• Title/Summary/Keyword: Human anatomy

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Intramuscular neural distribution of the teres minor muscle using Sihler's stain: application to botulinum neurotoxin injection

  • Kyu-Ho Yi;Soo-Bin Kim;Kangwoo Lee;Hyewon Hu;Ji-Hyun Lee;Hyung-Jin Lee
    • Anatomy and Cell Biology
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    • v.56 no.3
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    • pp.322-327
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    • 2023
  • The aim of this study was to elucidate the intramuscular arborization of the teres minor muslce for effective botulinum neurotoxin injection. Twelve specimens from 6 adult Korean cadavers (3 males and 3 females, age ranging from 66 to 78 years) were used in the study. The reference line between the 2/3 point of the axillary border of the scapula (0/5), where the muscle originates ant the insertion point of the greater tubercle of the humerus (5/5). The most intramuscular neural distribution was located on 1/5-3/5 of the muscle. The tendinous portion was observed in the 3/5-5/5. The result suggests the botulinum neurotoxin should be delivered in the 1/5-3/5 area of the teres minor muscle.

The Present Situation and Problems of Human Anatomy in Oriental Medicine (한의학에서 사람해부학 교육의 현황과 문제점)

  • Kim, Soo-Myung
    • Journal of Haehwa Medicine
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    • v.5 no.2
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    • pp.445-448
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    • 1997
  • The human anatomy is the fundamental subject which is required lots of time and efforts for medical students. But most of the oriental medical students think it little important field. And moreover they have no active attitudes in their courses. In order to improve the present situation, the results obtained from this study are as follows: 1. As a Law of Cadaver Conservation revised systemically, there's need to have enough cadavers for dissection. 2. The teaching method must be converted into the laboratory technique with the strengthening human anatomy. 3. With opening a neuroanatomy course in oriental medical curriculum, the quality of nervous system is expected to increase. 4. Under the current medical system, there's need to have discussion deeply about the histology course.

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Histomorphological changes in the common carotid artery of the male rat in induced hypogonadism

  • Cheruiyot, Isaac;Olabu, Beda;Kamau, Martin;Ongeti, Kevin;Mandela, Pamela
    • Anatomy and Cell Biology
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    • v.51 no.4
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    • pp.284-291
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    • 2018
  • The role of androgens in the development of cardiovascular diseases remains controversial. The current study therefore sought to determine the changes in the histomorphology of the common carotid artery of the male rat in orchidectomy-induced hypogonadism. Twenty-two Rattus norvegicus male rats aged 2 months were used. The rats were randomly assigned into baseline (n=4), experimental (n=9), and control (n=9) groups. Hypogonadism was surgically induced in the experimental group by bilateral orchiectomy under local anesthesia. At experiment weeks 3, 6, and 9, three rats from each group (experimental and control) were euthanized, their common carotid artery harvested, and routine processing was done for paraffin embedding, sectioning, and staining. The photomicrographs were taken using a digital photomicroscope for morphometric analysis. Orchidectomy resulted in the development of vascular fibrosis, with a significant increase in collagen fiber density and decrease in smooth muscle and elastic fiber density. Moreover, there was development of intimal hyperplasia, with fragmentation of medial elastic lamellae in the common carotid artery of the castrated rats. Orchidectomy induces adverse changes in structure of the common carotid artery of the male rat. These changes may impair vascular function, therefore constituting a possible structural basis for the higher incidences of cardiovascular diseases observed in hypogonadism.

Botulinum neurotoxin injection for treating plunged nose and post-rhinoplasty: anatomical perspectives of depressor septi nasi, nasalis, leveator labii superioris alaeque nasi muscle

  • Kyu-Ho Yi;Ji-Hyun Lee;Seon-Oh Kim;Hyewon Hu;Hyung-Jin Lee;You-Jin Choi;Tae-Hwan Ahn;Hee-Jin Kim
    • Anatomy and Cell Biology
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    • v.56 no.4
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    • pp.409-414
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    • 2023
  • Botulinum neurotoxin (BoNT) injection for the treating plunged nose, post-rhinopasty and hyaluronic filler migration is common procedures in clinical settings. However, the lack of thorough anatomical understanding makes it difficult to locate the nose region muscles. The anatomical considerations concerned with BoNT injection into the nasalis, levator labii superioris alaeque, and depressor septi nasi muscles were reviewed in this study. The injection spots have been presented for the nasalis, levator labii superioris alaeque, and depressor septi nasi muscles, with the recommended injection technique for each muscle. We have suggested the ideal injection sites in association with outer anatomical landmarks of the nose region. Moreover, these proposals would support a more accurate procedure of BoNT injection in relieving plunged nose, preventing post-rhinoplasty deviation, and migration of the hyaluronic acid filler.

Development of Anatomy Education Software System (해부학 학습을 위한 소프트웨어의 개발)

  • Kim, Chang-Il
    • Proceedings of the KOSOMBE Conference
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    • v.1993 no.11
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    • pp.187-189
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    • 1993
  • I developed a computer program that can be used in studying the human anatomy. The program not only displays anatomical images, but also it gives some questions about the name of organs in the human body and evaluates tile answers. The program helps students scrutinize the detailed human anatomy by providing a way of interactive zooming anatomical images. To make the program more useful, better anatomical images need to be collected, and a context-sensitive search-and-view facility should be equipped with.

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Effects of Adenoviral Gene Transduction on the Stemness of Human Bone Marrow Mesenchymal Stem Cells

  • Marasini, Subash;Chang, Da-Young;Jung, Jin-Hwa;Lee, Su-Jung;Cha, Hye Lim;Suh-Kim, Haeyoung;Kim, Sung-Soo
    • Molecules and Cells
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    • v.40 no.8
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    • pp.598-605
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    • 2017
  • Human mesenchymal stem cells (MSCs) are currently being evaluated as a cell-based therapy for tissue injury and degenerative diseases. Recently, several methods have been suggested to further enhance the therapeutic functions of MSCs, including genetic modifications with tissue- and/or diseasespecific genes. The objective of this study was to examine the efficiency and stability of transduction using an adenoviral vector in human MSCs. Additionally, we aimed to assess the effects of transduction on the proliferation and multipotency of MSCs. The results indicate that MSCs can be transduced by adenoviruses in vitro, but high viral titers are necessary to achieve high efficiency. In addition, transduction at a higher multiplicity of infection (MOI) was associated with attenuated proliferation and senescence-like morphology. Furthermore, transduced MSCs showed a diminished capacity for adipogenic differentiation while retaining their potential to differentiate into osteocytes and chondrocytes. This work could contribute significantly to clinical trials of MSCs modified with therapeutic genes.

The first report of the buckled thyroid cartilage in a human cadaver

  • Craig Ballard;Joe Iwanaga;Eva Maranillo;Jose Sanudo;Aaron S. Dumont;R. Shane Tubbs
    • Anatomy and Cell Biology
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    • v.56 no.2
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    • pp.268-270
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    • 2023
  • We present the first case of buckled thyroid cartilage identified in a human cadaver. This rare anatomical variant, in patients, often produces dysphonia and is a potential source for diagnostic confusion. In the cadaveric case described, the laryngeal prominence is deviated to the left without deviation of the internal structures of the larynx, such as vocal folds and vocalis muscles. The medical history of the patient is not known. Finally, a review of current literature on the buckled thyroid cartilage is presented. Such a case represents a rare opportunity to visualize this deformity via anatomical dissection.

Anatomic Description of the Infraorbital Soft Tissues by Three-dimensional Scanning System

  • Peralta, Alonso Andres Hormazabal;Choi, You-Jin;Hu, Hyewon;Hu, Kyung-Seok;Kim, Hee-Jin
    • Journal of Korean Dental Science
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    • v.14 no.2
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    • pp.101-109
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    • 2021
  • Purpose: For minimally invasive procedures, three-dimensional (3D) anatomical knowledge of the structures of the face is essential. This study aimed to describe the thickness of the skin and subcutaneous tissue and depths of the facial muscles located in the infraorbital region using a 3D scanner to provide critical clinical anatomical guidelines for improving minimally invasive cosmetic procedures. Materials and Methods: The 3D scanning images of 38 Korean cadavers (22 males and 16 females; age range: 51~94 years at the time of death) were analyzed. Eight facial landmarks (P1~P8) were marked on the cadaveric faces. The images were scanned in three steps-undissected face, hemiface after skinning, and revealing the facial muscles. Student's t-test was used to identify significant differences. Result: The skin and subcutaneous tissue tended to become thicker from the upper to lower and medial to lateral aspects, and the muscles followed the same pattern as that of the most superficial located muscle and the deepest located muscles. No significant sex-related differences were found in the skin at any landmark. However, the muscles tended to be deeper in the female participants. Conclusion: The study data can serve as a basis for creating or enhancing clinical anatomy-based guidelines or improving procedures in the infraorbital region.