KSBB Journal

  • 제26권5호
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  • Pages.381-385
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  • 2011
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  • 1225-7117(pISSN)
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  • 2288-8268(eISSN)
한국생물공학회 (The Korean Society for Biotechnology and Bioengineering)
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Haematococcus pluvialis 유래 아스타잔틴의 리포좀 캡슐화가 코스메슈티컬 소재로서의 안정성에 미치는 영향

Effect of Liposomal Encapsulation of Astaxanthin from Haematococcus pluvialis on Stabilities for Cosmeceuticals

  • 이정현 (아주대학교 대학원 응용생명공학과 화장품과학전공) ;
  • 김동명 (한국콜마(주) 피부과학연구소) ;
  • 변상요 (아주대학교 대학원 응용생명공학과 화장품과학전공)
  • Lee, Chung-Hyun (Cosmetic Science Major, Applied Biotechnology Department, Graduate School, Ajou University) ;
  • Kim, Dong-Myung (R&D Center, Kolmar Korea) ;
  • Byun, Sang-Yo (Cosmetic Science Major, Applied Biotechnology Department, Graduate School, Ajou University)
  • 투고 : 2011.09.15
  • 심사 : 2011.10.12
  • 발행 : 2011.10.31
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초록

Studies were made to improve the stability of astaxanthin which has application limitations caused by light and thermal stability problems in spite of its strong anti-oxidant property. Astaxanthin was extracted from Haematococcus pluvialis with supercritical carbon dioxide. Liposomal encapsulation of astaxanthin to improve the stability was made with high pressure homogenizer. The narrow size distribution was observed with astaxanthin liposomes. Tests on light and thermal stabilities resulted that the liposormal encapsulation improved the stability of astaxanthin for cosmeceutical purposes.

키워드

참고문헌

  1. Park, E. K., M. W. Seo, and C. G. Lee (2001) Effects of medium copositions for the growth and the astaxanthin production of Haematococcus pluvialis. Kor. J. Appl. Microbiol. Biotechnol. 29: 4227-4233.
  2. Becker, E. W. (1994) Microalgae: Biotechnology and Microbiology, Cambridge University Press, Cambridge, UK.
  3. Bon, J. A., T. D. Leathers, and R. K. Jayaswal (1997) Isolation of astaxanthin-overproducing mutants of Phaffia rhodozyma. Biotechnol. Lett. 19: 109-112. https://doi.org/10.1023/A:1018391726206
  4. Borrowitzka, M. A. (1997) Microalgae for aquaculture: opportunities and constraints. J. Appl. Phycol. 9: 393-401. https://doi.org/10.1023/A:1007921728300
  5. Borowitzka, M. A. (1999) Commercial production of microalgae: ponds, tanks, and fermenters. J. Biotechnol. 70: 313-321. https://doi.org/10.1016/S0168-1656(99)00083-8
  6. Borowitzka, M. A. and L. J. Borowitzka (1988) Micro-algal Biotechnology. Ambridge University Press, Cambridge, UK.
  7. Britton, G., R. J. Weesie, D. Askin, J. D. Warburton, L. Gallardo- Guerrero, F. J. Jansen, H. J. M. D. Groot, J. Lugtenburg, J. P. Cornard, and J. C. Merlin (1997) Carotenoid blues: structural studies on carotenoproteins. Pure Appl. Chem. 69: 2075-2084. https://doi.org/10.1351/pac199769102075
  8. Seki, T., H. Sueki, H. Kono, K. Suganuma, and E. Yamashita (2001) Effects of astaxanthin from haematococcus pluvialis on human skin. Patch testing skin repeated application test effect on wrinkle reduction. Fragrance Journal 12: 98-103.
  9. Arakane, K. (2002) Superior skin protection via astaxanthin. Crotenoid Research 5: 21-24.
  10. Fujita, T., M. Satake, T. Watanabe, C. Kitajima, W. Miki, K. Yamaguchi, and S. Konosu (1983) Pigmentation of cultured red sea bream with astaxanthin purified from krill oil. Nippon Suisan Gakkaishi 49: 1855-1869. https://doi.org/10.2331/suisan.49.1855
  11. Johnson, E. A. (1991) Astaxanthin from microbial sources. Crit. Rev. Biotechnol. 11: 297-326. https://doi.org/10.3109/07388559109040622
  12. Nelis, H. J. and A. P. De Leenheer (1991) Microbial sources of carotenoid pigments used in foods and feeds. Journal of Applied Bacteriology 70: 181-191. https://doi.org/10.1111/j.1365-2672.1991.tb02922.x
  13. Lyons, N. M. and N. M. O'Braen, (2002) Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. J. Dermatol. Sci. 30: 73-84. https://doi.org/10.1016/S0923-1811(02)00063-4
  14. Fang, T. J. and Y. S. Cheng (1993) Improvement of astaxanthin production by Phaffia rhodozyma through mutation and optimization of culture conditions. J. Ferment Bioeng. 75: 466-469. https://doi.org/10.1016/0922-338X(93)90099-T
  15. Palozza, P. and N. I. Krinsky (1992) Astaxanthin and canthaxanthin are potent antioxidants in a membrane model. Arch. Biochem. Biophys. 297: 291-295. https://doi.org/10.1016/0003-9861(92)90675-M
  16. Miki, W. (1991) Biological functions and activities of animal carotenoids. Pure Appl. Chem. 63: 141-146. https://doi.org/10.1351/pac199163010141
  17. Kobayashi, M. and Y. Sakamoto (1999) Singlet oxygen quenching ability of astaxanthin esters from the green alga, Haematococcus pluvialis. Biotechnology Letters 21: 265-269. https://doi.org/10.1023/A:1005445927433
  18. Rattray, J. B., A. Schibeci, and D. K. Kidby (1975) Lipids of yeasts. Bacteriol. Rev. 39: 197-231.
  19. Chisti, Y. and M. Y. Murray (1986) Disruption of microbial cells for intracellular products. Enzyme Microb. Technol. 8: 194-203. https://doi.org/10.1016/0141-0229(86)90087-6
  20. Johnson, E. A., T. G. Villa, M. J. Lewis, and H. J. Phaff (1978) Simple method for the isolation of astaxanthin from the basidiomycetous yeast Phaffia rhodozyma. Appl. and Environ. Microbiol. 35: 1155-1159.