• Medical Lasers
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• 제8권2호
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• pp.59-63
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• 2019

Background and Objectives High-intensity focused ultrasound (HIFU) has been developed as an effective, non-invasive, skin-tightening method in response to the increasing demand for improvements in skin laxity and tightening with minimal risk and recovery time. This study evaluated the efficacy and safety of HIFU for non-invasive skin tightening of crow's feet wrinkles, with the aim of determining how long the tightening can be maintained. Materials and Methods Between January and March 2019, 21 female patients with crow's feet wrinkles were treated with HIFU. The treatment involved 200 shots, three times every 2 weeks. Three blinded, experienced plastic surgeons and patients evaluated satisfaction at 2 weeks after the first procedure, 2 weeks after the second procedure, 2 weeks after the third procedure, and 6 weeks after the first procedure based on photographs according to the Global Aesthetic Improvement Scale (GAIS). The Friedman test was used to compare data. Results Of the 21 patients treated using HIFU, one was lost to follow-up for nonstudy-related reasons. Therefore, 20 patients were evaluated and ranged in age from 28 to 48 years. Plastic surgeons' GAIS scores were 2.6, 2.3, 1.7, and 1.3 and patients' GAIS scores were 2.6, 2.2, 1.8, and 1.4 at 2 weeks after the first procedure, 2 weeks after the second procedure, 2 weeks after the third procedure, and 6 weeks after the third procedure. No serious adverse effects were observed. Conclusion The aging face with crow's feet wrinkles can be improved by using HIFU, while minimizing epidermal and dermal injury.

• 한국광학회지
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• 제32권3호
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• pp.120-125
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• 2021

본 연구에서는 다파장 빔결합을 위한 master oscillator power amplifier (MOPA) 구조의 선편광 고출력 이터븀 첨가 광섬유 레이저를 개발하였다. 유도 브릴루앙 산란(stimulated Brillouin scattering, SBS)을 억제하기 위하여 pseudo-random binary sequence (PRBS) 신호로 위상 변조 및 비트길이를 최적화한 선폭 약 10 GHz의 시드 레이저를 구현하였으며, 이를 이용하여 3단 증폭을 하였다. 주 증폭단에서는 모드 불안정성 현상(mode instability, MI)의 문턱값을 높이기 위하여 코어 및 클래딩의 직경이 각각 20 ㎛, 40 ㎛인 편광유지(polarization maintaining, PM) 이터븀 첨가 광섬유를 이용하고 지름이 약 9-12 cm인 나선형 홈에 적용하였다. 그 결과, 입사된 여기광 대비 기울기 효율이 83.7%인 1.004 kW의 레이저 출력을 얻었다. 또한, 빔품질(M²)과 편광소광율(polarization extinction ratio, PER)은 각각 1.12와 21.5 dB로 측정되었다. 더욱이, 역방향 스펙트럼의 레일리 신호와 SBS 신호의 첨두 세기 비율은 2.36 dB로 관측되어, SBS가 완화된 레이저 구현을 확인하였다. 또한 증폭 출력에 따라 기울기 효율 및 빔품질의 저하가 없어 모드불안정이 발생하지 않음을 확인하였다.

• Molecules and Cells
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• 제43권3호
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• pp.298-303
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• 2020

Cryo-electron microscopy (cryo-EM) is now the first choice to determine the high-resolution structures of huge protein complexes. Grids with two-dimensional arrays of holes covered with a carbon film are typically used in cryo-EM. Although semi-automatic plungers are available, notable trial-and-error is still required to obtain a suitable grid specimen. Herein, we introduce a new method to obtain thin ice specimens using real-time measurement of the liquid amounts in cryo-EM grids. The grids for cryo-EM strongly diffracted laser light, and the diffraction intensity of each spot was measurable in real-time. The measured diffraction patterns represented the states of the liquid in the holes due to the curvature of the liquid around them. Using the diffraction patterns, the optimal time point for freezing the grids for cryo-EM was obtained in real-time. This development will help researchers rapidly determine high-resolution protein structures using the limited resource of cryo-EM instrument access.

• Journal of Advanced Marine Engineering and Technology
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• 제25권6호
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• pp.1281-1290
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• 2001

A study on the fluid flow with ultrasonic forcing is carried out to obtain data for the turbulence enhancement. A large water tank is made of the transparent acrylic plates and a horizontal flow field is given by setting two acrylic tubes to face mutually on a horizontal line. A 2-dimensional PlV system which is composed of a continuous-output 4W Argon-ion laser, a high-speed video camera, a PC based by an image grabber and a high resolution monitor is used to investigate characteristics of the complex turbulence flow field. And a 2MHz ultrasonic transducer is used fur ultrasonic vibration forcing. Some experiments are carried out at Reynolds numbers of 2,000 and 4,000 and at 7 angles of ultrasonic incidence. In results, the flew velocity vector distribution, kinetic energy and turbulence intensity in both cases of with and without ultrasonic forcing are examined, compared and discussed by using PIV measurement. It is clarified that the ultrasonic forcing into flow field is valid to obtain the turbulence enhancement.

• KIEE International Transactions on Electrophysics and Applications
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• 제11C권3호
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• pp.63-69
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• 2001

Holographic transmission gratings were performed by an Ar-laser( ${\lambda}$=514nm) intensity, the ratio fo LC contents to the surfactant. The addition of the surfactant to the LC and pre-polymer systems causes the droplet to maintain the ideal size at the high fraction(over 40wt%) of the LC contents that induce the films to be fabricated with high diffraction efficiency than that of no surfactant series. The image of these films was examined using a charge coupled device (CCD). We also studied the angular selectivity plots which support the important role in the multiplexer channel (MUX). Eventually, we showed the reconstructive optical image recorded in this transmission mode of HPDLCs.

• Journal of the Optical Society of Korea
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• 제7권3호
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• pp.145-149
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• 2003

The anisotropy of electron energy distribution in oxygen plasmas produced by a high intensity laser was investigated by using polarization spectroscopy. An ultra-short pulsed laser with a pulse duration of 66.5 fs and a power density of $1 {\times} 10^17/ W/$\textrm{cm}^2$$ was used. At this power density and pulse duration, the plasma was generated predominantly by optical field ionization. The degree of polarization of OVI 1s$^2$2p$^2$p2- 1s$^2$4d$^2$D$^{0}$ (J = 1/2-3/2 and 3/2-5/2) transition line at 129.92 $\AA$ was measured. O VI 1s$^2$2p$^2$P$^2$ -1s$^2$4s$^2$S$^2$ (J = 1/2-1/2 and 3/2-1/2) transition line at 132.26 $\AA$ was used to calibrate the sensitivity of the optical system. The dependencies of the degree of polarization on the initial gas density and on the laser polarization were investigated. When the laser polarization was changed from a linear to a circular polarization, the degree of polarization was decreased. When the initial gas density was increased, the degree of polarization was decreased.

• 한국전기전자재료학회논문지
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• 제21권8호
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• pp.760-765
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• 2008

Low power laser therapy is internationally certified and is known to be effective in stimulating DNA in living organisms, increasing protein synthesis and activating cell division, smoothing blood circulation, promoting cell activation, cell regeneration and function. It also has anti-inflammatory, anti-edemic, anti-fibrous dysplastic and neuralogic hyperfunctional effects. This study was intended to verify the effect of LED irradiation therapy on wound healing in cell and animal tests by applying LED irradiator using a laser and laser diode, which was independently designed and developed to emit beams of similar wavelength to that of a laser. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity and reservation. In case of cell proliferation experiment, each experiment was performed to irradiation group and non-irradiation group for tissue cells. MTT assay method was chosen to verify the cell increase of two groups and the effect of irradiation on cell proliferation was examined by measuring 590 nm transmittance of micro-plate reader. In the wound healing experiment, 1$cm^2$ wounds on the skin wound of SD-Rat(Sprague-Dawley Rat) were made. Light irradiation group and none light irradiation group divided, each group was irradiated one hour a day for 9 days. As a result, the cell increase of tissue cells was verified in irradiation group as compared to non-irradiation group. And, compared with none light irradiation group, the lower incidence of inflammation and faster recovery was shown in light irradiation group.

• 한국광학회지
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• 제10권2호
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• pp.107-113
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• 1999

수차가 적은 홀로그래픽 스캐너는 기존의 렌즈나 거울과 같은 광학 소자의 사용 매수를 줄임으로써 제작 가격을 낮출 수 있다는 잠재적인 장점을 갖고 있다. 본 연구에서는 홀로그래픽 스캐너 설계에 광선 추적버블 적용하여 스캔 기능과 초점을 맺는 기능을 동시에 할 수 있는 홀로그래픽 광학 소자를 설계하였으며, 수차가 없는 직선의 스캔 라인을 얻기 위한 기록 및 재생 구조와 hologon 구조에 대해 조사하였다. Prototype으로 제작된 홀로그래픽 스캐너에서 bow는 전체 스캔 폭 300 mm에서 $\pm$133$\mu\textrm{m}$이었으며, spot의 크기는 100 $\mu\textrm{m}$ 이하로 얻을 수 있었다. 실험 결과 광선 추적을 이용한 설계 데이터의 유용성을 검증하였고 레이저 프린터나 디스플레이 분야 등으로의 응용 가능성을 제시하였다.

• 한국지능시스템학회논문지
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• 제22권4호
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• pp.521-526
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• 2012

제조공정을 통해 생산된 화살의 성능은 화살의 이동궤적(궁사의 패러독스)과 탄착점의 집적도에 따라 좌우된다. 특히 동일한 환경에서 반복적으로 화살의 슈팅실험을 수행할 경우, 반복실험에서 얻어진 화살의 탄착점 집적도는 화살 성능 평가에서 중요한 객관적 지표가 된다. 그러나 화살의 탄착점에 대한 분석은 현재 상용화된 기술이 부족하며, 기존의 연구들은 화살의 성능에 영향을 미치는 제조공정 변수(화살깃, 화살촉, 화살의 곧기, 중량, 외경, 스파인)만을 최적화하려는 방향으로 기술력이 집중되어 있다. 본 논문에서는 화살의 주요성능지표인 화살의 탄착점 측정 자동화를 위해, Mamdani 퍼지 추론 시스템(Mamdani Fuzzy Inference System)과 도형의 닮음(Similarity of Polygon)을 이용한 화살의 탄착점 측정 시스템을 제안한다. 라인레이저(Line Laser)와 포토다이오드어레이(Photo Diode Array)를 이용하여 고속(약 275km/h)으로 이동하는 화살의 탄착점 데이터를 계측하고, 계측된 데이터를 퍼지 추론과 도형의 닮음을 이용하여 화살의 탄착점으로 사상(Mapping) 시킨다.

• Transactions on Electrical and Electronic Materials
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• 제4권6호
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• pp.13-16
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• 2003

Mn-doped $ZnGa_{2}O_{4}$:$Mn^{2+}$ (M=S, Se) thin film phosphors have been grown using a pulsed laser deposition technique under various growth conditions. The structural characterization carr~ed out on a series of $ZnGa_{2}O_{4}$:$Mn^{2+}$ (M=S, Se) films grown on MgO(l00) substrates usmg Zn-rich ceramic targets. Oxygen pressure was varied from 50 to 200 mTorr and Zn/Ga ratio was the function of oxygen pressure. XRD patterns showed that the lattice constants of the $ZnGa_{2}O_{4}$:$Mn^{2+}$ (M=S, Se) thin film decrease with the substitution of sulfur and selenium for the oxygen in the $ZnGa_2O_4$. Measurements of photoluminescence (PL) properties of $ZnGa_{2}O_{4}$:$Mn^{2+}$ (M=S, Se) thin films have indicated that MgO(100) is one of the most promised substrates for the growth of high quality $ZnGa_2O_{4-x}M_{x}$:$Mn^{2+}$ (M=S, Se) thin films. In particular, the incorporation of Sulfur or Selenium into $ZnGa_2O_4$ lattice could induce a remarkable increase in the intensity of PL. The increasing of green emission intensity was observed with $ZnGa_2O_{3.925}Se_{0.075}:$Mn^{2+}$ and $ZnGa_2O_{3.925}S_{0.05}$:$Mn^{2+}$ films, whose brightness was increased by a factor of 3.1 and 1.4 in comparison with that of $ZnGa_{2}O_{4}$:$Mn^{2+}$ films, respectively. These phosphors may promise for application to the flat panel displays.