• 제목/요약/키워드: Historical control data

검색결과 125건 처리시간 0.023초

Sprague-Dawley 랫드를 이용한 수태능 및 초기배 발생시험의 기초자료연구 (Background Data for Fertility and Early Embryonic Development Study in Sprague-Dawley Rats)

  • 김종춘;이상준;서정은;차신우;김충용;한정희;정문구
    • Toxicological Research
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    • 제18권2호
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    • pp.167-174
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    • 2002
  • Historical control data have been shown to be valuable in the proper interpretation and validation of reproductive toxicology studies. The present data were compiled from rat fertility and early embryonic development studies conducted at Korea Institute of Toxicology during the 1994∼2001 period. These data were assembled in order to provide background information for the general and reproductive data collected in 11 fertility and early embryonic development studies using Sprague-Dawley rats obtain-ing from the Breeding Facility, Korea Institute of Toxicology, Korea. A total of 274 males and 274 females were used in these studies during the eight-year period. Parameters of fertility and early embryonic development included clinical sign, body weights, food consumption, organ weights, estrus cycle, copulation index, precoital time, fertility index, pregnancy index, sperm parameters, and early embryonic development parameters. Most of the values were comparable to the previous historical control data reported by other investigators. These data can be wed not only as a historical data base for the meaningful interpretation of data from reproductive and developmental toxicity studies, but also as a contribution to biological characterization of Sprague-Dawley rats.

Sprague-Dawley 랫드를 이용한 발생독성시험의 기초자료연구 (Historical Control Data for Developmental Toxicity Study in Sprague-Dawley Rats)

  • 김종춘;이상준;배진숙;박종일;김용범;정문구
    • Toxicological Research
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    • 제17권2호
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    • pp.83-90
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    • 2001
  • The background control data were compiled from rat developmental toxicity studies con-ducted at Toxicology Research Center, KRICT during the 1993-1999 period. These data were assembled in order to provide background in formation for the maternal and fetal data collected in 13 developmental toxicity studies using Sprague-Dawley rats. A total of 325 mated females were used in these studies during the seven-year period and overall pregnancy rate of these females was 93.8%. The present background control data included body weights, food consumption, hematological values, and organ weights of pregnant females, caesarean section data, and fetal examination data. These data can be used not only as a historical database for the meaningful interpretation of data from reproductive and developmental toxicity studies, but also as a contribution to biological characterization oj Sprague-Dawley rats.

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Short-Term Wind Speed Forecast Based on Least Squares Support Vector Machine

  • Wang, Yanling;Zhou, Xing;Liang, Likai;Zhang, Mingjun;Zhang, Qiang;Niu, Zhiqiang
    • Journal of Information Processing Systems
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    • 제14권6호
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    • pp.1385-1397
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    • 2018
  • There are many factors that affect the wind speed. In addition, the randomness of wind speed also leads to low prediction accuracy for wind speed. According to this situation, this paper constructs the short-time forecasting model based on the least squares support vector machines (LSSVM) to forecast the wind speed. The basis of the model used in this paper is support vector regression (SVR), which is used to calculate the regression relationships between the historical data and forecasting data of wind speed. In order to improve the forecast precision, historical data is clustered by cluster analysis so that the historical data whose changing trend is similar with the forecasting data can be filtered out. The filtered historical data is used as the training samples for SVR and the parameters would be optimized by particle swarm optimization (PSO). The forecasting model is tested by actual data and the forecast precision is more accurate than the industry standards. The results prove the feasibility and reliability of the model.

생산효율화를 위한 설비보전관리 지원시스템에 관한 연구 -설비보전정보시스템을 중심으로- (A Study on the Equipment Maintenance Management Support System for Production Efficiency)

  • 송원섭
    • 산업경영시스템학회지
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    • 제21권48호
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    • pp.279-289
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    • 1998
  • This study deals with the schemes of design, plan and operate maintenance management support systems and with the engineering approach for the solutions to build the maintenance management for the production efficiency. Maintenance Management Information System(MMIS) is the task that must focus on machinery historical data and planned maintenance action. Also the efficient supporting system in a maintenance management is achieved by database which is based on process of machinery's failure history. Designing method of maintenance management information system, maintenance modules are consisted of six factors ; machinery's historical data, lubrication control, check sheet, repair work, availability report, and performance report(control board and detailed reports), and then operators can rapidly utilize data in work place. In the implementation of designed model, program coding has been developed by Visual Basic 3.0. Data insertion, deletion and updating which perform menu screen is implemented by reading data from database. Implementation model based on LAN environment and related data is stored in Microsoft DBMS.

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실적공사비가 적용된 제주도 도로공사의 물가변동률 영향 분석 (Analysis of Road Construction Projects' Escalation under Historical Data-Based Estimate System in Jeju)

  • 홍정호;이동욱
    • 대한토목학회논문집
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    • 제34권2호
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    • pp.667-676
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    • 2014
  • 본 연구는 제주특별자치도 내 실적공사비가 적용된 도로현장을 중심으로 물가변동에 따른 실적공사비 등락률 산정의 문제점을 분석하기 위하여 실시되었다. 본 연구를 위하여 제주특별자치도 내 9개 도로공사 현장을 중심으로 실적공사비방식, 표준품셈방식, 건설공사비지수방식에 따른 등락률을 비교 분석하였다. 분석결과 9개 현장 중 약 56%인 5개 현장에서 실적공사비의 지수조정률이 표준품셈과 건설공사비지수의 지수조정률에 비해 낮게 산정되었다. 이는 실적공사비가 적용됨에 따라 물가변동으로 인한 계약금액 조정 성립요건이 지연되고 있다는 것을 알 수 있으며, 이에 따라 공사 준공 전 물가변동으로 인한 계약금액 조정횟수의 감소와 함께 물가변동금액 역시 차이를 보일 수 있음을 의미한다. 또한, 건설공사비지수 사례분석 결과, 도로부문에 대한 지수를 적용하여 지수조정률을 산출하였으나 지수조정률이 2.0%~9.4%까지 산정되어 이는 공사금액 및 물가변동 적용시기에 따라 상당한 영향을 미치는 문제점이 나타났다.

1930-40년대 부산·경상지역의 근대 역사문화유산에 사용된 강재의 재료적 특성 (Material Properties of Structural Steel used in Modern Historical Heritage of Busan and Gyeongsang in the 1930-1940s)

  • 안재철;송종목
    • 건축역사연구
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    • 제23권6호
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    • pp.39-46
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    • 2014
  • In this study, we evaluated the chemical and physical properties of structural steel, which is the most basic material for steel structures and reinforcement concrete structures in modern period. We theorized the technical data for the research of technical history of modern heritage structures by analyzing the product system and its quality control of structural steel used in modern historical heritages. The results of this study are as follow; first, the rounded bars were used in most of modern heritage structures. But in the case of Waegwan railroad bridge, the deformed bars were used in spit of not using in Japan after the great earthquake of Kantou. Second, the structural steel was good in terms of quality control, but It has brittle properties because it was not manufactured by heat treatment process.

Do Firms with Historical Loss Disclose Less Social Responsibility Information?

  • YIN, Hong
    • 산경연구논집
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    • 제11권1호
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    • pp.19-28
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    • 2020
  • Purpose: This research aims to empirically investigate the motivation of corporate voluntary disclosure by exploring the impact of historical loss on corporate social responsibility disclosure (CSRD). Research design, data, and methodology: This paper takes Chinese A-share listed firms that issued standalone social responsibility reports during the period of 2009-2017 as a sample. Drawing on extant literature, this paper defines historical loss firms as firms with net profit greater than or equal to 0 and undistributed profit less than 0. The tendency score matching method (PSM) is used to find matching samples for historical loss firms. Then OLS regression is conducted to investigate the relationship between historical loss and corporate social disclosure. Results: The results show that historical loss has a significant positive impact on the quality of corporate social responsibility disclosure. After changing the measurement of independent and dependent variables as well as adopting different matching methods to screen the control group, the results still hold. Further research indicates that the relationship between historical loss and CSRD is influenced by corporate financing constraints and industry competition. Conclusions: This research supports the resource motivation hypothesis of corporate social responsibility disclosure, and provides empirical evidence for regulators to strengthen supervision on corporate disclosure.

자원투입 비용을 고려한 공정관리 작업기간 산정 (Projection of Activity Duration Utilizing Historical Cost Data)

  • 문성우;강상래
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2006년도 정기학술발표대회 논문집
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    • pp.444-447
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    • 2006
  • 건설 프로젝트가 성공적으로 수행되기 위해서는 각종 제반 관리업무가 상호 밀접한 관계성을 유지하면서 프로젝트를 수행해야한다. 이중 공정관리는 인력, 자재, 장비, 원가 등 여러 가지 건설공사에 필요한 자원에 대한 관리업무를 시간적인 흐름 속에서 모델화 시킨 것으로, 공정관리의 원활한 수행은 프로젝트의 성공에 직접적인 영향을 주게 된다. 현행 공정관리 업무 프로세스에서 공사기간의 산정시 가장 중요하게 고려해야 할 점은 작업의 생산성은 투입되는 자원의 양과 질에 의해서 영향을 받으며, 이러한 자원의 특성은 투입비용으로 나타나게 된다는 것이다. 본 논문의 목적은 현장에서 사용되는 인력과 장비 등 자원투입 비용을 중심으로 생산성을 분석하고, 보다 현실성 있게 생산성 테이터를 공정계획의 수립시 작업기간 산정에 활용하는 방안을 제시하는 것이다. 본 연구에서 작업비용은 투입자원의 가격을 기준으로 산정했으며, 투입자원 비용과 작업량을 비교 ${\cdot}$ 검토하여 소요되는 작업기간을 예측한다. 이와 같은 공정데이터의 활용은 데이터베이스를 기반으로 하는 공정관리의 전 단계로써 자원투입 비용을 고려한 공정관리 방안을 제시하고, 이에 대한 타당성을 검토했다.

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Historical Control Data from 4-week Repeated Toxicity Studies in Crj:CD (SD) Rats

  • Lee, Jung-Min;Lee, Min-Ah;Do, Hyeon-Nam;Bae, Re-Ji-Na;Lee, Mi-Ju;Kim, Myoung-Jun;Jang, Ho-Song;Park, Sun-Hee;Lee, Hye-Yeong;Kang, Jin-Seok;Kang, Jong-Koo
    • 대한의생명과학회지
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    • 제18권3호
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    • pp.268-275
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    • 2012
  • Reference ranges of standard experimental parameters are useful for comparisons in toxicology. The aim of this study was to collect data from 4-week repeated toxicity studies in Crl:CD (SD) rats, a strain widely used for toxicity and efficacy research, for establishing domestic reference values. Data on body weight, food consumption; urinalysis, hematological, and blood biochemical parameters; and organ weights were collected from 16 toxicity studies in 220 Crl:CD (SD) rats (110 males and 110 females). The studies had been performed at a single testing facility over the last 3 years and involved animals sourced from a single breeder. The findings were collated as means, standard deviations, percentages, and ranges. Urine volume, uterus weight, eosinophil, and basophil counts, and triglyceride, total bilirubin, and gammaglutamyl transpeptidase levels showed standard deviations of 30% or more. These historical control data would help to interpret the effects of test substances in routine toxicity and efficacy studies.

국내의 연기제어 관련 소방법과 건축법의 변천과정에 관한 연구 (A Study on the Historical Comparative of Smoke Control for Fire Safety Law and Building Law)

  • 김혜원;진승현;권영진
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2017년도 춘계 학술논문 발표대회
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    • pp.97-98
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    • 2017
  • These days the buildings are getting higher, bigger, and in a deep. According to that, it was the Large-Scale casuality by smoke from Daeyeongak Hotel fire in 1971 to Uijeongbu apartment fire in 2015, and the law of smoke control has consistently changed. but the analysis for improving the law isn't working. Therefore on this study, it conducts the analysis of historical comparative about smoke control and it will present the basic data for improving the law of smoke control and in-depth analysis.

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