• Title/Summary/Keyword: Human materials

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Research Using Human Biological Materials and Institutional Review Board Review (인체유래물을 사용하는 연구와 Institutional Review Board 심의 )

  • Mi-Kyung Lee
    • The Journal of KAIRB
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    • v.6 no.2
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    • pp.33-37
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    • 2024
  • Recently, with the development of biotechnology and molecular genetics, research using human biological materials has been receiving attention, and the demand for the use of human- biological materials has also increased significantly. In particular, human biological materials contain the personal information of the person providing them, so special care must be taken to protect personal information throughout the entire process from drafting the human biological materials research plan, Institutional Review Board (IRB) review, and research progress. In addition, it is important to appropriately utilize residual human biological materials obtained during medical diagnosis and treatment at medical institutions to achieve scientific results, while protecting the rights of human biological materials providers and improving the method of expressing consent so as not to damage the trust of human biological materials providers in researchers. To this end, it is necessary to provide sufficient information and education so that researchers and IRB members can understand and apply related laws such as the Bioethics Act and the Personal Information Protection Act.

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A Study on the Formative Characteristics of how Transparent Materials Express a Human body (투명성 소재에 의한 인체 표현의 조형성 연구)

  • Lee, In Young
    • Fashion & Textile Research Journal
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    • v.20 no.1
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    • pp.1-9
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    • 2018
  • This study has its purpose in classifying the ways in which transparent materials appear in clothes creating a sample garment on this basis, and studying the formative characteristics of human body expression through materials. The study methods for this study are: first, related documents and precedent theses were researched. Second, the expression methods of transparent materials shown in the clothes collection were classified through objective research. Transparent refers to the lexical definition of being see-through, and the transparency of materials arises from the chemical components and physical characteristics of its raw materials. Transparent materials have been applied to clothes and expressed in diverse ways, revealing the beauty of the human body. Such expression methods of transparent materials are classified by the 'degree of transparency', 'presence of patterns', and 'range of use'. In clothes, transparent materials are depicted through 'revealing' which exposes the body, 'making seemingly lighter' which makes the body livelier, and 'overlapping' which overlaps the body with the structure and patterns of the material. Furthermore, transparent materials express the human body through having the beholder 'peep' into other parts of the body, 'imagine' areas which are covered by looking at the areas which are exposed, and through 'blurring' the boundaries or the shape of the human body, depending on the degree of transparency. As such, the study of the expression methods of transparent materials and human expression has its importance in that it explores the expression methods of materials and formative characteristics of human body expression through these methods.

Medicolegal Study on Human Biological Material as Property (인체 유래 물질의 재산권성에 대한 의료법학적 고찰)

  • Lee, Ung-Hee
    • The Korean Society of Law and Medicine
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    • v.10 no.2
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    • pp.455-492
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    • 2009
  • (Background) Recent biotechnological breakthroughs are shedding new lights on various ethical and legal issues about human biological material. Since Rudolph Virchow, a German pathologist, had founded the medical discipline of cellular pathology, issues centering around human biological materials began to draw attention. The issues involving human biological materials were revisited with more attention along with series concerns when the human genome map was finally completed. Recently, with researches on human genes and bioengineering reaping enormous commercial values in the form of material patent, such changes require a society to reassess the present and future status of human tissue within the legal system. This in turn gave rise to a heated debate over how to protect the rights of material donors: property rule vs. no property rule. (Debate and Cases) Property rule recognizes the donors' property rights on human biological materials. Thus, donors can claim real action if there were any bleach of informed consent or a donation contract. Donors can also claim damages to the responsible party when there is an infringement of property rights. Some even uphold the concept of material patents overtaking. From the viewpoint of no property rule, human biological materials are objects separated from donors. Thus, a recipient or a third party will be held liable if there were any infringement of donor's human rights. Human biological materials should not be commercially traded and a patent based on a human biological materials research does not belong to the donor of the tissues used during the course of research. In the US, two courts, Moore v. Regents of the University of California, and Greenberg v. Miami Children's Hospital Research Institute, Inc., have already decided that research participants retain no ownership of the biological specimens they contribute to medical research. Significantly, both Moore and Greenberg cases found that the researcher had parted with all ownership rights in the tissue samples when they donated them to the institutions, even though there was no provision in the informed consent forms stating either that the participants donated their tissue or waived their rights to ownership of the tissue. These rulings were led to huge controversy over property rights on human tissues. This research supports no property rule on the ground that it can protect the human dignity and prevent humans from objectification and commercialization. Human biological materials are already parted from human bodies and should be treated differently from the engineering and researches of those materials. Donors do not retain any ownership. (Suggestions) No property rule requires a legal breakthrough in the US in terms of donors' rights protection due to the absence of punitive damages provisions. The Donor rights issue on human biological material can be addressed through prospective legislation or tax policies, price control over patent products, and wider coverage of medical insurance. (Conclusions) Amid growing awareness over commercial values of human biological materials, no property rule should be adopted in order to protect human dignity but not without revamping legal provisions. The donors' rights issue in material patents requires prospective legislation based on current uncertainties. Also should be sought are solutions in the social context and all these discussions should be based on sound medical ethics of both medical staffs and researchers.

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Image of Transparency expressed in Dress (복식에 표현된 투명성의 이미지)

  • 박명희
    • Journal of the Korean Society of Costume
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    • v.50 no.2
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    • pp.111-123
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    • 2000
  • This study compares architecture with dress, investigates the image of transparency expressed in modern dress, and reveals its modern meaning. That is the purpose for this study. The study results are as follows. First, purity was expressed with simple, white color which has not any exaggeration or decoration, and transparent veils of wedding dress express clean and pure image which represents the original meaning of wedding dress. Second, eroticism conveys being erotic by exposing human body through transmission of light over transparent materials. Eroticism expressed by wearing thin and transparent dress with body-conscious line almost like being nude or emphasizing the sexually curious area in human body. The biggest difference in this study is that eroticism is delivered in dress, but not in architecture. Third, playfulness shows synchronism which recognizes human body with transmission of light over ,linear, transparent materials or recognizes inside dress. Playfulness expressed with location switch between inside and outside, exaggeration, distortion , and emphasis. Forth , openness makes dress atmosphere soft by putting transparent materials over opaque materials, expressed separation from restriction by wearing transparent dress over a naked human body, and expressed open ad free image by expressing human emancipation and freedom. Transparent dress expressed modern human being's sensitivity desire for living with light and joyful mood departing from heavy through, and also open and free image which pursues for freedom of human boedy departing from the restriction of human body.

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Standard based Deposit Guideline for Distribution of Human Biological Materials in Cancer Patients

  • Seo, Hwa Jeong;Kim, Hye Hyeon;Im, Jeong Soo;Kim, Ju Han
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.14
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    • pp.5545-5550
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    • 2014
  • Background: Human biological materials from cancer patients are linked directly with public health issues in medical science research as foundational resources so securing "human biological material" is truly important in bio-industry. However, because South Korea's national R and D project lacks a proper managing system for establishing a national standard for the outputs of certain processes, high-value added human biological material produced by the national R and D project could be lost or neglected. As a result, it is necessary to develop a managing process, which can be started by establishing operating guidelines to handle the output of human biological materials. Materials and Methods: The current law and regulations related to submitting research outcome resources was reviewed, and the process of data 'acquisition' and data 'distribution' from the point of view of big data and health 2.0 was examined in order to arrive at a method for switching paradigms to better utilize human biological materials. Results: For the deposit of biological research resources, the original process was modified and a standard process with relative forms was developed. With deposit forms, research information, researchers, and deposit type are submitted. The checklist's 26 items are provided for publishing. This is a checklist of items that should be addressed in deposit reports. Lastly, XML-based deposit procedure forms were designed and developed to collect data in a structured form, to help researchers distribute their data in an electronic way. Conclusions: Through guidelines included with the plan for profit sharing between depositor and user it is possible to manage the material effectively and safely, so high-quality human biological material can be supplied and utilized by researchers from universities, industry and institutes. Furthermore, this will improve national competitiveness by leading to development in the national bio-science industry.

Safe Industrial Manipulator Based on a Counterbalancing Mechanism with Adaptation to the Posture Change of a Robot Base Plane (로봇 설치면 자세 변화에 대응 가능한 자중 보상 기반 안전 매니퓰레이터)

  • Do, Hyun Min;Kim, Hwi-Su;Kim, Doo Hyeong;Choi, Tae-Yong;Park, Dong Il;Son, Youngsu
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.25 no.6
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    • pp.511-516
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    • 2016
  • Guaranteeing the safety of human workers around robots has become an important issue with the increasing demand for human-robot collaboration in industrial production lines. This study proposes a robot manipulator equipped with a counterbalancing mechanism that reduces the power of actuators required to drive the robot, thus keeping a human worker safer in a human-robot collaborative environment. A counterbalancing torque that exactly cancels out the gravitational torque in the proposed mechanism is generated by restoring the force of a spring in the counterbalancing mechanism. A prototype design and experimental results are presented to verify the effectiveness of the proposed method.

Biologic Response of Human Deciduous Dental Pulp Cells on Newly Developed MTA-like Materials (새로 개발된 MTA 유사 재료에 대한 유치 치수세포의 생물학적 반응)

  • Lee, Haewon;Shin, Yooseok;Jung, Jaeeun;Kim, Seongoh;Lee, Jaeho;Song, Jeseon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.42 no.4
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    • pp.291-301
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    • 2015
  • This study compared the in vitro cell viability and differentiation potentials of human deciduous dental pulp cells (DPCs) on mineral trioxide aggregate (MTA)-like products (ProRoot MTA, RetroMTA and Endocem Zr). The experimental materials were prepared as circular discs, which were used to test the effects of the materials on the viability of human DPCs when placed in direct and indirect contact. Furthermore, the pH of the extracted materials was recorded, and their effect on cell differentiation potential was evaluated by evaluating the alkaline phosphatase (ALP) activity and Alizarin Red S staining of DPCs incubated with the test materials. In direct contact, the cell viability of human DPCs was higher with ProRoot MTA and RetroMTA than with Endocem Zr. However, when in indirect contact, the cell viability of human DPCs was generally higher in Endocem Zr than in ProRoot MTA and Retro MTA. With respect to pH, the alkalinity was lower for Endocem Zr than for the other test materials. The ALP activities of the cells were not enhanced by any of the experimental materials. Alizarin Red S staining of the tested human DPCs revealed that their differentiation potential was lower than for cells incubated with osteogenic induction medium. While there were differences in the responses of the human DPCs to the test materials, all displayed degrees of cytotoxicity and were unable to enhance either the viability or differentiation of human DPCs. However, Endocem Zr exhibited better cell viability and was less alkaline than the other test materials.

Ignition Ability of Flammable Materials by Human Body's Electrostatic Discharge by Type of Fabric (옷감 종류별 인체대전 정전기 방전에 의한 인화성물질 점화능력)

  • Jong Soo Hyun
    • Journal of the Korean Society of Safety
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    • v.39 no.2
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    • pp.1-8
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    • 2024
  • Unwanted effects of electrostatic phenomena occur in various industries. Electrostatic problems originating from the human body in flammable atmospheres in the industry are especially concerning. A substantial volume of experimental data on the electrostatic charging voltages created on the human body owing to the rubbing of apparel were generated and reviewed during this study. The data were reviewed to determine whether the resultant charging levels of the human body are hazardous in flammable atmospheres. This study was conducted under several conditions, such as different fiber types used in apparel, shoe types, and relative humidities (RHs). The following conclusions were drawn in this study. ① The electrostatic charging levels of the human body owing to the rubbing of apparel increase with the increase in the surface resistances of apparel; however, the electrostatic charging levels may be different depending on the condition of the cloth surface. ② The discharging energy of 1.98-18.5 [mJ] from the human body exceeds the minimum ignition energy of most flammable materials, when removing an overcoat made of polyester, cotton and wool under severe conditions such as wearing height-raising shoes for men. ③ When removing antistatic apparel, the maximum discharging energy of 0.128 mJ from the human body is dangerous if the minimum ignition energy of the flammable material is between 10-5-10-4 [J] Grade; however, a minimum ignition energy of 10-3 J Grade of the flammable material is considered safe. ④ While wearing antistatic shoes, the electrostatic charging voltage generated in the human body when removing an overcoat is 30 V; therefore, wearing such shoes is a suitable countermeasure when handling flammable materials. However, the antistatic abilities of shoes reduce when thick socks are worn. ⑤ As RH increases, the electrostatic charging levels of the human body decrease. ⑥ The electrostatic charging levels of the human body from removing a cotton overcoat can ignite the majority of flammable materials when RH is less than 30% under severe conditions such as wearing height-raising shoes for men.

Moral Debate on the Use of Human Materials and Human Genome Information in Personalized Genomic Medicine: - A Study Focusing on the Right to be Forgotten and Duty to Share - (유전체맞춤의료를 둘러싼 인체유래물 및 인간유전체 정보의 도덕성 논쟁 - 잊혀질 권리와 공유할 의무를 중심으로 -)

  • JEONG, Chang Rok
    • The Korean Society of Law and Medicine
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    • v.17 no.1
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    • pp.45-105
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    • 2016
  • The purposes of this study is to debate the duty to share and right to be forgotten of human materials and human genome information in modern personalized medicine. This study debates the use of human materials and human genome information in modern personalized medicine from the perspectives of the duty to share and right to be forgotten. The arguments are based on personal and community aspects. In general, human genome information is considered the personal property of an individual. Nevertheless, on thinking carefully, we can understand that human materials and human genome information have both personal and community aspects. In this study, cases are examined including a HeLa cell, Guaymi woman cell strain, and Hagahai man cell, to support various debates an genetic information for database construction in personalized medicine. Finally, using moral theories, this study attempts to synthesize the dialectics of the duty to share and right to forget regarding the use of human materials and human genome information in medicine.

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Unfolding the Eigen Shin-Tou-Jil (Proper Body.Earth Materials) by the Algorithm of Human-ware (고유신토질(固有身土質)의 휴먼웨어적 전개)

  • 서윤정;유왕진
    • Journal of Korean Society for Quality Management
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    • v.28 no.1
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    • pp.13-26
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    • 2000
  • It is really hard for the material factors to basically improve quality of life, since it is the only partial means of the survival and activity of life. Development of Eigen Shin-Tou-Jil(Proper Body·Earth materials), therefore, must be concentrated on providing man with essential meaning of life, not with simply economic advantage. Eigen Shin-Tou-Jil(Proper Body·Earth materials) which is formed through long passage of time in the original environments that include the climate and nature features of a special region, the representative examples are like Korea Bong-sam(a kind of genseng) of Yellow Earth etc. Unfolding the Eigen Shin-Tou-Jil(Proper Body·Earth materials) by the Algorithm of Human-ware means the development for manifesting individual eigen motives and traits as subject of behavior(Gene-ware). It is because all plants, animals, inanimate objects, including Human, have evolved with their own values in the ecosystem. It was reported that a Baeksong(white pine tree), grown well up in TongEeDong, Seoul, Korea had rarely grown up during the period suppressed by Japan. By the developments of Bio-Engineering, we also found that 40% of gene base sequence of C. Elegance(a kind of worm) is identical to that of characteristic Human. In this reason, through considering common characteristics between Human and Nature, the developments of Eigen Shin-Tou-Jil(Proper Body·Earth materials) must begin with epoch for manifesting and understanding individual's Eigen motives and traits as subject of behavior(Gene-ware)

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