• Archives of design research
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• v.12 no.4
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• pp.89-98
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• 1999

The application of tool which has grown rapidly by the age was used for the product development, however as today the computer digitalization has been fixed to the necessary process in every factory-made mass production, making the sensitive desire of designer the digitalization through systematic, rational information database building from the planning level of product to the final mass production in such a environment change. It should satisfy a variety of needs of consumer. The enterprise that hopes to get a winner in the present age brought in computer with useful tool to process information efficiently. The computer has displayed much more excellent computation ability than human to come up to their expectation and the growth of electronic technology was possible to make the computer's high-efficiency, economy and integration. No matter what we have a good economy and integration. No matter what we have a good information there is no meaning unless we are able to use it' so we should take it out by the our need. Therefore, this paper observes a future-oriented possibility of computer & Telecommunication in information society, information-oriented design environment and the trends of minimal and integrated computer. We will improve the designer's ability to develop a novel product that have the diversification of them using application, aiming at computer utilization and image identification design strategy of product in the age of network telecommunication.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.6
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• pp.1137-1146
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• 2006

Under this economic circumstance, the logistics firms located in port take better advantages than those in other areas. This study observed those firms with consciousness to which matters were affected a growth of the logistics IT firms. This study considered in terms of three factors which are an economic factor, a political factor and an internal-ability factor for the matters of logistics IT firms' success through the factor analysis. According to the factor analysis, subjective factor showed positive: (1) expanding market through the ideas and abilities, (2) internal relations and government support (3) capability of market identification and focusing on regional industrialization. As a result of the internal ability analysis, there were three positive matters such as (1) a factor of organization or human resource management, (2) relationship with consumer and resource and management ability for strategy, and (3) developing unique product, networking, suitable goods of regional industrialization. The external factor, through the factor analysis was trued out (1) a emerged political factor such as a support up venture, cluster composition, investing R&D and specialist training, (2) economic factor such as tax reduction, financial support, marketing collaboration renting office in a low price by regional government.

• Korean Journal of Microbiology
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• v.47 no.4
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• pp.295-301
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• 2011

Aquaporin is a water channel protein, which is classified as Major Intrinsic Protein (MIP), found in almost all organisms from bacteria to human. To date, more than 200 members of this family were identified. There are two major categories of MIP channels, orthodox aquaporins and aquaglyceroporins, which facilitate the diffusion across biological membranes of water or glycerol and other uncharged compounds, respectively. The full genome sequencing of various fungal species revealed 3 to 5 aquaporins in their genome. Although some functions of aquaporins found in yeast were characterized, however, no functional characteristics were studied so far in filamentous fungi, including Aspergillus sp. In this study, one orthodox aquaporin homolog gene, aqpA, and four aquaglyceroporin homologs, aqpB-E, in a model filamentous fungus Aspergillus nidulans were identified and the function of the aqpA gene was characterized. Knock-out of the aqpA gene didn't show any obvious phenotypic change under the osmotic stress, indicating that the function of the gene does not involved in the osmotic stress response or the function could be redundant. However, the mutant showed antifungal susceptibility resistance phenotype, suggesting that the function of the aqpA gene could be involved in sensing the antifungal substances rather than the osmotic stress response.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.28 no.1
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• pp.1-17
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• 2018

Objectives: This research is part of a study to be conducted over five years starting from 2017 by the Ministry of Environment on the development of technologies to evaluate the impact of chemical accidents on the human body. Methods: For this research, a five-stage specific study method was developed. Results: In brief, the developed health risk assessment method can be summarized as follows. First, a health risk assessment system was built based on the guidelines set forth by the USA NRC/NAS. Second, based on the disease manifestation theory, the health risk assessment method was divided into 1) a carcinogenic health risk assessment method focused on all carcinogens except non-genotoxic carcinogens and 2) a non-carcinogenic health risk assessment method focused on noncarcinogens including non-genotoxic carcinogens. Third, the detailed contents of the health risk assessment method were developed in four stages(hazard identification, dose-response assessment, exposure assessment, and risk determination) through theoretical consideration of the assessment of the level of health risk related to chemical exposure. Finally, a health risk assessment methodology, classified into stages to address acute, subacute/subchronic, and chronic conditions was developed after considering the physicochemical behavior of hazardous chemicals upon implementation of countermeasures after a chemical accident. Conclusions: A method to evaluate the health risks related to toxic chemicals generated by chemical accidents was developed. This study was performed with the purpose of developing a mathematical health risk assessment method to evaluate the health effects of exposure to hazardous chemicals upon implementation of emergency countermeasures after chemical accidents.

• Parasites, Hosts and Diseases
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• v.29 no.4
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• pp.315-324
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• 1991

Each of SPF chicken(Hi-Line strain, 2-day-old males) was inoculated with 2.5 or $5\times10^4$ oocysts by stomach tube. The oocyst was the medium type of Cryptosporidium previously isolated from Korean chicken origin, and passed in 2-day-old SPF chicken. The patterns of oocyst discharge were monitored daily, and in order to observe the ultrastructure of the developmental stages, the bursa of Fabricius of the chicken was examined by transmission electron microscopy (TEM) on the 12th day postinoculation. The prepatent period for 8 chicken was 5.9 days postinoculation on the average, and the patent period was 12.9 days. The number of oocysts discharged per day for the chicken was reached peak on day 12 postinoculation on the average. A large number of oocysts was found in fecal samples obtained from inoculated chicken on days 8~14 postinoculation. The ultrastructural feature of almost every developmental stage of the medium type from chicken was very similar to that of Cryptosporidium previously isolated from mammalia including human and birds except for the attachment site of C. tsuris to the mucus cell from mammalia, but dimension of the oocysts from fecal samples of the medium type was different from those of C. meleagridis and mammalia origin. The above results reveal that the medium type of Cryptosporidium of Korean chicken origin is identified as Cryptosporidium baileyi.

• Journal of Life Science
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• v.18 no.4
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• pp.447-453
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• 2008

Zinc is an essential trace element in Human Being. Highly zinc containing yeast strain isolated from the tropical fruit, rambutan and the zinc concentration in this yeast strain was 306 ppm (30.6 mg%)per dry matter basis. This strain was found to be a rounded type, normal size, and multi-polar budding. Phylogenetic analysis using the ITS1-5.85 rDNA sequences from isolated strain is most similar to yeast Saccharomyces cerevisiae at the level of nucleotide sequence identity at 99%. This strain was produced alcohol by about 12% using fully colonized koji-rice with Aspergillus oryzae. In conclusion, the isolated strain was found to be closely related to the S. cerevisiae based on its morphological and physiological properties, and alcohol fermentation. The phylogenetic analysis of strain FF-10 using ITS 5.8S rDNA sequence data also supported the closely related to the S. cerevisiae. Accordingly, the isolated yeast was named as S. cerevisiae FF-10. Further studies on the best culture conditions for zinc production from zinc-enriched S. cerevisiae FF-10 are under investigation.

• Mass Spectrometry Letters
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• v.8 no.2
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• pp.39-43
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• 2017

Meldonium is a drug for treating ischemia by expanding the arteries but it can also enhance the performance of sports players. The World Anti-Doping Agency (WADA) has included it in the list of prohibited substances since 2016. Meldonium is one of the challenging substances for anti-doping testing because it is difficult to recover by general liquid-liquid or solid phase extraction due to its permanent charge and high polarity. Therefore, high-performance liquid chromatography (HPLC) is currently used by injecting a diluted urine sample (known as the "dilute-and-shoot" strategy). There is no loss of target compounds in the extraction/cleanup procedure but its high matrix effect could interfere in their separation or detection from the endogenous urinary compounds. We report a single method using high-resolution mass spectrometry that can be used for both screening and confirmation, which follows the "dilute-and-shoot" strategy. In this method, the endogenous compounds' interfering peaks in the mass spectrum are separated at a high resolution of FWHM 140,000, and the results are suitable for substance detection following the WADA guidelines. The interferences in the obtained mass spectrum of the urine matrix are identified as acetylcholine, lysine, and glutamine by further analysis and database searching. Validation of the method is performed in routine anti-doping testing, and the limit of detection is 50 ng/mL. This method uses simple sample preparation and a general reverse phase HPLC column, and it can be easily applied to other substances.

• Journal of Gifted/Talented Education
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• v.14 no.3
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• pp.41-52
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• 2004

No educational provision for the gifted and talented works in a cultural vacuum, and this is as true for out-of-school activities as for what happens in school itself. There is evidence that excellence in children's achievements can come from widely differing special provision or from no special provision at all. Cultural influences affect attitudes as to who might be gifted and talented and what might be done for them. Whatever the size and influence of special centres anywhere, there is always overlap between in-school and out-of-school activities. For all styles of provision, cooperation between the two is a vital aspect of success. The major cultural dichotomy in this field is between the perception, usually found in the Far East that 'most children have gifted potential' and the largely Western view that 'few children have gifted potential'. It is safe to say that children who are selected for aptitude and ability, and who are keen to learn, will get more from special enrichment than those who of equal potential who have not had that experience. But this does not necessarily show the provision as the best possible method for enhancing gifts and talents. In fact, I do not know of a single scientific investigation, either cross-culturally or within one country, which compares any aspect of an out-of-school programme with another. As a result it is hard to say what type of provision would be most appropriate and effective in any given situation. Outcomes are also dependent on the enthusiasm, organisation and money put into any scheme - as well as the way youngsters are chosen for it. Some of the largest and most influential out-of-school American institutions were founded on the psychological understanding of human abilities that was current in the 1920s. These early influences of seeking an IQ cut-off point (or equivalent) to identify the gifted still affect their practice. in addition, the big American Talent Searches so often select youngsters for summer-schools not only by their high-level achievements, but also by their parent's ability to pay the sometimes high fees. Opinions about the identification of the brightest children and consequential educational practice underlie all provision for their education, whether in or outside school hours. Because of cross-cultural differences, it would not seem wise to copy any action directly from one culture to another without recognising these influences and possibly modifying the model. The growing trend around the world is to offer high-level opportunities to as many youngsters as possible, so that no keen learner is turned away without even a change of sampling them.

• Journal of Korean Classical Literature and Education
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• no.34
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• pp.5-39
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• 2017

The purpose of this study is to establish genre knowledge that can be used to study classical Korean novels. Genre knowledge is important because it characterizes individual works based on their knowledge, as well as organically links them with the social context. In this study, I suggest that long classical Korean novels with similar contents can be analyzed using genre knowledge and analyze the "register" of the representative work Sohyeonsungrok as an example of a classical Korean novel. In the Sydney school, register connects genre and language. Register comprises field, tenor, and mode in the social context, and ideological meaning, interpersonal meaning, and textual meaning through language. These three meanings help us to understand how experiences are transformed into language, the relationship between participants, and the way a text is organized. Based on these frameworks, this study reveals that the linguistic features of Sohyeonsungrok is "an attitude that accepts a wide range of human emotions and desires and steadily waits for it to be included in norms." Classic Korean novels such as Sohyeonsungrok depict characters who are not wicked even though they cannot fully comply with social norms, and thereby create sympathy for family members living through Confucian ideology. This genre knowledge is useful for understanding the ideological implications of classical Korean novels.

• Journal of Korean Philosophical Society
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• v.129
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• pp.341-366
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• 2014

This Thesis analyzes the two forms of Confucian Golden Rule(Shu恕) that were proposed by Zhu Xi朱熹 and Dai Zhen戴震 each other, and researches their ethical significances. Zhu Xi don't regards Shu as universal ethics by itself, while Dai Zhen identify Shu as the ground of universal ethics, According to this thesis, Zhu Xi thought that Shu has a danger of immoral misusage in some situation because Shu is so simplistic form of identification. Because this, Zhu Xi, for the purpose of blocking arbitrary misusage of Shu and holding universality of ethics, suggests that moral sincerity(Zhong忠) of subject is necessary to practice of Shu. Dai Zhen, however, criticizes Zhu Xi's Ethical Structure. In Dai Zhen's view, Zhu xi's idea that the subject has to establish his own morality through Zhong before practice Shu cannot make him escape from subjectivity necessarily. In this point, Dai Zhen revive Shu. His Shu concept means the reciprocity of human desires to each other. But Dai Zhen's idea, as Zhu Xi worried, has a danger of immoral misusage in some situation. On this problem, this thesis elucidates that Dai Zhen' desire concept is not individual various desires but is common basic desires of existence, thereby attests that Dai Zhen's Shu is safe from immoral misusage. This thesis claim that even if Zhu Xi's and Dai Zhen's position is so different, the ethical aims of two scholars is same. They both attempted to overcome the evil of subjectivism and to procure universality of ethics, furthermore to accomplish social fairness. Consequently, this thesis claims that two scholars both walked in same way because both wanted to establish the universality of Shu and to pursue realization of social fairness.