• 제목/요약/키워드: Hospital medicine

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Bacteriologic Analysis of Expectorated Sputum in Patient with Bronchiectasis (기관지확장증 환자의 객담 균주 분석: 울산지역의 일개 대학병원 보고)

  • Seo, Kwang Won;Hwang, Se Jin;Sung, Shi Jung;Kim, Se Jin;Do, Gi Won;Hur, Seong Jae;Lim, Kyung Hun;Hong, Soon Hyung;Kim, Dong Min;Jeon, Jae Bum;Jegal, Yangjin;Choi, Seung Won;Kwon, Woon Jung;Jeong, Joseph;Ahn, Jong Joon
    • Tuberculosis and Respiratory Diseases
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    • v.67 no.6
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    • pp.517-527
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    • 2009
  • Background: Bronchiectasis (BE) remains a rare respiratory disease in Korea. This retrospective study was done to investigate the potential pathogenic microorganisms (PPMs) that cause in patients with BE, through the use of sputum specimens. Methods: One hundred eleven adult patients, who had undergone chest computed tomography (CT), sputum gram stain/culture, and BE detected by chest CT, were included in this study. Sputum adequacy was determined by using Murray-Washington classification. Results: The mean (${\pm}$SD) age of patients was 60.9 (${\pm}$14.0). The number of PPMs was 167 (67%) in the total 248 isolated organisms. The most frequent PPMs were P. aeruginosa (23.4%), K. pneumoniae (10.5%), and S. aureus (8.4%). The proportion of adequate sputum (AS) was 25.8% in the total sputum specimens. The patients with AS were 41 (37%) and the patients with inadequate sputum (IS) were 70 (63%). The proportion of P. aeruginosa was higher in AS compared to that of IS (44% vs. 19%, p=0.004). The BE score was also higher in P. aeruginosa (+) patients compared to that of P. aeruginosa (-) patients (10.8 vs. 7.6, p=0.001). Conclusion: Although the proportion of AS in the total sputum was low, PPMs were isolated in most patients with BE. It is likely that P. aeruginosa was isolated in AS and AS patients had higher BE scores.

A Case Report of Korean Medicine Treatment of a Lung Cancer Patient with Chemotherapy-induced Peripheral Neuropathy (편평상피세포 폐암 환자의 항암화학요법에 의해 유발된 말초신경병증에 대한 한방치험 1례)

  • Kim, Kyun Ha;Kim, Min-hwa;Heo, Gi-yoon;Lee, Chan;Cho, Im-hak;Kang, Hee-kyung;Kim, So-yeon;Park, Seong-ha;Yun, Young-ju;Lee, In;Han, Chang-woo;Hong, Jin-woo;Kwon, Jung-nam;Choi, Jun-Yong
    • The Journal of Internal Korean Medicine
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    • v.42 no.6
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    • pp.1341-1348
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    • 2021
  • The purpose of this study is to report the effect of Korean medicine on a squamous cell lung cancer patient with chemotherapy induction peripheral neuropathy (CIPN). A 61-year old male patient, who had received 4 cycles of chemotherapy after lung surgery from squamous cell lung cancer, was treated with acupuncture and herbal medicines, including Uchasingi-hwan and Samchilchoongcho-capsule, to control CIPN and dyspnea on exertion. The degree of pain was assessed by a numeric rating scale (NRS). After receiving acupuncture and herbal medicines, the NRS score for CIPN symptoms was reduced from 4 to 1 and the NRS score for dyspnea on exertion decreased from 3 to less than 1. Korean medicine could therefore be useful in reducing peripheral neuropathy occurring after chemotherapy and dyspnea after lobectomy.

Effect of Korean Medicine Treatment Combined with Conventional Medicine in Patients Diagnosed with Plantar Fasciitis

  • Jeong, Seong Heon;Jang, Kwon-Jun;Moon, Hyang-Ran;Jo, On You;Lee, Ji Yoon;Yang, Jung Min;Choi, Saerom;Yoon, Min Ji;Shin, Gwangsoon;Kim, Hyo-Rim
    • Journal of Acupuncture Research
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    • v.39 no.2
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    • pp.145-149
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    • 2022
  • This study examined the effectiveness of Korean-Western cooperative treatment for patients with plantar fasciitis. Fifty patients received Korean medicine treatments (acupuncture, pharmacopuncture, herbal medicine) and Western medicine treatments (polydeoxyribonucleotide, and extracorporeal shock wave therapy). Evaluation methods used were comparison before and after ultrasound (P9), and numeric rating scale scores. Results revealed a significant improvement in the level of pain and evaluation of improvement using ultrasound. Moreover, it was suggested that Korean-Western cooperative medicine treatment may be effective for the treatment of plantar fasciitis.

Bilateral Triple Negative Invasive Ductal Breast Carcinoma in a BRCA1 Mutation Carrier with Discrepant Pathologic Response to Neoadjuvant Chemotherapy (BRCA 유전자 변형 환자의 양측 삼중음성 유방암의 선행화학요법에 대한 상이한 반응)

A Case of Peritoneal Tuberculosis Developed after Infliximab Therapy for Refractory RA

  • Min, Ji-Yeon;Bang, So-Young;Min, Seung-Yeon;Lee, Dae-Sung;Kim, Bo-Sang;Kim, Jeong-Eun;Lee, Eun-Sung;Pyo, Ju-Yeon;Sohn, Jang-Won;Kim, Tae-Hyung;Lee, Hye-Soon
    • Tuberculosis and Respiratory Diseases
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    • v.73 no.4
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    • pp.234-238
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    • 2012
  • Recently, interferon gamma releasing assay has been recommended to compensate the tuberculin skin test (TST) for screening for latent tuberculosis infection (LTBI). Although it improved the detection of LTBI before treatment with tumor necrosis factor blocker, its application to immune suppressed patients is limited. We report a case of peritoneal tuberculosis (TB) developed in a patient who tested positive for TST and QuantiFERON-TB Gold (QFT-G) before infliximab therapy, to emphasize the importance of monitoring during treatment. A 52-year-old woman presented with abdominal distension. She had been diagnosed with seropositive rheumatoid arthritis six years ago. She had started taking infliximab six months ago. All screening tests for TB were performed and the results of all were negative. At admission, the results of repeated TST and QFT-G tests were positive. Histopathological examination confirmed peritoneal TB. The patient started anti-TB therapy and the symptoms were relieved.

A Review of Diagnostic Methods on Neurologic Symptoms by Non-organic Causes: A Case of a Patient (비기질적 원인에 의한 신경학적 증상 감별법에 대한 고찰: 사례를 중심으로)

  • Cho, Min Kyoung;Lim, Jung Hwa;Park, Seung Chan;Kim, Do Hyung;Kim, So Yeon;Choi, Jun Yong;Han, Chang Woo;Park, Seong Ha;Hong, Jin Woo;Kwon, Jung Nam;Lee, In
    • Journal of Oriental Neuropsychiatry
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    • v.25 no.1
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    • pp.63-72
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    • 2014
  • Objectives: The objective of this study is to review the diagnostic methods of neurologic symptoms by non-organic causes. Methods: We experienced a case of a motor and sensory disturbance patient without abnormal findings in the diagnostic tests. Using this process, we became aware that it is important to remember some of the methods when treating patients who are suspicious of neurologic symptoms by non-organic causes. Results: First, we should perform a variety of diagnostic tests to exclude the organic causes. Second, we should persistently observe a consistency of the patient's symptoms and attitude. Finally, we should perform a neurological examination in order to acquire the objective physical findings. Conclusions: Because there are limitations in the methods above, we have to be aware of making a mistake regarding the disability by organic causes as that by non-organic causes.

Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome

  • Lee, Seung Hyun;Kim, Jae Hyung;Park, Sejin;Won, Chang Youn;Lee, Joo-Hyun;Yi, Seong Yoon;Park, Hye Kyeong;Chang, Sun Hee;Jung, Hoon;Lee, Sung-Soon;Koo, Hyeon-Kyoung
    • Tuberculosis and Respiratory Diseases
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    • v.79 no.4
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    • pp.302-306
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    • 2016
  • Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS.

A Multicenter Study to Identify the Respiratory Pathogens Associated with Exacerbation of Chronic Obstructive Pulmonary Disease in Korea

  • Lee, Hyun Woo;Sim, Yun Su;Jung, Ji Ye;Seo, Hyewon;Park, Jeong-Woong;Min, Kyung Hoon;Lee, Jae Ha;Kim, Byung-Keun;Lee, Myung Goo;Oh, Yeon-Mok;Ra, Seung Won;Kim, Tae-Hyung;Hwang, Yong Il;Rhee, Chin Kook;Joo, Hyonsoo;Lee, Eung Gu;Lee, Jin Hwa;Park, Hye Yun;Kim, Woo Jin;Um, Soo-Jung;Choi, Joon Young;Lee, Chang-Hoon;An, Tai Joon;Park, Yeonhee;Yoon, Young-Soon;Park, Joo Hun;Yoo, Kwang Ha;Kim, Deog Kyeom
    • Tuberculosis and Respiratory Diseases
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    • v.85 no.1
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    • pp.37-46
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    • 2022
  • Background: Although respiratory tract infection is one of the most important factors triggering acute exacerbation of chronic obstructive pulmonary disease (AE-COPD), limited data are available to suggest an epidemiologic pattern of microbiology in South Korea. Methods: A multicenter observational study was conducted between January 2015 and December 2018 across 28 hospitals in South Korea. Adult patients with moderate-to-severe acute exacerbations of COPD were eligible to participate in the present study. The participants underwent all conventional tests to identify etiology of microbial pathogenesis. The primary outcome was the percentage of different microbiological pathogens causing AE-COPD. A comparative microbiological analysis of the patients with overlapping asthma-COPD (ACO) and pure COPD was performed. Results: We included 1,186 patients with AE-COPD. Patients with pure COPD constituted 87.9% and those with ACO accounted for 12.1%. Nearly half of the patients used an inhaled corticosteroid-containing regimen and one-fifth used systemic corticosteroids. Respiratory pathogens were found in 55.3% of all such patients. Bacteria and viruses were detected in 33% and 33.2%, respectively. Bacterial and viral coinfections were found in 10.9%. The most frequently detected bacteria were Pseudomonas aeruginosa (9.8%), and the most frequently detected virus was influenza A (10.4%). Multiple bacterial infections were more likely to appear in ACO than in pure COPD (8.3% vs. 3.6%, p=0.016). Conclusion: Distinct microbiological patterns were identified in patients with moderate-to-severe AE-COPD in South Korea. These findings may improve evidence-based management of patients with AE-COPD and represent the basis for further studies investigating infectious pathogens in patients with COPD.