• Title/Summary/Keyword: Human effects

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Physicochemical of Turnip Baek-Kimchi and Anti-Cancer Effects of Human Gastric Cancer Cells (AGS) (순무백김치의 이화학적 특성 및 인체위암세포(AGS)의 항암효과)

  • Im, Gum Ja;Kang, Soon Ah
    • The Korean Journal of Food And Nutrition
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    • v.35 no.2
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    • pp.127-136
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    • 2022
  • Comparing the quality characteristics of kimchi were measured and anticancer effects using AGS human gastric cancer cells were observed. Five kinds of kimchi samples were made of Kanghwa Baek kimchi (KB), Kangwha Turnip kimchi (KT), Turnip: Chinese cabbage = 1:1 Baek kimchi (T1B1), Turnip:Chinese cabbage = 4:1 Baek kimchi (T4B1), Turnip mul kimchi (T). As a result T kimchi showed the best fermentation characteristics among the five samples. T kimchi had a lower percentage of the total number of aerobic bacteria, while the number of lactobacillus was higher than that of other samples. The mRNA and protein expression levels of apoptosis-related factors found that T kimchi significantly increases the mRNA expression levels of caspases-3 and caspases-9 in AGS human gastric cancer cells as compared to the other kimchi samples. It showed high anticancer effects in the order of T, T1B1, and KB kimchi. As the anticancer effect of Turnip mul kimchi made only of turnip was higher, the higher the turnip content, the higher the anticancer effect. These results show that there were changes in fermentation characteristics such as pH, acidity, number of lactic acid bacteria, and anticancer effects according to the ratio of turnip and cabbage.

Isomorphism, Human Resource Capability and Its Role in Performance Measurement and Accountability

  • WULANINGRUM, Puspita Dewi;AKBAR, Rusdi;SARI, Martdian Ratna
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.12
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    • pp.1099-1110
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    • 2020
  • This research tests the effects of institutional pressures, the use of performance measurement systems and accountability, and moderation effects of human resource capability between institutional pressures and the use of performance measurement systems in the Local Government institutions in Indonesia. The research aims to provide empirical evidence both quantitatively and qualitatively that isomorphism institutional pressures occurred in the scope of implementation of the performance measurement system and accountability in the public sector organizations and to show the importance of human resource capability enhancement in reducing external pressure impact. In addition, it tries to develop the correlation model of institutional pressures, human resource capability, implementation of the performance measurement system, and accountability of public sector organizations. The research used mixed methods with sequential explanatory design. The data collection used surveys and interviews in 209 regency/Special Region of Yogyakarta and Central Java local governments as samples. The research result indicated that the institutionalization process of the performance measurement is influenced by institutional pressures, especially coercive and mimetic pressures. Human resource capability was unable to weaken institutional pressures effects in the performance measurement system implementation. The research also proved that the use of a performance measurement system was able to improve local government institution accountability.

Combined Effects of Cell Cultured Acanthopanax Senticosus Supplementation and Exercise on Lipid Profiles, Carnitine and Leptin Levels in Mice

  • Koo, Bon-Sun;Soh, Ju-Ryoun;Cha, Youn-Soo
    • Nutritional Sciences
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    • v.9 no.4
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    • pp.273-279
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    • 2006
  • The purpose of this study was to determine the independent and the combined effects of cell cultured Acanthopanax senticosus extracts (ASE) supplementation and swimming exercise on body weight, lipid profile, carnitine and leptin levels in C57 BL/6J mice. Forty C57BL/6J mice were divided into four groups: non-supplement and non-exercise (NSNE); non-supplement and exercise (NSE); supplement and non-exercise (SNE); supplement and exercise (SE) mice. They were allowed free access to food and water. The exercised groups were forced to swim (1hr, 6 days a week) in a water bath for 12 weeks. The supplemented groups were fed Cell cultured ASE (0.5 g/kg body weight/day) for 12 weeks. In this study, we found that the combination of Cell cultured ASE supplementation and exercise significantly decreased liver triglyceride (TG) level and serum leptin level but significantly increased serum HDL-cholesterol level compare to control (NSNE) group. These improved lipid profiles and decreased serum leptin would have positive effects on obesity and cardiovascular disease.

Effect of Apoptosis Induction of Ailanthus altissima on Human Lung Carcinoma Cells

  • Hwang, Yu-Jin;Woo, Hye-Im;Kim, Inhye;Park, Dong-Sik;Kim, Jaehyun;Om, Ae-Son;Hwang, Kyung-A
    • Journal of agriculture & life science
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    • v.45 no.5
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    • pp.91-96
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    • 2011
  • We investigated the inhibitory effects of solvent extracts from Ailanthus altissima in A549 human lung cancer cell. A. altissima has been recognized as a traditional healthy food due to its various biological activities against hypertension, strokes, fever, pain, neuralgia, inflammation, and cancer effects. Recently, it has been reported that the extracts of various wild vegetables show strong anti-cancer properties by induction of apoptosis. However, the mechanisms of their cytotoxicity in human lung cancer cells have been poorly understood. The present study was investigated the effects of solvent extracts from A. altissima on cell growth and apoptosis on A549 human lung cancer cells. A treatment of A. altissima inhibited the growth of A549 cells in a dose-dependent manner by inducing apoptosis. Especially, the chloroform fraction showed the highest anti-cancer effect among five kinds of fractions. And also, induction of apoptosis by chloroform fraction were associated with down-regulation of Bcl-2, and up-regulation of pro-apoptotic Bax expression. From these results, A. altissima may have a therapeutic potential in human lung cancer cells and as a functional food.

Effects of whole-body vibration on human performance (전신진동이 인간성능에 미치는 영향)

  • 이남식;박세진;김철중
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1990.10a
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    • pp.91-98
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    • 1990
  • This paper reviews the previous researches related to the effects of whole-body vibration on human performance. The physiological effects of vibration were reviewed in the first part, and the effects of vibration on vision and manual control performance were discussed. the relationships between vibration and ride quality were also discussed. ISO-2631 was briefly reviewed, and cautions and limitations were discussed to avoid misinterpretations when we accomodate Korean population to this standard. Further researches were recommended to get better understanding of response characteristics of Korean to whole-body vibration.

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Analysis of the effects of human head and hand on the radiation chracteristics of hand-held transceiver (인체의 머리와 손이 개인휴대 단말기의 복사특성에 미치는 영향 해석)

  • 윤종철;최재훈
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.35D no.7
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    • pp.1-8
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    • 1998
  • In this paper, the radiation characteristics of a bar-type tranceiver are analyzed by using FDTD method and the effectiveness of the analysis method is verified by comparing the calculated data with experimental data. The effects of human head and hand on the radiation characteristics of fold-type transceiver are analyzed. In order to observe the effects of human head and hand on the input impedance and far-field radiation pattern, a fold-type transceiver with .lambda./4 monopole antenna wrapped by human hand operating in the proximity of hea dis modeled an analyzed.

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The Effects of Human Rights Education Activities using Bullying Fairy Tales on Young Children's Human Rights-Related Attitudes and Self-Esteem (부링(Bullying)동화를 활용한 인권교육 활동이 유아의 인권관련태도 및 자아존중감에 미치는 영향)

  • Na, Jung Sook;Kim, Kyung Sook;Kim, Hee Young
    • Korean Journal of Childcare and Education
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    • v.12 no.2
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    • pp.89-112
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    • 2016
  • The present study examined effects of human rights education activities using bullying fairy tales on young children's human rights attitudes and self-esteem. The subjects of the study were a total of 40 five years old. children. Twenty of children were assigned to an experimental group and the other 20 children were assigned to a control group. The experimental group participated in human rights education activities using bullying fairy tales 21 times, 3 times a week for 7 weeks and the control group participated in Nurui curriculum activities during the same periods.. The study results indicated that the experimental group showed more improvement in their human rights attitudes and self-esteem than the control group. Therefore human rights education activities using the bullying fairy tales used in this study might be an effective educational mothod to enhence young children's human rights attitudes and self-esteem.

The Effect of Internationalized Human Capital on Export Performance of SMEs: Focusing on the Moderating Effects of Export Experience and Export Market Diversification (국제화된 인적자본이 중소기업의 수출성과에 미치는 영향: 수출경험과 수출시장다변화의 조절효과를 중심으로)

  • Young-Soo Yang;Jae-Eun Lee
    • Korea Trade Review
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    • v.46 no.3
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    • pp.171-184
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    • 2021
  • The purpose of this study is to analyze the effect of internationalized human capital on SME's export performance and to examine the moderating effects of export experience and export market diversification of SMEs that can affect the relationship between internationalized human capital and export performance of SMEs. The results of empirical analysis of 150 small and medium-sized enterprises located in Jeonnam province are as follows. First, the internationalized human capital of SMEs was found to have a positive (+) effect on export performance. Second, as a result of empirically analyzing the moderating effect of internationalized human capital on export performance, the export experience of SMEs was found to have a negative (-) moderating effect on the relationship between internationalized human capital and export performance of SMEs, and the export market diversification had a negative (-) moderating effect on the relationship between internationalized human capital and export performance of SMEs. This study provides meaningful theoretical implications in that this study identified the role of human capital by analyzing the relationship between internationalized human capital as an important source of competitive advantage of SMEs and export performance.

Genistein Combined with Exercise Improves Lipid Profiles and Leptin Levels in C57BL/6J Mice Fed a High Fat Diet

  • Seong, So-Hui;Ahn, Eun-Mi;Sohn, Hee-Sook;Baik, Sang-Ho;Park, Hyun-Woo;Lee, Sang-Jun;Cha, Youn-Soo
    • Food Science and Biotechnology
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    • v.16 no.6
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    • pp.910-917
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    • 2007
  • The aim of this study is to determine the anti-obesity effects of genistein and exercise, separately and in combination, in mice. Fifty male C57BL/6J mice were divided into 5 treatment groups: normal diet (ND), high fat diet (HD), high fat diet with exercise (HD+Ex), high fat diet with 0.2% genistein (HD+G), high fat diet with 0.2% genistein, and exercise (HD+G+Ex). They were allowed free access to feed and water, and exercised mice engaged in swimming on a regular basis for 12 weeks. Genistein supplemented mice gained less weight, had lower energy intake, better lipid profiles, and lower leptin than the HD mice. Furthermore, when genistein was combined with exercise (HD+G+Ex) the effects were even greater. HD, HD+Ex, and HD+G mice exhibited increased hepatic CPT-1 mRNA expression. Therefore, genistein and exercise has anti-obesity effects, as shown by changes in body weight, fat accumulation, energy intake, and leptin levels.

The Effects of Whitening Compoments on Human Melanocytes on virto

  • Cho, Joon-Hwan;Lee, Ki-Moo;Kim, Nam-Soo;Kang, Won-Hyoung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.23 no.3
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    • pp.115-121
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    • 1997
  • To identify inhibitors of melanogenesis, we compared the effects of 5 compounds on mushroom tyrosinase, human melanocytic tyrosinase activity and melanin content. The cytotoxicyty of the components were also tested on cultured human melanoctes. Kojic acid showed marked inhibitory effect both on mushroom and human tyrosinase activity. This action of kijic acid is stronger than that of ascorbic acid. Arbutin inhibited human tyrosinase activity of cultured melanocytes although it had slightly inhibitory effect on mushroom tyrosinase activity. Azelaic acid had no effect on human tyrosinase activity. Melanin production was inhibited significantly by kojic acid and tranexamic acid. MTT assay showed that all of the compounds were non-cytotoxic to melanocytes at the concentrations tested. These results suggest that the effect of kojic acid on cultured meanocytes involve inhibition of tyrosinase activity and melanogenesis without affection the cell number.

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