• Journal of the Korean Applied Science and Technology
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• v.33 no.4
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• pp.667-675
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• 2016

Nanoemulsions are actively used in several applications for pharmaceutical, cosmetic and chemical industries. In this study, we propose the use of microfluidizer known as high pressure homogenizer to prepare lipid nanoemulsion as a potent cosmetic delivery carrier. The lipid nanoemulsions were prepared by O/W emulsion with hydrogenated lecithin and different type of oils. Effects of oil type on the stability of the lipid nanoemulsion were investigated with Dynamic Light Scattering (DLS) and Zeta-potential. Arbutin was used as model drug for transdermal administration through hairless mouse skin. Transdermal arbutin delivery using the lipid nanoemulsions was studied with HPLC method.

• Bulletin of the Korean Chemical Society
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• v.30 no.4
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• pp.821-824
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• 2009

In this study, a hydrogenated lecithin-containing nanoemulsion was prepared from hydrogenated lecithin and silicone oil. Tween-60 and liquid paraffin, widely known emulsifiers, were used as standard substances, and high shear was produced by utilizing a high shear homogenizer and microfluidizer. The properties of the nanoemulsion prepared with hydrogenated lecithin were evaluated by measuring interfacial tension, dynamic interfacial tension, droplet size, zeta-potential, friction force, skin surface hygrometery, and dermal safety. The interfacial tension of lecinol S10/silicone oil was lower than that of lecinol S10/liquid paraffin. The nanoemulsion prepared from hydrogenated lecithin shows lower zeta-potential, skin surface hygrometery, and friction force compared with a general emulsion. The silicone nanoemulsion prepared from hydrogenated lecithin showed a zero value in the patch test and thus exhibits high dermal safety.

• KSBB Journal
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• v.26 no.5
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• pp.381-385
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• 2011

Studies were made to improve the stability of astaxanthin which has application limitations caused by light and thermal stability problems in spite of its strong anti-oxidant property. Astaxanthin was extracted from Haematococcus pluvialis with supercritical carbon dioxide. Liposomal encapsulation of astaxanthin to improve the stability was made with high pressure homogenizer. The narrow size distribution was observed with astaxanthin liposomes. Tests on light and thermal stabilities resulted that the liposormal encapsulation improved the stability of astaxanthin for cosmeceutical purposes.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.2
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• pp.213-218
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• 2013

In this study, epoxy/mica composite was prepared by mixing with mechanical stirrer together with homogenizer, and the effect of amino-type silane coupling agent was also studied. To reduce the viscosity without any decrement of other properties, 1,4-Butanediol diglycidyl ether (1,4-BDGE) as an aliphatic epoxy reactive diluent was introduced to the epoxy/mica composite in order to use as vanish for high voltage motor and generator stator winding. It was confirmed by scanning electron microscopy (SEM) observation that interfacial characteristics between organic epoxy and inorganic mica was modified by coupling agent treatment so that glass transition temperature increased, and tensile strength and electrical breakdown strength increased. The properties were estimated by Weibull statistical analysis and the ac electrical breakdown strength was 20.2% modified by treating silane coupling agent.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2022.04a
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• pp.95-96
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• 2022

Carbon nanotubes has a positive effect on the mechanical properties, functionality, and durability of cement-based materials. In this study, carbon nanotube solutions mixed with two different types of superplasticizers were dispersed by high-pressure homogenizer, and used for preparation of cement paste. The 7and 28day compressive strength were evaluated.

• Journal of Ceramic Processing Research
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• v.13 no.spc1
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• pp.145-148
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• 2012

Spherical silica aerogel powders were fabricated via an emulsion polymerization method from a water glass. A water-in-oil emulsion, in which droplets of a silicic acid solution are emulsified with span 80 (surfactant) in n-hexane, was produced by a high power homogenizer. After gelation, the surface of the spherical silica hydrogels was modified using a TMCS (trimethylchlorosilane)/n-hexane solution followed by solvent exchange from water to n-hexane. Hydrophobic silica wet gel droplets were dried at 80 ℃ under ambient pressure. A perfect spherical silica aerogel powder between1 to 12 ㎛ in diameter was obtained and its size can be controlled by mixing speed. The tapping density, pore volume, and BET surface area of the silica aerogel powder were approximately 0.08 g·cm-3, 3.5 ㎤·g-1 and 742 ㎡·g-1, respectively.

• Korean Journal of Food Science and Technology
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• v.37 no.6
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• pp.1018-1023
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• 2005

Simplified procedure was developed for concentrating and detecting poliovirus and norovirus in oysters. Viruses were seeded into oyster tissue homogenates and concentrated through polyethylene glycol (PEG) precipitation, chloroform or Freon extraction, with additional PEG precipitation. Amount of viruses was evaluated using poliovirus plaque assay. Virus recovery during concentration procedure was approximately 16.4-26.0%. For defection, viral RNAs in oysters were examined using one-step RT-PCR after extraction with Trizol. Dilution or capturing of viral RNA using silica gel membrane allowed viruses to be detected by RT-PCR, whereas viruses could not be removed using $QIAshredder^{TM}$ Homogenizer, which is effective in removing RT-PCR inhibitors in lettuce and hamburgers. Freon extraction, generally used to concentrate viruses found in food, could be substituted with chloroform extraction using this procedure; no difference could be observed between detection limits of whole oyster extracts and digestive organ extracts indicating that RT-PCR inhibitors were distributed evenly throughout whole tissues. Nested PCR greatly improved efficiency of this procedure. Overall, this procedure could remove sufficient amount of inhibitors to allow detection of norovirus in oysters.

• Korean Chemical Engineering Research
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• v.51 no.4
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• pp.482-486
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• 2013

Recently, biohydrocarbons are gathering an interest as a new bioenergy due to the versatile applicability. In the present work, a process is proposed for the recovery of lipids from Recombinant E. coli MG1655 which provides longer chain fatty acids. After the growth of the recombinant E. coli, the cells were disrupted by high pressure homogenizer for obtaining intracellular lipids and the resulting solutions were centrifuged and extracted. For the efficient cell disruption with high pressure homogenizer, the pressure higher than 5,000 psi was required. In addition, under the conditions of applied pressure 5,000 to 20,000 psi, 1~3 pass homogenizing was enough for the more than 90% cell disruption. As organic solvents for extraction of lipid, hexane/isopropyl alcohol and ethyl acetate/ethanol systems showed excellent extracting power. With these solvent systems, the 60% lipid could be recovered. Moreover it was found that the extracted lipids contained long-chain fatty acids such as $C_{12}$, $C_{14}$, $C_{16}$ and $C_{18}$.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.35 no.2
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• pp.79-89
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• 2009

The objective of this study was to find out the stable formulation of nano-emulsion containing high concentration of quercetin and to investigate the effect of an ethanol on the nano-emulsion prepared by POE (30) hydrogenated castor oil (HCO-30)/oil/quercetin/ethanol/water system. Nano-emulsion was prepared using emulsion inversion point (EIP) method as low-energy method plus homogenizer as high-energy method. To evaluate effect of ethanol and other components on the nano-emulsion, physical properties such as droplet size, morphology, and size distribution were determined. The optimal quercetin concentration was 0.2 % on the nano-emulsion. The droplet diameter was below 300 nm at the HCO-30 concentration below 2.00 %. Nano-emmulsion containing 4.75 % HCO-30 was the most stable and its mean droplet size was 172.40 nm. Finally, the size of nano-emulsion containing 4.00 % ethanol was 128.15 nm and size distribution was also narrow. The results showed that the breakdown process of this nano-emulsion could be attributed to Ostwald ripening. This study about effect of ethanol on the nano-emulsion showed that loading capacity of drug could be increased by using a small amount of ethanol. As prepared stable nano-emulsion, this study showed that these results could be applied to pharmaceutics, cosmetic including skin-care products, perfume and etc.

• Journal of the Korean Society of Marine Environment & Safety
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• v.19 no.5
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• pp.518-524
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• 2013

In this study, we conducted a study on characteristics of exhaust gas emissions from boiler when water-bunker oil mixed by homogenizer was burned in boiler. The results showed that NOx concentration and CO concentration of the homogenized bunker oil was decreased by 19% and 54% compared to pure bunker oil pretreatment was not being performed. And, in the case of water-bunker A oil, the NOx concentration was decreased with increasing water mixing ratio in bunker A oil. In particular, the NOx concentration in exhaust gas of 20 %water-80 %bunker A oil decrease by 45 % compared with pure bunker-A. However, the CO concentration in exhaust gas of 20 %water-80 %bunker A oil shows irregular changes. This means that the mixing of water more than a certain amount can cause a decrease in combustion performance. From this result, it can be found that critical mixing ratio of water in bunker A oil for normal combustion is 15% in this study. Deposition amount of soot that is collected in the vicinity of the chimney was decreased with increasing water mixing ratio.