• Korean Journal of Microbiology
• /
• v.43 no.4
• /
• pp.237-242
• /
• 2007

One of the chief characteristics of the retrovirus life cycle is the appearance of provirus caused by integration of viral genome into the host cell genome, and its delivery stably to the next generation as a part of host germ line. This stable form is called endogenous retrovirus (ERV) and expressed by exogenous or endogenous factors. HERVs and MuERVs are present in humans and mice correspondingly, and their expressions frequently cause diseases. Several diseases such as cancer, autoimmunity and neurological disorders are related with HERVs. Therefore, various strategies should be established for the development of effective therapies for the suffering patients.

• The Journal of Asian Finance, Economics and Business
• /
• v.8 no.12
• /
• pp.9-17
• /
• 2021

Globalization is an economic process responsible for the increase of interdependence of world economies. It enhances the mobility of national resources internationally via the integration of markets, trade and investments with minimal barriers to slow the flow of products and services. Although globalization has some positive impacts on the economy, it is said to be a factor in the decline of income inequality of the participating countries. However, the results of previous studies on the relationship between globalization and income inequality are inconclusive. This suggests that there are other factors influencing the relationship between the two variables. The purpose of this study is to examine the role of intelligence (IQ) in the globalization-income inequality relationship. This study employs the threshold regression technique and cross-nation observations from 117 sample nations for the period 1980-2016. The results show that the impact of globalization on income inequality in a nation relies on its IQ level. The results imply that economic globalization has a negative impact on income inequality in nations with lower IQ levels. It widens the gap between the poor and rich. While in nations with higher IQ levels, it seems to not have any significant impact on income distribution.

• Journal of the Korea Society of Computer and Information
• /
• v.23 no.11
• /
• pp.103-109
• /
• 2018

This paper presents an idea and framework to automate a full cycle business process management and re-engineering by integrating traditional business process management systems, process mining, data mining, machine learning, and simulation. We build our framework on the cloud-based platform such that various data sources can be incorporated. We design our systems to be extensible so that not only beneficial for practitioners of BPM, but also for researchers. Our framework can be used as a test bed for researchers without the complication of system integration. The automation of redesigning phase and selecting a baseline process model for deployment are the two main contributions of this study. In the redesigning phase, we deal with both the analysis of the existing process model and what-if analysis on how to improve the process at the same time, Additionally, improving a business process can be applied in a case by case basis that needs a lot of trial and error and huge data. In selecting the baseline process model, we need to compare many probable routes of business execution and calculate the most efficient one in respect to production cost and execution time. We also discuss the challenges and limitation of the framework, including the systems adoptability, technical difficulties and human factors.

• Journal of Distribution Science
• /
• v.20 no.3
• /
• pp.95-106
• /
• 2022

Purpose: This study aims to verify the effects of omnichannel characteristics on pleasure, resistance and repurchase intention in the omnichannel situation in order to provide the innovative commercial business. Research design, data and methodology: The study examined relations between research concepts centered on previous studies, set hypotheses, developed a research model, and verified the model through a questionnaire survey. A total of 297 questionnaires were used for the final analysis, excluding the questionnaires showing insincere or outliers. Results: First, Omnichannel showed multi-dimensional characteristics consisting of consistency, innovation, economy, and integration. Second, innovation and economic feasibility had a positive effect on pleasure. Third, only economic feasibility had a negative effect on user resistance. Fourth, consumers' shopping pleasure had a negative effect on user resistance. Fifth, repurchase intention of consumers was positively affected by innovation. Conclusions: This research contributed to extend academic framework of distribution research by examining causal relationship through adoption of economic and innovation factors as new characteristics from the integrated perspective beyond the research frame of the existing omnichannel distribution environment. Companies should provide meaningful experiences by resolving concerns about side effects caused by human-computer interaction and providing smart information that matches the products most suitable for consumer needs.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.6
• /
• pp.2489-2493
• /
• 2015

Background: Loss of heterozygosity (LOH) on chromosomal regions is crucial in tumor progression and this study aimed to identify genome-wide LOH in pancreatic cancer. Materials and Methods: Single-nucleotide polymorphism (SNP) profiling data GSE32682 of human pancreatic samples snap-frozen during surgery were downloaded from Gene Expression Omnibus database. Genotype console software was used to perform data processing. Candidate genes with LOH were screened based on the genotype calls, SNP loci of LOH and dbSNP database. Gene annotation was performed to identify the functions of candidate genes using NCBI (the National Center for Biotechnology Information) database, followed by Gene Ontology, INTERPRO, PFAM and SMART annotation and UCSC Genome Browser track to the unannotated genes using DAVID (the Database for Annotation, Visualization and Integration Discovery). Results: The candidate genes with LOH identified in this study were MCU, MICU1 and OIT3 on chromosome 10. MCU was found to encode a calcium transporter and MICU1 could encode an essential regulator of mitochondrial $Ca^{2+}$ uptake. OIT3 possibly correlated with calcium binding revealed by the annotation analyses and was regulated by a large number of transcription factors including STAT, SOX9, CREB, NF-kB, PPARG and p53. Conclusions: Global genomic analysis of SNPs identified MICU1, MCU and OIT3 with LOH on chromosome 10, implying involvement of these genes in progression of pancreatic cancer.

• Journal of the HCI Society of Korea
• /
• v.4 no.1
• /
• pp.29-34
• /
• 2009

The food culture has been advanced with technical developments. The technical advances of food refrigeration and refrigerated transport system enable people to enjoy raw and fresh foods in the middle of dessert and in current days the development of information technology helps people to get variable information as like the information of food stuffs, freshness, the history of cooking, other useful information. We need to research the information architecture of food culture, which means Information technology grafts on the food culture, to provide diverse services that information technology utilized. As the first step of our research, we define the context of food culture for integration of food culture and Information technology, and find out the relationships between each factors. This research is considered the food culture as a medium between human to human relationships and the food, and redefined it with a relationship viewpoint. We've selected Yam cha that is one of the famous foods in southern China as a research item and referenced data that we researched with students in Guangzhou College of Art, China.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.8 no.1
• /
• pp.235-242
• /
• 2013

For people with disabilities, getting a job makes it possible to advocate their own human rights, to improve their self-esteem and self-efficacy, to narrow economic, psychological and social divide between them and those without disabilities and ultimately to attain social integration. According to recent statistical data, there was an increase in the weight of people with disabilities, but their economic activities were on the wane, and it's required to explore what curbs the employment of people with disabilities to find feasible solutions. The purpose of this study was to examine influential factors for the economic activities of people with disabilities. The subjects in this study were the selected people with disabilities in the metropolitan area, on whom a survey was conducted to make an empirical analysis. The findings of the study were as follows: The people with disabilities engaged in less economic activities when they were basic livelihood security recipients, when they were older, and when they were female. And those who underwent job training and who were certified technicians were more likely to participate in economic activities. Therefore differentiated policy setting is required to boost the economic activities of people with disabilities after their general characteristics, characteristics as human resources and characteristics related to vocational training are carefully analyzed. As for general characteristics, whether they are basic livelihood security recipients or not should be considered to assess the degree of their poverty, and their gender, age and presence or absence of spouses should all be taken into account. In terms of vocational training, their certificates and job training experience should be investigated.

• Journal of Technologic Dentistry
• /
• v.35 no.3
• /
• pp.243-257
• /
• 2013

Purpose: This study aims to analyze the factors affecting the dropout intentions of the dental technology students of a college. Methods: The subject of this study was 76 freshmen and 74 sophomores of dental technician major in an anonymous college. Results from the questionnaire called K-vision diagnosis program were computed by means of t-test, One-Way ANOVA, and correlation analysis. Results: 1. Total points of the drop out intention came to 782.14 points. Of the five categories concerned with the drop out intention, complain in college satisfaction(50.12points) was the highest and department satisfaction(47.51points) was the lowest. Of 16 subcategories, complaining in administrative supporting system proved the highest as 50.80 points and Inquiry to Professor the lowest(45.56 points). 2. Among the general characteristic gender (p<. 01), student group (p<.01), and credit (p<.05) made a meaningful statistical difference; no statistical significance was found in grade, admission, and dwellings. 3. Of the five categories, statistical significance was shown as follows; Department satisfaction (p<.01), College satisfaction (p<.05) under gender, Department satisfaction (p<.05) in grade, Academic integration (p<.01), Department satisfaction (p<.01) in credit. No statistical meaning was found in admission and dwellings. 4. Statistical significance was found under 16 subcategories as follows: Career identification(p<.01), Academic support system(p<.01), Social activity II(p<.05) in gender area, Inquiry to professor(p<.01), Learning(p<.05), Understanding learning I(p<.05) in grade area, Learning(p<.001), Career identification(p<.001), Understanding learning I(p<.01), Understanding learning II(p<.01), Inquiry to professor (p<.01), Learning ability (p<.05), Occupation (p<.05), Social Activity II(p<.05), Administrative support system (p<.05) in student group area, Credit (p<.001), Career identification (p<.01), Understanding learning I(p<.05) in credit area; admission and dwellings was statistically meaningless. 5. Of the 5 categories academic integration (r=.766) was most relevant to the dropout intention of the subjects and followed by department satisfaction (r=.735), college satisfaction (r=.554), service acceptability (r=.373), and statistical significance was shown as p<.01. Conclusion: Considering the results of this study, we are in a pressing need for the introduction of policies and programmes aiming at preventing the dropout rates of the dental technician majors at college. In tandem with this, qualitative and viable human resource management of the dental technicians should be implemented.

• Physical Therapy Korea
• /
• v.7 no.2
• /
• pp.1-19
• /
• 2000

Decreased equilibrium in standing and walking is a common problem associated with hemiparesis secondary to cerebral vascular accident. In patients with hemiplegia, postural sway is increased and often displaced laterally over the non-affected leg, reflecting asymmetry in lower extremity weight bearing during standing balance. Human balance is a complex motor control task, requiring integration of sensory information, neural processing, and biomechanical factors. Limits of stability (LOS) is a one of the biomechanical factors. The purposes of this study were to establish the influence of asymmetrical weight-bearing on the LOS of independent ambulatory hemiparetic patients. The subjects of this study were 29 hemiparetic patients (18 males, 11 females) being treated as admitted or out patients at Young-Nam University Hospital and Taegu Catholic University Hospital, all of whom agreed to participate in the study. Participants were asked to lean and displace their center of gravity (COG) as far as possible in directions to the sides and front of the body. The LOS and weight-bearing ratio were measured with a Balance Performance Monitor (BPM) Dataprint Software Version 5.3. In order to assure the statistical significance of the results, the independent t-test and a Pearson's correlation were applied at the .05 and .01 level of significance. The results of this study were as follows: 1) There were statistically significant differences in anteroposterior LOS according to the cause of brain demage (p<.01). 2) There were statistically significant differences in mediolateral LOS according to the hemiparetic side (p<.05). 3) There were statistically significant differences in anteroposterior and mediolateral LOS according to the brain operation (p<.01). 4) The mediolateral LOS significantly correlated with weight-bearing ratio (p<.01).

• Journal of Institute of Control, Robotics and Systems
• /
• v.19 no.7
• /
• pp.646-652
• /
• 2013

EU's Galileo project is a market-based GNSS (Global Navigation Satellite System) that is under development. It is expected that Galileo will provide the positioning services based on new technologies in 2020s. Because Galileo E1 signal for OS (Open Service) shares the same center frequency with GPS L1 C/A signal, CBOC (Composite Binary Offset Carrier) modulation scheme is used in the E1 signal to guarantee interoperability between two systems. With E1 signal consisting of a data channel and a pilot channel at the same frequency band, there exist several options in designing signal acquisition for Assisted-Galileo receivers. Furthermore, compared to SNR worksheet of Assisted-GPS, some factors should be examined in Assisted-Galileo due to different correlation profile and code length of E1 signal. This paper presents SNR worksheets of Galileo E1 signals in E1-B and E1-C channel. Three implementation losses that are quite different from GPS are mainly analyzed in establishing SNR worksheets. In the worksheet, hybrid long integration of 1.5s is considered to acquire weak signal less than -150dBm. Simulation results show that the final SNR of E1-B signal with -150dBm is 19.4dB and that of E1-C signal is 25.2dB. Comparison of relative computation shows that E1-B channel is more profitable to acquire the strongest signal in weak signal environment. With information from the first satellite signal acquisition, fast acquisition of the weak signal around -155dBm can be performed with E1-C signal in the subsequent satellites.