• The Journal of Korean Society for Radiation Therapy
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• v.33
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• pp.89-97
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• 2021

Purpose: The purpose of this study is to compare and evaluate the dose change according to the gas volume variations in the rectum, which was not included in the treatment plan during radiation therapy for cervical cancer. Materials and methods: Static Intensity Modulated Radiation Therapy (S-IMRT) using a 9-field and Volumetric Modulated Arc Therapy (VMAT) using 2 full-arcs were established with treatment planning system on Computed Tomography images of a human phantom. Random gas parameters were included in the Planning Target Volume(PTV) with a maximum change of 2.0 cm in increments of 0.5 cm. Then, the Conformity Index (CI), Homogeneity Index (HI) and PTV D_max for the target volume were calculated, and the minimum dose (D_min), mean dose (D_mean) and Maximum Dose (D_max) were calculated and compared for OAR(organs at risk). For statistical analysis, T-test was performed to obtain a p-value, where the significance level was set to 0.05. Result: The HI coefficients of determination(R²) of S-IMRT and VMAT were 0.9423 and 0.8223, respectively, indicating a relatively clear correlation, and PTV D_max was found to increase up to 2.8% as the volume of a given gas parameter increased. In case of OAR evaluation, the dose in the bladder did not change with gas volume while a significant dose difference of more than D_mean 700 cGy was confirmed in rectum using both treatment plans at gas volumes of 1.0 cm or more. In all values except for D_mean of bladder, p-value was less than 0.05, confirming a statistically significant difference. Conclusion: In the case of gas generation not considered in the reference treatment plan, as the amount of gas increased, the dose difference at PTV and the dose delivered to the rectum increased. Therefore, during radiation therapy, it is necessary to make efforts to minimize the dose transmission error caused by a large amount of gas volumes in the rectum. Further studies will be necessary to evaluate dose transmission by not only varying the gas volume but also where the gas was located in the treatment field.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.12
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• pp.8176-8186
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• 2015

This research was conducted for the purpose of developing a high-fidelity simulation education program, applying it to clinical field and analyzing this program's effect on nursing college students in order to solve problems being caused from the gap between the adult nursing theoretical class and practical education. As the analysis method, this study developed a scenario including an algorithm for caring hyperkalemia patients, the evaluation check list, and debriefing according to the adult nursing theoretical class's learning goal and measured the high-fidelity simulation program's effect in using the non-equivalent control group pre-test and post-test design. As the results from the analysis, there secured the simulation education program's general properties and dependent variable's homogeneity in the experimental group and the control group. The nursing simulation practice program for hyperkalemia patients showed slight effect on the experimental group compared to the control group in fields such as nursing practice ability, problem solving ability, critical thinking skills, self-confidence of nursing, and knowledge. (t=-83.313, p<.001, t=-3.169, p=.003, t=-2.473, p=.017, t=-4.036, p<.001, t=-5.044, p<.001). High-Fidelity simulation programs in conjunction with an adult nursing theory classes of nursing students nursing practice ability, problem solving ability, critical thinking skills, self-confidence of nursing, and knowledge. This simulation program may be an effective educational method for nursing practice and also support improved quality of nursing education.

• Proceedings of the Korean Vacuum Society Conference
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• 2015.08a
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• pp.188.2-188.2
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• 2015

The presence of the conduction interface in epitaxial $LaAlO_3/SrTiO_3$ thin films has opened up challenging applications which can be expanded to next-generation nano-electronics. The metallic conduction path is associated with two adjacent insulating materials. Such device structure is applicable to frequency-dependent impedance spectroscopy. Impedance spectroscopy allows for simultaneous measurement of resistivity and dielectric constants, systematic identification of the underlying electrical origins, and the estimation of the electrical homogeneity in the corresponding electrical origins. Such unique capability is combined with the intentional control on the interface composition composed of $SrTiO_3$ and $CaTiO_3$, which can be denoted by $SrxCa1-_xTiO_3$. The underlying $Sr_xCa1-_xTiO_3$ interface was deposited using pulsed-laser deposition, followed by the epitaxial $LaAlO_3$ thin films. The platinum electrodes were constructed using metal shadow masks, in order to accommodate 2-point electrode configuration. Impedance spectroscopy was performed as the function of the relative ratio of Sr to Ca. The respective impedance spectra were analyzed in terms of the equivalent circuit models. Furthermore, the impedance spectra were monitored as a function of temperature. The ac-based characterization in the 2-dimensional conduction path supplements the dc-based electrical analysis. The artificial manipulation of the interface composition will be discussed towards the electrical application of 2-dimensional materials to the semiconductor devices in replacement for the current Si-based devices.

• Journal of Radiation Protection and Research
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• v.37 no.4
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• pp.167-172
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• 2012

Jeju Island is a significant area as a reference site of in situ gamma spectrometry because there are a number of open spaces which includes $^{137}Cs$ above a certain level. In this paper, the pasture within the Hallasan National Park was selected as one of the open spaces of Jeju Island. The homogeneity of $^{137}Cs$ at the site was assessed by analysis of variance on count and by radioactivity concentration obtained through in situ gamma spectrometry. For this purpose, the count of a total of 79 points at 3 sites were measured with less than count uncertainty of 5% for 2000 seconds. In the results of the analysis of variance, the 2 sites were homogeneous, and the remaining 1 site can be specified to be homogeneous through the adjustment of measuring range. The distribution of radioactivity concentration calculated by in situ gamma spectrometry were $53.7{\sim}93.2Bq\;kg^{-1}$, $30.5{\sim}61.0Bq\;kg^{-1}$ and $48.8{\sim}102Bq\;kg^{-1}$ at each site.

• Child Health Nursing Research
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• v.20 no.3
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• pp.225-235
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• 2014

Purpose: The purpose of this study was to analysis the effects of nasal Continuous Postive Airway Pressure (nCPAP) for preterm infants using systematic review and meta-analysis. Methods: Thirteen peer-reviewed journals including preterm infants and apnea and nCPAP published between 1973 and 2013 were included. Effect size and statistics of homogeneity were done using STATA 10.0. Results: The design for 9 studies was Randomized Control Trial. In most of studies the pressure of nCPAP was set to 4-6 cm$H_2O$. The effect size of 5 studies for the effect on apnea rate using nCPAP compared to nasal Intermittent Positive Pressure Ventilator (nIPPV) showed that the Standardized Mean Difference (SMD) was -0.11 and was not significantly different (Z=0.41, p=.680). But the difference in nCPAP for nasal Synchronizes Intermittent Positive Pressure Ventilator (nSIPPV) (subgroup) was significant (SMD=-.44). The effect size of 7 studies on effect for ventilator weaning of using nCPAP compared to nIPPV showed the Risk Ratio (RR) as 1.60 and was not significantly different (Z=1.12, p=.268). But the difference between nCPAP and nSIPPV (subgroup) was significant (RR=3.94). Conclusion: The results indicate a need for an advanced care system and suggest continuous studies of apnea in preterm infants.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.28 no.2
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• pp.209-218
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• 1995

Bacteriophage T7 gene 2.5 protein, a single-stranded DNA binding protein, has been implicated in T7 DNA replication, recombination, and repair. Purified gene 2.5 protein has been shown to interact with the phage encoded gene 5 protein (DNA polymerase) and gene 4 proteins (helicase and primase) and stimulates their activities. Genetic analysis of T7 phage defective in gene 2.5 shows that the gene 2.5 protein is essential for T7 DNA replication and growth. T7 phage that contain null mutants of gene 2.5 were constructed by homologous recombination. These mutant phage $(T7\Delta2.5)$ cannot grow in Escherichia coli. After infection of E. coli with $T7\Delta2.5$, host DNA synthesis is shut off, and $T7\Delta2.5$ DNA synthesis is reduced to less than $1\%$ of wild-type phage DNA synthesis (Kim and Richardson, 1993, Proc. Natl. Aca. Sci. USA, 90, 10173-10177). A truncated gene 2.5 protein $(GP2.5-\Delta21C)$ deleted the 21 carboxyl terminal amino acids was constructed by in vitro mutagenesis. $GP2.5-\Delta21C$ cannot substitute for wild-type gene 2.5 protein in vivo; the phage are not viable and exhibit less than $1\%$ of the DNA synthesis observed in wild-type phage-infected cells. $GP2.5-\Delta21C$ has been purified to apparent homogeneity from cells overexpressing its cloned gene. Purified $GP2.5-\Delta21C$ does not physically into「act with T1 gene 4 protein as measured by affinity chromatography and immunoblot analysis. The mutant protein cannot stimulate T7 gene 4 protein activity on RNA-primed DNA synthesis and primer synthesis. These results suggest that C-terminal domain of gene 2.5 protein is essential for protein-protein interactions.

• Journal of the Korean Institute of Landscape Architecture
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• v.36 no.3
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• pp.1-8
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• 2008

The purpose of this study is to understand the conflicts that occurred in the rural village's joint management project. This study examined the perception of conflicts among people working in agricultural related fields. A questionnaire survey was given to collected data from people who participated in nation-wide resrvice training course programs. The content of the questionnaire consisted of the factors of conflict in a rural village and the details recognized by general farmers. The data was collected from October 15 to 23, 2007. 206 samples were used for final analysis from a total of 240 samples. Frequency analysis and T-test between variables were conducted by SPSS 14.0. The results suggest that farmers have a negative perception of the business partnership. Proposal for business partnerships should be avoided because of the conflicts between partners. Accordingly, as farmers don't recognize that their joint project is a business partnership, the likehood of a conflict in the agricultural joint business operation and management is contained. Conflicts mainly exist between a village leader and villagers. The main reasons for conflicts are a lack of interest and lack of communal homogeneity, and lack of methodology to share the benefit of business. It will be necessary to understand the aspects of future conflicts in order to manage joint projects ill agricultural experience villages.

• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.615-629
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• 2020

Conducting Focus Group Interview (FGI), this study examined the roles and discourses of cryptocurrency's online communities and media (legacy media and YouTube), and based on this, the study proposed the direction of cryptocurrency policy. By reviewing previous literature, this study analyzed the characteristics of investors, the online community, and YouTube, which is an investment environment factor. The study figured out the purpose of use and role of the community via interviews with cryptocurrency professional investors and online community members and analyzed main discussion themes of the five top-ranked YouTube channels related to cryptocurrency with the highest number of subscribers. The results suggested that cryptocurrency's investment was led by those who are in their 20s and 30s, the investors preferred and trusted information on new media than legacy media. The online community played the role of emotional homogeneity and empathy, and YouTube mainly performed the informational role. As a result of discourse analysis and interviews, this study argued that the legal stability of cryptocurrency's policy and protection of individual investors are needed. This study's significance indicates that it used various research methods such as literature research, interviews, content analysis of community/YouTube to analyze the informational role and emotional aspects of new media and suggested policy direction of the digital new deal blockchain technology and the fairness of financial industry.

• Research in Community and Public Health Nursing
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• v.9 no.1
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• pp.5-20
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• 1998

The purpose of this study was to develop health promotion programs for middle aged women and to identify the adaptability and the effectiveness of the program in order to provide a model for health promotion programs as a basis for nursing intervention. The research design was a quasi-experimental, nonequivalent control-group pretest -posttest design. The data were collected from October 30 to December 11, 1996. The study subjects were middle aged women residing in Chonju city, with ages from 40 to 59. The experimental group consisted of 42 subjects who were recruited through announcements of the local newspaper. The control group consisted of 49 subjects who were mothers of nursing college students. The health promotion program for middle aged women was based on the Bandura's self efficacy theory and Pender's heath promotion behavior theory consisting of exercise and heath diaries as performance accomplishments as well as education and group sessions as verbal persuasion and vicarious experiences. The study program was provided for 6 weeks, 3 hours a day per week. There was a pretest before the program and a posttest after the 6 week program. The instruments used for the study were a Self Efficacy Scale and a Health Promotion Behavior Scale developed by Park(1995). The data analysis was done by the use of a SPSS/PC. The study results were as follows: 1. In the analysis of the homogeneity between the experimental and control groups, there were significant differences in the socio-demographic characteristics, self efficacy and health promotion behavior. There were significant differences between the experimental and control groups in occupation, the number of children, and the status of involvement in social activities. 2. The first hypothesis, 'The level of self efficacy of the experimental group will be higher than that of the control group.' was supported(F=10.154, p=.002). The second hypothesis, 'The degree of health promotive behaviors in the experimental group will be higher than that of the control group.' was supported(F=17.349, p=.000). 3. There was a significant positive correlation between the self efficacy and the health promotion behaviors in pretest and posttests (pretest: r=.732, p=.000 ; posttest : r=.754, p=.000). 4. The significant variables for health promotion behaviors were religion(t= -1.97, p=.05), family income(F=4.85, p=.00), education level (F=6.38, p=.00) and involvement in social activities(t= -3.06, p=.00) in socio-demographic characteristics. In summary, a heath promotion program based on self efficacy theory has made an improvement on health promotion behaviors. Also, the results show that the higher the level of self efficacy, the better the health promotion is in middle aged women. The study has proved that nurses can provide nursing intervention for the improvement of health promotion in middle aged women through the adaptation of a program increasing the subject's self efficacy level.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2731-2737
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• 2013

Background: This study evaluated the validity and reliability of applying the Katz's Activities of Daily Living (ADL) scale in an Iranian sample of elderly oncologic patients following initial cancer treatment. Materials and Methods: The scale was translated with the forward-backward procedure to give an Iranian version. The ADL scale was then applied in a random sample of 400 oncologic patients aged 60 and older following initial cancer treatment. Assessment of the scale stability was twice, with a 14-days (two weeks) interval, to 30 (of the 400) eligible elderly cancer patients in March 2012. To measure treatment effects, the index was run with 150 patients in a three month recall, following oncology processing. Exploratory and confirmatory factor analysis was performed for assessment of construct validity of the Katz's ADL. Reliability was measured with internal consistency (Cronbach's alpha co-efficient), and test/retest (Spearman's r value) of the instrument. Criterion validity was evaluated by comparing the Katz with Physical Function (PF) subscale of SF 36. Known-group validity was approved by comparing of Katz' ADL between quartile groups of PF subscale of SF 36. Results: In our study the ADL demonstrated a high degree of internal homogeneity (Cronbach's alpha 0.923). There was a high correlation between scores of two time measurement of Katz's ADL (p value of two- related- samples test was 0.3). Construct validity showed a correlation coefficient of 0.572 between the ADL and PF scores. In factor analysis, 2 factors were extracted. Evidence for the reliability of the questionnaire was good and known group validity was approved by significant differences of ADL score between quartiles of the PF subscale of SF36. Conclusions: The results suggest that the Iranian version of ADL applied for oncologic older adult patients following initial cancer treatment is a reliable and a valid clinical instrument and comparable to those reported in other studies.