an average of 6.3% (7/112). Moreover, specific IgG4 antibodies diminished at 6 months after treatment. This study showed that DIGFA for the detection of specific IgG4 in human sera could be a promising tool for the diagnosis of gnathostomiasis and useful for evaluating therapeutic effects.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2063-2068
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• 2012

Aim: Liquid-based cytology is the most often used method for cervical cancer screening, but it is relatively insensitive and frequently gives equivocal results. Used as a complementary procedure, the high-risk human papillomavirus (HPV) DNA test is highly sensitive but not very specific. The human telomerase RNA gene (TERC) is the most often amplified oncogene that is observed in cervical precancerous lesions. We assessed genomic amplification of TERC in liquid-based cytological specimens to explore the optimal strategy of using this for cervical cancer screening. Methods: Six hundred and seventy-one residual cytological specimens were obtained from outpatients aged 25 to 64 years. The specimens were evaluated by the Digene Hybrid Capture 2 (HC2) HPV DNA test and fluorescence in situ hybridization (FISH) with a chromosome probe to TERC (3q26). Colposcopic examination and histological evaluation were performed where indicated. Results: The TERC positive rate was higher in the CIN2+ (CIN2, CIN3 and SCC) group than in the normal and CIN 1 groups (90.0% vs. 10.4%, p < 0.01). In comparison with the HC2 HPV DNA test, the TERC amplification test had lower sensitivity but higher specificity (90.0% vs. 100.0%, 89.6% vs. 44.0%, respectively). TERC amplification test used in conjunction with the HC2 HPV DNA test showed a combination of 90.0% sensitivity and 92.2% specificity. Conclusion: The TERC amplification test can be used to diagnose cervical precancerous lesions. TERC and HPV DNA co-testing shows an optimal combination of sensitivity and specificity for cervical cancer screening.

• Journal of Digital Convergence
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• v.17 no.9
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• pp.291-299
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• 2019

This study is a nonequivalent control group pretest-posttest designed to understand the effect of ethical dilemma discussion program on human rights sensitivity and ethical values of university students. By providing ethical dilemma discussion program to university students in C university, G-do, the effectiveness was verified. Analyzed using IBM SPSS 24.0. The normality of the variables was verified by Shapiro-Wilk test. Homogeneity was verified using real number and percentage, Fisher's exact probability test and independent t-test. The program's effect was verified using paired t-test. The results of this study are as follows: after the ethical dilemma discussion program, the experimental group's human rights sensitivity(t=-2.32, p=.025), and ethical value(t=-2.43, p=.020) were higher than the control group. Therefore, the ethical dilemma discussion program of this study helped improve the human rights susceptibility and ethical values of the subjects. Further research is needed to verify the effects of ethics education on diverse groups.

• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.4
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• pp.291-301
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• 2015

This study compared the in vitro cell viability and differentiation potentials of human deciduous dental pulp cells (DPCs) on mineral trioxide aggregate (MTA)-like products (ProRoot MTA, RetroMTA and Endocem Zr). The experimental materials were prepared as circular discs, which were used to test the effects of the materials on the viability of human DPCs when placed in direct and indirect contact. Furthermore, the pH of the extracted materials was recorded, and their effect on cell differentiation potential was evaluated by evaluating the alkaline phosphatase (ALP) activity and Alizarin Red S staining of DPCs incubated with the test materials. In direct contact, the cell viability of human DPCs was higher with ProRoot MTA and RetroMTA than with Endocem Zr. However, when in indirect contact, the cell viability of human DPCs was generally higher in Endocem Zr than in ProRoot MTA and Retro MTA. With respect to pH, the alkalinity was lower for Endocem Zr than for the other test materials. The ALP activities of the cells were not enhanced by any of the experimental materials. Alizarin Red S staining of the tested human DPCs revealed that their differentiation potential was lower than for cells incubated with osteogenic induction medium. While there were differences in the responses of the human DPCs to the test materials, all displayed degrees of cytotoxicity and were unable to enhance either the viability or differentiation of human DPCs. However, Endocem Zr exhibited better cell viability and was less alkaline than the other test materials.