• 한국ITS학회 논문지
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• 제6권2호
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• pp.45-56
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• 2007

미래 사회로 갈수록 대중교통을 연계하기 위한 환승센터의 기능 및 규모가 확대됨에 따라 환승센터 내에서 이용자를 대상으로 경로를 안내하는 시스템의 필요성이 제기되고 있다. 그러나 도로에서의 차량을 대상으로 한 최적경로에 관한 모형은 많이 제시되고 있는 반면 건물 내에서 보행자를 위한 최적경로에 대한 연구는 미미하다. 따라서 본 연구는 복합환승센터 내에서 승용차를 이용하는 개인이 지하주차장에서 환승센터 내 대중교통 수단 이용을 위한 승강장이나 상가 시설로 이동하는 최적의 경로를 제시할 수 있는 모형개발을 주요내용으로 하였다. 건물 내 최적경로 모형은 다익스트라(Dijkstra) 알고리즘을 기본으로 하여 거리의 최소비용을 산정하고, 여기에 이동시간, 피로감, 쾌적도와 대기시간 등의 요소를 순위합, 산술합 방법 등을 통해 적용하여 객관성을 부가하였다. 또한 대중교통 수단의 이용자들의 성향이 반영된 Neuro-Fuzzy 모형을 통하여 환승센터 내 환승하는 이용자에게 최적의 교통수단을 제시하고, 그 해당 수단의 승강장까지 최적경로를 제시함으로써 모형의 효율성을 높였다. 마지막으로 가상의 시나리오들를 통하여 개발 모형의 효율성 검증하였다. 검증결과 개발모형을 통했을 경우 그렇지 않을 경우보다, 수직이동 경로차이의 시나리오에서 약 75%, 수평이동 경로차이의 시나리오에서 약 $24.5{\sim}107.7%$ 더 효율적으로 나타났다.

• 한국식품영양과학회지
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• 제31권5호
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• pp.856-861
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• 2002

본 연구는 녹차의 섭취기간에 따른 질병 발현 정도를 조사하기 위하여 경상남도 하동군에 거주하는 주민 92명을 대상으로 설문조사를 통하여 이루어졌다. 조사대상자들의 녹차 섭취기간에 따라 녹차를 마시지 않는 대조군과 10년 미만 녹차 섭취군 및 10년 이상 녹차 섭취군의 3분위로 나누어 녹차의 장기간 섭취가 건강관련 변인과 식습관에 미치는 영향을 분석하였다. 그 결과는 다음과 같다. 조사대상자의 일반적 특성은 전체 대상자 중 남자가 41명, 여자가 51명이었으며, 평균연령은 대조군이 62.0세, 2분위 60.1세, 3분위 57.2세로 나타났다. 건강관련 생활습관으로 음주여부는 1분위에서 45.5%, 2분위 36.1%, 3분위 37.5%가 음주를 하는 것으로 나타나, 녹차를 마시는 집단에서의 음주비율이 낮게 나타났다. 마시는 술의 종류로는 소주가 가장 많은 비중을 차지하였으며, 음주의 빈도는 1, 3분위에서 주 5～6회 마신다가 50%이상, 2분위는 주 1～2회가 53.8%로 가장 많이 차지하였다. 흡연여부는 80%정도가 거의 담배를 피우지 않는 것으로 조사되어 바람직한 흡연행동을 나타내었다. 신체활동정도는 모든 집단이 농사일에 직접 참여함으로써 왕성한 활동정도를 보였으며, 건강보조식품은 잘 섭취하지 않는 것으로 조사되었다. 질병유병률을 조사한 결과, 충치는 1분위 9%, 2분위 27%, 3분위 36%가 충치가 없다고하여 녹차의 장기간 섭취가 충치 예방에 다소간의 영향을 미쳤음을 알 수 있었다. 감기는 각 분위에서 77%, 87%, 76%로 감기를 잘 앓지 않는 것으로 조사되었으나 유의성은 없었다. 골다공증에 관한 문진 결과 29%, 64%, 100%순으로 정상이라고 응답하였다. 그러나 골다공증 검사율이 저조하여 녹차의 효과를 비교하기는 힘들었다. 식습관 점수는 녹차를 장기간 섭취할수록 유의적으로 좋은 점수를 나타내었다. 본 연구의 대상자들은 녹차를 접할 기회가 많고 주로 질병의 예방 및 개선을 목적으로 마시고 있었기에 녹차의 기능성에 대해서 많은 관심과 기대를 보여주고 있었다. 게다가 본 조사의 결과, 녹차의 장기간 음용이 충치, 골다공증과 같은 질병의 예방 및 식습관 향상에 영향을 미침을 알 수 있었고 나아가 녹차의 섭취를 증가시키기 위해서는 차 이외의 다양한 음식과 생활용품으로의 개발이 필요함을 알 수 있었다.

• 동의생리병리학회지
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• 제18권2호
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• pp.528-533
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• 2004

The immune system acts to protect the host from infectious agents that exist in the environment and from other noxious insults. The immune system has two functional divisions: the innate and the acquired. Both components involve various factors such as cytokines. A number of methodologies exist to assess aspects of immune function. There are large inter-individual variations in many immune functions even among the healthy. Genetics, age, gender, smoking habits, habitual levels of exercise, alcohol consumption, diet, stage in the female menstrual cycle, stress, history of infections and vaccinations, and early life experiences are likely to be important contributors to the observed variation. While it is clear that individuals with immune responses significantly below 'normal' are more susceptible to infectious agents and exhibit increased infectious morbidity and mortality, it is not clear how the variation in immune function among healthy individuals relates to variation in susceptibility to infection. Oriental medicine is an important factor contributing to immune competence. The author investigated the immune enhancement effects of Bojungikkitanggami-bang (BITB). The forced swimming test (FST) has been used as a screening model for new immune enhancement agents. In the present study, the author investigated the effects of BITB on FST and blood biochemical parameters related to fatigue, glucose (Glc); blood urea nitrogen (BUN); lactate dehydrogenase (LDH); creatinine; and total protein (TP). The author found that BITB (1 g/kg) significantly reduced the immobility time in the FST compared to the control. In addition, the contents of Glc, LDH, BUN, TP in the blood serum were increased in BITB (1g/kg)-fed group. Also, the author investigated the effects of BITB on the production of cytokines in human T-cell line, MOLT-4 cells. BITB (1 mg/ml) significantly increased the interferon (IFN)-vproduction compared with media control (about 2.2-fold for IFN-γ) at 24 h. However, BITB has not affect the production of IL-2 and IL-4. In addition, BITB increased the protein expression level of IFN-γ in MOLT-4 cells. Thus, BITB may have therapeutic value in generating or enhancing immune function in a clinical setting.

• KIEAE Journal
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• 제15권2호
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• pp.19-26
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• 2015

Purpose: Maximizing human comfort in design of medical environments depends immensely on specialized architects particularly critical care design; the study proposes Evidence-Based Design as an apparent analog to Evidence-Based Medicine. Healthcare facility designs are substantially based on the findings of study in an effort to design environments that augment care by improving patient safety and being therapeutic. On SPSS (Statistical Package for Social Science) t-test is applied to simulate two independent variables of PDR (Pre Design-Research) and POE (Post- Occupancy Evaluation). PDR is conducted on relatively new hospital Hallym University Dongtan Sacred Heart Hospital to analyse visibility from researchers' point of view, here the ICU is arranged in I-Shape. POE is applied on Dongguk University Ilsan Hospital to simulate walking on LogWare where two NS are designed based on L- Shape and Seoul St. Mary's Hospital, The Catholic University of Korea where five NS are functional for ICU Intensive Care Unit, Surgical Intensive Care Unit (SICU), Medical Intensive Care Unit (MICU), Critical Care Unit (CCU), Korean Oriental Medical Care Unit which are mostly arranged in U-Shape, and walking pattern is recognized to be in a zigzag path. Method: T-Test is applied on two dependent communication variables: walkability and visibility, with confidence interval of 95%. This study systematically analyses the Nurse Station (NS) typo-morphology, and simulates nurse horizontal circulation, by computing round route visits to patient's bed, then estimating minimum round route on LogWare stop sequence software. The visual connectivity is measured on depth map graphs. Hence the aim is to reduce staff stress and fatigue for better patients care by minimizing staff horizontal travel time and to facilitate nurse walk path and support space distribution by increasing effectiveness in delivering care. Result: Applying visibility graph and isovist field on space syntax on I- Shape, L- Shape and U- Shape ICU (SICU, MICU and CCU) configuration, I-shape facilitated 20% more patients in linear view as they stir to rise from their beds from nurse station compared to U-shape. In conclusion, it was proved that U-Shape supply minimum walking and maximum visibility; and L shape provides just visibility as the nurse is at pivot. I shape provides panoramic view from the Nurse Station but very rigorous walking.

• 한국패션뷰티학회지
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• 제3권3호
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• pp.31-40
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• 2005

The reason that aromatherapy began to draw attention again as the alternative therapy is because the essential oils that are used for aromatherapy not only allow the human body to maintain homeostasis but also have an effect on curing a mental feeling of fatigue and because these efficacies and effects are proceeding with being proved scientifically. Also, with coming to be high in a voice of concern about severally side effects that the modern medicine and the synthetic chemistry have, the aromatherapy came to be paid attention as the replacement therapy that can substitute for and supplement this. In particular, at the time of requiring a study on a substance to substitute for this after having been announced in Japan for 1998 a risk of Zincpyrithione that is being used as a component of dandruff treatment, it is thought that the aroma oil that was known for having an anti-dandruff effect has a merit of being easy in a user's access, thus it will be effective in curing the symptom of dandruff. Accordingly, this study conducted the following experiment in a bid to examine whether the aroma oil has the anti-microbial effect on the actual malassezia. First of all, it measured the minimum concentration of aroma oil in which the growth of malassezia is inhibited, by carrying out MIC(Minimum Inhibition Concentration) test in terms of anti-microbial activity against Malassezia furfur KCTC 7744 while using oils of Patchouli, Rosemary, Lavender, and Tea tree among aroma oils that are being used for dandruff treatment. As a result of that, Tea tree oil has the most excellent anti-microbial activity, and the measurement result of anti-microbial activity was shown in order of Lavender oil>Rosemary oil>Patchouli oil. Next, it carried out the is actually eased by applying Tea tree oil directly to the scalp of dandruff. In consequence of the experiment, the massage of Tea tree oil indicated the result of relieving the symptoms of dandruff such as scale, itch, pain, inflammation, and sebum, and among these symptoms of dandruff, it was shown to be most effective in easing itch. Especially, this clinical experiment was indicated that the massage of Tea tree oil has the most effect on relieving itch of targets with a dry-skin type who had no experience of dandruff treatment.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.5917-5935
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• 2012

Background: Hepatitis C virus (HCV) causes acute and chronic human hepatitis infection and as such is an important global health problem. The virus was discovered in the USA in 1989 and it is now known that three to four million people are infected every year, WHO estimating that 3 percent of the 7 billion people worldwide being chronically infected. Humans are the natural hosts of HCV and this virus can eventually lead to permanent liver damage and carcinoma. HCV is a member of the Flaviviridae family and Hepacivirus genus. The diameter of the virus is about 50-60 nm and the virion contains a single-stranded positive RNA approximately 10,000 nucleotides in length and consisting of one ORF which is encapsulated by an external lipid envelope and icosahedral capsid. HCV is a heterogeneous virus, classified into 6 genotypes and more than 50 subtypes. Because of the genome variability, nucleotide sequences of genotypes differ by approximately 31-34%, and by 20-23% among subtypes. Quasi-species of mixed virus populations provide a survival advantage for the virus to create multiple variant genomes and a high rate of generation of variants to allow rapid selection of mutants for new environmental conditions. Direct contact with infected blood and blood products, sexual relationships and availability of injectable drugs have had remarkable effects on HCV epidemiology. Hundreds of thousands of people die each year from hepatitis and liver cancer caused by HCV virus infection. Approximately 80% of patients with acute hepatitis C progress into a chronic disease state leading to serious hepatic disorders, 10-20% of which develop chronic liver cirrhosis and hepatocellular carcinoma. The incubation period of HCV is 6-8 weeks and the infection is often asymptomatic so it is very hard to detect at early stages, making early treatment very difficult. Therefore, hepatitis C is called a "silent disease". Neutralizing antibodies are produced against several HCV proteins during infection but the virus mutates to escape from antibodies. Some patients with chronic hepatitis C may have some symptoms such as fatigue, muscle aches, nausea and pain. Autoimmune and immunecomplex-mediated diseases have also been reported with chronic HCV infection.

• 한방재활의학과학회지
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• 제18권3호
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• pp.147-156
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• 2008

Objectives : Oriental Medicine Music Therapy is a new way of treating and preventing various diseases and promoting health by means of music specially picked and designed to produce Qi(氣) fitting to an individual person in the areas of the structure of human body, physiological function, pathological change, diagnosis and treatment. Therefore, it can facilitate the efficiency of the treatment much better and faster than only with herb or acupuncture. Equilibrium between body and mind is its originality. Methods : A 38-year old man came to hospital suffering from left side weakness, dysarthria because of cerebral infarction. After one week's medication in the part of neurology, he was sent to the oriental medicine music therapy center, and he took ten times' medical treatments once a day. Before and after the treatments, implementing 'Ink foot print analysis', as for the movement capacity and walking of left side weakness, these results are acquired. Results and Conclusions : 1. Before the oriental medicine music therapy, except the acceleration and deceleration section, within three meters, a right foot's step was measured 30.55 cm and a left foot was measured 15.2 cm, and the step distance was 15.2 cm. After the 10 times treatments, the right foot's step was 112.6 cm, the left foot's step was 113 cm, and the step distance improved to 51.8 cm. 2. The normal person's average step is about 38 cm, and it could be decreased owing to a decreptitude, pain, fatigue, and the weakness of the legs. In spite of all, from the increased 50 cm step measurement with the patient's body condition, it means that his movement capacity is recovered. 3. In the measurement of walking time, before 10 times treatments, it took 46.35 seconds within 6M, but after the treatments, it increased to 7.47 seconds as same as a normal person's walking speed. 4. In insomnia, and the abnormality of a facial muscle, it shows lots of improvement, and even the accuracy of a pronunciation, but despite of the 10 times treatments, the 'ㄹ(r)' sound placed under a vowel is unclear. 5. Before the 10 times' treatments, he can move the left side shoulder with pain and cannot move below the left elbow. After the treatments, the pain was disappeared, and he was able to move over 60 cm without pain. And improving of the movement of fingers, he can beat over 8 times with a drumstick.

• 한국조경학회지
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• 제32권2호
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• pp.11-24
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• 2004

The purpose of this study is to present data on the human activities responding to the physical environment of ‘Ulsan’s Grand Parks by evaluating user behavior and activity, visiting motivations, and user satisfaction. This study was conducted using multi-methods such as interviews and questionnaires surveys. The main findings of this study can be summarized in six parts as follows: \circled1 Behavior patterns showed that the users visited the park left within 30 minutes and the frequency of visits was 1 or 2 times per week. They spent their time mostly on ‘walking’ and ‘picnicking’. The users visited regardless of the seasons or the day of the week. \circled2 The priorities for improvements were analyzed as follows: the users expressed their demands for ‘shadowing facilities’ like shelters and pergolas because they used these facilities frequently. Also, the users would like an ‘event program’, ‘sign system’ and ‘guide program’. \circled3 Analysis of the the user’s perception of the park showed that they perceive the park as ‘representative source of the landscape and open space in Ulsan and place for making contact with nature. \circled4 In examining the visiting motivations of the users of Ulsan Grand Park, it was revealed that people use the park for ‘time with family and friends’, ‘to escape from city life’, ‘to relieve fatigue. As a result of factor analysis, 4 factors were identified such as ‘physical motive(MF1)’, ‘exploratory motive(MF2)’, ‘social motive(MF3)’ and ‘emotional motive(MF4). \circled5 Park users’ evaluation for park facilities showed that people are satisfied with most of the facilities and especially, they have high level of satisfaction for ‘footpaths’, ‘squares’ and ‘picnicspace’. The evaluation of the park user’s of activity reveals that they are content with nearly all the variables. Especially, they have high level of satisfaction for the variables of ‘convenience for dynamic activities’, ‘making of a beautiful atmosphere, ‘accessibility from the outside’ and, ‘convenience in group activitie. Factor analysis of the park user’s of activity revealed 5 factors such as ‘convenience and interest factor (AF1)’, ‘park maintenance, management and use program(AF2)’, ‘visual beauty(AF3)’, ‘safety and accessibility(AF4)’ and ‘crowding(AF5)’. \circled6 Regression analysis was employed to get the predictor factors of overall satisfaction with a result of 60.0%($R^2$). The variance was explained as ‘quality of the picnic space’, ‘convenience and interest factor while using the park’, ‘park program for maintain and management in the park’, ‘visually beauty while using the park’, ‘safety and accessibility of the parks’, ‘quality of the pond’, ‘crowding’, ‘quality of the square’.

• Journal of Dairy Science and Biotechnology
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• 제34권3호
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• pp.181-186
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• 2016

Kaempferia parviflora (Krachaidam, Zingiberaceae) is used as a traditional Thai medicine for treating various ailments, including allergy, fatigue, sexual dysfunction, and ulcer. Moreover, it is also used to promote longevity and as a nerve tonic. The aim of this study was to develop functional yoghurt containing Kaempferia parviflora and to examine the physicochemical characteristics of yoghurt supplemented with different concentration of K. parviflora. To this end, we examined the pH and sensory evaluation of yoghurt containing K. parviflora. The pH of this yoghurt decreased whereas the TA increased with incubation time (up to 5 h) without altering the amounts of K. parviflora added. In the sensory evaluation, the taste, flavor, color, and overall acceptability decreased in proportion to the amount of K. parviflora added. Among the experimental group, high scores were achieved by yoghurt containing 1% K. parviflora compared with that by the control group. We conclude there is an urgent need for additional research on the production of this multi-functional yogurt (with properties including anti-obesity and anti-inflammatory), using an optimum concentration of K. Parviflora.

• 근관절건강학회지
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• 제29권1호
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• pp.69-80
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• 2022

Purpose: To identify research trends in the Journal of Muscle and Joint Health. Methods: In total, 315 studies published between 2008 and 2020 in the Journal of Muscle and Joint Health were reviewed using analysis criteria developed by the authors Results: Most participants were adults or older adults, they mostly had arthritis. The types of research design were descriptive research (46.4%), quasi-experimental design (21.9%), randomized controlled trial (1.9%), and qualitative research (4.1%). The occupation of most authors was professor in universities (61.0%). Data were collected mostly in hospitals (41.6%) or communities (24.4%) using a questionnaire (52.4%). Written consent was obtained at 75.6% and 47.9% of studies were approved by the Institutional Review Board (IRB). The instruments measuring physical concepts such as pain, flexibility, sense of balance and fatigue were mostly used. The most common interventions in experimental studies were physical interventions, with the main being exercise. Key words were categorized into four nursing meta-paradigms: human, health, environment and nursing. The most frequently reported key words were included in the health domain. The most frequently used key words were physical intervention, older patient, osteoarthritis, pain and depression. Conclusion: The results suggest that more research studies targeting various age groups related to muscle and joint health are required. Additionally there is a need to increase the number of qualitative studies, randomized experimental studies, and systematic review studies. It is necessary to pay attention to compliance with research ethics publication regulations.