• Title/Summary/Keyword: Historical control data

Search Result 125, Processing Time 0.025 seconds

Background Data for Fertility and Early Embryonic Development Study in Sprague-Dawley Rats (Sprague-Dawley 랫드를 이용한 수태능 및 초기배 발생시험의 기초자료연구)

  • 김종춘;이상준;서정은;차신우;김충용;한정희;정문구
    • Toxicological Research
    • /
    • v.18 no.2
    • /
    • pp.167-174
    • /
    • 2002
  • Historical control data have been shown to be valuable in the proper interpretation and validation of reproductive toxicology studies. The present data were compiled from rat fertility and early embryonic development studies conducted at Korea Institute of Toxicology during the 1994∼2001 period. These data were assembled in order to provide background information for the general and reproductive data collected in 11 fertility and early embryonic development studies using Sprague-Dawley rats obtain-ing from the Breeding Facility, Korea Institute of Toxicology, Korea. A total of 274 males and 274 females were used in these studies during the eight-year period. Parameters of fertility and early embryonic development included clinical sign, body weights, food consumption, organ weights, estrus cycle, copulation index, precoital time, fertility index, pregnancy index, sperm parameters, and early embryonic development parameters. Most of the values were comparable to the previous historical control data reported by other investigators. These data can be wed not only as a historical data base for the meaningful interpretation of data from reproductive and developmental toxicity studies, but also as a contribution to biological characterization of Sprague-Dawley rats.

Historical Control Data for Developmental Toxicity Study in Sprague-Dawley Rats (Sprague-Dawley 랫드를 이용한 발생독성시험의 기초자료연구)

  • 김종춘;이상준;배진숙;박종일;김용범;정문구
    • Toxicological Research
    • /
    • v.17 no.2
    • /
    • pp.83-90
    • /
    • 2001
  • The background control data were compiled from rat developmental toxicity studies con-ducted at Toxicology Research Center, KRICT during the 1993-1999 period. These data were assembled in order to provide background in formation for the maternal and fetal data collected in 13 developmental toxicity studies using Sprague-Dawley rats. A total of 325 mated females were used in these studies during the seven-year period and overall pregnancy rate of these females was 93.8%. The present background control data included body weights, food consumption, hematological values, and organ weights of pregnant females, caesarean section data, and fetal examination data. These data can be used not only as a historical database for the meaningful interpretation of data from reproductive and developmental toxicity studies, but also as a contribution to biological characterization oj Sprague-Dawley rats.

  • PDF

Short-Term Wind Speed Forecast Based on Least Squares Support Vector Machine

  • Wang, Yanling;Zhou, Xing;Liang, Likai;Zhang, Mingjun;Zhang, Qiang;Niu, Zhiqiang
    • Journal of Information Processing Systems
    • /
    • v.14 no.6
    • /
    • pp.1385-1397
    • /
    • 2018
  • There are many factors that affect the wind speed. In addition, the randomness of wind speed also leads to low prediction accuracy for wind speed. According to this situation, this paper constructs the short-time forecasting model based on the least squares support vector machines (LSSVM) to forecast the wind speed. The basis of the model used in this paper is support vector regression (SVR), which is used to calculate the regression relationships between the historical data and forecasting data of wind speed. In order to improve the forecast precision, historical data is clustered by cluster analysis so that the historical data whose changing trend is similar with the forecasting data can be filtered out. The filtered historical data is used as the training samples for SVR and the parameters would be optimized by particle swarm optimization (PSO). The forecasting model is tested by actual data and the forecast precision is more accurate than the industry standards. The results prove the feasibility and reliability of the model.

A Study on the Equipment Maintenance Management Support System for Production Efficiency (생산효율화를 위한 설비보전관리 지원시스템에 관한 연구 -설비보전정보시스템을 중심으로-)

  • 송원섭
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.21 no.48
    • /
    • pp.279-289
    • /
    • 1998
  • This study deals with the schemes of design, plan and operate maintenance management support systems and with the engineering approach for the solutions to build the maintenance management for the production efficiency. Maintenance Management Information System(MMIS) is the task that must focus on machinery historical data and planned maintenance action. Also the efficient supporting system in a maintenance management is achieved by database which is based on process of machinery's failure history. Designing method of maintenance management information system, maintenance modules are consisted of six factors ; machinery's historical data, lubrication control, check sheet, repair work, availability report, and performance report(control board and detailed reports), and then operators can rapidly utilize data in work place. In the implementation of designed model, program coding has been developed by Visual Basic 3.0. Data insertion, deletion and updating which perform menu screen is implemented by reading data from database. Implementation model based on LAN environment and related data is stored in Microsoft DBMS.

  • PDF

Analysis of Road Construction Projects' Escalation under Historical Data-Based Estimate System in Jeju (실적공사비가 적용된 제주도 도로공사의 물가변동률 영향 분석)

  • Hong, Jeong-Ho;Lee, Dong Wook
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.34 no.2
    • /
    • pp.667-676
    • /
    • 2014
  • This study has conducted case studies in order to suggest alternatives to the historical data-based estimate system. Price fluctuation calculation methods based on historial cost indexes, standard estimate and construction cost indexes were applied to 9 road construction sites in Jeju for an analysis. As a result, in 5 construction sites (about 56% of 9 sites), the index control rate calculated based upon historical data-based estimate system was higher than that calculated based upon standard estimate and construction cost indexes. Thus the establishment of the requirements for the adjustment of contract price due to price fluctuation delays, which leads to a significant difference in price fluctuation amount. And, in an analysis of construction cost indexes, the indexes for road construction were used for calculating index control rate which ranges from 2.0 to 9.4 percent, indicating the time of construction amount and price fluctuation application has a significant influence on index control rate.

Material Properties of Structural Steel used in Modern Historical Heritage of Busan and Gyeongsang in the 1930-1940s (1930-40년대 부산·경상지역의 근대 역사문화유산에 사용된 강재의 재료적 특성)

  • Ahn, Jae-Cheol;Song, Jong-Mok
    • Journal of architectural history
    • /
    • v.23 no.6
    • /
    • pp.39-46
    • /
    • 2014
  • In this study, we evaluated the chemical and physical properties of structural steel, which is the most basic material for steel structures and reinforcement concrete structures in modern period. We theorized the technical data for the research of technical history of modern heritage structures by analyzing the product system and its quality control of structural steel used in modern historical heritages. The results of this study are as follow; first, the rounded bars were used in most of modern heritage structures. But in the case of Waegwan railroad bridge, the deformed bars were used in spit of not using in Japan after the great earthquake of Kantou. Second, the structural steel was good in terms of quality control, but It has brittle properties because it was not manufactured by heat treatment process.

Do Firms with Historical Loss Disclose Less Social Responsibility Information?

  • YIN, Hong
    • The Journal of Industrial Distribution & Business
    • /
    • v.11 no.1
    • /
    • pp.19-28
    • /
    • 2020
  • Purpose: This research aims to empirically investigate the motivation of corporate voluntary disclosure by exploring the impact of historical loss on corporate social responsibility disclosure (CSRD). Research design, data, and methodology: This paper takes Chinese A-share listed firms that issued standalone social responsibility reports during the period of 2009-2017 as a sample. Drawing on extant literature, this paper defines historical loss firms as firms with net profit greater than or equal to 0 and undistributed profit less than 0. The tendency score matching method (PSM) is used to find matching samples for historical loss firms. Then OLS regression is conducted to investigate the relationship between historical loss and corporate social disclosure. Results: The results show that historical loss has a significant positive impact on the quality of corporate social responsibility disclosure. After changing the measurement of independent and dependent variables as well as adopting different matching methods to screen the control group, the results still hold. Further research indicates that the relationship between historical loss and CSRD is influenced by corporate financing constraints and industry competition. Conclusions: This research supports the resource motivation hypothesis of corporate social responsibility disclosure, and provides empirical evidence for regulators to strengthen supervision on corporate disclosure.

Projection of Activity Duration Utilizing Historical Cost Data (자원투입 비용을 고려한 공정관리 작업기간 산정)

  • Moon, Sung-Woo;Kang, Sang-Rae
    • Proceedings of the Korean Institute Of Construction Engineering and Management
    • /
    • 2006.11a
    • /
    • pp.444-447
    • /
    • 2006
  • Construction managers need to pay a close attention to the resource utilization in order to deliver the construction project successfully. Construction scheduling is crucial for resource control in that it provides information when and how much to bring down work force to sites. In scheduling, activity duration is projected based on the productivity of historical data or the intuition of scheduler. This paper studies the opportunity of applying cost-based productivity for estimating activity duration. For cost-based productivity, the cost of resource is used as an input and the work quantities as an output. Out of historical data, regression model has been developed to understand the validity of applying cost-based productivity in projecting activity duration. The result of study will work as a prerequisite for implementing the environment of database-based construction scheduling.

  • PDF

Historical Control Data from 4-week Repeated Toxicity Studies in Crj:CD (SD) Rats

  • Lee, Jung-Min;Lee, Min-Ah;Do, Hyeon-Nam;Bae, Re-Ji-Na;Lee, Mi-Ju;Kim, Myoung-Jun;Jang, Ho-Song;Park, Sun-Hee;Lee, Hye-Yeong;Kang, Jin-Seok;Kang, Jong-Koo
    • Biomedical Science Letters
    • /
    • v.18 no.3
    • /
    • pp.268-275
    • /
    • 2012
  • Reference ranges of standard experimental parameters are useful for comparisons in toxicology. The aim of this study was to collect data from 4-week repeated toxicity studies in Crl:CD (SD) rats, a strain widely used for toxicity and efficacy research, for establishing domestic reference values. Data on body weight, food consumption; urinalysis, hematological, and blood biochemical parameters; and organ weights were collected from 16 toxicity studies in 220 Crl:CD (SD) rats (110 males and 110 females). The studies had been performed at a single testing facility over the last 3 years and involved animals sourced from a single breeder. The findings were collated as means, standard deviations, percentages, and ranges. Urine volume, uterus weight, eosinophil, and basophil counts, and triglyceride, total bilirubin, and gammaglutamyl transpeptidase levels showed standard deviations of 30% or more. These historical control data would help to interpret the effects of test substances in routine toxicity and efficacy studies.

A Study on the Historical Comparative of Smoke Control for Fire Safety Law and Building Law (국내의 연기제어 관련 소방법과 건축법의 변천과정에 관한 연구)

  • Kim, Hye-Won;Jin, Seung-Hyun;Kwon, Young-Jin
    • Proceedings of the Korean Institute of Building Construction Conference
    • /
    • 2017.05a
    • /
    • pp.97-98
    • /
    • 2017
  • These days the buildings are getting higher, bigger, and in a deep. According to that, it was the Large-Scale casuality by smoke from Daeyeongak Hotel fire in 1971 to Uijeongbu apartment fire in 2015, and the law of smoke control has consistently changed. but the analysis for improving the law isn't working. Therefore on this study, it conducts the analysis of historical comparative about smoke control and it will present the basic data for improving the law of smoke control and in-depth analysis.

  • PDF