• Journal of Ginseng Research
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• 제43권4호
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• pp.580-588
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• 2019

Background: Ginsenoside Rg1 has been shown to clear senescence-associated beta-galactosidase (SA-${\beta}$-gal) in cultured cells. It remains unknown whether Rg1 can influence SA-${\beta}$-gal in exercising human skeletal muscle. Methods: To examine SA-${\beta}$-gal change, 12 young men (age $21{\pm}0.2years$) were enrolled in a randomized double-blind placebo controlled crossover study, under two occasions: placebo (PLA) and Rg1 (5 mg) supplementations 1 h prior to a high-intensity cycling (70% $VO_{2max}$). Muscle samples were collected by multiple biopsies before and after cycling exercise (0 h and 3 h). To avoid potential effect of muscle biopsy on performance assessment, cycling time to exhaustion test (80% $VO_{2max}$) was conducted on another 12 participants (age $23{\pm}0.5years$) with the same experimental design. Results: No changes of SA-${\beta}$-gal were observed after cycling in the PLA trial. On the contrary, nine of the 12 participants showed complete elimination of SA-${\beta}$-gal in exercised muscle after cycling in the Rg1 trial (p < 0.05). Increases in apoptotic DNA fragmentation (PLA: +87% vs. Rg1: +133%, p < 0.05) and $CD68^+$ (PLA:+78% vs. Rg1:+121%, p = 0.17) occurred immediately after cycling in both trials. During the 3-h recovery, reverses in apoptotic nuclei content (PLA:+5% vs. Rg1 -32%, p < 0.01) and increases in inducible nitrate oxide synthase and interleukin 6 mRNA levels of exercised muscle were observed only in the Rg1 trial (p < 0.01). Conclusion: Rg1 supplementation effectively eliminates senescent cells in exercising human skeletal muscle and improves high-intensity endurance performance.

• 디지털융복합연구
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• 제20권1호
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• pp.191-202
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• 2022

본 연구의 목적은 고등학교 남자 축구선수 24명을 대상으로 10주간 신체안정화운동 프로그램 중재 후 기술체력에 미치는 영향을 규명하는 것이다. 블레이즈포드로 시각반응속도 검사를 시행한 결과 위팔, 왼발, 오른발의 15초간 반응횟수와 반응시간(p<0.001)은 유의하게 증가하였다. 기능적 움직임 평가하기 위해 7가지 동작의 향상 여부 평가결과 허들건너기(p<0.001), 능동적폄다리올리기(p=0.022) 동작이 유의하게 향상되었다. 균형능력을 평가하기 위해 와이발런스 평가결과 양쪽 복합점수(p<0.001)가 유의하게 향상하였다. 기동력과 근지구력을 평가하기 위해 폐활량 측정결과 노력성폐활량(p<0.001)과 1초간 강제날숨량(p=0.003)이 유의하게 향상되었다. 10주간 신체안정화운동 중재 후, 경기에 필요한 기술 체력인 순발력, 민첩성, 다리 근력, 다리의 안정성, 기동력, 근지구력을 효과적으로 향상할 수 있다는 결론을 얻었고, 이러한 기술체력의 향상은 축구선수들의 부상을 방지할 수 있으며, 경기력을 향상할 수 있을 것이다.

• 한국군사과학기술학회지
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• 제14권1호
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• pp.132-138
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• 2011

A micromachined silicon accelerometer capable of surviving and detecting very high accelerations(up to 200,000 times the gravitational acceleration) is necessary for a high impact accelerometer for earth-penetration weapons applications. We adopted as a reference model a piezoresistive type silicon micromachined high-shock accelerometer with a bonded hinge structure and performed structural analyses such as stress, modal, and transient dynamic responses and sensor sensitivity simulation for the selected device using piezoresistive-structural coupled-field analysis. In addition, structural optimization was introduced to improve the performances of the accelerometer against the initial design of the reference model. The design objective here was to maximize the sensor sensitivity subject to a set of design constraints on the impact endurance of the structure, dynamic characteristics, the fundamental frequency and the transverse sensitivities by changing the dimensions of the width, sensing beams, and hinges which have significant effects on the performances. Through the optimization, we could increase the sensor sensitivity by more than 70% from the initial value of $0.267{\mu}V/G$ satisfying all the imposed design constraints. The suggested simulation and optimization have been proved very successful to design high impact microaccelerometers and therefore can be easily applied to develop and improve other piezoresistive type sensors and actuators.

• 운동영양학회지
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• 제23권4호
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• pp.36-42
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• 2019

[Purpose] The study aimed to determine the effects of bone-specific physical activity on body composition, bone mineral density (BMD), and health-related physical fitness in middle-aged women. [Methods] One hundred eighty-six middle-aged women aged 31-49 years participated in this study. The subjects were divided into tertile groups according to the level of physical activity (low-score group, n=62; middle-score group, n=62; high-score group, n=62). Bone-specific physical activity participation was assessed using the bone-specific physical activity questionnaire. Body composition and BMD were measured using dual-energy X-ray absorptiometry. Health-related physical fitness test included isometric muscle strength (grip strength), muscular endurance (sit-ups), flexibility (sit and reach), and cardiorespiratory fitness (maximal oxygen uptake [VO_2max]). [Results] The high-score group had a significantly higher fat-free mass (p=.045, partial eta-squared value[η_p²]=.033) than the middle- and low-score groups, whereas the high-score group had significantly lower percent body fat (p=.005, η_p²=.056) than the other two groups. Whole-body BMD (p=.034, η_p²=.036) and lumbar BMD (p=.003, η_p²=.060) were significantly higher in the high-score group than in the low-score group. The high-score group performed significantly better for grip strength (p=.0001, η_p²=.101), sit-ups (p=.0001, η_p²=.108), and VO_2max (p=.0001, η_p²=.092) than the other two groups. [Conclusion] The present study suggests that bone-specific physical activity could be useful in improving body composition, BMD, and health-related physical fitness in middle-aged women, significantly enhancing their BMD and health conditions.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.373-373
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• 2014

Resistive-change random access memory (ReRAM) device is one of the promising candidates owing to its simple structure, high scalability potential and low power operation. Many resistive switching devices using transition metal oxides materials such as NiO, Al2O3, ZnO, HfO2, $TiO_2$, have attracting increased attention in recent years as the next-generation nonvolatile memory. Among various transition metal oxides materials, HfO2 has been adopted as the gate dielectric in advanced Si devices. For this reason, it is advantageous to develop an HfO2-based ReRAM devices to leverage its compatibility with Si. However, the annealing temperature of these high-k thin films for a suitable resistive memory switching is high, so there are several reports for low temperature process including microwave irradiation. In this paper, we demonstrate the bipolar resistive switching characteristics in the microwave irradiation annealing processed Ag/HfO2/Pt ReRAM device. Compared to the as-deposited Ag/HfO2/Pt device, highly improved uniformity of resistance values and operating voltage were obtained from the micro wave annealing processed HfO2 ReRAM device. In addition, a stable DC endurance (>100 cycles) and a high data retention (>104 sec) were achieved.

• 펄프종이기술
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• 제45권4호
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• pp.1-8
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• 2013

High loading of printing and writing grades with fillers has many advantageous aspects in papermaking because it allows decreasing fiber use and reducing manufacturing cost. High loading technology, however, has some disadvantageous aspects as well. It decreases physical properties of papers, especially strength properties. The problem associated with high loading can be reduced by applying surface sizing starch solution onto paper surface. It is important to control the penetration of the surface sizing starch solution into paper web to obtain the desired property improvement. In this study, the effect of the addition of two polymers into starch solution on paper properties has been examined. PVOH and polyDADMAC were used as polymeric additives for surface sizing with oxidized starch. Viscosity of starch solutions and surface roughness of dried starch films on glass slides showed that some interactions between polymeric additives and oxidized starch have been occurred and the most extensive interaction with starch solution was obtained with high molecular weight polyDADMAC. Low molecular weight PVOH was most effective in improving folding endurance and internal bond strength. On the other hand, polymer addition showed no effect on surface strength of paper. This indicates that not the level of starch holdout but the bonding strength of starch itself has predominant influence on surface strength of paper.

• 한국항공우주학회지
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• 제43권12호
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• pp.1035-1047
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• 2015

고고도 장기체공 축소형 전기 동력 무인기(EAV-2H+)용 프로펠러의 성능을 평가하기 위해 풍동시험과 전산해석을 수행하였다. 3종의 프로펠러에 대해 성능 곡선을 측정하고, 운용 조건을 평가하여 EAV-2H+에 적용 가능 여부를 판단하였다. 낮은 rpm 영역에서 성능 계수의 저하 경향을 확인하였다. 프로펠러 성능에 미치는 강체 천이 테이프 부착 효과를 측정하고 분석하였다. 상용 전산유체역학 코드를 사용한 성능 해석을 수행하여 시험과 해석의 추력계수-동력계수 선도가 잘 일치함을 확인하였다. 전진비에 따른 성능 계수를 비교하고 결과 차이에 기여하는 시험장치의 영향을 평가하였다. 시험에서 관찰된 낮은 rpm 영역의 성능 감소 경향을 transition SST 모델이 유사하게 모사함을 확인하였다. 낮은 레이놀즈수에 의한 깃 요소의 공력 성능 저하가 프로펠러 성능 감소의 주원인으로 분석되었다. 고고도 조건 해석으로부터 프로펠러 성능 저하를 확인하였다.

• International Journal of Aeronautical and Space Sciences
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• 제13권4호
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• pp.446-457
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• 2012

Aeroelastic analysis of an aircraft with a high aspect ratio wing for medium altitude and long endurance capability was attempted in this paper. In order to achieve such an objective, various structural models were adopted. The traditional approach has been based on a one-dimensional Euler-Bernoulli beam model. The structural analysis results of the present beam model were compared with those by the three-dimensional NASTRAN finite element model. In it, a taper ratio of 0.5 was applied; it was comprised of 21 ribs and 3 spars, and included two control surfaces. The relevant unsteady aerodynamic forces were obtained by using ZAERO, which is based on the doublet lattice method that considers flow compressibility. To obtain the unsteady aerodynamic force, the structural mode shapes and natural frequencies were transferred to ZAERO. Two types of unsteady aerodynamic forces were considered. The first was the unsteady aerodynamic forces which were based on the one-dimensional beam shape; the other was based on the three-dimensional FEM model shape. These two types of aerodynamic forces were compared, and applied to the foregoing flutter analysis. The ultimate goal of the present research is to analyze the possible interaction between the rigid-body degrees of freedom and the aeroelastic modes. This will be achieved after the development of a reliable nonlinear beam formulation that would validate the current results as well as enable a thorough investigation of the nonlinearity. Moreover, such analysis will allow for an examination of the above-mentioned interaction between the flight dynamics and aeroelastic modes with the inclusion of the rigid body degrees of freedom.

• 대한기계학회논문집A
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• 제34권10호
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• pp.1521-1527
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• 2010

잉크젯 프린팅이 전자 및 디스플레이 산업의 생산라인에 적용됨에 따라, 생산효율을 극대화하기 위해 잉크액적 토출불량 검사 소요시간의 단축이 요구되고 있다. 기존의 잉크액적 토출불량 검사방법은 주로 고배율 렌즈와 CCD 카메라를 직선운동을 하는 스테이지 상에 설치하여 잉크젯 프린트 헤드의 노즐배열과 평행한 방향으로 순차적으로 이동시키면서 토출되는 잉크액적을 비젼검사하는 것이었다. 그러나, 기존 방식은 60 초 혹은 그 이상의 검사시간을 요구하며, 특히 잉크액적 토출불량을 장시간 지속적으로 검사하는 것은 불필요한 기계적 진동을 야기시키는 문제점이 있었다. 본 연구에서는 회전미러 방식의 고속 잉크젯 모니터링 모듈을 설계하여 검사시간을 18 초 내외로 단축하였으며, 검사 소요시간 단축을 위한 모듈의 설계 고려사항들에 대해 논의하도록 한다.

• 한국항공우주학회지
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• 제43권5호
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• pp.396-404
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• 2015

무인기의 날개는 고고도 장기체류에 적합하도록 가로세로비가 크며, 비행 중 구조 대변형이 발생한다. 비행 중 날개 구조의 실시간 변형 상태 파악을 위해 변위-변형률 관계를 이용하여 비행체의 구조 건전성 및 관련 하중 상태 평가, 이상 진동 현상 발견 및 조종성 향상과 같은 영역에서 활용할 수 있다. 본 논문에서는 비행 중 변형이 발생하는 날개 구조물을 외팔보로 가정하여 구조 대변형을 보다 간편하게 예측하기 위한 변형률 기반의 비선형성을 고려한 변위 예측 알고리즘을 작성하였다. 변위 예측식은 외팔보의 다양한 끝단 변위 조건에서 이루어진 구조 실험과 유한요소 해석 결과의 비교를 통하여 검증하였다. 변형률은 스트레인 게이지로부터 취득한 값을 사용하였으며, 변형률을 이용하여 예측된 변위는 레이저 변위 센서로 측정한 변위와 잘 일치하였다.