• The Journal of Korean Medicine
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• v.28 no.4
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• pp.104-113
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• 2007

Background : Amygdalin is abundant in Armeniacae semen, and it is recently reported to treat cancers and relieve pain. But modus operandi of amygdalin at the level of neuron has not been reported, yet. Objective : This study aimed to find out the effect of amygdalin on glycine- and glutamate-induced ion currents in periaqueductal gray (PAG) neurons. And it was investigated that amygdalin participates in the regulation of the descending pain control system in the level of PAG neurons. Method : We investigated that the changes of glycine- and glutamate-induced ion currents in PAG neurons through application of lipopolysaccharides (LPS) and application of amygdalin with LPS by using the nystatin-perforated patch clamp method. Result : Application of LPS on PAG neurons resulted in increased glycine-induced ion current, and in decreased glutamate-induced ion current. In contrast, application of amygdalin with LPS resulted in decreased glycine-induced ion current increased by LPS, and increased glutamate-induced ion current decreased by LPS. Conclusion : Amygdalin from Armeniacae semen controls glycine- and glutamate-induced ion current by LPS in PAG neurons, and it is suggested that amygdalin participates in the regulation of the descending pain control system in the level of PAG neurons.

• Proceedings of the KSME Conference
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• 2001.06a
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• pp.292-297
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• 2001

Composite patch repair of cracked aircraft structures has been accepted as one of improving fatigue life and attaining better structural integrity. Analysis for the stress intensity factor at the skin/stiffener structure with inclined central crack repaired by composite stiffened panels are developed. A numerical investigation was conducted to characterize the fracture behavior and crack growth behavior. In order to investigate the crack growth direction, maximum tangential stress(MTS) criteria is used. The main objective of this research is the validation of the inclined crack patching design. In this paper, the reduction of stress intensity factors at the crack-tip and prediction of crack growth direction are determined to evaluate the effects of various non-dimensional design parameter including; composite patch thickness and stiffener distance. The research on cracked structure subjected to mixed mode loading is accomplished and it is evident that more work using different approaches is necessary.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.41 no.12
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• pp.967-974
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• 2013

Recently the authors had proposed the z-pinning patch concept to simply manufacture z-pinned composite structures at industrial production site and manufactured composite single-lap shear joint specimens using the concept. Through static tensile test on the specimens they had obtained 54~68% improvement of the joint strength. As a sequential study of it, in this study, fatigue test has performed to measure an improvement of joint strength under cyclic loading. The z-pin's material is stainless steel and its surface was specially machined into zagged shapes and chemically corroded to increase the connection force with composite materials. Approximately 98~125% improvement of the joint strength under cyclic loading was obtained.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.5
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• pp.2555-2575
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• 2017

This paper presents a dual exposure fusion method for image enhancement. Images taken with a short exposure time usually contain a sharp structure, but they are dark and are prone to be contaminated by noise. In contrast, long-exposure images are bright and noise-free, but usually suffer from blurring artifacts. Thus, we fuse the dual exposures to generate an enhanced image that is well-exposed, noise-free, and blur-free. To this end, we present a new scale-space patch-match method to find correspondences between the short and long exposures so that proper color components can be combined within a proposed dual non-local (DNL) means framework. We also present a residual filtering method that eliminates the structure component in the estimated noise image in order to obtain a sharper and further enhanced image. To this end, the entropy is utilized to determine the proper size of the filtering window. Experimental results show that our method generates ghost-free, noise-free, and blur-free enhanced images from the short and long exposure pairs for various dynamic scenes.

• Korean Journal of Acupuncture
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• v.18 no.1
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• pp.143-156
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• 2001

Modulatory effect of cAMP-PKA system on inhibitory- and excitatory herbs-induced ion currents were investigated by nystatin-perforated patch clamp method under voltage-clamp condition. Ion currents induced by Bupleuri radix and Coptidis rhizoma were not affected by cAMP-PKA system. Ion current induced by Ecliptae herba was partially inhibited by cAMP-PKA system. Ion currents induced by Aconiti tuber and Boshniakiae herba were inhibitory modulated and ion current induced by Zingiberis rhizoma was excitatory modulated by cAMP-PKA system. Modulation of cAMP-PKA system on ion currents induced by Ginseng radix was fluctuated. In this results, it can be seen generally that excitatory herbs-induced ion currents were modulated by cAMP-PKA system while cAMP-PKA system did not affect inhibitory herbs-induced ion currents.

• Geophysics and Geophysical Exploration
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• v.16 no.1
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• pp.59-62
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• 2013

We formerly reported a new method for the upward continuation of potential field on spherical patch area including Earth's curvature, which has been neglected in most studies on rectangular area with flat Earth assumption. This new method is applicable to downward continuation as well by only assigning corresponding value for the ratio of two radii; $r_2/r_1$, i.e., target radius $r_2$ versus datum radius $r_1$. In addition, the inherent problem of this method due to spherical surface geometry is described, and its one possible remedy is given.

• Journal of Sensor Science and Technology
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• v.19 no.6
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• pp.435-442
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• 2010

Typically, the vital signs that are representing the state of human body, are the body temperature, sphygmus, respiration and blood pressure. The body temperature is the result of metabolic regulation and human steady-state body temperature is maintained from 35.9 to $37.4^{\circ}C$ by heat regulatory center. The body temperature is indicative of infection and especially it should be monitored to requiring intensive care patients or after surgical patients. But, measuring of body temperature to a heavy workload on nursing staff has been recognized. And, the health service of nurse is limited by simple tasks such as the measurement and record of vital sign. In this paper, the body temperature monitoring telemetry system was proposed to prove the recoding and transmission of body temperature patch system according the standard(ISO TS11073-92001). We proposed the transmission protocol to suit the MFER(medical waveform format encoding rules). The telemetry patch system was implemented and it was verified by experiments.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.11a
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• pp.856-859
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• 2005

The OPMT(Orientation-adjustable Patch-type Magnetostrictive Transducer) was proposed as a tool for generating and measuring the ultrasonic Lamb wave in plate type structures. This sensor has a lot of new features compared to the traditional piezo-type ultrasonic transducers. As an example, it does not need any kind of wiring for lunching or measuring ultrasonic waves. But it has also definite limitation for practical usage as a nondestructive testing tool in that it cannot help rotating the direction of ultrasonic wave manually. The idea for 'scanning OPMT' is proposed in this respect. Two kinds of basic ideas for rotating the wave direction not manually but electrically are proposed. The fabrication of the transducer and the testing for Identifying the primary characteristics are done for one of the proposed transducers. The results says that there are the possibilities as a new tool for NDE in that the proposed transducer follows well the characteristics of the traditional OPMT. But there are also the 1imitations to overcome.

• Structural Monitoring and Maintenance
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• v.1 no.3
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• pp.339-356
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• 2014

This study has been motivated to evaluate the practicality of numerical simulation of impedance monitoring for damage detection in steel column connection. In order to achieve the objective, the following approaches are implemented. Firstly, the theory of electro-mechanical (E/M) impedance responses and impedance-based damage monitoring method are outlined. Secondly, the feasibility of numerical simulation of impedance monitoring is verified for several pre-published experimental examples on steel beams, cracked aluminum beams, and aluminum round plates. Undamaged and damaged steel and aluminum beams are simulated to compare to experimental impedance responses. An aluminum round plate with PZT patch in center is simulated to investigate sensitive range of impedance responses. Finally, numerical simulation of the impedance-based damage monitoring is performed for a steel column connection in which connection bolts are damaged. From the numerical simulation test, the applicability of the impedance-based monitoring to the target steel column connection can be evaluated.

• The Korean Journal of Pain
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• v.12 no.2
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• pp.211-216
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• 1999

Background: Transdermal fentanyl patch (TDFP) is a simple, noninvasive analgesic with continuous effect. The aim of this study was to evaluate the postoperative analgesic effect of TDFP. Methods: Sixty healthy patients undergoing cesarean section were divided into 3 groups. Postoperative pain was controlled with different methods; Group I: application of TDFP-$25{\mu}g/hr$, Group II: intramuscular injection of ketoprofen; Group III: continuous epidural block. Pain scores (numerical rating scale, NRS), number of patients who needed additive ketoprofen injections and side effects were recorded at 8, 20, 32, 44 hours postoperatively. Results: There was no significanant difference in pain score between Group I and Group II. The numbers of patients who need additive ketoprofen injections were lower in group I than group II. Pruritis (25%), nausea/vomiting (10%), leg numbness (40%) was experienced in group III, but not in Group I & II. Conclusions: TDFP-$25{\mu}g/hr$ for postoperative pain control is simpler and more convinient than intramuscular injection of analgesics.