• YAKHAK HOEJI
• /
• v.40 no.3
• /
• pp.347-350
• /
• 1996

The post-antibiotic effect (PAE), which is defined as the period of time lag that the target organisms resume normal growth rate after complete removal of the antibiotics, of LB 20304 and ciprofloxacin was evaluated against Staphylococcus aureus 6538p and Escherichia coli 3190Y, respectively. The PAE was estimated by adding each antibiotic to a log phase of growth and incubating at $37^{\circ}$C for 1 h.Antibiotic was removed by centrifugation, and total viable cell counts were determined hourly for a further 10 h. The PAEs of LB20304 against S. aureus at concentrations of $1{\times}MIC\;and\;2{\mu}g/ml$ were 10 min and 93min, respectively. LB20304 showed a comparable PAE to ciprofloxacin. Against E. coli, the PAE of LB20304 was also similar to that of ciprofloxacin at concentration of $4{\times}MIC$ but it was much longer than that of ciprofloxacin at concentration of 2${\mu}g/ml$. LB20304 showed higher lethality than ciprofloxacin against both S. aureus and E. coli strains.

• Journal of Environmental Science International
• /
• v.29 no.1
• /
• pp.109-117
• /
• 2020

Asthmatics are more susceptible to fine particulate matters (PM_2.5), compared to the general population. It has been reported that indoor PM_2.5 is mainly generated by combustion of fossil fuels, meat or fish In particular, asthmatics are known to be more susceptible to indoor PM_2.5 because 65~95% of child or adult asthmatics stay inside the house. Thus, understanding the association between indoor activity patterns and variations in indoor PM_2.5 levels is important. The purpose of this study is to determine the distribution of hourly indoor PM_2.5 concentrations in asthmatics' homes, and to evaluate its association with pan-frying cooking activity patterns, the most common PM_2.5 emission related activity. From November 2017 to February 2018, real-time PM_2.5 concentrations were measured in the living room of each asthmatic's house (n = 35) for three weeks at 1 minute intervals. At the same time, self-reported daily activity patterns, hourly proportion (%) of cooking activities, were also recorded every hour over three weeks for each patient. In this study, we provided quantitative evidence that the distribution patterns of indoor hourly PM_2.5 concentrations were associated with indoor cooking activities, especially in the homes of adult asthmatics. In addition, we observed that PM_2.5 emitted by pan-frying could maintain even over up to 2 hour lagtime.

• Asian-Australasian Journal of Animal Sciences
• /
• v.25 no.11
• /
• pp.1568-1574
• /
• 2012

Three Holstein steers in the growing phase, each with a ruminal cannula, were used to test the hypothesis that the synchronization of the hourly rate of carbohydrate and nitrogen (N) released in the rumen would increase the amount of retained nitrogen for growth and thus improve the efficiency of microbial protein synthesis (EMPS). In Experiment 1, in situ degradability coefficients of carbohydrate and N in feeds including Korean rice wine residue (RWR) were determined. In Experiment 2, three total mixed ration (TMR) diets having different rates of carbohydrate and N release in the rumen were formulated using the in situ degradability of the feeds. All diets were made to contain similar contents of crude protein (CP) and neutral detergent fiber (NDF) but varied in their hourly pattern of nutrient release. The synchrony index of the three TMRs was 0.51 (LS), 0.77 (MS) and 0.95 (HS), respectively. The diets were fed at a restricted level (2% of the animal's body weight) in a $3{\times}3$ Latin-square design. Synchronizing the hourly supply of energy and N in the rumen did not significantly alter the digestibility of dry matter, organic matter, crude protein, NDF or acid detergent fiber (ADF) (p>0.05). The ruminal $NH_3$-N content of the LS group at three hours after feeding was significantly higher (p<0.05) than that of the other groups; however, the mean values of ruminal $NH_3$-N, pH and VFA concentration among the three groups were not significantly different (p>0.05). In addition, the purine derivative (PD) excretion in urine and microbial-N production (MN) among the three groups were not significantly different (p>0.05). In conclusion, synchronizing dietary energy and N supply to the rumen did not have a major effect on nutrient digestion or microbial protein synthesis (MPS) in Holstein steers.

• KIPS Transactions on Software and Data Engineering
• /
• v.9 no.4
• /
• pp.129-136
• /
• 2020

PM2.5 which is a very tiny air particulate matter even smaller than PM10 has been issued in the environmental problem. Since PM2.5 can cause eye diseases or respiratory problems and infiltrate even deep blood vessels in the brain, it is important to predict PM2.5. However, it is difficult to predict PM2.5 because there is no clear explanation yet regarding the creation and the movement of PM2.5. Thus, prediction methods which not only predict PM2.5 accurately but also have the interpretability of the result are needed. To predict hourly PM2.5 of Seoul city, we propose a method using random forest with the adjusted bootstrap number from the time series ground data preprocessed on different sources. With this method, the prediction model can be trained uniformly on hourly information and the result has the interpretability. To evaluate the prediction performance, we conducted comparative experiments. As a result, the performance of the proposed method was superior against other models in all labels. Also, the proposed method showed the importance of the variables regarding the creation of PM2.5 and the effect of China.

• Journal of Chest Surgery
• /
• v.25 no.10
• /
• pp.1048-1054
• /
• 1992

With use of a simple, inexpensive and nonpharmacological program for blood conservation, 24 consecutive patients underwent elective or urgent coronary artery bypass grafting without need of homologous red cell transfusions and /or fresh frozen plasma transfusions in 16 patients[66.7%]. Left internal mammary artery graftings were done in 18 patients[75%], with supplemental saphenous vein grafts in all. Intraoperatively, autologous heparinized blood was removed before bypass and retransfused at the conclusion of ext-racorporeal circulation. The volume remaining in the oxygenator and tubing set was returned without cell processing or hemofiltration. Using the hard-shell cardiotomy reservoir from the oxygenator, autotransfusion of the shed mediastinal blood was continued hourly by the next early;norning. The mean postoperative mediastinal blood loss was 364$\pm$234ml, whereas 553$\pm$383ml was autotransfused. 4 patients [16.7%] received homologous blood and an additional 4 patients[16.7%] fresh frozen plasma. Thus, in total, 16 patients[66.7%] were not exposed to any homologous blood products during the hospital stay. At discharge, the mean hemoglobin concentration was 10.3$\pm$1.6g /dl. Postoperative complications were few and there was no hospital death.

• Proceedings of the KSR Conference
• /
• 2007.05a
• /
• pp.1913-1926
• /
• 2007

Number of highway lanes and level of service are based on the 30th, 60th or 100th highest hour volume of the target year. On the other hand, railroad design volume is generally expressed in average annual daily traffic (AADT). This procedure ignores attributes of railroad demand's concentration on peak days and hours. Actual data analysis represents railroad's peaking characteristics very similar to those of highways. Therefore it is necessary to set a procedure in selecting design volume for railroad planning. This study presents a concept and the calculating procedure for railroad design hourly volume to analyze effect of railroad investment.

• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
• /
• v.1 no.1
• /
• pp.11-17
• /
• 1997

The treatment performances of anaerobic-aerobic activated sludge process were investigated under various operation conditions. The treatment system proposed in this study gave a relatively stable performance against hourly change of the flow rate and showed a satisfactory removal efficiency of nitrogen and phosphorus compounds under experimental conditions. The average removal efficiency of total nitrogen gradually decreased as the influent total nitrogen concentration was increased. High C/N ratio of the wastewater was required for the complete removal of nitrogen. Glucose as a carbon source was more efficient than starch and the removal ability for all components become higher with the increase of the fraction of glucose.

• Journal of Environmental Science International
• /
• v.1 no.1
• /
• pp.11-17
• /
• 1992

The treatment performances of anaerobic-aerobic activated sludge Process were investigated under various operation conditions. The treatment system proposed in this study gave a relatively stable performance against hourly change of the flow rate and showed a satisfactory removal efficiency of nitrogen and phosphorus compounds under experimental conditions. The average removal efficiency of total nitrogen gradually decreased as the influent total nitrogen concentration was increased. High C/N ratio of the wastewater was required for the complete removal of nitrogen. Glucose as a carbon source was more efficient than starch and the removal ability for all components become hither with the increase of the fraction of glucose.

• Journal of Korean Society for Atmospheric Environment
• /
• v.33 no.3
• /
• pp.251-264
• /
• 2017

Recently, Jeollabuk-do has been reported as a province where the $PM_{10}$concentration is one of the highest levels in South Korea. To explore the characteristics and origins of the $PM_{10}$in Jeollabuk-do, we present one of the first long-term datasets including a statistical analysis of $PM_{10}$concentrations obtained from six cities in the province from 2010 to 2015. During the entire periods, the mean hourly $PM_{10}$concentration was $49.3{\mu}g/m^3$, which correspond to the annual ambient air quality standards for $PM_{10}$in South Korea, and the annual $PM_{10}$concentration of each city showed a similarity in year-to-year variations. In the monthly variation of $PM_{10}$, the $PM_{10}$concentrations showed a maximum value in May that was one of the top levels among the provinces of Korea while the concentrations were dramatically decreased in August showing one of the lowest levels among the provinces in Korea. For the diurnal variation of $PM_{10}$, the $PM_{10}$concentration was enhanced during the rush hours together with gaseous species of $NO_2$, and CO. When the high concentrations of $PM_{10}$were observed (the highest 10% of the $PM_{10}$mass contribution), temperature and relative humidity were low. Using HYSPLIT backward trajectories and cluster analysis for the high $PM_{10}$concentrations, we found that the pollution plumes were transported mainly from China.

• Journal of Environmental Science International
• /
• v.28 no.1
• /
• pp.107-123
• /
• 2019

The aerosol chemical components in $PM_{2.5}$ in several regions (Seoul, Busan, Daejeon, and Jeju Island) were investigated with regard to their concentration characteristics and optical properties. The optical properties of the various aerosol components (e.g., water-soluble, insoluble, Black Carbon (BC), and sea-salt) were estimated using hourly and daily aerosol sampling data from the study area via a modeling approach. Overall, the water-soluble component was predominant over all other components in terms of concentration and impact on optical properties (except for the absorption coefficient of BC). The annual mean concentration and Aerosol Optical Ddepth (AOD) of the water-soluble component were highest in Seoul (at the Gwangjin site) ($26{\mu}g/m^3$ and 0.29 in 2013, respectively). Further, despite relatively moderate BC concentrations, the annual mean absorption coefficient of BC ($21.7Mm^{-1}$) was highest in Busan (at the Yeonsan site) in 2013, due to the strong light absorbing ability of BC. In addition, high AODs for the water-soluble component were observed most frequently in spring and/or winter at most of the study sites, while low values were noted in summer and/or early fall. The diurnal variation in the AOD of each component in Seoul (at the Gwangjin site) was slightly high in the morning and low in the afternoon during the study period; however, such distinctions were not apparent in Jeju Island (at the Aweol site), except for a slightly high AOD of the water-soluble component in the morning (08:00 LST). The monthly and diurnal differences in the AOD values for each component could be attributed to the differences in their mass concentrations and Relative Humidities (RH). In a sensitivity test, the AODs estimated under RH conditions of 80 and 90% were factors of 1.2 and 1.7 higher, respectively, than the values estimated using the observed RH.