• International Journal of Stem Cells
• /
• v.16 no.1
• /
• pp.16-26
• /
• 2023

Despite long-term research achievements, the development of cell therapy (CT) products remains challenging. This is because the risks experienced by the subject and therapeutic effects in the clinical trial stage are unclear due to the various uncertainties of CT when administered to humans. Nevertheless, as autologous cell products for systemic administration have recently been approved for marketing, CT product development is accelerating, particularly in the field of unmet medical needs. The human experience of CT remains insufficient compared with other classes of pharmaceuticals, while there are countless products for clinical development. Therefore, for many sponsors, understanding the rationale of human application of an investigational product based on the consensus and improving the ability to apply it appropriately for CT are necessary. Thus, defining the level of evidence for safety and efficacy fundamentally required for initiating the clinical development and preparing it using a reliable method for CT. Furthermore, the expertise should be strengthened in the design of the first-in-human trial, such as the starting dose and dose-escalation plan, based on a sufficiently acceptable rationale. Cultivating development professionals with these skills will increase the opportunity for more candidates to enter the clinical development phase.

• The Korean Journal of Franchise Management
• /
• v.10 no.2
• /
• pp.33-47
• /
• 2019

Purpose - The purpose of this study is to classify and analyze existing studies from various angles through systematic literature review of how human resources development has been researched in the domestic franchise business. These studies are intended to suggest the direction in which human resource development research should be conducted in the future in the franchise business. Research design, data, and methodology - This study is based on systematic literature review methodology. It has gone through the process of subject language setting, literature search routing, search term selection, literature selection, literature classification and literature analysis. The systematic literature review identified 59 peer-reviewed dissertations and scientific journal publications on the subject of HRD in Korea franchise business. Result - This study analyzed by research methods, research industries, research population and dependent variable using the systematic review process. The literature studied in the 2000s mainly led to research on education and training of franchise employees in beauty franchise business. In the literature studied since 2010, human resources development was mainly studied in the supervisor in the restaurant franchise business, and in the study of competence rather than education and training. According to the research methods, statistical methods were mostly relatively simple, such as t-test or one-way distribution analysis until the 2000s, and after 2010, in-depth and structural studies using multiple return analysis, structural method analysis, path analysis, multi-dimensional scale analysis, AHP, etc were conducted. When classified by study dependant, early research until the 2000s focused on the study of education and training, which is an independent variable, on the satisfaction of education programs, job satisfaction, and immersion. On the other hand, studies conducted since 2010 have produced more complex results using various medium variants, and those related to management performance and relationship performance have been mainly studied, rather than the satisfaction of the education itself. Conclusions - While the domestic franchise business is expanding in terms of quantity, such as the number of franchises and franchises, the development in terms of quality for the joint growth of franchises and franchisees is still lacking. In order for the franchisee to continue to grow with each other, the franchisee must identify and develop their current performance or expected capabilities through capacity modeling at various targets and levels.

• Journal of the Korean Society for information Management
• /
• v.29 no.4
• /
• pp.123-142
• /
• 2012

To develop an intelligent search engine to help users retrieve information effectively, various methods, such as Semantic Web, have been used, An effective retrieval method of such methods uses ontology technology. In this paper, we built National R&D ontology after analyzing National R&D Information in NTIS and then implemented National R&D Knowledge Map to represent and retrieve information of the relationship between object and subject (project, human information, organization, research result) in R&D Ontology. In the National R&D Knowledge Map, center-node is the object selected by users, node is subject, subject's sub-node is user's favorite query in National R&D ontology after analyzing the relationship between object and subject. When a user selects sub-node, the system displays the results from inference engine after making query by SPARQL in National R&D ontology.

• Journal of Korean Library and Information Science Society
• /
• v.48 no.4
• /
• pp.21-47
• /
• 2017

This study aims to analyze features of topics about AI(Artificial Intelligence) which is gaining a massive attention these days. Newspaper articles published from 2016 to June, 2017 were selected to analyze key subjects. The reason why the period was selected is people started to get attention on AI since 2016 as AlphaGo came out and gave a shock. The number of coded main message was 1,210 in 525 newspaper articles in total. The messages were categorized as three subject categories: the seven major categories, 62 middle categories. and minor categories. The seven major categories contains issues such as AI research, AI application, AI business, AI era, AI argument, AlphaGo, and other topics. The first features of issues about AI found in the major subject categories is that they are various and complicate. Second, it is important that social and policy-level issues related AI, such as job losses, misuse, and error should be dealt with to utilize AI safely. Last, issues related the role of human and revolution of education system in the AI era were shown as subjects which are important but hard to discuss.

• Journal of the Ergonomics Society of Korea
• /
• v.30 no.5
• /
• pp.651-657
• /
• 2011

Objective: The aim of this study is to investigate the system to integrate and manage the in-vehicle interactions between the drivers and the in-vehicle mobile IT devices. Background: As the mobile IT technology is being used anywhere, the drivers are interacting with the mobile IT device on driving situations. The distraction of the driver's attention causes the car accidents. It is necessary to develop the HVI(Human Vehicle Interface System) to integrate and manage the in-vehicle interactions with IT devices. Method: The HVI System is designed not as the interfacing subject but as the supervising system to monitor the driver's status and support the driver to concentrate on the primary tasks. The HVI system collects the status information of the car and driver and estimate the driving workload. Results: The HVI system controls how to provide the output information based on the driving workload. We implemented the HVI system prototype and applied in the real vehicle with the HVI cell phone and the HVI car navigation system. Conclusion: Depending on the driving situations, the HVI system prevented the information output in dangerous situation and diversified the modality and the intensity of the output information. Application: We will extend the HVI system to be connected the other various IT devices and verity the effectiveness of the system through various experiments.

• Journal of the Korea Society of Computer and Information
• /
• v.25 no.1
• /
• pp.55-61
• /
• 2020

With the development of deep learning technology and advances in computing power, video-based research is now gaining more and more attention. Video data contains a large amount of temporal and spatial information, which is the biggest difference compared with image data. It has a larger amount of data. It has attracted intense attention in computer vision. Among them, motion recognition is one of the research focuses. However, the action recognition of human in the video is extremely complex and challenging subject. Based on many research in human beings, we have found that artificial intelligence-like attention mechanisms are an efficient model for cognition. This efficient model is ideal for processing image information and complex continuous video information. We introduce this attention mechanism into video action recognition, paying attention to human actions in video and effectively improving recognition efficiency. In this paper, we propose a new 3D residual attention network using convolutional neural network based on two attention models to identify human action behavior in the video. An evaluation result of our model showed up to 90.7% accuracy.

• Hwankyungkyoyuk
• /
• v.17 no.2
• /
• pp.106-121
• /
• 2004

This thesis examined and analyzed the occupational status of the promising occupations in the environmental industry. A study on the status of the occupations in the environmental industry is very necessary for planning policies and improving occupations in the environmental industry. Studies and discussions regarding the status of the occupations in the environmental industry, however, were extremely insufficient. A survey of the employees in the environmental industry was conducted in order to certainly comprehend the status of the occupations, educational and training programs, and occupational changes and to utilize the result of the survey as foundational data necessary for occupational studies in the environmental industry. The subject of the survey was limited to the employees who had work for one or more years in twenty promising occupations in the environmental industry. The content of the survey was occupational performance competencies, occupational careers, the degree of occupational satisfaction, vocational education and training, working conditions, occupational changes, and the security of the human resources. Dissimilarities as well as similarities among twenty promising occupations were discovered according to the analysis result of the occupations in the environmental industry. A major discovery was that there are lots of difficulties in securing environment-related human resources. Primary reasons for the difficulties were inconsistent working conditions and the shortage of the qualified human resources. To solve the difficulties in securing the human resources, the curriculum of the educational and the training institutes should be innovated and the human resources from the institutes could be applied to the workplace directly after the graduation.

• Korean Institute of Interior Design Journal
• /
• v.19 no.6
• /
• pp.83-90
• /
• 2010

Emotional interest in the 1970s, Japan started from the technical and engineering beyond the scope, period late structuralist entering the world has been the subject of interest, as well as in academic research is becoming the main theory. In addition, communication between various disciplines such as humanities through the study of consilience and fusion, the human life to continue as a subject, its importance has risen. So this study are to design for the study of emotion through the human heart in space and how the expression of emotions and can be validated in a study. GSD to evaluate the action (verb) and emotional words (adjective) related to two variables to measure the degree of correlation coefficient was an experiment to find out. Picasso painting, it is 'difficult to understand', 'special', 'interesting', 'not interested', 'confused', 'fun', 'anxious', 'dark', 'cool', 'hard' to have relevance, such as the distribution of emotional words, and as a result of the move was a lot of work. This result can be obtained through the arcane resistance of the cubist paintings that make a lot of body movements. In Renoir painting 'stable', 'warm', 'soft', 'easy to understand', 'bright', 'boring', 'curious', such as emotional words ranged to have a relationship with this behavior is less motion in space. This result can be obtained through the understanding of the Impressionist paintings that are less body movements. As a result, space design, emotional design in the evaluation (GSD) for the empirical analysis that evaluated the feasibility and future of the emotional space of the design could be based in the area is considered.

• Fashion & Textile Research Journal
• /
• v.20 no.4
• /
• pp.474-481
• /
• 2018

For this study, we developed clothing in which textile materials that were excellent weather control function for the cold environment and we performed the human subject test with developed clothing to determine the thermal comfort. We used 2 clothing samples developed (A and B, hollow yarn+moisture absorption/quick drying yarn, 3 layers, high stretchable, heat reflection film and lamination treated) and a control sample (Ctrl.) for the human subject test and 8 adult males were used as a human subjects and environmental conditions of chamber were $0{\pm}1^{\circ}C$. $50{\pm}5%RH$, 0.3m/sec. The results were as follows: The average skin temperature and hand, thigh temperature of B were higher than B and Ctrl. (p<.05). The micro-climates of B were near to thermal comfort range which is $32{\pm}1^{\circ}C$ and $50{\pm}10%\;RH$. The chest temperature of B was significantly higher than others (p<.05). The relative humidity of B was lower than others and kept stable rather than others. The thermal sensation of B was near the "neutral" and was significantly different from Ctrl. (p<.01) and the weight loss of B was lower than Ctrl. (p<.05). The counting task and hand temperature was positively related and the counting task value of B and A is bigger than Ctrl. and that of A was bigger than Ctrl. (p<.05).

• Korean Journal of Human Ecology
• /
• v.23 no.4
• /
• pp.665-680
• /
• 2014

The purpose of this study was to develop the construction process of orthopedic compression garments (OCG) for balancing of the left and right lumbar muscle power and strength to prevent low back pain. One male subject having low back pain was involved for investigating of the lumbar muscle power. EMG (Telemyo DTS2, Noraxon, U.S.A) was measured with/ without 3 types of waist assistant belt around the waist area of the subject. Based on the electromyogram value of left and right body, OCG were constructed as follows. Firstly, stretchable t-shirts type with supportive waist belt was selected for the convenience of wearing and laundering the OCG. The design lines of the front and back waist parts were created depending on the anatomy of the torso. Secondly, 3D pattern was developed using 3D Clo, RapidForm XOR, 2C-AN, and Yuka CAD program to increase the fit of the OCG. Finally, stretchable power-net was layered as linings in two ways, a single lining and double layered linings, and evaluated measuring lumbar muscle EMG by five subjects with low back pain. As the results, they were effective to balance the left and right lumbar muscle power and strength. Also the OCG with the double layered power-net lining was superior to the one layered lining in terms of fit and comfort.