• Journal of the Institute of Electronics Engineers of Korea SC
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• v.42 no.3 s.303
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• pp.47-52
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• 2005

Obstructive Sleep Apnea (OSA) is a representative symptom of sleep disorder caused by the obstruction of upper airway. Because OSA causes not only excessive daytime sleepiness and fatigue, hypertension and arrhythmia but also cardiac arrest and sudden death during sleep in the severe case, it is very important to detect the occurrence and the frequency of OSA. OSA is usually diagnosed through the laboratory-based Polysomnography (PSG) which is uncomfortable and expensive. Therefore researches to improve the disadvantages of PSG are needed and studies for the detection of OSA using only one or two parameters are being made as alternatives to PSG. In this paper, we developed an algorithm for the detection of OSA based on Heart Rate Variability (HRV). The proposed method is applied to the ECG data sets provided from PhysioNet which consist of learning set and training set. We extracted features for the detection of OSA such as average and standard deviation of 1 minute R-R interval, power spectrum of R-R interval and S-peak amplitude from data sets. These features are applied to the input of neural network. As a result, we obtained sensitivity of $89.66\%$ and specificity of $95.25\%$. It shows that the features suggested in this study are useful to detect OSA.

• Journal of Korean Medical Ki-Gong Academy
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• v.10 no.1
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• pp.130-157
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• 2007

The purpose of this research is to seek for efficient health maintenance device and to suggest desirable daily habit, based on the inquiry on interrelationship between workers' daily lives and their heartbeat change level. The paper survey about general features, case history and daily habits was conducted on workers during medical examination in Jeollabukdo, and examined their change of heartbeat as well. The results of research deducted from data analysis are as follows; 1. There found very positive interrelations between time-domain analysis and frequency-domain analysis, and MHR and LF/HF ratio had negative connection with other analyses. 2. The recipient showed high time-domain analysis when they are younger, have worked shorter or have spouse, and it contributes to stable sympathetic nerve and parasympathetic nerve as it stimulates autonomic nervous system. 3. According to the result of frequency-domain analysis, recipients showed higher TP and LF when they are younger, and the highest HF when they are under 34.The level of VLF was higher for university graduates than the ones who finished high school. The recipients showed higher TP and HF when they don't have spouse, and lower TP, LF and HF when they have worked longer. 4. The level of RMSSD and TSRD was high for the people who don't have case history, and HF was high when they don't have any disease in progress. 5. According to the result concerning correlation of daily habits with time-domain analysis and frequency-domain analysis, cigarette, alcohol and sleeping hours don't affect heartbeat change, but the ones who regularly workout showed higher result in every analysis. It shows that the autonomic nervous system of recipients who regularly exercise response more actively. The result mentioned above suggests that the change of heartbeat is a direct index which shows the change of autonomic nervous system, and it depends on the exercise the most. Thus, workout is proved to be the best method in order for workers to take care of their health.

• Journal of Oriental Neuropsychiatry
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• v.14 no.2
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• pp.183-189
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• 2003

Hysterical aphonia is one of the frequent symptoms in conversion disorders. If it has a recent onset, a manifest induced factor, and a good premorbid adaptation, and another mental disorder is not accompanied, its prognosis is good. We report one case of hysterical aphonia that was bad prognosis. This patient was suffering traumatic event before and after onset, and major depressive disorder was accompanied. Having hysterical aphonia, the patient who had no progress after over an years medicine therapy and often felt strong suicidal urge, was successfully treated by TFT(Thought field therapy) and oriental medicine therapy. Several case studies on hypnotic cure of hysterical aphonia has been reported but they are uncommon internally and have good prognosis. In addition, there were no relevant studies concerning alternative therapy and oriental medication. Our case report is focused on treatment through these methods.

• Korean Journal of Environmental Biology
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• v.37 no.4
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• pp.474-482
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• 2019

Disease monitoring in wild aquatic animals is necessary to obtain information about disease occurrence, disease agents, and the transmission of diseases between wild and cultured species. In this study, we monitored viral diseases in wild marine fish and crustacea caught by trawl in Korea in April and October 2018. We monitored the viral diseases in 977 fish from 39 different species and 287 crustacea from 14 different species. In fish, we collected kidney and spleen to detect viral hemorrhagic septicemia virus (VHSV), red sea bream iridovirus (RSIV), marine birnavirus (MABV), hirame rhabdovirus (HRV), and lymphocystis disease virus (LCDV). In crustacea, we monitored white spot syndrome virus (WSSV), infectious hypodermal and hematopoietic necrosis virus (IHHNV), taura syndrome virus (TSV), infectious myonecrosis virus (IMNV), yellowhead disease virus (YHDV), and white tail disease virus (WTDV) using pleopods, pereiopods, gills, muscle, and hepatopancreases. Although none of the viral diseases tested in this study were detected in the samples, these results will help disease control between aquaculture species and wild aquatic animals.

• Journal of Veterinary Clinics
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• v.26 no.3
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• pp.212-219
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• 2009

Anticholinergics, which are commonly given as a pre-anesthetic medication to prevent adverse effects in canine anesthesia, can cause cardiac adverse effects. To determine the effects of atropine and glycopyrrolate on the balance of sympathetic nervous tone and parasympathetic nervous tone of the heart during ketamine anesthesia in beagle dogs, heart rate variability(HRV), duration of anesthesia and behavioral changes were evaluated. There were no significant temporal domain differences between atropine and glycopyrrolate. Concerning the frequency domain component, atropine and glycopyrrolate effects were significantly lower(P<0.05) than the control saline-treated group. However, the root mean square of the interval differences between consecutive R peaks(RMSSD) and the standard deviation of Poincare plot perpendicular to the line-of-identity(SD1) in atropine were significantly decreased(P<0.05) from the baseline value, and the low frequency/high frequency ratio(LF:HF ratio) in glycopyrrolate was significantly increased from baseline value(P<0.05). The change of SD1 agreed with that of the high frequency(HF) in the frequency domain component and also with those of respiratory rate and $SpO_2-R$. Our results prove that glycopyrrolate is more suitable as a pre-anesthetic anticholinergic in ketamine anesthesia of dogs with respect to safety and duration of action.

• Journal of Korean Society of Forest Science
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• v.104 no.2
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• pp.277-284
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• 2015

This study aims to evaluate the impact of forest therapy on neuro-cognitive, psychosocial, and physiological aspect of adolescent internet addiction risk group. We have classified potential and high risk user group as internet addiction risk group according to the criteria of Korean Internet Addiction Proneness Scale(K Scale). Based on the results of k-scale from the adolescents in metropolitan area from May to July 2013, 25 people were selected as Internet addiction risk group. We have randomized 13 participants joining forest therapy camp and 12 participants not joining one, and analyzed the change of the two groups with Continuous Performance, Kimberly S. Young, Connor-Davidson Resilience, Relationship Change Scale, heart rate variability and cortisol. Statistically significant changes were observedd in neuro-cognitive, psychosocial, and physiological variables, Through this study, we can consider that the therapy healing may relieve the level of internet addiction and can be an alternative to control emotional stability and impulsive behavior.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1999.11a
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• pp.233-237
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• 1999

Aromatherapy는 향을 이용하여 생리적 및 심리적 효과를 나타내는 치료법이다. 향의 종류에 따라 여러 효과들이 나타나고 있는데 본 연구에서는 이완 유도향 제품을 개발하기 위해 자율신경계로부터의 신호인 Galvanic skin resistance(GSR), 피부온도, 심박수 등과 뇌파에서의 변화를 측정하여 이완의 정도를 측정하고자 하였다. 실험방법은 4 종류의 aromatherapy용으로 조제된 복합향(#2033, #2026, #11, #13)을 이용하고 피검자는 후각기능이 정상이며 물리적 및 심리적 stress가 없고, 음주, 담배를 3일전까지 경험이 없는 군을 택하였다. 향을 주는 시간은 1분으로 하였으며 순서에 의한 효과를 없애기 위해 4 종류를 random order에 의해 실시하였다. 대조군으로는 증류수를 이용하여 실험 전, 실험 중, 실험 후에서 각각 측정하였으며 또한 각성효과가 좋은 jasmine과 이완 효과를 보이는 lavender를 같은 protocol로 시행하여 이완의 효과를 비교하였다. 뇌파는 FFT분석에 따라 각 주파수 영역 즉 beta, alpha, theta, delta로 나누어 분석하였다. Jasmine과 lavender의 이완 효과에서는 GSR의 변화와 HRV의 변화를 보고한 바 있다(백,1998). 또한 심리불안 효과와 향 이미지 검사를 동시에 시행하여 주관적지표로 삼았다. 실험 결과에서는 이러한 4 종류의 향은 모두 GSR의 현저한 감소 효과를 보였으며, 심박수와 피부온도의 감소경향을 나타내었다. 자율신경계 반응에 따라 4 종류 향의 이완 효과의 순서를 결정할 수 있었다. 주관적 검사와의 상관관계도 잘 나타났으며 이미지는 이완 정도와 섬세하다 항목이 잘 반영되었다. 뇌파의 변화에서는 의미 있는 변화는 보이지 않았다. 결론적으로 relaxation 효과는 GSR를 비롯한 자율신경계지표에서 잘 반영되었다.^2$=.792가 되었다. 설명되는 누적분산값은 67.18%였다.주관적 평가의 결과와 객관적 평가 결과를 이용해 마직물의 태를 평가하는 산출식을 제시하였다. 태 평가치의 경우 16가지 특성치를 모두 넣는 방법과 stepwise 방법, 또 Kawabatark 사용한 순차적 군 회귀법의 세가지 방법의 회귀식 중 16가지 특성치를 모두 넣는 방법의 결정계수가 가장 높았다.tosterone농도는 107.7$\pm$12.0 pmol／l이었고, 남성의 타액내 농도는 274.2$\pm$22.1 pmol／l이었다. 이상의 결과로 보아 본 연구에서 정립된 EIA 방법은 RIA를 대신하여 소규모의 실험실에서도 활용할 수 있을 것으로 사려된다.또한 상실기 이후 배아에서 합성되며, 발생시기에 따라 그 영향이 다르고 팽창과 부화에 관여하는 것으로 사료된다. 더욱이, 조선의 ${\ulcorner}$구성교육${\lrcorner}$이 조선총독부의 관리하에서 실행되었다는 것을, 당시의 사범학교를 중심으로 한 교육조직을 기술한 문헌에 의해 규명시켰다.nd of letter design which represents -natural objects and was popular at the time of Yukjo Dynasty, and there are some documents of that period left both in Japan and Korea. "Hyojedo" in Korea is supposed to have been influenced by the letter design. Asite- is also considered to have been "Japanese Letter Jobcheso." Therefore, the purpose of this study is to look in

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.6
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• pp.4021-4030
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• 2015

Pulse wave is the physiological responses through the autonomic nervous system such as ECG. It is relatively convenient because it can measure the signal just by applying a sensor on a finger. So, it can be usefully employed in the field of U-Healthcare. The objects of this study are acquiring the PPG (Photoplethysmography) one of the way of measuring the pulse waves in non-invasive way using the CMOS image sensor on a smartphone camera, developing the portable system judging stressful or not, and confirming the applicability in the field of u-Healthcare. PPG was acquired by using image data from smartphone camera without separate sensors and analyzed. Also, with that image signal data, HRV (Heart Rate Variability) and stress index were offered users by just using smartphone without separate host equipment. In addition, the reliability and accuracy of acquired data were improved by developing additional hardware device. From these experiments, we can confirm that measuring heart rate through the PPG, and the stress index for analysis the stress degree using the image of a smartphone camera are possible. In this study, we used a smartphone camera, not commercialized product or standardized sensor, so it has low resolution than those of using commercialized external sensor. However, despite this disadvantage, it can be usefully employed as the u-Healthcare device because it can obtain the promising data by developing additional external device for improvement reliability of result and optimization algorithm.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.2
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• pp.104-111
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• 2011

Objectives: The paper of 2001, China Medicine junguiyak stomach sickness9) proposed by the stomach is associated with digestive function, using dialectical gisulpyo PMS group to assess the patient's stomach function was to evaluate the diagnostic features. Methods: October 1, 2010 to November 15, 2010 women of childbearing age against a total of 25 people have responded to the survey was a random survey, 23 patients except two who were against the PMS 10 and 13 who were classified non-PMS group. Results: 1. Age group and non-PMS PMS theses, menstrual period is there was no statistically significant difference between the history of both the pill and had no information available on careers. 2. When comparing the total score PMS score was higher than in non-PMS group. This is a non-PMS PMS patients than in patients stomach functions normally fall. 3. Digestive function of the type of group, less PMS GanGi-woolche, Ganwool-Bihu, Bihu-Damsub, Hanyul-Chakchab significant difference in the items were found. 4. Digestive function of the type of group, less PMS GanGi-woolche the most significant was the type of apologetics. Conclusions: GanGi-woolche type was the most significant mental stress and autonomic tone of the PMS group, the higher the patient was likely to be included. Previously associated with HRV in the GanGi-woolche in a study evaluating the autonomic nervous system can be said to have relevance.

• The Journal of Internal Korean Medicine
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• v.41 no.3
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• pp.467-477
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• 2020

Objectives: This study investigated the cutaneous electrogastrogram (EGG) and other clinical characteristics of dyspeptic patients who have been diagnosed with Stomach Qi Deficiency (SQD) using the Scale for Stomach Qi Deficiency (SSQD). Methods: This study reviewed the clinical records of 38 patients with dyspepsia who were evaluated with SSQD and EGG at the Department of Digestive Diseases of Kyung Hee University Korean Medicine Hospital in Seoul, Korea from November 1, 2019 to February 29, 2020. We evaluated the EGG and other clinical characteristics of the SQD patients to determine if there was an association between the SSQD scores and the EGG. Results: In terms of the EGG, the SQD patients showed no significant increase in the percentage of normal slow wave after a meal and a slightly decreased power ratio at Channel 1 and Channel 2. We also found an association between the SSQD scores and the EGG parameters at Channel 1 and Channel 3. The average Ryodoraku score of the patients was 33.00±14.90 (μA). In the Heart Rate Variability (HRV) test, the average Total Power (TP) and Low Frequency/High Frequency (LF/HF)) ratio was 1356.60±13 6.41(ms²) and 1.68±2.25, respectively. Conclusions: The results of this study suggest that clinicians can use Electrogastrography to enhance accuracy when diagnosing the SQD pattern.