• Title/Summary/Keyword: History knowledge

Search Result 1,058, Processing Time 0.025 seconds

Review of the History of Animals that Helped Human Life and Safety for Aerospace Medical Research and Space Exploration

  • Lee, Won-Chang;Kim, Kyu-Sung;Kwon, Young Hwan
    • Korean journal of aerospace and environmental medicine
    • /
    • v.30 no.1
    • /
    • pp.18-24
    • /
    • 2020
  • In 2019, the Aerospace Medical Association of Korea celebrated its 30th anniversary. On the other side of the world, it was also the 62nd anniversary of Russian launch Sputnik 1 of the world's first artificial satellite on October 4, 1957. In additionally, the world, especially the United States was shocked, when on November 3, 1957, Sputnik 2 blasted into Earth orbit with a dog named "Laika"; it was the role of veterinarian's activities for aerospace medical research and exploration. Veterinarians (Vets) are responsible for the health of all the animals for aerospace medicine whether on the ground or in space. Vets can enhance animal and public health and this knowledge of Vets and astronauts can extend their mission durations, go to nearby Earth Asteroids, Mars and other heavenly bodies to study their living and non-living characteristics. This review article is the brief history of the original growth of the veterinarian's activities for the aerospace medical research, in order to stimulate future strategies for improvements in the space life sciences and exploration.

A novel variant of PHEX in a Korean family with X-linked hypophosphatemic rickets

  • Kim, Sejin;Kim, Sungsoo;Kim, Namhee
    • Journal of Genetic Medicine
    • /
    • v.19 no.1
    • /
    • pp.27-31
    • /
    • 2022
  • X-linked dominant hypophosphatemic rickets are the most common form of familial hypophosphatemic rickets resulting from hypophosphatemia caused by renal phosphate wasting, which in turn is a result of loss-of-function mutations in PHEX. Herein, we report a 39-year-old female with short stature and skeletal deformities and 12-month-old asymptomatic daughter. The female has a history of multiple surgical treatments because of lower limb deformities. Her biochemical findings revealed low serum phosphorus levels with elevated serum alkaline phosphatase activity and normal serum calcium levels, suggesting presence of hypophosphatemic rickets. To identify the molecular causes, we used a multigene testing panel and found a mutation, c.667dup (p.Asp223GlyfsTer15), in PHEX gene. To the best of our knowledge, this is a novel mutation. A heterozygous form of the same variant was detected in daughter, who showed no typical symptoms such as bow legs, frontal bossing, or waddling gate, but presented early signs of impaired mineralization in both X-ray and biochemical findings. The daughter was initiated onto early medical treatment with oral phosphate supplementation and an active vitamin D analog. Because the daughter was genetically diagnosed based on a family history before the onset of symptoms, appropriate medical management was possible from early infancy.

The Modern Movement in Architecture in the West Perceived by Park Dongjin and Hong Yunsick in the 1930s (1930년대 박동진과 홍윤식의 서양 근대건축운동 인식)

  • Kim, Hyon-Sob;Kim, Jeyeon
    • Journal of architectural history
    • /
    • v.32 no.1
    • /
    • pp.21-34
    • /
    • 2023
  • The purpose of this research is to investigate Korean architects' perception of the Modern Movement in architecture in the West during the Japanese colonial period, by analyzing two Korean publications in the 1930s: Park Dongjin's 'Present Architectural Tendency' (Dong-A Ilbo, March 1931) and Hong Yunsick's 'Trend in the Thought of Moderne Baukunst' (Chogwang, September 1937). As a result of the investigation, it is confirmed that the two men welcomely accepted the universal modernity, regarding the rational and functional - rather than subjective expressions of the individual - as the key to modern architecture. Although their perception of the Modern Movement in Western architecture was inevitably superficial due to the limited condition of the Japanese colonial period in Korea, there was an obvious advancement in the latter's perception from the former's, reflecting the progress in knowledge of it over the six and a half years between the two. Therefore, it is argued that their 1930s' writings are meaningful as the first Korean publications that illustrate how Korean architectural circles perceived the contemporary architectural movement in the West.

The Duty and Role of Uiseoseubdoggwan(Medical Learning Officer) in the Joseon Dynasty Examined through the Historical Trace of IM Won-jun(任元濬, 1423~1500) (임원준의 사적을 통해 본 조선시대 의서습독관의 직무와 역할)

  • LYU Jeong-ah
    • The Journal of Korean Medical History
    • /
    • v.36 no.1
    • /
    • pp.51-72
    • /
    • 2023
  • IM Won-jun(任元濬, 1423~1500) was an Confucianism Doctor in the former period of Joseon Dynasty. Through IM Won-jun's historical trace we could know the range of Uiseoseubdoggwan(Medical Learning Officer)'s duty not limited to study medical books at that time but extended to medical treat, educate, recommend medical policy, personnel manage, carry out administrative work, carry out all the works concerned with medical books, make new medicines at different official period. Among these after learning duties the Royal Family of the Joseon Dynasty awarded high grades to medical treatment for king and king's mother, but from the viewpoint of advancement of medicine controling the top of medical policy as a chief of Jeonuigam had important meaning. The system of Uiseoseubdoggwan(Medical Learning Officer) in the Joseon Dynasty played the role of cultivating widely the man of ability who leaded medical development by sharing the man of ability between medicine and confucianism which was dominant learning at that time, so the knowledge and professional skill of medicine, Yin-Yang and the Five Elements theory, the spirit of relief of the world were spreaded across to national administration, education, publication culture, putting philosophy of filial piety into practice in the Joseon Dynasty.

A Case Study on the Havruta Method in the Reading the Chinese Classics (하브루타를 적용한 경전강독 수업 사례 연구)

  • LEE Hae-deum;KIM Yong-jin
    • The Journal of Korean Medical History
    • /
    • v.36 no.2
    • /
    • pp.89-98
    • /
    • 2023
  • Objectives: This study applied Havruta, a learner-centered educational method, and verified its effectiveness, to break from the existing mechanical memorization methods of scripture reading classes, which are basic subjects of East Asian medicine at East Asian medicine universities. Method: To this end, D University's scripture reading course was redesigned according to Havruta's teaching model, and Havruta classes were conducted according to the instructional design. Results: As a result of the class, students' Chinese translation ability improved, and they were able to concentrate on class (M=4.24). Through class, they acquired knowledge in the field (M=4.21) and their ability to communicate with others improved (M=4.21). M=4.25), it can be inferred and interpreted that the learner is engaged. Conclusion: The results of this study are examples of applying various teaching and learning methods required in the East Asian medicine evaluation and certification of East Asian medicine at East Asian medicine universities, and can be used as practical basic data that can be applied not only to scripture reading subjects but also to other subjects.

Vaccines development in India: advances, regulation, and challenges

  • Rakshita Salalli;Jyoti Ram Dange;Sonia Dhiman;Teenu Sharma
    • Clinical and Experimental Vaccine Research
    • /
    • v.12 no.3
    • /
    • pp.193-208
    • /
    • 2023
  • One of the most significant medical advancements in human history is the development of vaccines. Progress in vaccine development has always been greatly influenced by scientific human innovation. The main objective of vaccine development would be to acquire sufficient evidence of vaccine effectiveness, immunogenicity, safety, and/or quality to support requests for marketing approval. Vaccines are biological products that enhance the body's defenses against infectious diseases. From the first smallpox vaccine to the latest notable coronavirus disease 2019 nasal vaccine, India has come a long way. The development of numerous vaccines, driven by scientific innovation and advancement, combined with researcher's knowledge, has helped to reduce the global burden of disease and mortality rates. The Drugs and Cosmetics Rules of 1945 and the New Drugs and Clinical Trials Rules of 2019 specify the requirements and guidelines for CMC (chemistry, manufacturing, and controls) for all manufactured and imported vaccines, including those against coronavirus infections. This article provides an overview of the regulation pertaining to the development process, registration, and approval procedures for vaccines, particularly in India, along with their brief history.

Is Hiding Foot and Mouth Disease Sensitive Behavior for Farmers? A Survey Study in Sri Lanka

  • Gunarathne, Anoma;Kubota, Satoko;Kumarawadu, Pradeep;Karunagoda, Kamal;Kono, Hiroichi
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.29 no.2
    • /
    • pp.280-287
    • /
    • 2016
  • Foot and mouth disease (FMD) has a long history in Sri Lanka and was found to be endemic in various parts of the country and constitutes a constant threat to farmers. In Sri Lanka, currently there is no regular, nationwide vaccination programme devised to control FMD. Therefore, improving farmers' knowledge regarding distinguishing FMD from other diseases and ensuring prompt reporting of any suspicion of FMD as well as restricting movement of animals are critical activities for an effective FMD response effort. Therefore, the main purpose of this study was to clarify the relationship between farmers' knowledge levels and their behaviors to establish a strategy to control FMD. In our study, item count technique was applied to estimate the number of farmers that under-report and sell FMD-infected animals, although to do so is prohibited by law. The following findings were observed: about 63% of farmers have very poor knowledge of routes of FMD transmission; 'under-reporting' was found to be a sensitive behavior and nearly 23% of the farmers were reluctant to report FMD-infected animals; and 'selling FMD-infected animals' is a sensitive behavior among high-level knowledge group while it is a non-sensitive behavior among the low-level knowledge group. If farmers would understand the importance of prompt reporting, they may report any suspected cases of FMD to veterinary officials. However, even if farmers report honestly, they do not want to cull FMD-infected animals. Thus, education programs should be conducted not only on FMD introduction and transmission, but also its impact. Furthermore, consumers may criticize the farmers for culling their infected animals. Hence, not only farmers, but also consumers need to be educated on the economic impact of FMD and the importance of controlling an outbreak. If farmers have a high knowledge of FMD transmission, they consider selling FMD-infected animals as a sensitive behavior. Therefore, severe punishment should be levied for selling FMD-infected animals.

Lung Cancer Knowledge among Secondary School Male Teachers in Kudat, Sabah, Malaysia

  • Al-Naggar, Redhwan Ahmed;Kadir, Samiah Yasmin Abdul
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.1
    • /
    • pp.103-109
    • /
    • 2013
  • Background: The objective of this study is to determine knowledge about lung cancer among secondary school male teachers in Kudat, Sabah, Malaysia. Materials and Methods: A cross-sectional study was conducted among three secondary schools located in Kudat district, Sabah, Malaysia during the period from June until September 2012. The protocol of this study was approved by ethics committee of Management and Science University, Malaysia. The aims were explained and a consent form was signed by each participant. Respondents were chosen randomly from each school with the help of the headmasters. Self-administrated questionnaires, covering socio-demographic characteristics and general knowledge of lung cancer, were distributed. Once all 150 respondents completed the questionnaire, they passed it to their head master for collecting and recording. All the data were analyzed using Statistical Package for the Social Sciences (SPSS) version 13. ANOVA and t-test were applied for univariate analysis; and multiple linear regression for multivariate analysis. Results: A total of 150 male secondary school teachers participated in this study. Their mean age was $35.6{\pm}6.5$ (SD); maximum 50 and minimum 23 years old. More than half of the participants were Malay and married (52%, 79%; respectively). Regarding the knowledge about lung cancer, 57.3% of the participants mentioned that only males are affected by lung cancer. Some 70.7% mentioned that lung cancer can be transmitted from one person to another. More than half (56.7%) reported that lung cancer is not the leading cause of death in Malaysian males. As for risk factors, the majority reported that family history of lung cancer is not involved. However, 91.3% were aware that cigarettes are the main risk factor of lung cancer and more than half (52%) believed that second-hand smoking is one of the risk factor of lung cancer. More than half (51.3%) were not aware that asbestos, ionizing radiation and other cancer causing substances are risk factors for lung cancer. Quitting smoking, avoiding second-hand smoking and avoiding unnecessary x-ray image of the chest (53.3%, 96.0%, 87.3%; respectively) are the main preventive measures mentioned by the participants. For the factors that influence the participants knowledge, univariate and multivariate analysis showed that only race was significant. Conclusions: Overall, the knowledge of school male teachers about lung cancer was low. However, few items were scored high: cigarettes are the main risk factor; avoiding second-hand smoking; and avoiding x-rays. Interventions to increase lung cancer awareness are needed to improve early detection behavior. Increase the price of pack of cigarettes to RM 20 and banning smoking in public places such as restaurants are highly recommended as primary preventive measures.

Museum Politics: A Study of Orientalism as Represented in the National Museum of Indonesia (박물관의 정치학: 인도네시아 국립박물관에 표상된 오리엔탈리즘 연구)

  • Song, Seung-Won
    • The Southeast Asian review
    • /
    • v.21 no.1
    • /
    • pp.137-184
    • /
    • 2011
  • This article is aimed at understanding the political narratives represented in the National Museum of Indonesia. Starting initially as a colonial museum, the National Museum of Indonesia functioned as a useful tool for the Dutch colonial force to fuel its imaginations of the colonial territory and the people within it. The Dutch used the cultural display to advertize its benevolent colonial rule. All the while, the museum also inevitably reflected orientalism on the people and the culture of the colony. The republic of Indonesia inherited the colonial museum's practices and its display patterns. The business surrounding the museum also played a key role in the newly-born nation-state laying out a future for its redefined territory and people. Thus, what the colonial force imagined for the colonial territory through the study of museum displays was rather directly transferred to the republic without serious consideration of the decolonization process. Four main characteristics have been seen in the museum displays. The first is an emphasis on the glorious Hindu-Buddha history, from which numerous temples, statues, and jewelry have been found. Secondly, the Islamic period, which spanned between the Hindu-Buddha times to the colonial era, has almost completely been eliminated from the display. Third, the colonial era has been depicted as the time of Europe's exportation of scientific tools and adaption of sophisticated living patterns. Fourth, the images of ethnic groups were represented as being stagnant without reflecting any challenges and responses that these groups had faced throughout history. Looking at these display patterns, it can be concluded that all the dynamic internal developments and anti-colonial resistance that took place during the Islamic and Colonial Era have simply not been represented in the museum display. These display patterns do not reflect the real history or culture of the archipelago. Two considerations are thought to have influenced the neglecting of social realities in the display. The first of which is the Dutch's and Republic's apprehension over the possible political upheaval by the Islamic forces. Yet, more fundamentally, cultural displays themselves are distinct from historical education in that the former pays more attention to business ideas with an aim to attract tourists rather than to project objective historical knowledge. Thus, in cultural displays, objects which work to stimulate fantasies and spur curiosity on archipelagic culture tend to be selected and emphasized. In this process, historical objectivity is sometimes considered less vital. Cultural displays are set up to create more appealing narratives for viewers. Therefore, if a narrative loses its luster, it will be replaced by another flashy and newly-resurrected memory. This fact reveals that museums, as transmitters of historical knowledge, have a certain degree of limitation in playing their role.

Development of Production Information System for Real-time Operation Brass-Pipe Production Machine (동파이프 생산 설비가동의 실시간 생산정보시스템 개발)

  • 정영득;김영균;박주식;강경식
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.27 no.1
    • /
    • pp.1-8
    • /
    • 2004
  • This study intend to make easy modification, even if there is a new job or structure change, by modularizing program and computerize and automation of production control management used in CIM. under the condition where manager control production on the job-site, for increasing connection with other operation and management on the computer by monitoring center computer, recognizing information by computer is needed, it is possible by converting transaction. So this study goal is to make delivery control and order control fast and accurate by finding dynamic history of machine and production information in enterprise without input production and quality information by themselves with quality information system. So production increase and quality improvement are possible by diminishing manager's and producer's work with the result of the study combining POP and CIM, after that, in e-business and m-business period that every enterprise must pass, customer satisfaction and sales promotion are possible with employee's computerizing minds. these study result also can knowledge process condition with theoretical class and have a power in finding a solution with foundation of theoretical knowledge.