• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 학술대회 논문집 정보 및 제어부문
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• pp.316-318
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• 2004

In this study, the influence of electromagnetic wave effected on human body of light sensing was classified. Subjects of the eye was stimulated by the rays of LED and the measured electrical signals(EEG, EOG and ERG) in human body were compared and analyzed in the case of exposed at electromagnetic wave or not. The result show that when the subjects were not exposed at electromagnetic wave, the ratio of a wave has a large percentage in the EEG signal and the ratio of $\beta$ wave has come to good.

• 대한핵의학회지
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• 제34권3호
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• pp.159-168
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• 2000

In the 1980s, techniques to image the human subjects in a three-dimensional direction were developed. Two major techniques are SPECT (Single Photon Emission Computed Tomography) and PET (Positron Emission Tomography) which allow the detector to detect a single photon or annihilation photons emitted from the subjects injected with radiopharmaceuticals. Since the latter two techniques can measure the density of receptors, enzymes and transporters in living human, it may be very important project to develop selective methods of labeling with radionuclides and to develop new radiopharmaceuticals. There has been a considerable interest in developing new compounds which specifically bind to dopamine and serotonin receptor and transporters, and it will be thus very useful to label those compounds with radionuclides in order to gain a better understanding in biochemical and pharmacological interactions in living human. This review mentions the characteristics of radioligands for the imaging of dopamine and serotonin receptors and transporters. Although significant progress has been achieved in the development of new PET and SPECT ligands for in vivo imaging of those receptors and transporters, there are continuous needs of new diagnostic radioligands.

• 성인간호학회지
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• 제22권2호
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• pp.130-142
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• 2010

Purpose: The purpose of this study was to analyze attitude toward dignified dying of Korean students majoring in human service area. Methods: The Q-methodology which provides a method of analyzing the subjectivity of each item was used. The 34 selected Q-statements from each of 38 subjects were classified into a shape of normal distribution using a 9 point scale. The collected data was analyzed using a QUANL PC program. Results: Four types of attitude toward dignified dying from the subjects were identified. Type I is an expression type for happy emotion, Type II is a dislike type for life prolongation, Type III is a pursuit type for relationship improvement, and Type IV is a perception type for family presence. Conclusion: The results of the study indicate that integrating multi-disciplinary curriculum development related to dignified dying and death education for students majoring in human service area are needed.

• 한국가정과학회지
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• 제2권1호
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• pp.52-67
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• 1999

The primary purpose of this study was to analyze the types of home managers in association with effects of resourcefulness, communication and the conditions for effective home management＇ proposed by Shape and Winter(1991). A survey was conducted by subjects of 300 wives in Kwangju city. The statistical data were obtained by cluster analysis, one-way ANOVA, Duncan＇s test and chi-square test. Manager types based on the four conditions, resourcefulness and communication were classified into four clusters. Educational background, job status, family types, family life cycle and age difference between the oldest and the youngest child of the subjects were different from manager types. In conclusion, this study identified the four conditions of performance-condition dichotomy, timing, high level and middle range, resourcefulness, and communications in order to develop managerial capability. (Korean J Human Ecology 2(1) : 52∼67, 1999)

• 감성과학
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• 제1권1호
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• pp.93-103
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• 1998

In this paper, we present change of human sensiblity when the 26 healthy female subjects were exposed with visual picture stimulus. We used Intermational Affective Picture System as the visual stimulus. The methods are AutoRegressive(AR) spectrum which is a linear method and Return Map which is a nonlinear mithod. SR spectrum may variability(HRV). The LF/HF of HRV and the variation of Return Map were analyzed from ECG signal of the female subjects. Return Map of RR intervals were analyzed by computiong the variation. When the subjets were stimulated by the pleasant pictures, LF/HF and variation were decreased compared with unpleasant stimulus, We may obtain good parameters for the measurement of the change of human sensibility for the visual picture stimulus.

• 한국의류학회지
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• 제23권8호
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• pp.1098-1109
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• 1999

This study was to examine the effects of textiles materials and wearing types on the thermal regulation responses of human, Cotton polyester wool silk and rayon were chosen as outerwears and acetate was selected as a lining. Blouse-skirt suits blouse-slacks suits and one-piece dress made of selected textiles were examined by human trials, Tests results were as follows ; 1 When subjects wore vlouse-slacks suits Tmsk was showed the highest value. There was a significant difference on Tmsk(p<0.05) when they wore one-piece dress. The temperature of microclimate inside clothing when subjects wore blouse-slacks suits showed the highest value and one-piece dress and then blouse-skirt suits in order. For blouse-skirt suits clothing without lining showed higher temperature of the back of microclimate inside clothing than clothing with lining except cotton(p<0.1) 2. There were no significant consistency of the increasing rates of thermal insulation of garment at fabric test and human trials among polyesterand silk.

• Journal of Korean Biological Nursing Science
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• 제15권1호
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• pp.33-42
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• 2013

Purpose: The purpose of this study was to develop standard syllabuses of 4 subjects (Structure and Function of Human Body, Pathogenic Microbiology, Pathophysiology, Mechanisms and Effects of Drug) of bionursing. Methods: We developed standard syllabuses of 4 subjects through 3 step discussions and analysis. At first each committee for 4 subjects made the syllabus, after then all researchers discussed together. Finally each committee concluded final one. Committee members consisted of professors who teach that subject at nursing college. Results: Standard syllabus for Biological Nursing I-1 or Structure & Function of Human Body I consisted of 3 parts and 9 themes and for Biological Nursing I-2 or Structure & Function of Human Body II was 3 parts and 9 themes. Standard syllabus for Biological Nursing II or Pathogenic Microbiology consisted of 8 themes and Biological Nursing III or Pathophysiology consisted of 2 parts and 19 themes. Standard syllabus for Biological Nursing IV or Mechanisms & Effects of Drug consisted of 2 parts and 13 themes. Conclusion: The standard syllabuses and titles of 4 subjects of bionursing need to be disseminated to all the nursing college by Academy of Korean Biological Nursing Science. Further researches to investigate curriculum for bionursing and to identify the effects of 4 standard syllabuses were recommended.

• 의료법학
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• 제20권2호
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• pp.173-206
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• 2019

본 연구는 최근 일본의 임상연구 관련 규율의 특색을 검토한 것이다. 첫째, 우리나라와 같이 일본에서도 그 동안 연구부정에 대해서는 엄벌주의를 취하여 왔지만, 최근 일본에서는 연구윤리정책을 제재가 아닌 교육연수에 의한 연구공정성 확보로 방향을 전환하였다는 점과 2018년 4월부터 시행된 임상연구법은 임상연구에 관한 자금제공 정보의 공표를 의무화하여 임상연구에 따른 자금제공의 투명성을 높인 점 및 의학계 연구의 윤리심사의 집약화 및 피험자를 집중시켜 증례나 우수한 연구자를 모집하여 임상연구·치험을 집약화한 점, 둘째, 그 동안 역학연구에 관한 윤리지침(이하, 「역학지침」이라 함)과 임상연구에 관한 윤리지침(이하, 「임상지침」이라 함)으로 이원화되어 있었던 윤리지침을 인간을 대상으로 하는 의학계 연구에 관한 윤리지침(이하, 「통합지침」이라 함)으로 통합 정비하여 임상연구와 역학연구에 필요한 윤리지침의 중복과 흠결을 보완했다는 점 이외에도 피험자보호를 위한 리스크 평가제도를 둔 점 이외에도 평가의 선결문제인 「침습」 개념을 명확히 했다는 점에서 긍정적인 평가를 받고 있다. 임상연구관련 국제규범상의 공통적인 내용인 「위험과 이익의 평가 문제」는 연구자의 연구가 적절히 고안되었는지를 검사하는 수단이다. 이는 연구윤리위원회가 피험자에게 가해질 위험이 정당화될 수 있는지 여부를 결정하는 방법이며, 장래의 피험자가 임상시험의 참여여부를 결정하는 중요한 기준이 되기도 한다. 그러므로 피험자의 리스크 평가의 선결문제인 「침습」 개념을 명확히 정의한 것은 의미 있는 것이다. 본 연구에서는 특히 최근 일본의 임상시험에서의 연구부정방지 대책에 대한 인식의 전환, 연구심사 및 피험자의 집약화를 통환 연구의 효율성 제고, 피험자 보호를 위한 리스크 평가의 전제가 되는 「침습」 개념의 명확화와 범위의 확장 등에 관한 논점을 중심으로 검토한 것이다.

• 대한기관윤리심의기구협의회지
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• 제5권1호
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• pp.21-32
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• 2023

Purspose: The purpose of this study is to examine the meaning and definition of vulnerable subjects in clinical trials in light of domestic and international regulations and guidelines, to analyze the contents of standard operation procedures (SOPs) among advanced general hospitals in Korea that conduct clinical trials, and to examine deliberation procedures for operation plans. Methods: The study examined how vulnerable research subjects were defined and described in related regulations and the classification of vulnerable research subjects presented in the IRB/HRPP SOPs of 18 clinical trial institutions, including 11 AAHRPP-accreditated general hospitals in Korea, as well as the operation of the IRB deliberation. Results: Among all domestic and international regulations and guidelines, only the The Council for International Organization of Medical Sciences (CIOMS) guidelines explain why vulnerability is related to judgments on the severity of physical, psychological, and social harm, why individuals are vulnerable, and for what reasons. However, the classification of vulnerable subjects by institutions differed from the classification by the International Conference on Harmonization-Good Clinical Practice (ICH-GCP). A total of the 16 institutions classified children and minors as vulnerable research subjects. 14 institutions classified subjects who cannot consent freely were classified as vulnerable subjects. 15 institutions classified sujects who can be affected by the organizational hierarchy were classified as vulnerable subjects. Subjects in emergency situations were regarded as vulnerable research subjects in 8 of institutions, while people in wards, patients with incurable diseases, and the economically poor including the unemployed were categorized as vulnerable research subjects in 7, 4, and 4 of institutions, respectively. Additionally, some research subjects were not classified as vulnerable by ICH-GCP but were classified as vulnerable by domestic institutions 15 of the institutions classified pregnant women and fetuses as vulnerable, 11 classified the elderly as vulnerable, and 6 classified foreigners as vulnerable. Conclution: The regulations and institutional SOPs classify subjects differently, which may affect subject protection. There is a need to improve IRBs' classifications of vulnerable research subjects. It is also necessary to establish the standards according to the differences in deliberation processes. Further, it is recommended to maintain a consistent review of validity, assessment of risk/benefit, and a review using checklists and spokeperson. The review of IRB is to be carried out in a manner that respects human dignity by taking into account the physical, psychological, and social conditions of the subjects.

• 한국생활과학회지
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• 제18권1호
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• pp.211-221
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• 2009

The study investigated medical treatment features of patients with type 2 diabetes mellitus, their further complications, levels of diet therapy education and the status of dietary compliance. The subjects were patients who came to oriental medicine clinics in Daejon. The percentage of male was 37.5% and female was 62.7% in the subject group's sex distribution. The outbreak of the disease was most common in the age of 50's. Also 40% of the subjects had been suffering for more than 5 years. 35.7% of men and 53.7% of women had family history. All the subjects had further complications, among them hypertension was the most common. Kidney, hepatic, vascular heart diseases were followed. 85.3% of the subjects answered they already had educations about diet therapy. Those educations were given in the public health center, general and private hospitals. 32% of subjects were not practicing diet therapy. The difficulties with which patients can be faced when they take dietary education were exchange(?exchanging?) food and calculating calories. Most of the subjects tend to overlook the importance of dietary habits and show low understanding to diet therapy, which leads to low participation rate of diabetes patients. Based on these results, therefore, we can conclude that diet therapy education to the patients should be more organized and easily practicable for them. To develop educational methods which can draw patients' attention and also be more effective is the most important task.