• Environmental Analysis Health and Toxicology
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• 제20권4호통권51호
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• pp.259-271
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• 2005

Engineered nanoparticles exhibit a variety of unique and tunable chemical and physical properties. These unique properties make the nanoparticles central components and widespread potential applications in nanoindustry. However, the potential toxicities of nanoparticles have not been fully evaluated. Recently, the impacts of nanoparticles to human and environment became the emerging issue of toxicology. In this article, physicochemical properties and toxicities of carbon nanotube, fullerene, quantum dots, and other types of nanomaterials were reviewed and the strategy of risk assessment were suggested based on the frame of chemical assessment.

• 환경영향평가
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• 제4권3호
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• pp.1-8
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• 1995

In generally speaking, the purpose of Environmental Impact Assessment(EIA) is to give the environment its due place in the decision-making process by clearly ealuating the environmental consequence of a proposed activity before action is taken. The introduction of conventional EIA is to be seen as an end product of a very long evolutionary process, starting with rudimentary but evolving pollution control measures for air, water, noise, land and chemicals, each governed by separate, and separately administered pieces of legislation. In EIA process, the measures of status, scoping, proposed mitigation and communication have not been very quantitative in their significancy. Of course, the determinations have uncertainity in the implications for significant impacts. To improve the determination of significant impacts, some more comprehensive methodologies of EIA has been proposed with the concepts of risk analysis in the proposed projects. The concepts of risk analysis has been introduced to the expression of human health impairment due to environmental pollutants since the early 1980's. The risk analysis being meant by the statistical significance of impact has a process quantitatively considering uncertainities and importances of ecological systems and human health as well. The process of risk analysis shows assessment, doseresponse in toxicity, exposure assessment and risk characterization. With the risk assessment, it could be suggested for the proper measurements against their anticipated risk in the EIA. This paper deals the priciples developing process and application of the risk-based analysis in EIA.

• 한국환경보건학회지
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• 제36권4호
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• pp.294-305
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• 2010

This study estimated the health risk of heavy metals in particulate matter $(PM)_{2.5}$ in a Gwangyang industrial complex. The $PM_{2.5}$ containing heavy metal was collected from January to November, 2008 using a denuder air sampler and by IC (Ion Chromatograph). The risk assessment was performed in a four-step process; hazard identification, exposure assessment, dose-response assessment and risk characterization. In the hazard identification process, $Cr^{6+}$, Ni, As, and Pb were categorized as human carcinogens and probable human carcinogens, while Ti, Mn, Se, P, $Cr^{3+}$, Cu, and Zn were not classified as human carcinogens. It was found that the excess cancer risk by Central Tendency Exposure (CTE) of $Cr^{6+}$ and As in $PM_{2.5}$ was > $10^{-6}$, and the total excess cancer risk posed by carcinogen heavy metals in $PM_{2.5}$ was > $10^{-6}$. It was also determined that the total hazard index by CTE of non-carcinogen heavy metals in $PM_{2.5}$ was <1. Taken together, these results indicate a high cancer risk associated whit inhalation of heavy metal-containing$PM_{2.5}$ in industrial areas.

• 한국환경보건학회지
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• 제50권2호
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• pp.146-156
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• 2024

Background: Children who use playground facilities are exposed to potential risks due to the high concentration of heavy metals contained in the finishing materials of facilities in children's playgrounds. Objectives: The purpose of this study was to investigate the concentration of heavy metals in the finishing materials of outdoor children's playgrounds where harmful heavy metals exist in Gwangju and to conduct human risk assessment for children and adults by age to find the risks and limitations. Methods: The bottom and top layers of double-painted paint were peeled off and collected together from the finishing materials of children's play facilities such as slides, swings, and seesaws in 147 children's parks in Gwangju. Heavy metals were analyzed using ICP-OES, etc., and human risk assessment was performed using the concentrations of heavy metals. Results: Based on 1.0E-04, which requires legal regulation, CTE was found to pose a carcinogenic risk for preschool children and no carcinogenic risk for the rest of the age groups. However, RME showed that both men and women of all ages had a carcinogenic risk. For reference, when the carcinogenic risk was based on 1.0E-06, CTE was found to pose a carcinogenic risk from infants to elementary school students, and RME was found to have a carcinogenic risk in all age groups. It was judged that there is a non-carcinogenic risk if the non-carcinogenic risk exceeds 1 based on the hazard index (HI) 1. In CTE, there was no non-carcinogenic risk, and RME for preschooler males (1.49E+00) and females (1.56E+00) were found to have non-carcinogenic risk. Conclusions: This study was meaningful in that it examines the differences in the current management of heavy metals concentration standards and potential carcinogenic and non-carcinogenic risks to the human body and discusses the relationship between heavy metals and human health effects.

• 한국물환경학회지
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• 제29권2호
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• pp.165-169
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• 2013

Freshwater fish intake is a critical parameter for deriving water quality criteria and water quality standards for protection of human health based on human health risk assessment. Although the freshwater fish intake parameter should be accurate and representative of Korean fish consumption for the water quality criteria to be reliable, data are limited in Korea and have low reliability. In this study, Korean National Health and Nutrition Examination Survey data from 2008-2010 were analyzed to reevaluate freshwater fish consumption. Based on these results, an average consumption rate of 3.0 g/day per person, a $90^{th}$ percentile consumption rate of 0.0 g/day per person, an average consumption rate of 65.7 g/day per fish consumer, and a $90^{th}$ percentile consumption rate of 153.4 g/day per fish consumer were proposed for derivation of water quality criteria using a conservative approach and various exposure scenarios.

• Environmental Engineering Research
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• 제24권1호
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• pp.82-90
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• 2019

Meeting the regulations based on the short-term leaching tests may not necessarily assure the environmental and human health safety of reusing mine wastes. This study investigated heavy metal leachability of four metal mine waste samples (e.g., Z, Y, H, and M) and human health risk of reusing them as construction materials. The heavy metal leachability did not depend on the total heavy metal contents. For example, the Z sample contained greater amounts of As and Fe than Zn, but the leachates contained only Zn at a detectable level. This can be attributed to the crystalline structure and heavy metal fractions of the mine wastes. The leaching test results suggested that the four mine waste samples are potentially reusable. But the Z and M samples reused in industrial areas imposed carcinogenic risks. This was largely attributed to As that is exposed via dermal contact. The Y and H samples reused in residential areas imposed carcinogenic risk. The major exposure route was the ingestion of crops grown on the mine wastes and Cr was the major concern. The two-stage assessment involving leaching tests and risk assessment can be used to promote safe reuse of mine wastes.

• Journal of Dairy Science and Biotechnology
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• 제29권2호
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• pp.69-73
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• 2011

Food borne pathogens are a growing concern for human health and food safety throughout the world. Milk and dairy products are commonly associated with spoilage or contamination from a wide variety of physical, microbial, and chemical hazardous. Microbiological risk analysis consists of three components: risk assessment, risk management, and risk communication, and overall objective of this process is ultimately public health protection. The microbiological risk assessment is useful tool to evaluate food safety as it is based on a scientific approach. In addition risk assessment process includes quantitative estimation of the probability of occurrence of microbial hazards to evaluate more accurate human exposure. The aim of this study is to review the microbiological risk assessment on the prevalence of bacterial foodborne pathogens in milk and dairy products.

• Environmental Analysis Health and Toxicology
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• 제17권4호
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• pp.347-355
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• 2002

As concerns on the effects of soil contamination on human health have grown, more efforts have been made to quantify the effects. One of such efforts is the development of risk assessment methodology. The fundamental objectives of this approach is to investigate the alternative options that reduce the risk of hazardous chemicals results from environmental pollution, which will eventually lead to an accomplishment of removement of identified toxicants in polluted environment. The U.S. EPA Risk Assessment guidance for the superfund (RAGS) provides a methods for assessing the health risk of contaminated soils and determining the preliminary remediation goals (PRGs). Using this approach, we assessed the health risk and preliminary remediation goals of petroleum contaminated site in Kyounggi province.

• Journal of Microbiology and Biotechnology
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• 제22권2호
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• pp.256-263
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• 2012

A strain of bacterium producing antifungal antibiotic was isolated and identification of the strain was attempted. We could identify the bacterium as being a Bacillus sp., based on morphological observation, physiological characteristics, and 16S rDNA sequence analysis, thus leading us to designate the strain as Bacillus sp. AH-E-1. The strain showed potent antibiotic activity against phytopathogenic and human pathogenic fungi by inducing mycelial distortion and swelling and inhibiting spore germination. The antibiotic metabolite produced by the strain demonstrated excellent thermal and pH (2-11) stability, but was labile to autoclaving. From these results, we could find a broader antifungal activity of Bacillus genus. Isolation and characterization of the active agent produced by the strain are under progress.

• 환경정책연구
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• 제7권1호
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• pp.1-29
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• 2008

환경부에서 추진하고 있는 "환경보건법" 이 2008년 2월 국회를 통과함에 따라 향후 법 제13조(건강영향 항목의 추가 평가 등) 제1항의 규정에 따라 사전환경성검토 또는 "환경영향평가법"에 따른 환경영향평가의 대상이 되는 행정계획 및 개발사업 중 대통령령으로 정하는 행정계획 및 개발사업에 대하여는 검토 평가 항목에 환경유해인자가 국민건강에 미치는 영향을 추가하여 평가하도록 하는 건강영향평가제도가 시행될 것으로 예상된다. 이에 본 연구에서는 주요 개발사업 중 인체 건강에 미칠 영향이 클 것으로 예상되는 매립장을 대상으로, 매립장에서 배출되는 매립가스의 호흡노출로 인한 인체위해성평가를 실시하여 향후 추진될 건강영향평가제도의 국내 적용 가능성을 파악하고자 하였다. 이를 위해 첫째, 미국 EPA의 매립장 배출가스 산출 추천모델인 LandGEM v. 3.02(Landfill Air Emissions Estimation Model v. 3.02)를 이용하여 매립장에서 배출되는 매립가스의 배출량을 산정하였고, 대기확산모델인 K-SCREEN을 수행하여 매립장 주변지역에 미치는 확산농도를 예측하였다. 마지막으로 K-SCREEN 모델을 통해 예측된 유해 오염물질의 확산농도를 토대로 발암성 물질에 대해서는 여러 노출변수들을 적용하여 인체노출량을 산출한 후 발암위해도 평가를 수행하였고 비발암성 물질에 대해서는 위해도지수를 계산하였다. 본 연구에서 수행한 매립가스의 호흡노출로 인한 인체위해성평가 기법은 향후 매립장 조성사업에 대한 건강영향평가 시행시 의사결정자들과 일반대중이 과학적 기반 위에서 합리적인 의사결정을 하는데 필요한 정보를 제공하는데 있어 적용이 가능할 것으로 사료된다. 또한, 본 연구에서 제시한 몇 가지 연구의 한계점들은 관련 연구자들의 체계적인 연구를 통해 극복할 필요가 있으며, 이러한 한계점들이 개선된다면 좀 더 신뢰성 있는 결과를 산출할 수 있을 것으로 판단된다.