• Nutrition Research and Practice
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• v.18 no.1
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• pp.110-118
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• 2024

BACKGROUND/OBJECTIVES: Depression and anxiety are common mental health problems. Anthocyanins from berries might have an inhibitory effect on monoamine oxidase (MAO) enzymes and alleviate various mood and anxiety symptoms. This study examined the effects of a daily supplement of an anthocyanin-rich product on mental health problems. SUBJECTS/METHODS: This study was a secondary analysis from a randomized, 6-week, open-label trial in 300 healthy participants aged 18-60 years who consumed 1 or 2 servings of anthocyanin-rich mulberry milk daily. The General Health Questionnaire-28 (GHQ-28) and Hospital Anxiety and Depression Scale (HADS) were used to monitor mental health problems. In addition, the saliva activity levels of MAO-A, MAO-B, and cortisol were examined at the baseline and after 6 weeks. RESULTS: The total scores of the GHQ-28 and HADS and all their subscales decreased in both groups (all P < 0.05). The cortisol, MAO-A, and MAO-B activities decreased significantly (all P < 0.05), but there were no significant differences between the groups (all P > 0.05). Significant correlations were noted between the decreased activity level of MAO-A enzyme and decreased scores from the GHQ-28 somatic subscale and the HADS depression subscale (all P < 0.05). CONCLUSIONS: Daily consumption of anthocyanin-rich mulberry milk possibly improves mental health problems by reducing depressive and anxiety symptoms in the working population. The suppression of MAO-A activity is a possible underlying mechanism.

• Journal of Korea Multimedia Society
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• v.25 no.2
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• pp.374-381
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• 2022

This study analyzes the visual perceptual difference of observers in the artworks created by human artists and artificial intelligence(AI) through eye-tracking. More specifically, the study analyzes the degree of visual attention through a fixation experiment on non-linguistic sources such as the formation and expression of artworks. As a result of this study, the subjects had guessed that one out of four artworks were created by AI (in actuality, 61.1% of the artworks were created by The Next Rembrandt). This demonstrates that most of the subjects hardly recognized the difference between the artwork of human artists and AI. From the comparative analysis of visual perceptual differences found through eye-tracking, more visual attention was found to be demanded for catching details of more stimulating visuals compared to less stimulating visuals. In the gender difference analysis, both of the female and male subjects were likely to stare more intently at the flowers of still-life paintings (Deep Dream & Vincent Van Gogh) while the eyes of a portrait painting (Rembrandt & The Next Rembrandt); this demonstrates no significant differences in gender. Various opinions on AI and art creation from different perspectives arose, therefore, this research is meaningful in a way that it suggests an objective examination through experiments with an artistic perspective.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.25 no.3
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• pp.338-345
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• 2015

Objectives: The objective of this study was to evaluate the distribution of urine cadmium levels of residents in the surrounding areas of an industrial complex. Methods: During the period of three month from August to October 2012, informed consent was obtained from a total of 362 residents in Kwangyang and Yeosu. We collected urine sample from all subjects and their demographic characteristics, including alcohol drinks and smoking habits, using a questionnaire. The urine samples were analyzed using atomic absorption spectrometer. Results: The urinary cadmium geometric mean concentration of total participants was $0.87{\mu}g/g\;cr$. The results of this study showed that higher urine cadmium levels were observed in females and some subjects with a higher level of education level and a lower BMI. Also, those subjects who preferred to take vegetables and took fish 3 days before urine sampling procedure revealed higher urine cadmium concentrations. The urine cadmium concentrations of subjects in the exposed area($0.91{\mu}g/g\;cr$) were significantly higher than those in the control area($0.78{\mu}g/g\;cr$). Conclusions: An additional study is needed to assess health risks of residents in the vicinity of environment-unfriendly areas, coupled with endeavors to examine possible heavy metals contamination factors that may affect the human body.

• International Journal of Automotive Technology
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• v.7 no.5
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• pp.625-635
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• 2006

From a viewpoint of human factors, automated highway systems(AHS) can be defined as one of the newly developing human-machine systems that consist of humans(drivers and operators), machines(vehicles and facilities), and environments(roads and roadside environments). AHS will require a changed vehicle control process and driver-vehicle interface(DVI) comparing with conventional driving. This study introduces a fixed-based AHS simulator and provides questionnaire-based human factors evaluation results after three kinds of automated driving speed experiences in terms of road configuration, operation policies, information devices, and overall AHS use. In the simulator, the "shared space-at-grade" concept-based road configuration was virtually implemented on a portion of the Kyungbu highway in Korea, and heads-up display(HUD), AHS information display, and variable message signs(VMS) were installed for appropriate AHS DVI implementation. As the results, the subjects expressed positive opinions on the implemented road configuration, operation policies, and the overall use of AHS. The results of this study would be helpful in developing the road configuration and DVI design guideline as the basic human factors research for the future implementation of AHS.

• Asian Oncology Nursing
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• v.8 no.1
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• pp.61-66
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• 2008

Purpose: Purpose of study was to analyze the research articles in the Journal of Korean Oncology Nursing in order to provide an direction for the future research, Methods: This study analyzed 93 studies published in the Journal of Korean Oncology Nursing, from its beginning year to the year 2007, according to the research objectives. The frame of evaluation included years and types of publication, the theoretical frameworks, research design, subject, data collection method, keyword analysis by MeSH. Results: 45.2% of studies was non-degree based studies. 95.7% of studies was not described theoretical framework in the articles. 71.0% was utilized a non-experimental design. 57% of subjects in researches was patients. 76.3% of studies were used the questionnaire for data collection. Concepts as human, nursing, and health were consistently appeared in research. But concepts of environment has been insufficiently conducted. Conclusion: Researches in the Journal of Korean Oncology Nursing has been changed in methodology and the topics of research for the last 7 yr. It progresses in both quantity and quality. But, it is necessary to conduct research founded on theoretical background, various research design, variability of study subjects and topics as supported by scientifically and empirically.

• Proceedings of the Korea Contents Association Conference
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• 2009.05a
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• pp.943-948
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• 2009

In the research of HCI (Human-Computer Interaction), we always use the GUI（graphical user interface） of graphics input devices until we invent TUI (tangible user interface) which is used to control the computer by hand-touching or other subjects. In this study, we investigate and classify several TUI for the most part in business with the theory and concept of Tangible Bits by Hiroshi Ishii & Brygg Ullmer in order to research the development of TUI.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.47 no.4
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• pp.1-10
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• 2010

This present paper's goal is to show a virtual human agent's movement-data loci based on realistically limited perception data is human-like. To determine human-likeness of the movement-data loci, we consider interactions between two parameters: Realistically Limited Perception (RLP) data and Incremental Movement-Path data Generation (IMPG). That is to consider how the former (i.e., RLP), one of the simulated parameters of human thought or its elements dictates the latter (i.e., IMPG), one of the simulated parameters of human movement behavior. Mapping DB is a prerequisite for navigation in an agent system because it functions as an interface between perception and movement behavior. Although Hill et al. studied mapping DB methodology based on RLP, their research dealt only with a rendering camera's view point data. The agent system in this present paper was integrated with the Hill's mapping DB module and then the two parameters' interaction was considered on a military reconnaissance mission with unexpected enemy emergence. Movement loci that were generated by the agent and subjects were compared with each other. The agent system in this present research verifies that it can be a functional test bed for producing human-like movement-data loci although the human-likeness of agent is the result of a pilot test, determined by two parameters (RLP and IMPG) and only 30 subjects.

• The Journal of KAIRB
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• v.2 no.2
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• pp.33-36
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• 2020

In December 2019, coronavirus disease 2019 (COVID-19) was discovered in Wuhan, China. The disease was so severe that as early as 30 January 2020 COVID-19 was declared by WHO as a Public Health Emergency of International Concern. There have been a lot of concerns about conducting COVID-19 clinical researches scientifically and ethically in pandemic. This article is directed at addressing these issues from the perspective of IRB. First of all, the urgency of COVID-19 research requires prompt IRB process through efficient ethics review and oversight system. IRB should determine whether the risks that will be presented to human subjects are justified after assessing possible harm and anticipated benefits. The safety of subjects should not be compromised. Furthermore, informed consent should be voluntarily obtained by sufficient information in consideration of special circumstances during a pandemic.

• The Journal of Internal Korean Medicine
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• v.31 no.4
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• pp.752-762
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• 2010

Objective : In the present study, we investigated genetic distribution of eight single nucleotide polymorphisms of PON1 between Dampness and Phlegm and non Dampness and Phlegm pattern identification(PI) among Korean stroke patients. Materials and Methods : One hundred forty stroke subject without Dampness and Phlegm and fifty eight stroke subjects with Dampness and Phlegm were participated in this study. After informed consents, eight single nucleotide polymorphisms(SNPs) in PON1 of each subjects were identified by DNA sequencing and primer extension method and statistical analysis was performed to determine the significant difference between Dampness and Phlegm and non Dampness and Phlegm groups. Results : Among anthropometric characteristics and blood parameters, waist circumference and total cholesterol were significantly higher in Dampness and Phlegm. Among 8 SNPs of PON1, frequency of M allele and subjects with M allele in L55M SNP were significantly higher in Dampness and Phlegm group (p=0.0032 and p=0.0053, respectively) but subjects with T allele in C-2033T SNP were lower in Dampness and Phlegm group(p=0.0302). Effect of L55M and C-2033T on Dampness and Phlegm were 3.07% and 1.75%, respectively. Conclusion : Our results suggest that L55M SNP in exon and C-2033T in promoter region of PON1 maybe affect to Dampness and Phlegm pattern identification. However, further study should be carried out to find out the detailed mechanism how L55M and C-2033T can affect Dampness and Phlegm stroke patients.

• Journal of Nutrition and Health
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• v.44 no.6
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• pp.551-561
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• 2011

Given that household food security issues have become the concern of the Korean society, this study aimed to develop food security measures for the Korean population. Based on the literature reviews on previously developed food security measures, the 18-item US household food security survey module (US HFSSM) was adapted. The developed food security measures was assessed by qualitative validity method. It was evaluated and modified by face validity by expert focus groups belong to university, public health center, and government agencies and by cognitive interview by 40 subjects with low household income who live in an urban community and are participants in welfare programs of local districts. Then, it was reviewed and revised by the National Institute of the Korean Language and the advisory committee for nutrition survey of Korean National Health and Nutrition Examination Survey (KNHANES). The results showed that the developed questionnaire items were well adapted by expert focus groups and general subjects, showing the feasibility of measuring food security with the developed measures although there were discrepancies in some expressions of questionnaire items between experts focus groups and general subjects. The study to assess reliability and quantitative validity of the developed food security measures should be further needed to examine its application for KNHANES.