• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.18 no.9
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• pp.905-912
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• 2008

Notion sickness is well known to be caused by long time exposure to the very low frequency motion in the multiple axes of human body Since the vestibular system for the perception of low frequency motion is located in the head, accurate measurement of 6 degree of freedom head motion is of great importance. In this study, the measurement system consisting of a safety helmet and 9 translational accelerometers was constructed for the estimation of 3 translational and 3 rotational motions of human head. Since estimation errors of 3 rotational components can be significantly magnified even by small offset of the sensitivity axis from the geometric center of an accelerometer, accurate measurement of sensitivity axis must be preceded. The method for accurate estimation of the offset was proposed, and the effect of offset on the estimation of angular acceleration was investigated.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.4919-4923
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• 2014

Background: To investigate the effect of celecoxib on telomerase activity and apoptosis in a human laryngeal squamous carcinoma cell line (Hep-2 cells). Materials and Methods: The growth inhibition rate of Hep-2 cells in vitro was measured by MTT assay, and apoptosis by TUNEL assay and flow cytometry (FCM). The TRAP-ELISA method was used to determine telomerase activity in Hep-2 cells. The mRNA expression of human telomerase RNA component(hTR), human telomerase reverse transcriptase (hTERT) and human telomerase-associated protein(hTEP1) was determined by RT-PCR assay. Expression of Bax and Bcl-2 proteins was assessed by Western blotting. Results: Celecoxib can inhibit proliferation and induce apoptosis in a dose- and time-dependent manner, repress telomerase activity, decrease hTERT mRNA and Bcl-2 protein expression and increase Bax protein expression, PGE2 had no effect on telomerase. Conclusions: Celecoxib had the antiproliferative and pro-apoptotic effect in Hep-2 cells. Apoptosis was accompanied by a decrease in telomerase activity which was directly correlated with hTERT mRNA and up-regulation of Bax/Bcl-2. Bcl-2 may thus play an important role in telomerase activity as well as apoptosis.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.3
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• pp.409-426
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• 2001

Absorbed power of the human head radiated from a 900 MHz portable phone and temperature rise are computed using FDTD(Finite-Difference Time-Domain) method. For this computation the 5 layered media for the human head modeling and the monopole antenna attached to metallic box for the portable phone are used. To reflect the real circumstances typical sizes of human heads and portable phones are considered in the calculation. The length of monopole antenna is 8.15 cm, and the output power of a phone is 600 mW. Under the predetermined model the distribution of 1 g, 10 g averaged SAR and temperature rise rate over the human head are calculated, from which it was found that the position of maximum SAR is near at the head skin surface, not deep places far into the head. The position of the highest temperature is located far from the head skin more than that of the maximum SAR occured. The averaged SAR and temperature along the distance between the head and phone are calculated according to seperation distance between the head and phone.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.8 no.6
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• pp.665-680
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• 1997

The specific absorption rate (SAR) distributions in various models of the human head have been analyzed when the models are exposed to 350 MHz and 900 MHz plane waves. The numerical analysis is performed with the finite-difference time-domain (FDTD) method. A homogeneous sphere including a cylinderical neck, a homogeneous head shaped model, and a heterogeneous realistic model are used as models of human head. The incident plane wave used for these calculations is propagating from the front to the back or from the back to the front of the head model, with its E-field vector orientation being parallel to the major length of the body. The specific findings are: 1) the average SARs of the three models are similar mutually but the local SARs of them differ greatly mutually; 2) the power is deposed more deeply in the head at 350 MHz, which is roughly the resonant frequency of a human head, than at 900 MHz; 3) for a plane wave propagating from the back, "hot spot" is found in the neck region, not in the head; 4) for a plane wave propagating from the front, "hot spot" is found in the nose at 900 MHz, and in the upper part of the lip and the jaw region at 350 MHz.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.36T no.2
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• pp.70-76
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• 1999

With the recent increase in the use among young children of portable telephone public concern regarding potential health hazards due to a hot spot appearing inside the infant head, has been growing. Since the biological hazards due to RF exposure are caused mainly by a temperature-rise in tissue, the effect of localized SAR for portable telephones should also be related to the temperature-rise in the human head. In this paper, it was measured that in the actual use of portable telephone the temperature of the local tissue in the human-head change. As a result, it should be noted that the mean temperature of human-body and localized tissue is rising from beginning call. However the temperature variation of localized tissue is recovered rapidly as normal temperature, although the mean temperature of human-body rising continuously at ending call of portable telephone.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.38 no.6
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• pp.684-691
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• 2001

In this paper, we design and implement a system which recognizes and tracks a human head on a sequence of images. In this paper, the color of the skin and ellipse modeling is used as feature vectors to recognize the human head. And the modified time-varying edge detection method and the vertical projection method is used to acquire regions of the motion from images with very complex backgrounds. To select the head from the acquired candidate regions, the process for thresholding on the basis of the I-component of YIQ color information and mapping with ellipse modeling is used. The designed system shows an excellent performance in the cases of the rotated heads, occluded heads, and tilted heads as well as in the case of the normal up-right heads. And in this paper, the combinational technique of motion-based tracking and recognition-based tracking is used to track the human head exactly even though the human head moves fast.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.12
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• pp.6083-6086
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• 2012

Background: The aim of this study was to screen for human papillomavirus (HPV) infections in head and neck squamous cell carcinomas (HNSCCs) using P16 immunostaining. Materials and Methods: A retrospective study was performed on 150 samples from patients diagnosed with HNSCCs. HPV status was determined using $p16^{INK4A}$. Results: 31 of the 150 (20.7%) HNSCCs were HPV positive. Conclusions: A large proportion of HNSCCs in Sudan are associated with HPV infection. The fact that the prevalence of HPV is high among Sudanese patients with head and neck cancers (HNC) has obvious implications for vaccine therapy.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2001.11a
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• pp.319-324
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• 2001

An anatomical head and a multi-layered spherical head with a half-wave handset antenna have been analysed and compared using the Finite-Difference Time-Domain (FDTD) and the Eigenfuntion Expansion Method (EEM), respectively. The analysis shows that results from a simple spherical head with a half-wave antenna can be used to predict the main antenna radiation patters as well as estimates of the peak SAR in a handset user's head. Various representative design data are presented using a six-layered spherical head with a half-wave antenna at 900 MHz

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.4157-4162
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• 2012

Background: Novel prognostic biomarkers or therapeutic molecular targets for laryngeal squamous cell carcinoma (LSCC) are an urgent priority. We here sought to identify multiple novel LSCC-associated genes. Methods: Using high-density microarray expression profiling, we identified multiple genes that were significantly altered between human LSCCs and paired normal tissues. Potential oncogenic functions of one such gene, DCUN1D5, were further characterized in vitro. Results: Our results demonstrated that DCUN1D5 was highly expressed in LSCCs. Overexpression of DCUN1D5 in vitro resulted in 2.7-fold increased cellular migration, 67.5% increased invasive capacity, and 2.6-fold increased proliferation. Endogenous DCUN1D5 expression was decreased in a time-dependent manner after genotoxic stress, and silencing of DCUN1D5 by siRNA decreased the number of cells in the S phase by 10.2% and increased apoptosis by 11.7%. Conclusion: Our data suggest that DCUN1D5 in vitro might have vital roles in DNA damage response, but further studies are warranted to assess its significance in vivo.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.35D no.7
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• pp.1-8
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• 1998

In this paper, the radiation characteristics of a bar-type tranceiver are analyzed by using FDTD method and the effectiveness of the analysis method is verified by comparing the calculated data with experimental data. The effects of human head and hand on the radiation characteristics of fold-type transceiver are analyzed. In order to observe the effects of human head and hand on the input impedance and far-field radiation pattern, a fold-type transceiver with .lambda./4 monopole antenna wrapped by human hand operating in the proximity of hea dis modeled an analyzed.