• 한국식생활문화학회지
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• 제17권2호
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• pp.153-164
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• 2002

This study examined the consumers' awareness and information need toward the irradiated foods and environmental hormones. The data were collected from 350 adults living in Daegu and Busan by the self-administered questionnaire. Frequencies and chi-square tests were conducted by SPSS. The results of the survey were as follows: (1) consumers' awareness regarding the irradiated foods and environmental hormones were low, while consumers' concerns for them were high, (2) the orders of the information needs for the irradiated foods are safety of irradiated foods, dose permitted for food irradiation, benefits of irradiated foods, kinds of permitted irradiated foods, and legislations of food irradiation, and (3) the orders of the information needs for the environmental hormones are harmfulness of environmental hormones, standards for contamination by environmental hormones, materials releasing environmental hormones, methods to prevent environmental hormones, and kinds of environmental hormones.

• 분석과학
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• 제21권6호
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• pp.526-534
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• 2008

가축의 생산성 향상을 위해 투여될 수 있는 천연호르몬과 합성 호르몬제 등의 내분비계장애물질에 대하여 기존의 분석 방법을 개선 및 확립하고, 이를 토대로 국내에 유통 중인 육류 및 내장부위 중소간에 대해 호르몬 성분의 분포정도를 확인하였다. Estrogens ($17{\beta}$-estradiol, $17{\alpha}$-estradiol, estrone), androgens ($17{\beta}$-testosterone, $17{\alpha}$-testosterone), gestagens (progesterone)의 천연호르몬 6종과 합성호르몬 3종 DES, RALs (zeranol, taleranol)을 모니터링 대상 호르몬으로 GC-MS로 분석하였으며, 이로부터 호르몬의 background level을 측정하고, 상대적으로 호르몬제 등이 잔류될 수 있는 간 등의 장기에 대한 분포조사를 실시하였다. 전체 150건의 시료 중 합성 호르몬제는 검출되지 않았으며, 천연호르몬제는 내인성으로 존재하는 progesterone이 일반적인 농도 범위를 보였다.

• 한국직업건강간호학회지
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• 제28권4호
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• pp.285-292
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• 2019

Purpose: This study aimed to examine the factors associated with behavior that reduces exposure to environmental hormones among nursing students. Methods: Data were collected from 160 nursing students in D and B cities, using self-report questionnaires. Data were analyzed using SPSS 22.0, and the analyses included descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient test, and stepwise multiple regression. Results: Behavior that reduces exposure to environmental hormones differed significantly in terms of the participants' knowledge about environmental hormones. Behavior that reduces exposure to environmental hormones was negatively correlated with knowledge of environmental hormones, attitude towards pro-environmental behavior, and environmental self-efficacy; these factors were significant predictors of behavior that reduces exposure to environmental hormones, and accounted for 27.0% of the variance. Conclusion: Environmental self-efficacy was identified as the most significant factor affecting behavior that reduces exposure to environmental hormones in nursing students. Therefore, it is necessary to develop programs to improve pro-environmental behavior and environmental self-efficacy in nursing students.

• 대한의생명과학회지
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• 제11권3호
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• pp.253-258
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• 2005

Reactive oxygen species (ROS) and sex hormones affect the proliferation of cells and are believed to play important roles in tumorigenesis. However, little is known regarding how these two factors interact to affect cell proliferation. In this study, hepal-6 cells were treated with ROS and sex hormones (testosterone and steroidal) either separately or in combination. The sex hormones had no significant influence the cell proliferation up to a concentration of $1{\mu}M$. However, cell proliferation was inhibited when the cells were treated simultaneously with $H_2O_2$, which alone was found to promote cell proliferation at the concentrations of $15{\mu}M$. In conclusion, this study indicates that instead of promoting the cell proliferation, ROS interact with sex hormones to inhibit the Hepa 1-6 cell proliferation.

• 한국임상수의학회지
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• 제30권1호
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• pp.22-26
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• 2013

To monitor the reproductive patterns of endangered orangutan, Time-resolved fluorescence immuno assay (TR-FIA) were used to analyze metabolites of sex hormones in feces. Orangutan had long-term interbirth intervals (amenorrhea) during lactation period in which the secretion of sex hormones was repressed. The concentration of progesterone in the serum of pregnant orangutan was 30fold higher than that in non-pregnant orangutan. However, the concentration of hCG during pregnant period was different from the result of other primates. The present study suggested that age is not the important factor in determining the reproduction capability, because it is rather greatly influenced by the combination of various factors. Tracing metabolites of sex hormones in orangutan feces seems to be provide the effective solution for the infertility in orangutan. This study result shows the basic data in operating conservation project for endangered orangutan.

• Bulletin of the Korean Chemical Society
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• 제32권3호
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• pp.809-814
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• 2011

A method based on the TMS derivatives and acidic hydrolysis was developed for the simultaneous determination of free and conjugated steroidal hormones in surface water. A silylation of five natural and two synthetic steroidal hormones was achieved with N-methyl-N-(trimethylsilyl) trifluoroacetamide/$NH_4I$ (1000:3) under catalysis of dithioerythritol for 60 min at $80^{\circ}C$. TMS derivatives of the steroid hormones containing multifunctional groups offer a single derivative product under this condition. The accuracy of the analytes was in the range of 87 to 110% at a concentration of 20 and 50 ng/L with relative standard deviations of less than 10%. The method detection limit was in the range of 0.01 to 0.02 ng/L for surface water. Natural steroidal hormones were detected in a concentration range of 0 to 1.03 ng/L in free form and 0 to 14.6 ng/L in conjugated form, respectively. We found that most of the natural hormonal steroids exist in conjugate forms (43 to 100%) in river water.

• 과학기술학연구
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• 제14권1호
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• pp.87-116
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• 2014

이글은 불법적 호르몬 약물 소비행위라는 다소 이질적인 형태의 약물화(pharmaceuticalization) 현상에 주목한다. 운동선수들에게 아나볼릭스테로이드와 같은 호르몬 약물의 사용은 더 이상 생소한 일이 아니다. 거대한 근육을 획득하거나 힘을 증가시키기기 위해 운동선수들이 합성호르몬을 자신들만의 방식으로 사용하고 있다. 이러한 약물 사용 행위는 단순히 불법적인 것으로 볼 수 없다. 이들은 내분비계 전문의와 같은 의료전문가들과 대조되는 약물에 대한 지식을 형성하고, 합리적으로 약물을 소비한다. 의사들이 합성호르몬의 역할을 치료(treatment)에 한정지었다면, 약물 사용자들은 향상(enhancement)까지 확장시키고 있다. 합성호르몬의 새로운 역할에 가치가 부여되고 비공식적인 시장이 형성되고 있는 것이다. 이글은 생명정치와 생의료화의 비공식적인 현상으로 호르몬 약물 사용을 분석하고자 한다.

• Journal of Animal Science and Technology
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• 제65권1호
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• pp.16-31
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• 2023

Cultured meat is a potential sustainable food generated by the in vitro myogenesis of muscle satellite (stem) cells (MSCs). The self-renewal and differentiation properties of MSCs are of primary interest for cultured meat production. MSC proliferation and differentiation are influenced by a variety of growth factors such as insulin-like growth factors (IGF-1 and IGF-2), transforming growth factor beta (TGF-β), fibroblast growth factors (FGF-2 and FGF-21), platelet-derived growth factor (PDGF) and hepatocyte growth factor (HGF) and by hormones like insulin, testosterone, glucocorticoids, and thyroid hormones. In this review, we investigated the roles of growth factors and hormones during cultured meat production because these factors provide signals for MSC growth and structural stability. The aim of this article is to provide the important idea about different growth factors such as FGF (enhance the cell proliferation and differentiation), IGF-1 (increase the number of myoblasts), PDGF (myoblast proliferation), TGF-β1 (muscle repair) and hormones such as insulin (cell survival and growth), testosterone (muscle fiber size), dexamethasone (myoblast proliferation and differentiation), and thyroid hormones (amount and diameter of muscle fibers and determine the usual pattern of fiber distributions) as media components during myogenesis for cultured meat production.

• 한국환경보건학회지
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• 제38권3호
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• pp.195-203
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• 2012

Objectives: This paper aims to investigate the influence on stress hormones of job stress resulting from firefighting duties, as well as the degree of such influence. Methods: KOSS-26 and stress hormones such as norepinephrine (NE), epinephrine (EPI), adrenocorticotrophic hormone (ACTH), and cortisol were analyzed for 191 male firefighters from the western area of Incheon, the Incheon Industrial Complex, and Bucheon, Korea. Job stress and stress hormones were compared between a office working group and field-working group. Results: There was no significant difference in EPI and ACTH between the two groups. Change of stress hormones prior to engaging in typical duties, following typical duties, and immediately after field activities was examined. All the EPI, ACTH, and cortisol showed statistically significant changes with time, but not NE in the blood. In the field-working group, the cortisol levels in the blood of the firefighting and rescue groups showed notable differences depending on the time at which the measurements were taken. Conclusion: The differences in stress hormone levels depending on the type of duties of the firefighters were identified. Thus, interventions proper to job requirements is required in order to ease stress.

• 한국가축번식학회지
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• 제14권3호
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• pp.223-230
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• 1990

This experiment was carried out to investigate in vitro maturation rate of pig follicular oocytes cultured from 30 to 48hr in TCM 199 supplemented with gonadotropins(FSH, LH) and estradiol-17$\beta$ and in vitro fertilization with ejaculated sperm preincubated in BO medium containing 2mM caffein and development of IVF oocytes. The results obtained in this experiments were as follows ; 1. In addition of hormones, in vitro maturation rate of follicular oocyte increased gradually from 36hr and 74.47% at 48hr in addition of hormones, but there was no differences among in vitro maturation rates after 36hr of culture. 2. Penetration rate of pig oocytes matured in FSH＋LH＋E2 and FSH＋E2 was 71.8%, 71.0% and significantly increased by the addition of hormones. 3. Percentage of developed oocytes was 44.4% for oocytes matured in FSH＋LH＋E2-added medium and 48.7% for oocytes matured in FSH＋E2-added medium, respectively. 4. Two to 16 cells stage embryos were obtained only when pig oocytes matuerd in vitro in hormones-added medium and 72hr after IVF. 5. From present results, it is concluded that gonadotropins and estradiol17$\beta$ can enhance in vitro fertilization and subsequent development as well as in vitro maturation pig follicular oocytes.