• Title/Summary/Keyword: Human Similarity

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Genetic analysis of Campylobacter jejuni isolates from diarrhea patients in Gyeonggi-do (경기도에서 분리된 Campylobacter jejuni의 유전자 패턴 분석 연구)

  • Kim, Woon-Ho;Choi, Ok-Kyung;Jeong, Jin-A;Park, Sung-Hee;Lee, Yea-Eun;Park, Gwang-Hee;Yoon, Mi-Hye
    • Korean Journal of Microbiology
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    • v.54 no.1
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    • pp.31-37
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    • 2018
  • Campylobacter jejuni is an important food-borne pathogen causing gastroenteritis in human. We isolated 208 strains of Campylobacter jejuni from 430 diarrhea patients and food employees with 17 food-poisoning outbreaks between 2014 and 2016 in Gyeonggi area. The strains were tested for genetic relationship and the genotype distribution using PFGE and multiplex-PCR typing. Among the 47 Penner-serotypes known for C. jejuni, it was identified as a genotype consisting of 35 genotypes by multiplex-PCR typing and represented 7 genotypes (HS2, HS4A, HS8, HS15, HS29, HS41, and HS53) in the selected strain. From the PFGE analysis of 11 food-poisoning outbreaks, 5 group of PFGE profile were obtained, and genetic similarity in these clusters ranged from 61.8 to 66.6%. This study examines the genetic diversity of C. jejuni that have been separated in the Gyeonggi area through various genetic analysis methods and identifies the correlation between strains in patients who have been infected with the disease in the future.

Fall Detection for Mobile Phone based on Movement Pattern (스마트 폰을 사용한 움직임 패턴 기반 넘어짐 감지)

  • Vo, Viet;Hoang, Thang Minh;Lee, Chang-Moo;Choi, Deok-Jai
    • Journal of Internet Computing and Services
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    • v.13 no.4
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    • pp.23-31
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    • 2012
  • Nowadays, recognizing human activities is an important subject; it is exploited widely and applied to many fields in real-life, especially in health care and context aware application. Research achievements are mainly focused on activities of daily living which are useful for suggesting advises to health care applications. Falling event is one of the biggest risks to the health and well-being of the elderly especially in independent living because falling accidents may be caused from heart attack. Recognizing this activity still remains in difficult research area. Many systems equipped wearable sensors have been proposed but they are not useful if users forget to wear the clothes or lack ability to adapt themselves to mobile systems without specific wearable sensors. In this paper, we develop a novel method based on analyzing the change of acceleration, orientation when the fall occurs and measure their similarity to featured fall patterns. In this study, we recruit five volunteers in our experiment including various fall categories. The results are effective for recognizing fall activity. Our system is implemented on G1 smart phone which are already plugged accelerometer and orientation sensors. The popular phone is used to get data from accelerometer and results showthe feasibility of our method and significant contribution to fall detection.

Development of Design Space Exploration for Warship using the Concept of Negative Design (네거티브 설계 개념을 이용한 함정 설계영역탐색법 개발)

  • Park, Jin-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.9
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    • pp.412-419
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    • 2019
  • Negative space in the discipline of art defines the space around and between the subject of an image. The use of negative space is an element of artistic composition, since it is occasionally used to artistic effect as the "real" subject of an image. In painting, it is a technique that negatively touches the background of an object to be expressed, so that it gives a feeling of unique texture and silhouette by touching unnecessary parts while leaving necessary parts. As in art, negative space in a design can also be useful to identify an image of infeasible design ranges with a straightforward view. Similarity between two disciplines leads to the introduction of the negative space concept for design space exploration. A rough design space exploration using statistics and visual analytics may support more efficient decision-making, and can provide meaningful insights into the direction of early-phase system design. For this, the approach guarantees dynamic interactions between visualized information and human cognitive systems. Visual analytics is useful to summarize complex and large-scale data. It is useful for identifying feasible design spaces, as well as for avoiding infeasible spaces or highly risky spaces. This paper investigates the possible use of the negative space concept by using an application example.

Image Quality Analysis when applying DLIR Reconstruction Techniques in NECT CT (NECT CT에서 DLIR 재구성기법 적용 시 화질분석)

  • Yoon, Joon;Kim, Hyeon-Ju
    • Journal of the Korean Society of Radiology
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    • v.16 no.4
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    • pp.387-394
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    • 2022
  • 120 kVp FBP reconstruction image standard by using raw data after scanning by changing tube voltage among the NECK CT protocols that are broad applied in clinical practice using a human phantom including thyroid gland The usefulness of the DLIR reconstruction technique was investigated. As a result, CTDIvol decreased when the DLIR reconstruction technique was applied, and in particular, the image quality obtained under the same standard scanning conditions at a lower dose for ASIR-V and DLIR reconstruction was reached than when FBP was applied at the same kVp In addition, as a result of SNR and CNR analysis, the DLIR reconstructed image was analyzed with high SNR and CNR values, and SSIM analysis, the SSIM index of the 100 kVp, DLIR reconstructed image was measured to be close to 1, and it was analyzed that the similarity of the reconstructed image to the original image was high (p>0.05). If the results of this study are used to supplement clinical image evaluation and further develop an algorithm applicable to various anatomical structures, it is thought that it will be useful for clinical application as it is possible to maintain the image quality while lowering the examination dose.

Forecasting the Changes in Construction Market by Analyzing General·Specialty Contractors' Perception on Business Area Abolition (종합·전문건설사업자의 상호시장진출 의향 및 참여방식 분석을 통한 종합·전문간 업역철폐에 따른 건설시장 변화 예측)

  • Kim, Sung-Il;Chang, Chul-Ki
    • Korean Journal of Construction Engineering and Management
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    • v.24 no.2
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    • pp.88-97
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    • 2023
  • The purpose of this study is to forecast future changes in the construction market following the reorganization of the construction production system by analyzing the possible market size in which general contractors and specialty contractors may participate in each other, and by carrying out a survey. The ratio of correlation between general construction and specialty construction industries was derived by analyzing the relevance of work area of general contractors and specialty contractors, the similarity of registration standards, and the market in which general contractors and specialty contractors may be able to mutually participate. In order to overcome the limitation of previous studies which analyze the changes in construction market based on the statistical data, and to analyze in more detail the impact of reorganization of construction production system from market participants' view, a survey targeting general contractors and specialty contractors for their willingness and method of participating in the mutual market was conducted. As a result of the survey, it was found that 52% of general contractors were willing to participate in the specialized construction market and 55.1% of specialty contractors were willing to participate in the general construction market. It was found that there was a high willingness to participate in the earthworks, reinforced concrete works, facility maintenance and management, water and sewage facility works, and interior works, and high competition is expected for projects with a scale of 500 million to less than 3 billion won. Through this study, it will be possible for general and specialty contractors to understand the changes in the construction market due to the reorganization of the construction industry production system, and to respond effectively to these changes.

Phylogenetic and expression analysis of the angiopoietin-like gene family and their role in lipid metabolism in pigs

  • Zibin Zheng;Wentao Lyu;Qihua Hong;Hua Yang;Ying Li;Shengjun Zhao;Ying Ren;Yingping Xiao
    • Animal Bioscience
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    • v.36 no.10
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    • pp.1517-1529
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    • 2023
  • Objective: The objective of this study was to investigate the phylogenetic and expression analysis of the angiopoietin-like (ANGPTL) gene family and their role in lipid metabolism in pigs. Methods: In this study, the amino acid sequence analysis, phylogenetic analysis, and chromosome adjacent gene analysis were performed to identify the ANGPTL gene family in pigs. According to the body weight data from 60 Jinhua pigs, different tissues of 6 pigs with average body weight were used to determine the expression profile of ANGPTL1-8. The ileum, subcutaneous fat, and liver of 8 pigs with distinct fatness were selected to analyze the gene expression of ANGPTL3, ANGPTL4, and ANGPTL8. Results: The sequence length of ANGPTLs in pigs was between 1,186 and 1,991 bp, and the pig ANGPTL family members shared common features with human homologous genes, including the high similarity of the amino acid sequence and chromosome flanking genes. Amino acid sequence analysis showed that ANGPTL1-7 had a highly conserved domain except for ANGPTL8. Phylogenetic analysis showed that each ANGPTL homologous gene shared a common origin. Quantitative reverse-transcription polymerase chain reaction analysis showed that ANGPTL family members had different expression patterns in different tissues. ANGPTL3 and ANGPTL8 were mainly expressed in the liver, while ANGPTL4 was expressed in many other tissues, such as the intestine and subcutaneous fat. The expression levels of ANGPTL3 in the liver and ANGPTL4 in the liver, intestine and subcutaneous fat of Jinhua pigs with low propensity for adipogenesis were significantly higher than those of high propensity for adipogenesis. Conclusion: These results increase our knowledge about the biological role of the ANGPTL family in this important economic species, it will also help to better understand the role of ANGPTL3, ANGPTL4, and ANGPTL8 in lipid metabolism of pigs, and provide innovative ideas for developing strategies to improve meat quality of pigs.

Spatial Similarity between the Changjiang Diluted Water and Marine Heatwaves in the East China Sea during Summer (여름철 양자강 희석수 공간 분포와 동중국해 해양열파의 공간적 유사성에 관한 연구)

  • YONG-JIN TAK;YANG-KI CHO;HAJOON SONG;SEUNG-HWA CHAE;YONG-YUB KIM
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.28 no.4
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    • pp.121-132
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    • 2023
  • Marine heatwaves (MHWs), referring to anomalously high sea surface temperatures, have drawn significant attention from marine scientists due to their broad impacts on the surface marine ecosystem, fisheries, weather patterns, and various human activities. In this study, we examined the impact of the distribution of Changjiang diluted water (CDW), a significant factor causing oceanic property changes in the East China Sea (ECS) during the summer, on MHWs. The surface salinity distribution in the ECS indicates that from June to August, the eastern extension of the CDW influences areas as far as Jeju Island and the Korea Strait. In September, however, the CDW tends to reside in the Changjiang estuary. Through the Empirical Orthogonal Function analysis of the cumulative intensity of MHWs during the summer, we extracted the loading vector of the first mode and its principal component time series to conduct a correlation analysis with the distribution of the CDW. The results revealed a strong negative spatial correlation between areas of the CDW and regions with high cumulative intensity of MHWs, indicating that the reinforcement of stratification due to low-salinity water can increase the intensity and duration of MHWs. This study suggests that the CDW may still influence the spatial distribution of MHWs in the region, highlighting the importance of oceanic environmental factors in the occurrence of MHWs in the waters surrounding the Korean Peninsula.

Biomarkers for Canine Mammary Tumors (반려견 유선종양 바이오 마커)

  • Chan-Ho Lee;Young Sun Choi;Suk Jun Lee;Sung-Hak Kim
    • Journal of Life Science
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    • v.34 no.6
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    • pp.434-441
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    • 2024
  • Mammary gland tumors are the most common tumors detected in non-spayed female dogs and pose a significant clinical challenge. Due to the strong similarity between canine mammary tumors (CMT) and human breast cancer (HBC), biomarkers identified in HBC can also be detected in CMT. These biomarkers have been shown to offer valuable insights into early diagnosis, prognosis, and treatment strategies. The purpose of this article is to provide a concise overview of CMT biomarkers based on the current literature. Traditional treatments for CMT in dogs typically begin with surgery, followed by chemotherapy, radiotherapy, or hormonal therapy. However, these treatments alone are not always fully effective. A diagnostic biomarker can detect the presence of a disease or the characteristics of a disease and classify an individual's status. Prognostic biomarkers focus on predicting the expected progression, recurrence, or survival of the disease in patients. By utilizing advances in understanding the mechanism of canine-specific mammary gland tumors, the estimation of biomarkers offers hope for improved outcomes in cancer patients. Novel technologies, such as single-cell RNA sequencing analysis, could provide a valuable resource for deciphering intra- and inter-tumoral heterogeneity. This review paper explores current research on CMT biomarkers and suggests directions for their development.

Cesium Adsorption Properties of Activated Carbon with Oxygen Functional Groups Introduced by Ozonation Treatment (오존 처리에 의해 산소 작용기가 도입된 활성탄소의 세슘 흡착 특성)

  • Eunseon Chae;Chung Gi Min;Chaehun Lim;Young-Seak Lee
    • Applied Chemistry for Engineering
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    • v.35 no.1
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    • pp.23-28
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    • 2024
  • Cesium is a potential toxic contaminant due to its high solubility, which allows it to easily penetrate the human body and potentially induce cancer or DNA mutations. In this study, oxygen functional groups were introduced on activated carbons (ACs) by ozone treatment to enhance the cesium adsorption capacity. As the ozone treatment time increased, the oxygen content on the ACs surface increased. Subsequently, the electrostatic interaction between ACs and cesium enhanced, resulting in higher cesium ion adsorption efficiency across all samples. In particular, the sample treated with ozone for 7 minutes at an internal ozone concentration of 50000 ppm had roughly 12% greater oxygen functional group content and the highest cesium removal effectiveness (97.6%). Meanwhile, samples treated for 5 minutes showed a 0.3% cesium removal rate difference compared to those treated for 7 minutes, which was caused by the surface chemical similarity of the two samples due to the reactive characteristics of ozone gas. However, the cesium adsorption performance of ozonated activated carbon seems to be mainly influenced by the amount of oxygen functional groups introduced to the surface, although the specific surface area and pore structure of the activated carbon are also important.

A Study on the Adolescent Sibling Relationship through Photovoice (포토보이스를 통해 본 청소년기 형제자매관계에 관한 연구)

  • Kim, Jiseul;Jun, Mikyung
    • Journal of Korean Home Economics Education Association
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    • v.36 no.2
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    • pp.15-31
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    • 2024
  • This study employs photovoice research methodology to investigate adolescents' experiences in sibling relationships and to analyze the impact of sibling interactions on their development and growth. The participants comprised eight high school students with one sibling (four males and four females) residing in the Incheon region. The research process encompassed several stages: participant recruitment, orientation, photovoice activity (focus group interviews), data analysis, and conclusion derivation. During the photovoice activity, participants engaged in a narrative process of photographing, interpreting, and discussing their experiences. The narratives were categorized into four primary themes: structure and environment, emotional interactions, roles, and parental subsystems. The conclusions drawn from the study are as follows: First, the similarity formed in sibling relationships during adolescence contributes to psychological stability. Second, roles and expectations based on birth order can cause stress for adolescents, indicating the need for equitable role adjustments within the family. Third, conflict in sibling relationships is crucial for enhancing problem-solving and social relationship skills. Lastly, consistent parenting attitudes significantly affect the emotional well-being of siblings. This study emphasizes the significance of fostering a deeper understanding of human development and family relationships through an exploration of adolescent sibling dynamics within home economics education.