• Structural Engineering and Mechanics
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• 제6권3호
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• pp.347-362
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• 1998

In this study an improved design method for the traditional A-type(or V-type) offshore template platform system was proposed to mitigate the vibration induced by the marine environmental loadings and the strong ground motions of earthquakes. A newly developed material model was combined into the structural system and then a nonlinear dynamic analysis in the time domain was carried out. The analysis was focused on the displacement and rotation induced by the input wave forces and ground motions, and the mitigation effect for these responses was evaluated when the viscoelastic damping devices were applied. The wave forces exerted on the offshore structures are based on Stokes fifth-order wave theory and Morison equation for small body. A step by step integration method was modified and used in the nonlinear analysis. It was found that the new design approach enhanced with viscoelastic dampers was efficient on the vibration mitigation for the structural system subjected to both the wave motion and the strong ground motion.

• 한국의상디자인학회지
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• 제22권4호
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• pp.49-62
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• 2020

This research investigates how interest develops across a set of tasks within a course defined by a specific knowledge domain. The current study examined the relationships among self-concept, self-efficacy, Korea-related factors, and evaluation, in the context of learning about the Hanbok costume at Chinese universities. A survey (n=300) was conducted using an online survey website (www.sojump.com) from the 1st to the 25th of June. The structural equation model (SEM) analysis, including total and specific forms of self-evaluation with Hanbok courses, showed that self-concept was positively associated with self-efficacy. Conversely, K-culture interest and K-country image did not significantly affect self-efficacy in clothing, but positively affected Hanbok's self-efficacy. Meanwhile, the more self-efficacy perceived, the higher the level of evaluation. Overall, our findings imply that supporting the students' Korean culture interest, country image perception, and self-concept for regulation can enhance self-evaluation and self-realization success. Theoretical and practical implications for Hanbok courses are discussed.

• BMB Reports
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• 제40권4호
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• pp.571-576
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• 2007

Three anti-apoptosis genes, Ls-iap2, iap3 and p49 were found in Leucania separata multiple nuclear polyhedrovirus. Amino acid sequence homology of Ls-IAP2 and Ls-IAP3 with Op-IAP2 and Op-IAP3 from Orgyia pseddotsugata MNPV were 20% and 42%, while that of Ls-P49 is 28% with Sl-P49 from Spodoptera littorolis MNPV. Ls-IAP2 contains one baculoviral IAP repeat (BIR) domain followed by a RING domain, while Ls-IAP3 contains two BIRs and a RING. Ls-P49 contains a reactive site loop, predicted cleavage site (KKLD$^{74}{\downarrow}$G) that is different from Sl-P49 (TVID$^{94}{\downarrow}$G). Expressed Ls-iap3 or Ls-p49 under presence of actinomycin D in SF9 cells, DNA ladder assayrevealed that Ls- IAP3 or Ls-P49 could block the apoptosis of SF9 cells induced by actinomycin D. Replication of p35 deficient-mutant Autographa californica MNPV in SF9 cells was also rescued when Ls-iap3 or Ls-p49 was expressed transiently. No anti-apoptotic activity was observed for Ls-IAP2. The results showed that both of Ls-IAP3 and Ls-P49 were functional apoptotic suppressors in SF9 cells.

• Parasites, Hosts and Diseases
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• 제54권6호
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• pp.711-717
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• 2016

Toxoplasma gondii is an obligate intracellular parasite that stimulates production of high levels of proinflammatory cytokines, which are important for innate immunity. NLRs, i.e., nucleotide-binding oligomerization domain (NOD)-like receptors, play a crucial role as innate immune sensors and form multiprotein complexes called inflammasomes, which mediate caspase-1-dependent processing of $pro-IL-1{\beta}$. To elucidate the role of inflammasome components in T. gondiiinfected THP-1 macrophages, we examined inflammasome-related gene expression and mechanisms of inflammasome-regulated cytokine $IL-1{\beta}$ secretion. The results revealed a significant upregulation of $IL-1{\beta}$ after T. gondii infection. T. gondii infection also upregulated the expression of inflammasome sensors, including NLRP1, NLRP3, NLRC4, NLRP6, NLRP8, NLRP13, AIM2, and NAIP, in a time-dependent manner. The infection also upregulated inflammasome adaptor protein ASC and caspase-1 mRNA levels. From this study, we newly found that T. gondii infection regulates NLRC4, NLRP6, NLRP8, NLRP13, AIM2, and neuronal apoptosis inhibitor protein (NAIP) gene expressions in THP-1 macrophages and that the role of the inflammasome-related genes may be critical for mediating the innate immune responses to T. gondii infection.

• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2741-2744
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• 2016

The CKLF-like MARVEL transmembrane domain-containing family (CMTM) is a novel family of genes first reported at international level by Peking University Human Disease Gene Research Center. The gene products act between chemokines and the transmembrane-4 superfamily. Located in several human chromosomes, the CMTMs CKLF and CMTM1 to CMTM8 may be unregulated in tumors and act as potential tumor suppressor genes with important roles in the immune, male reproductive and hematopoietic systems. In-depth studies in recent years established a close relation between CMTMs and tumorigenesis and metastasis. The CMTM family has a significant clinical value in diagnosis and treatment of diseases linked to tumors and the immune system.

• Structural Engineering and Mechanics
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• 제29권2호
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• pp.135-154
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• 2008

The moving vehicle loads on a bridge deck is one of the most important live loads of bridges. They should be understood, monitored and controlled before the bridge design as well as when the bridge is open for traffic. A MOM-based algorithm (MOMA) is proposed for identifying the timevarying moving vehicle loads from the responses of bridge deck in this paper. It aims at an acceptable solution to the ill-conditioning problem that often exists in the inverse problem of moving force identification. The moving vehicle loads are described as a combination of whole basis functions, such as orthogonal Legendre polynomials or Fourier series, and further estimated by solving the new system equations developed with the basis functions. A number of responses have been combined, some numerical simulations on single axle, two axle and multiple-axle loads, being either constant or timevarying, have been carried out and compared with the existing time domain method (TDM) in this paper. The illustrated results show that the MOMA has higher identification accuracy and robust noise immunity as well as producing an acceptable solution to ill-conditioning cases to some extent when it is used to identify the moving force from bridge responses.

• Structural Engineering and Mechanics
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• 제29권2호
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• pp.155-169
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• 2008

A MOM-based algorithm (MOMA) has been developed for moving force identification from dynamic responses of bridge in the companion paper. This paper further evaluates and investigates the properties of the developed MOMA by experiment in laboratory. A simply supported bridge model and a few vehicle models were designed and constructed in laboratory. A series of experiments have then been conducted for moving force identification. The bending moment and acceleration responses at several measurement stations of the bridge model are simultaneously measured when the model vehicle moves across the bridge deck at different speeds. In order to compare with the existing time domain method (TDM), the best method for moving force identification to date, a carefully comparative study scheme was planned and conducted, which includes considering the effect of a few main parameters, such as basis function terms, mode number involved in the identification calculation, measurement stations, executive CPU time, Nyquist fraction of digital filter, and two different solutions to the ill-posed system equation of moving force identification. It was observed that the MOMA has many good properties same as the TDM, but its CPU execution time is just less than one tenth of the TDM, which indicates an achievement in which the MOMA can be used directly for real-time analysis of moving force identification in field.

• Nuclear Engineering and Technology
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• 제53권6호
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• pp.1821-1833
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• 2021

The gas-liquid counter-current flow limitation (CCFL) is closely related to efficient and safety operation of many equipment in industrial cycle. Air-water countercurrent flow experiments were performed in a tube with diameter of 25 mm to understand the triggering mechanism of CCFL. A parallel electrode probe was utilized to measure film thickness whereby the time domain and frequency domain characteristics of liquid film was obtained. The amplitude of the interface wave is small at low liquid flow rate while it becomes large at high liquid flow rate after being disturbed by the airflow. The spectral characteristic curve shows a peak-shaped distribution. The crest exists between 0 and 10 Hz and the amplitude decreases with the frequency increase. The analysis of visual observation and characteristic of film thickness indicate that two flooding mechanisms were identified at low and high liquid flow rate, respectively. At low liquid flow rate, the interfacial waves upward propagation is responsible for the formation of CCFL onset. While flooding at high liquid flow rate takes place as a direct consequence of the liquid bridging in tube due to the turbulent flow pattern. Moreover, it is believed that there is a transition region between the low and high liquid flow rate.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제18권1호
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• pp.192-210
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• 2024

Most frequency-domain remote sensing image watermarking algorithms embed watermarks at random locations, which have negative impact on the watermark invisibility. In this study, we propose an adaptive watermarking scheme for remote sensing images that considers the information complexity to select where to embed watermarks to improve watermark invisibility without affecting algorithm robustness. The scheme converts remote sensing images from RGB to YCbCr color space, performs two-level DWT on luminance Y, and selects the high frequency coefficient of the low frequency component (HH^Y₂) as the watermark embedding domain. To achieve adaptive embedding, HH^Y₂ is divided into several 8*8 blocks, the entropy of each sub-block is calculated, and the block with the maximum entropy is chosen as the watermark embedding location. During embedding phase, the watermark image is also decomposed by two-level DWT, and the resulting high frequency coefficient (HH^W₂) is then embedded into the block with maximum entropy using α- blending. The experimental results show that the watermarked remote sensing images have high fidelity, indicating good invisibility. Under varying degrees of geometric, cropping, filtering, and noise attacks, the proposed watermarking can always extract high identifiable watermark images. Moreover, it is extremely stable and impervious to attack intensity interference.

• Smart Structures and Systems
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• 제20권2호
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• pp.115-126
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• 2017

The modal identification of large civil structures such as bridges under the ambient vibrational conditions has been widely investigated during the past decade. Many operational modal analysis methods have been proposed and successfully used for identifying the dynamic characteristics of the constructed bridges in service. However, there is very limited research available on reliable criteria for the robustness of these identified modal parameters of the bridge structures. In this study, two time-domain operational modal analysis methods, the data-driven stochastic subspace identification (SSI-DATA) method and the covariance-driven stochastic subspace identification (SSI-COV) method, are employed to identify the modal parameters from field recorded ambient acceleration data. On the basis of the SSI-DATA method, the modal contribution indexes of all identified modes to the measured acceleration data are computed by using the Kalman filter, and their applicability to evaluate the robustness of identified modes is also investigated. Here, the benchmark problem, developed by Hong Kong Polytechnic University with field acceleration measurements under different excitation conditions of a cable-stayed bridge, is adopted to show the effectiveness of the proposed method. The results from the benchmark study show that the robustness of identified modes can be judged by using their modal contributions to the measured vibration data. A critical value of modal contribution index of 2% for a reliable identifiability of modal parameters is roughly suggested for the benchmark problem.