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http://dx.doi.org/10.4046/trd.2016.79.4.302

Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome  

Lee, Seung Hyun (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Kim, Jae Hyung (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Park, Sejin (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Won, Chang Youn (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Lee, Joo-Hyun (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Yi, Seong Yoon (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Park, Hye Kyeong (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Chang, Sun Hee (Department of Pathology, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Jung, Hoon (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Lee, Sung-Soon (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Koo, Hyeon-Kyoung (Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.79, no.4, 2016 , pp. 302-306 More about this Journal
Abstract
Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS.
Keywords
Myelodysplastic Syndromes; Vasculitis, Leukocytoclastic, Cutaneous; Paraneoplastic Syndromes; Pneumonia;
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