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http://dx.doi.org/10.4046/trd.2009.67.6.517

Bacteriologic Analysis of Expectorated Sputum in Patient with Bronchiectasis  

Seo, Kwang Won (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Hwang, Se Jin (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Sung, Shi Jung (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Kim, Se Jin (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Do, Gi Won (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Hur, Seong Jae (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Lim, Kyung Hun (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Hong, Soon Hyung (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Kim, Dong Min (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Jeon, Jae Bum (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Jegal, Yangjin (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Choi, Seung Won (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Kwon, Woon Jung (Department of Diagnostic Radiology, Ulsan University Hospital, University of Ulsan College of Medicine)
Jeong, Joseph (Department of Laboratory Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Ahn, Jong Joon (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.67, no.6, 2009 , pp. 517-527 More about this Journal
Abstract
Background: Bronchiectasis (BE) remains a rare respiratory disease in Korea. This retrospective study was done to investigate the potential pathogenic microorganisms (PPMs) that cause in patients with BE, through the use of sputum specimens. Methods: One hundred eleven adult patients, who had undergone chest computed tomography (CT), sputum gram stain/culture, and BE detected by chest CT, were included in this study. Sputum adequacy was determined by using Murray-Washington classification. Results: The mean (${\pm}$SD) age of patients was 60.9 (${\pm}$14.0). The number of PPMs was 167 (67%) in the total 248 isolated organisms. The most frequent PPMs were P. aeruginosa (23.4%), K. pneumoniae (10.5%), and S. aureus (8.4%). The proportion of adequate sputum (AS) was 25.8% in the total sputum specimens. The patients with AS were 41 (37%) and the patients with inadequate sputum (IS) were 70 (63%). The proportion of P. aeruginosa was higher in AS compared to that of IS (44% vs. 19%, p=0.004). The BE score was also higher in P. aeruginosa (+) patients compared to that of P. aeruginosa (-) patients (10.8 vs. 7.6, p=0.001). Conclusion: Although the proportion of AS in the total sputum was low, PPMs were isolated in most patients with BE. It is likely that P. aeruginosa was isolated in AS and AS patients had higher BE scores.
Keywords
Bronchiectasis; Sputum; Microbiology; Bacteriology;
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