• Proceedings of the Botanical Society of Korea Conference
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• 1994.09a
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• pp.29-39
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• 1994

Serious issues about the changes in the environmental conditions on earth associated with human activities have arisen, and the interest in these problems has increased. It is urgent to determine how the expansion of terrestrial UV-B radiation due to the stratospheric ozone depletion influences living matters. In this connection, we have been investigating the effects of UV-B radiation on the growth of rice cultivars (Oryza sativa L.). We report here some physiological and genetic aspects of resistance to inhibitory effects of UV-B radiation on growth of rice cultivars as described below. Elevated UV radiation containing large amount of UV-B and a small amount of UV-C inhibited the development of plant height, the photosynthetic rate and the chlorophyll content in rice plants in a phytotron. Similar results were obtained in experiments, in which elevated UV-V radiation. Similar results were obtained in experiments, in which elevated UV-B radiation (transmission down to 290 nm) was applied instead of UV-B radiation containing a small amount of UV-C. The inhibitory effects of UV radiation was alleviated by the elevated CO2 atmospheric environment or by the exposure to the high irradiance visible radiation. The latter suggested the possibility that the resistance to the effects of UV radiation was either due to a lower sensitivity to UV radiation or to a greater ability to recover from the injury caused by UV radiation through the exposure to visible radiation. The examination of cultivar differences in the resistance to UV radiation-caused injuries among 198 rice cultivars belonging to 5 Asian rice ecotypes (aus, aman, boro, bulu and tjeleh) from the Bengal region and Indonesia and to Japanese lowland and upland rice groups showed the following: Various cultivars having different sensitivities to the effects of UV radiation were involved in the same ecotype and the same group, and that the Japanese lowland rice group and the boro ecotype were more resistant. Among Japanese lowland rice cultivars, Sasanishiki (one of the leading varieties in Japan) exhibited more resistance to UV rakiation, while Norin 1 showed less resistance, although these two cultivars are closely related. It was thus indicated that the resistance to the inhibitory effects of UV radiation of rice cultivars is not simply due to the difference in the geographical situation where rice cultuvars are cultivated. Form the genetic analysis of resistance to the inhibitory effects of UV radiation on growth of rice using F2 plants generated by reciprocally crossing Sasanishiki and Norin 1 and F3 lines generated by self-fertilizing F2 plants, it was evident that the resistance to the inhibitory of elebated UV radiation in these rice plants was controlled by recessive polygenes.

• Journal of Gastric Cancer
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• v.23 no.2
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• pp.264-274
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• 2023

Purpose: In this study, polymerase chain reaction (PCR)-based microsatellite instability (MSI) testing was comprehensively analyzed and compared with immunohistochemistry (IHC) for mismatch repair (MMR) protein expression in patients with gastric cancer (GC). Materials and Methods: In 5,676 GC cases, PCR-based MSI testing using five microsatellites (BAT-26, BAT-25, D5S346, D2S123, and D17S250) and IHC for MLH1 were performed. Reevaluation of MSI testing/MLH1 IHC and additional IHC for MSH2, MSH6, and PMS2 were performed in discordant/indeterminate cases. Results: Of the 5,676 cases, microsatellite stable (MSS)/MSI-low and intact MLH1 were observed in 5,082 cases (89.5%), whereas MSI-high (MSI-H) and loss of MLH1 expression were observed in 502 cases (8.8%). We re-evaluated the remaining 92 cases (1.6%) with a discordant/indeterminate status. Re-evaluation showed 1) 37 concordant cases (0.7%) (18 and 19 cases of MSI-H/MMR-deficient (dMMR) and MSS/MMR-proficient (pMMR), respectively), 2) 6 discordant cases (0.1%) (3 cases each of MSI-H/pMMR and MSS/dMMR), 3) 14 MSI indeterminate cases (0.2%) (1 case of dMMR and 13 cases of pMMR), and 4) 35 IHC indeterminate cases (0.6%) (22 and 13 cases of MSI-H and MSS, respectively). Finally, MSI-H or dMMR was observed in 549 cases (9.7%), of which 47 (0.8%) were additionally confirmed as MSI-H or dMMR by reevaluation. Sensitivity was 99.3% for MSI testing and 95.4% for MMR IHC. Conclusions: Considering the low incidence of MSI-H or dMMR, discordant/indeterminate results were occasionally identified in GCs, in which case complementary testing is required. These findings could help improve the accuracy of MSI/MMR testing in daily practice.

• Journal of the Korea Society for Simulation
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• v.18 no.3
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• pp.47-59
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• 2009

Due to the application-specific nature of wireless sensor networks, the sensitivity to such a requirement as data reporting latency may vary depending on the type of applications, thus requiring application-specific algorithm and protocol design paradigms which help us to maximize energy conservation and thus the network lifetime. In this paper, we propose a novel delay-adaptive sensor scheduling scheme for energy-saving data gathering which is based on a two phase clustering (TPC). The ultimate goal is to extend the network lifetime by providing sensors with high adaptability to the application-dependent and time-varying delay requirements. The TPC requests sensors to construct two types of links: direct and relay links. The direct links are used for control and forwarding time critical sensed data. On the other hand, the relay links are used only for data forwarding based on the user delay constraints, thus allowing the sensors to opportunistically use the most energy-saving links and forming a multi-hop path. Simulation results demonstrate that cluster-based delay-adaptive data gathering strategy (CD-DGS) saves a significant amount of energy for dense sensor networks by adapting to the user delay constraints.

• Journal of Korea Society of Industrial Information Systems
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• v.14 no.2
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• pp.23-31
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• 2009

Since 9.11 terrorist attacks against the USA, the new paradigm for "supply chain security" has been established. And at the same time a lot of researches are being made on supply chain security by many foreign companies or research institutes. However, domestically the terms "supply chain security" themselves are not yet familiar, and the paradigm of security are not being used in the logistics, while little researches are being made on them But recently along with development of "ConTracer," a supply chain security technology, which is to be used as the equipment for container cargo transportation safety based on RF1D technology, related researches have begun to be activated. The key issues for the development of equipment for container transportation safety are to obtain both a high recognition rate and enough recognition distance. To this end, this study has tested the ConTracer (433 MHz type and 2.4 GHz type) by using Taguchi Method. According to our test results, in the case of 433 MHz type, it is a little more effective that the reader faces to the front-right side, and in the case of 2.4 GHz, reader direction does not make difference in the view of sensitivity. The test also has proved that it is better that antenna location, as expected, is to be installed on the outside for both types alike.

• Journal of Korean Clinical Nursing Research
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• v.29 no.2
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• pp.198-209
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• 2023

Purpose: The purpose of this study was to develop a Korean Adult Patients Delirium Screening Tool (K-APDS) for those admitted to general wards, and to verify its reliability and validity. Methods: For the development of the tool, 12 items were derived through the results of literature review and focus group interviews with general ward nurses, and the content validity was confirmed by experts. To verify the reliability and validity of the developed tool, 317 adult patients who were admitted to general wards of three tertiary general hospitals from October to November 2022 were evaluated by the attending nurse and data were collected. Results: After factor analysis for construct validity verification, two factors were extracted, which explained 60.1% of the total variance. After the validation of the control group, the difference in the delirium incidence scores calculated using the K-APDS between the delirium group and non-delirium group was very significant (Z=-10.82, p<.001). To verify the criterion validity, K-APDS, Delirium Observation Screening, and Pearson's correlation coefficient were checked and found to be .94 (p<.001). The predictive validity test reported that the sensitivity was 91.1%, specificity was 82.4%, positive predictive value was 52.6%, and negative predictive value was 97.8%. The reliability of K-APDS was found to be high with Cronbach's ⍺=.91. Conclusion: K-APDS can screen for delirium with 2 or more points, excellent validity and reliability have been verified. Therefore, this tool could be applied immediately in the clinical field, and will contribute to the early detection of delirium, enabling rapid interventions.

• Journal of Microbiology and Biotechnology
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• v.33 no.1
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• pp.83-95
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• 2023

These days, bacterial detection methods have some limitations in sensitivity, specificity, and multiple detection. To overcome these, novel detection and identification method is necessary to be developed. Recently, NGS panel method has been suggested to screen, detect, and even identify specific foodborne pathogens in one reaction. In this study, new NGS panel primer sets were developed to target 13 specific virulence factor genes from five types of pathogenic Escherichia coli, Listeria monocytogenes, and Salmonella enterica serovar Typhimurium, respectively. Evaluation of the primer sets using singleplex PCR, crosscheck PCR and multiplex PCR revealed high specificity and selectivity without interference of primers or genomic DNAs. Subsequent NGS panel analysis with six artificially contaminated food samples using those primer sets showed that all target genes were multi-detected in one reaction at 10⁸-10⁵ CFU of target strains. However, a few false-positive results were shown at 10⁶-10⁵ CFU. To validate this NGS panel analysis, three sets of qPCR analyses were independently performed with the same contaminated food samples, showing the similar specificity and selectivity for detection and identification. While this NGS panel still has some issues for detection and identification of specific foodborne pathogens, it has much more advantages, especially multiple detection and identification in one reaction, and it could be improved by further optimized NGS panel primer sets and even by application of a new real-time NGS sequencing technology. Therefore, this study suggests the efficiency and usability of NGS panel for rapid determination of origin strain in various foodborne outbreaks in one reaction.

• Journal of Korean Tunnelling and Underground Space Association
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• v.25 no.1
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• pp.13-26
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• 2023

Recently, as the development of underground spaces has become active due to rapid urbanization and population density, interest in the ground behavior according to the construction of underground spaces is increasing. In large cities with high population density and many buildings, ground subsidence has a great impact on structures and there may be a risk of collapse, so the analysis of ground behavior due to underground construction is essential. Previous studies have been conducted on the subsidence pattern of the surface and the deformation of the tunnel when constructing the tunnel, but analysis has rarely been conducted by using actual topographic information. Therefore, this study analyzed the difference in ground behavior between the actual topography and the flat topography. As a result, it was confirmed that ground settlement occurs at higher elevations, such as in mountainous topography, and when the numerical analysis is performed considering topographical information, the crown settlement of the tunnel is up to about approx. It showed a difference of 10 mm, and it was found that the sensitivity was less in the case of displacement of tunnel wall compared to the crown settlement and ground settlement. The numerical analysis considering the actual GIS-based topographic information presented in this study can be used to obtain more accurate surface subsidence data to understand the behavior of the upper structure due to tunnel excavation.

• Journal of the Korean Geotechnical Society
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• v.25 no.9
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• pp.45-55
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• 2009

The quality of railroad trackbed fills has been controlled by field measurements of density and bearing resistance of plate-load tests. The control measures are compatible with the design procedures whose design parameter is $k_{30}$ for both ordinary-speed railways and high-speed railways. However, one of fatal flaws of the design procedures is that there are no simple laboratory measurement procedures for the design parameters ($k_{30}$ or, $E_{v2}$ and $E_{v2}/E_{v1}$) in design stage. To overcome the defect, the compressional wave velocity was adopted as a control measure, in parallel with the advent of the new design procedure, and its measurement technique was proposed in the preliminary investigation. The key concept of the quality control procedure is that the target value for field compaction control is the compressional wave velocity determined at optimum moisture content using modified compaction test, and direct-arrival method is used for the field measurements during construction, which is simple and reliable enough for practice engineers to access. This direct-arrival method is well-suited for such a shallow and homogeneous fill lift in terms of applicability and cost effectiveness. The sensitivity of direct-arrival test results according to the compaction quality was demonstrated at a test site, and it was concluded that compressional wave velocity can be effectively used as quality control measure. The experimental background far the companion study (Park et al., 2009) was established through field and laboratory measurements of the compressional wave velocity.

• Journal of the Korean Geotechnical Society
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• v.24 no.8
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• pp.125-135
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• 2008

Rigid-soft particle mixtures, which consist of sand and rubber, are investigated for the understanding of the stress-deformation and elastic moduli. Specimens are prepared with various size ratio sr between sand and rubber particles, and different volumetric sand fraction sf. Small strain shear waves are measured under $K_o$-loading condition incorporated with the stress-deformation test by using oedometer cell with bender elements. The stress-deformation and small strain shear wave characteristics of rigid-soft particle mixtures show the transition from a rigid particle behavior regime to a soft particle behavior regime under fixed size ratio. A sudden rise of $\Lambda$ factor and the maximum value of the $\zeta$ exponent in $G_{max}=\;{\Lambda}({\sigma}'_{o}/kPa)^{\zeta}$ are observed at $sf\;{\approx}\;0.4{\sim}0.6$ regardless of the size ratio sf. Transition mixture shows high sensitivity to confining stress. The volume fraction for the minimum porosity may depend on the applied stress level in the rigid-soft particle mixtures because the soft rubber particles easily distort under load. In this experimental study, the size ratio and volumetric sand fraction are the important factors which determine the behavior of rigid and soft particle mixtures.

• Korean Journal of Veterinary Service
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• v.46 no.1
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• pp.15-27
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• 2023

Bordetella (B.) bronchiseptica, Mycoplasma (M.) cynos, and M. canis are the major bacterial pathogens that cause canine infectious respiratory disease complex (CIRDC). In this study, we developed a triplex real-time polymerase chain reaction (tqPCR) assay for the differential detection of these bacteria in a single reaction. The assay specifically amplified three bacterial genes with a detection limit of below 10 copies/reaction. The assay showed high repeatability and reproducibility, with coefficients of intra- and inter-assay variations of less than 1%. The diagnostic results of the assay using 94 clinical samples from household dogs with CIRDC clinical signs, the prevalence of B. bronchiseptica, M. cynos, and M. canis was 22.3%, 18.1%, and 20.2%, respectively, indicating that the diagnostic sensitivity was comparable to those of previously reported qPCR assays. The dual infection rate of B. bronchiseptica and M. cynos, B. bronchiseptica and M. canis, and M. cynos and M. canis was 5.3%, 7.4%, and 3.1%, respectively. Moreover, the triple infection rate of B. bronchiseptica, M. cynos, and M. canis was 2.1%. These results indicate that coinfections with B. bronchiseptica, M. cynos, and M. canis have frequently occurred in the Korean dog population. The newly developed tqPCR assay in the present study will be a useful tool for etiological and epidemiological studies on these three CIRDC-associated bacterial pathogens. The prevalence and coinfection data revealed through this study will contribute to expanding knowledge on the epidemiology of CIRDC in the recent Korean dog population.