• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.147.1-147.1
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• 2003

As an attempt to search for bioactive natural products exerting antiinflammatory activity, we have evaluated the anti-inflammatory and antinociceptive activities of the methanol extract from the Fomes fomentarius (MEFF). MEFF (50, 100 mg/kg/day, p.o.) significantly reduced an acute paw edema induced by carrageenan in rats. When analgesic activity was measured by acetic acid-induced writhing test and hot plate test, MEFF showed a dose-dependent inhibition in animal models. In addition, MEFF potently inhibited the LPS-induced production of NO, $PGE_2$ and TNF-$\alpha$production of macrophages. (omitted)

• 한국지역사회생활과학회지
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• 제27권2호
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• pp.295-304
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• 2016

This study was conducted to evaluate and compare the waterproofness and water vapor transport properties of 30 waterproof and breathable textiles in the market. MVTR upright cup test with water, MVTR inverted cup test with potassium acetate, and sweating hot plate test method were used for measuring the breathability of fabric samples. The waterproofness of all fabric samples and evaporative resistance of garment ensembles made with 5 selected waterproof and breathable textiles out of 30 samples were tested. The results of this study were as follows. The base fabrics of the most samples were basic weave structure with either polyester or nylon fiber. The waterproofness was over $5000mmH_2O$ for all the samples except densely woven fabrics. The evaporative resistance of garments that were made out of 5 fabric samples with a range of low to high breathability ranged $39.9{\sim}56.7m^2{\cdot}P{\cdot}W^{-1}$. The data of the water vapor transport properties of fabric samples varied with different test methods. Overall the bicomponent film fabrics showed better breathability and less standard deviation regardless of test methods. It is expected the breathability data without the information of test conditions used for marketing would confuse the consumers and the apparel manufacturers.

• 동의생리병리학회지
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• 제26권4호
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• pp.462-468
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• 2012

The present study was conducted with the object of examining how ST36 and LR3 electro acupuncture affects the injured side and the intact side in rats with sciatic nerve injury. For this study, we divided rats into a control group that were injured but not treated, experimental group I that were injured and had electro acupuncture on the intact side, experimental group II that were injured and had electro-acupuncture on the injured side, and experimental group III that were injured and had electro-acupuncture on both the intact side and the injured side, and performed behavioral and immunohistochemical tests. The results of this study are as follows. In the results of hot plate test, on Day 1 of experiment, experimental group I did not show a statistically significant difference but experimental group II and III showed a statistically significant difference, and on Day 2 and 3, all of experimental group I, II and III showed a statistically significant difference. In the results of SFI test, on Day 7 of experiment, experimental group I did not show a statistically significant difference but experimental group II and III showed a statistically significant difference, and on Day 14 and 21, all of experimental group I, II and III showed a statistically significant difference. In the results of immunohistochemical test, the expression of c-fos decreased gradually on Day 1, 2 and 3 in all the experimental groups, and the decrease was larger in the experimental groups that had electro-acupuncture than in the control group. In the results of immunohistochemical test, the expression of BDNF increased gradually on Day 7, 14 and 21 in all the experimental groups, and the expression was higher in the experimental groups than in the control group. Summing up the results, ST36 and LR3 electro acupuncture was effective when it was applied to the injured side and to both sides after sciatic nerve injury, but it was also effective in pain relief and nerve regeneration when it was applied to the intact side.

• Natural Product Sciences
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• 제19권4호
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• pp.311-315
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• 2013

Ribes fasciculatum (Saxifragaceae) has been widely used as a traditional medicine for the treatment of cough, antidote, cold, lacquer poison, and sore throat. In the present study, we evaluated the anti-nociceptive effects of ethyl acetate fraction of Ribes fasciculatum (ERF) in mice. Test results of tail-immersion test and hot plate test revealed that the ERF had strong anti-nociceptive activities on thermal nociception in a dose dependent manner, indicating ERF's anti-nociception on the central pain. Moreover, the acetic acid-induced chemical nociception was also significantly reduced by ERF treatment. This result shows that ERF may also work on the peripheral pain. We further performed formalin test to confirm ERF's anti-nociceptive properties and found that pain responses were significantly decreased by ERF treatment. Interestingly, in the combination test with naloxone, the analgesic activity of ERF was not changed, indicating that the opioid receptor was not involved in the ERF-mediated anti-nociception. These results indicate that ERF might be possibly used as a painkiller for the treatment of nociceptive pains.

• 대한기계학회논문집B
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• 제27권9호
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• pp.1299-1308
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• 2003

This paper is studied to investigate the effect of slits and swirl vanes on the development of turbulent flow fields in gun-type gas burner with a cone type baffle plate because this gas burner is generally composed of eight slits and swirl vanes. All of turbulent characteristics including mean velocities were measured in the horizontal plane and cross section by using X-type hot-wire probe from hot-wire anemometer system. This experiment is carried out at flow rate 450 l/min in the test section of subsonic wind tunnel. Slits cause the fast jets, and then they have the characteristic that the flow is not adequately spread to radial direction and has long flow length and very small flow velocity distribution in the central part. On the contrary, swirl vanes does not have long enough for adequate flow length to downstream because the rotational flow diffuses remarkably to radial direction. However, the suitable arrangement between slits and swirl vanes causes effective flow width and flow length, and then it promotes fast flow mixing over the entire region including central part to increase turbulence more largely and effectively. Therefore, it is thought as a very desirable design method in gun-type gas burner to locate slits on the outside of swirl vanes.

• Journal of the Korean Wood Science and Technology
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• 제42권3호
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• pp.258-265
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• 2014

목구조물 접합부에 기존 드리프트핀(Drift pin)을 대체하고자 단판이나 합판을 유리섬유강화플라스틱(GFRP: Glass fiber reinforced plastic)과 복합 적층시킨 GFRP보강적층목재핀을 제작하였다. 더불어 GFRP보강적층목재핀을 사용하여 집성재 접합부의 인장형 전단내력 시험을 실시하였다. GFRP 배열에 따른 보강적층목재핀의 휨강도 시험결과 GFRP를 각층에 1장씩 삽입한 시험편(Type-A)이 가장 양호한 성능을 발휘하였다. 또한 압체압력 $1.96N/mm^2$, 온도 $150^{\circ}C$에서 한 시간 열압하여 고밀화한 시험편이 고밀화하지 않은 시험편과 비교하여 휨강도 성능이 1.57배 향상됨을 확인하였으며, 하중방향에 따라 Edgewise가 Flatwise보다 3.51배 높은 성능을 발휘하였다. 시험을 통해 가장 양호한 성능을 보인 Type-A 보강적층목재핀을 이용하여 전단내력 시험을 실시하였다. 접합구의 종류와 접합판의 종류를 달리하여 시험한 결과 드리프트핀과 강판을 적용한 시험체(Type-DS)와 비교하여 GFRP보강적층목재핀과 GFRP보강목재적층판을 적용한 시험체(Type-WL)가 1.12배 높은 전단내력이 측정되었으며 최대하중 이후에도 매우 양호한 인성이 관찰되었다.

• 대한기계학회논문집B
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• 제34권2호
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• pp.203-212
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• 2010

수분류 스프레이 냉각은 많은 산업적인 응용분야에 넓게 사용되고 있다. 본 연구는 수분류 스프레이가 표면거칠기가 주어진 $900^{\circ}C$ 고온강판의 표면에 충돌하는 경우, 열유속 및 열전달계수의 정량적인 측정을 통해 표면거칠기가 수분류 스프레이 냉각에 미치는 영향을 고찰하였다. 이 때의 국소 열유속은 시편, 카트리지히터, 열전대의 조합으로 고안된 고유의 열유속게이지를 제작하여 엄밀하게 측정되었다. 평균 표면거칠기 높이를 기준으로 40, 60, $80{\mu}M$의 3 가지 표면과 매끈한 표면에 대한 수분류 스프레이 냉각 의 열전달 현상이 비교 및 평가되었다. 표면거칠기가 주어진 표면에서의 돌출물은 얇은 열 경계층두께를 통과할 수 있기 때문에 표면거칠기가 주어진 경우에 열전달은 뚜렷하게 증가하였고, 표면거칠기의 의한 열전달 향상 기구는 서로 다른 비등영역에 대해 구분하여 조사되었다.

• 대한기계학회논문집B
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• 제27권4호
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• pp.466-475
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• 2003

The gun-type gas burner adopted in this study is generally composed of eight slits and swirl vanes. Thus, this paper is studied to investigate the effect of slits and swirl vanes on the turbulent flow fields in the horizontal plane of gas swirl burner with a cone type baffle plate measured by using X-probe from hot-wire anemometer system. This experiment is carried out at flow rate 450 $\ell$/min in the test section of subsonic wind tunnel. The axial mean velocity component in the case of burner model with only swirl vanes shows the characteristic that spreads more remarkably toward the radial direction than axial one, it does, however, directly opposite tendency in the case of burner model with only slits. Consequently. both slits and swirl vanes composing of gun-type gas burner play an important role in decrease of the speed near slits and increase of the flow speed in the central part of a burner because the biggest speed spurted from slits encircles rotational flow by swirl vanes and it drives main flow toward the axial direction. Moreover, the turbulent intensities and turbulent kinetic energy of gun-type gas burner are distributed with a fairly bigger size within X/R<0.6410 than burner models which have only slits or swirl vanes because the rotational flow by swirl vanes and the fast jet flow by slits increase flow mixing, diffusion, and mean velocity gradient effectively.

• Tribology and Lubricants
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• 제38권3호
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• pp.93-100
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• 2022

Micro-light emitting diode (micro-LED) displays offer numerous advantages such as high brightness, fast response, and low power consumption. Hence, they are spotlighted as the next-generation display. However, defective LEDs may be created due to non-uniform contact loads or LED alignment errors. Therefore, a repair process involving the replacement of defective LEDs with favorable ones is necessitated. The general repair process involves the removal of defective micro-LEDs, interconnection material transfer, as well as new micro-LED transfer and bonding. However, micro-LEDs are difficult to repair since their size decreases to a few tens of micron in width and less than 10 ㎛ in thickness. The conventional nozzle-type dispenser for fluxes and the conventional vacuum chuck for LEDs are not applicable to the micro-LED repair process. In this study, transfer conditions are determined using a micro stamp for repairing micro-LEDs. Results show that the aging time should be set to within 60 min, based on measuring the aging time of the flux. Additionally, the micro-LEDs are subjected to a compression test, and the result shows that they should be transferred under 18.4 MPa. Finally, the I-V curves of micro-LEDs processed by the laser and hot plate reflows are measured to compare the electrical properties of the micro-LEDs based on the reflow methods. It was confirmed that the micro-LEDs processed by the laser reflow show similar electrical performance with that processed by the hot plate reflow. The results can provide guidance for the repair of micro-LEDs using micro stamps.

• 약학회지
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• 제51권6호
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• pp.508-516
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• 2007

Thymus magnus is an endemic (Ulleung Island) species in Korea. This plant is used as diaphoretics and carminatives in traditional medicine. In the literature, few scientific assays were realized on this species, such as antibiotic (Streptococcus pneumoniae, Staphylococcus aureus, Salmonella enteritidis, and S. typhimurium) and antifungal activities. In order to clarify whether essential oil of T. magnus have pharmacological effects, anti-inflammatory, sedative, anti-depressant, analgesic, and sleep-prolonged effects were investigated using animal models. From this study, the following conclusions were attained; 1) Essential oil of T. magnus did not show any acute toxicity on mice when orally administered at the dose of 2-3 g/kg body weight. 2) Essential oil of T. magnus possessed strong anti-inflammatory activity, similar to that of a positive control prednisolone. 3) Essential oil of T. magnus had excellent analgesic activity, comparable to that of aspirin. 4) The essential oil of T. magnus possessed strong sleep-prolonged effect on pentobarbital induced-sleep test in mice model. 5) In the hot plate test, the essential oil of T. magnus had moderate effect. 6) And the essential oil of T. magnus had no significant effects in forced-swimming test and open-field test.