• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.4
• /
• pp.1891-1898
• /
• 2016

Imperata cylindrica, a tall tufted grass which has multiple pharmacological applications is one of the key ingredients in various traditional medicinal formula used in India. Previous reports have shown that I. cylindrica plant extract inhibited cell proliferation and induced apoptosis in various cancer cell lines. To our knowledge, no studies have been published on the effect of I. cylindrica leaf extract on human oral cancers. The present study was undertaken in order to evaluate the anticancer properties of the leaf extract of I. cylindrica using an oral squamous cell carcinoma cell line SCC-9 as an in vitro model system. A methanol extract from dried leaves of I. cylindrica (ICL) was prepared by standard procedures. Effects of the ICL extract on the morphology of SCC-9 cells was visualized by microscopy. Cytotoxicity was determined by MTT assay. Effects of the ICL extract on colony forming ability of SCC-9 cells was evaluated using clonogenic assay. Cell cycle analysis was performed by flow cytometry and induction of apoptosis was determined by DNA fragmentation assay. The ICL extract treatment caused cytotoxicity and induced cell death in vitro in SCC-9 cells in a dose-dependent manner. This treatment also significantly reduced the clonogenic potential and inhibited cell proliferation by arresting the cell cycle in the G2/M phase. Furthermore, DNA fragmentation assays showed that the observed cell death was caused by apoptosis. This is the first report showing the anticancer activity of the methanol extracts from the leaves of I. cylindrica in human oral cancer cell line. Our data indicates that ICL extract could be considered as one of the lead compounds for the formulation of anticancer therapeutic agents to treat/manage human oral cancers. The natural abundance of I. cylindrica and its wide geographic distribution could render it one of the primary resource materials for preparation of anticancer therapeutic agents.

• Journal of the Korea Society of Computer and Information
• /
• v.11 no.2 s.40
• /
• pp.93-99
• /
• 2006

Ontology is an indispensable component in intelligent and semantic processing of knowledge and information, such as in semantic web. Ontology is considered to be constructed generally on the basis of taxonomy of human concepts about the world. However. as human concepts are unstructured and obscure, ontology construction based on the taxonomy of human concepts cannot be realized systematically furthermore automatically. So, we try to do this from the relation among linguistic symbols regarded representing human concepts, in short, words. We show the similarity between taxonomy of human concepts and relation among words. And we propose a methodology to construct and generate automatically ontologies from these relations mon words and a series of algorithm to convert these relations into ontologies. This paper presents the process and concrete application of this methodology.

• Journal of the Daesoon Academy of Sciences
• /
• v.23
• /
• pp.109-152
• /
• 2014

This paper deals with the artistic expression of religious thought in terms of the uniqueness of different images and creativity. The relationship between religion and art is complicated but popular in modern society. Film becomes the icon of modern culture to enhance the knowledge of religious traditions. Among many Korean religious films, Kang Daejin's work, The Way of Peace (1984) contains the life and thought of Kang Jeungsan(1871-1909), the highest god of Daesoonjinrihoe. First, the film, The Way of Peace, pays attention to the legitimacy of succession from Kang Jeungsan to Cho Jeongsan(1895-1958). Korea was beset with trouble both at home and abroad. China, Japan, Russia, and the US had the colonial desire to conquer the lands of Korea and to explore natural resources. Though the people of Eastern Learning(東學) protested government and Japanese colonialists, Jeungsan applied the principle of non-violence to the world. In order to save all the living beings of the world, he reordered the universe and renewed the harmonic relationship of human beings and their spirit. Second, The Way of Peace proposed the soteriology of peace and change to audience regardless of seekers(道人) or not. Jeungsan transformed the closed society to the open society, changed divided religions to the transcendent truth(道). He empowered the marginalized people such as women, the lowly, the elderly, and the sick, who were oppressed in the Confucian society. And he redeemed the people from the disease by healing all diseases and correcting disorders. In conclusion, The Way of Peace is a good resource of religious education by which we can overcome the religious illiteracy. The knowledge of new religious movements and Daesoonjinrihoe is necessary for us to understand the diversity of human nature. In the near future, the new images of Jeungsan should be created through multi-media and cultural contents for the new generation.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.9 no.5
• /
• pp.141-155
• /
• 2014

This study examines the effect of previous work experience on the long-lived venture firm called 'Good Quality startup'. The research explores entrepreneurs of 16 mobile application startups that were invested by the venture capital, 'K-ventures', through the resource-based view. The results show that all of entrepreneurs had previous experiences of their business domain. They accumulated human resources such as technology capabilities, knowledge of domain, know-how, networking through learning-by-doing. Entrepreneur's human resources are the key factors for opportunity recognition and realisation process; and it is also on the ground that venture capital determines investment. Venture capital provides financial resources, management support and strong network for venture firm. Technology resources, financial resources, know-how and networking are the core managerial resources to be a long-lived venture firm called 'Good Quality Startup'. This research is an exploratory case study based on previous experience and 'good quality entrepreneurship'. The empirical study hereafter is needed.

• Journal of Practical Engineering Education
• /
• v.12 no.1
• /
• pp.49-60
• /
• 2020

With the advent of the knowledge-based era of the fourth industrial revolution, a paradigm shifts in university education. As a complete overhaul of university educational methods is required, strengthening competence through personalized is emerging as one of the solutions to the problem. To provide appropriate education accordingly focusing on individual learners, more studies at various levels are needed about understanding the characteristics of learners and ways to support them at universities. This study aims to conduct an exploratory research for adapting personalized learning at K University and explore effective ways to support. First, through literature review, the theoretical basis of personalized learning considering the diverse characteristics of learners and domestic and overseas cases of are examined. Secondly, a pilot study is conducted with K University students as subjects. FGI, study style diagnosis, one-on-one follow-up interviews are conducted and competency-based learning performance analysis and study style diagnosis result paper are provided to selected participants. Finally, major issues and implications are suggested to support the effective personalized learning of K university students.

• Journal of Korean Academy of Nursing Administration
• /
• v.8 no.1
• /
• pp.55-72
• /
• 2002

Purpose : This study aimed at understanding the lived experience of new graduate nurse in hospital setting.Method : This study was based on a phenomenological approach. For this study, 8 new graduate nurses participated. The unstructured in-depth interviews were carried out from June to October, 1998. The data was analyzed Van Kaam's method.Results : Clinical new graduate nurses experienced clinical adaptation and endeavor, professional conflict of nursing, disability of nursing performance, work stress and management, maladaptation of human relationships, diverse emotions of interpersonal relationships, change of personal identity, difference between theory and reality of nursing.Clinical adaptation and endeavor included to get familiar with hospital life, satisfaction and worth for nursing, to get familiar with scoldings, calm down by oneself, efforts for self-development. Professional conflicts of nursing included future uncertainties in the hospital, dissatisfactions in work, doubts and regrets in nursing.Disability of nursing performance included lack of knowledges and skills, desolate working, stresses from mistake in working. Work stress and management included psychological signs and symptoms, physical signs and symptoms, management of stress. Maladaptation of human relationships included unsuitabilities in nursing unit climate, difficulties in human relationship. Diverse emotions of interpersonal relationships included regrets and absurdities to clients, thanks and regrets to colleagues, difficulties with doctors, sense of rivalry with colleague nurses. Change of personal identity included to become narrowing life circle, change of personality. The differences between theoretical knowledge and practice included needs of systematic pre-education for clinical nursing practice, differences between nursing educations and clinical practices.Conclusion : Therefore, the human resource management reflecting new graduate nurses' experiences should be developed.

• Journal of the Korea Safety Management & Science
• /
• v.10 no.4
• /
• pp.297-307
• /
• 2008

At the spots of enterprises experiencing rapid environmental changes, necessity for ceaseless managemental innovation is raised. We can't deny that management quality is also a part of such managemental innovation. Introduction of management quality by an organization is different from introduction of other individual innovative techniques. Management quality is not one time project but complete historical change program to be pursued continuously. Furthermore, it must be understood as a strategic 'Quality Journey' looking for far future of an organization. Malcolm Baldrige Model has been increasingly used in Korea as a global standard for management quality. The model, however, has shown a number of limitations in application due to nonsystematic elements in the implementation process. The deployment process of the model should be detailed through a real world case study. In this research, we proposed a quality evaluation standard model which is suitable for the Korean public enterprise based on the Malcolm Baldrige Non-profit Criteria, and examined the model. A 7-Point Likert Scale was used based on the seven categories within the 2007 Malcolm Baldrige Non-profit Criteria: Leadership, Strategic Planning, Customer and Market Focus, Management Analysis and Knowledge Management, Workforce Focus, Process Management, and Results. Furthermore, we analysed the validity and causal relationship among the factors within the model. Through the above case study, following common factors for successful Malcolm Baldrige Model have been derived. The following is a summary of the results of this study. First, for Malcolm Baldrige Model management, needs powerful support Leadership. Second, for Malcolm Baldrige Model management, needs systematic Strategic Planning. Third, for Malcolm Baldrige Model management, needs the continuous Customer and Market Focus. Fourth, for Malcolm Baldrige Model management, needs systematic Measurement Analysis and Knowledge Management. Five, for Malcolm Baldrige Model management, needs systematic Workforce Focus. Six, for Malcolm Baldrige Model management, needs systematic Process Management. The finding are surely necessary factors to arrange the human resource management for upgraded management quality, those factors help to explain why all enterprises consider human resource as the strategic view.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.8 no.1
• /
• pp.137-147
• /
• 2013

The purpose of this study is to review the relationship between knowledge management and innovation, and the moderating effect of Convergence Federation in Small & Medium Business. In order to verify and achieve the purposes mentioned above, questionnaire data are gathered and analysed from 481 establishments located in Kangwon-do, Chungpuk-do, Kyunggi-do, Kyungpuk-do province and so on. Multiple regression and multiple hierarchical regression analysis are applied to test the proposed hypotheses: 1) the relationship between knowledge management and innovation, 2) the moderating effects of Convergence Federation's participation on the relationship between knowledge management and innovation. Empirical survey's findings are as follows; First, knowledge acquisition and application showed to be positively related with all innovation activities(organization innovation, human resource innovation, product innovation, and quality innovation). Second, Convergence Federation's participation strengthened the positive relationship between knowledge acquisition and product innovation, and it did also the positive relationship between knowledge application and product innovation.

• Journal of Korean Library and Information Science Society
• /
• v.37 no.2
• /
• pp.145-171
• /
• 2006

Motivated by the open access movement, research institutions are building Institutional repositories for a nation-wide knowledge distribution infrastructure. IKIS (Institute Knowledge Inventory System) was proposed to integrate materials produced by government-sponsored 23 institutions of the economic, social and human fields, to contribute for policy-making in national agenda and to proffer services to a people. As IKIS project goes on. the project turns out to be slower than planned especially In terms of building up content and improving system functions. This study aims to investigate the methods for promoting the system in terms of management and system developments using multiple research methods such as surveys and interviews. Five issues including budgets and marketing are proposed for the management strategies, whereas three ones Including content and system performance improvements are suggested for the system development. The study results can be utilized as guidelines for managing university and school repositories as well as IKIS.

• Journal of Information Management
• /
• v.42 no.4
• /
• pp.95-113
• /
• 2011

The new millennium with mystifying convergence of IT has opened new challenges to LIS profession. This has resulted to continuous skill development and lifelong learning, for capacity building in consonant with contemporary changes. The LIS profession in India has created several mechanisms to organize and conduct several skills development programmes through which professionals are continuously enabled to update their professional knowledge and skills, in practice and teaching. There is a good organizational infrastructure and identified areas related to the recent developmental trends and as such LIS professionals and educators have facilities for updating their knowledge at veritable levels and intervals. The paper has surveyed programmes conducted by different organizations at different levels and highlights the aspects of the organizational infrastructure and the emergent areas of applications in LIS teaching, research and professional practices in India. The selection of areas and subjects for various skill development programmes suggest the competencies acquired by the LIS professionals from India, and the empowerment of their professional knowledge can be of immense value to its neighbouring countries. The paper highlights the knowledge and competencies of the LIS professionals in India and the broad-based facilities available here which can be a model for those countries which are seeking to utilize the LIS human resources from this part of the sub-continent. The paper in this circumstance surveyed on the institutional infrastructure for skill developmental opportunities available in India which would meet such requirements within and to the countries outside in the South Asian region seeking its collaboration in such manpower development work.