• Asian Pacific Journal of Cancer Prevention
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• 제16권1호
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• pp.35-39
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• 2015

Background: Hepatocellular carcinoma (HCC) is one of the most frequent cancers in South East Asian countries including Cambodia, where prevalence of chronic carriers of hepatitis B and C virus (HBV and HCV) is reported to be very high. We reviewed HCC cases admitted to a cancer hospital in Phnom Penh, which is the only one hospital for cancer treatment and care in Cambodia during the study period. Materials and Methods: Information was collected from medical records of 281 cases (210 males and 71 females) diagnosed as primary HCC from 2006 to 2011. Results: The subjects were 7-81 years old with a median age of 53 years. Hypochondriac pain was the most common complained symptom (74%). One third of the cases presented with jaundice. Nearly half had ascites at their first visit. One third had liver cirrhosis. Nearly three fourths of the cases presented with tumor sized more than 50 mm in diameter, and in almost all cases (97.4%) the size was more than 20 mm. Among 209 subjects tested, hepatitis virus carriers were 75.6%; 46.4% for HBV only, 21.5% for HCV only, and 7.7% for both viral infections. Median age of patients with HBV was about ten years younger than those with HCV. Conclusions: This study revealed the characteristics of HCC cases in Cambodia, although there were several limitations. Most HCC cases were infected with HBV and/or HCV, and diagnosed at late stages with complications. This implicated that public health intervention to prevent HBV and HCV infection is of high priority.

• 대한지역사회영양학회지
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• 제7권1호
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• pp.67-75
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• 2002

The purpose of this study was to investigate the difference of body composition, eating habits and dietary intake in three Sasang constitutions. This survey was carried out using anthropometry, a questionnaire about eating habits, and 24-hour recall of dietary intake on 45 male and 29 female students of the fifth grade at C elementary school. The results are summarized as follows: A total of 44.6% of the subjects were Taeumin, 35.1% were Soyangin, and 20.3% were Soeumin. The average weight, WHR, Triceps, Rhrer index and BMI in the Taeumin group were significantly higher than those of the Soeumin and Soyangin groups. The body fat mass (kg) and abdominal fat (%) in the Taeumin group were significantly higher than those of the Soeumin and Soyangin groups. The soft body mass (%) in the Soeumin group was significantly higher than that of the Soeumi and Soyangin groups. The Taeumin’s energy expenditure in physical activities was little high than that of the Soyangin and Soeumin groups, but the Soyangin’s energy expenditure in physical activities per weight was a little higher than that of the Taeumin and Soeumin groups. The calorie and most of the nutrient intake were lower than those of Korean RDA. In the case of males, most nutrient intake, except for fiber, carotene and vitamin C were high in the Taeumin. For females, most nutrient intake, except for calcium and retinol were significantly higher in the Taeumin group. Conclusively, anthropometry characteristics, body composition, energy expenditure in physical activities, eating habits and dietary intake are different among the three Sasang constitutions. This study suggests the possibility of using Sasang consitutions as a basis for providing nutritional education and health guidelines.

• 한국전문물리치료학회지
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• 제26권1호
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• pp.8-18
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• 2019

Background: Numerous studies have used smartphone applications to measure the range of motion in different joints. In addition, studies measuring the active range of motion (AROM) of the craniocervical joint have revealed high reliability. However, the subjects in these studies were all healthy subjects. No study has yet been conducted to measure the inter-rater reliability for the AROM of the craniocervical joint in stroke patients. Objects: The purpose of this study was to investigate the inter-rater reliability of the AROM of the craniocervical joint using a smartphone. Methods: The participants included 21 subjects who had strokes (17 males and 4 females). Two raters evaluated six types of craniocervical AROM, including flexion, extension, lateral flexion to the hemiplegic side, lateral flexion to the non-hemiplegic side, rotation to the hemiplegic side, and rotation to the non-hemiplegic side, using a goniometer and a smartphone to investigate inter-rater reliability. The inter-rater reliability was analyzed by intraclass correlation coefficients (ICC). Results: The inter-rater reliability of the smartphone was good for extension, lateral flexion to the hemiplegic side, lateral flexion to the non-hemiplegic side, and rotation to the hemiplegic side [ICC(2,k)=.86~.88] and excellent for flexion [ICC(2,k)=.95]. The inter-rater reliability for rotation to the non-hemiplegic side was moderate [ICC(2,k)=.72]. Conclusion: These results suggest that the smartphone offers high inter-rater reliability for measurements of the craniocervical AROM in patients with stroke.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5857-5863
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• 2012

Introduction: Mobile phones are in extensive use worldwide and concerns regarding their role in tumor formation were raised. Over the years multiple studies were published in order to investigate this issue using several approaches. The current study looks at secular trends of brain gliomas (low and high grade) incidence and changes in tumor's laterality over 30 years in a population extensively using this technology with a possible correlation to the spread of use of mobile phones. Materials and Methods: All brain gliomas that were diagnosed from 1980-2009 were included and subdivided into two groups - low and high grade. Secular and periodic time trend analyses of incidence rates and changes in laterality were performed. Preferred side of head using mobile phones was assessed with a questionnaire in a sample of adult individuals. Results: A decrease in incidence of low grade giomas (LGG) that correlated with introduction of mobile technology was found from 2.57, 2.34 and 2.79 for every 100,000 in the period 1980 to the end of 1994 to 1.72, 1.82 and 1.57, respectively, over the last three 5-years periods (1995-2009). High-grade glioma incidences increased significantly from 1980-2009 but in the period after mobile phones were introduced (1994-2009) a lower, non significant, rate of increase was observed in males and a lower one (significant) in females. A shift towards left sided tumor location for all adult gliomas combined and separately for LGG and HGG was noted from 1995 onward. The shift was more marked for those who were diagnosed in ages 20-49 (p=0.03). Conclusions: We found a statistically significant decrease in LGG's over 30-years period that correlates with introducing of mobile phones technology and a shift in laterality towards left-sided tumors, the latter occurred in both low and high-grade gliomas.

• Journal of Preventive Medicine and Public Health
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• 제41권1호
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• pp.39-44
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• 2008

Objectives : This study was conducted to investigate the associations of non alcoholic fatty liver with metabolic syndrome and the serum carotenoids. Methods : This study was conducted in a general hospital in South Korea from November, 2004 to August, 2005. The study subjects were 350 sampled persons who were aged from 40 years and older (males : 180, females : 170). They were grouped into the normal, mild and severe groups according to fat accumulation in their livers, as determined by ultrasonography. We analyzed the association between non alcoholic fatty liver and metabolic syndrome by multiple logistic regression analysis and we analyzed the association between non alcoholic fatty liver and the serum carotenoids by a general linear model(ANCOVA). Results : After adjustment for the effect of potential covariates, the prevalence of metabolic syndrome was associated with fat accumulation in the liver (p trend <0.001). If the odds ratio of normal group is 1.00, then that of the mild group is 2.80 (95% C.I=1.17-6.71) and that of the severe group is 7.29 (95% C.I=2.76-19.30). The prevalence of metabolic alterations fitting the criteria of metabolic syndrome, according to the class of fat accumulation in the liver, was significantly increased, except for criteria of high blood pressure, a large waist circumference and low HDL (high density lipoprotein) cholesterol level (p trend <0.001). The level of serum ${\beta}$-carotene was decreased according to the class of fat accumulation in the liver (p trend=0.036), but the levels of serum ${\alpha}$-carotene, lycopene, ${\beta}$-cryptoxanthin and lutein were not decreased. Conclusions : This study shows that non alcoholic fatty liver was associated with metabolic syndrome and with the serum ${\beta}$-carotene level.

• Parasites, Hosts and Diseases
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• 제57권3호
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• pp.303-308
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• 2019

Toxoplasma gondii is an apicomplexan parasite that can cause toxoplasmosis in a wide range of warm-blooded animals including humans. In this study, we analyzed seroprevalence of T. gondii among 467 school children living in the rural areas of Pyin Oo Lwin and Naung Cho, Myanmar. The overall seroprevalence of T. gondii among school children was 23.5%; 22.5% of children were positive for T. gondii IgG, 0.4% of children were positive for T. gondii IgM, and 0.6% of children were positive for both T. gondii IgG and IgM. Geographical factors did not significantly affect the seroprevalence frequency between Pyin Oo Lwin and Naung Cho, Myanmar. No significant difference was found between males (22.2%) and females (25.0%). The overall seroprevalence among school children differed by ages (10 years old [13.6%], 11-12 years old [19.8%], 13-14 years old [24.6%], and 15-16 years old [28.0%]), however, the result was not significant. Polymerase chain reaction analysis for T. gondii B1 gene for IgG-positive and IgM-positive blood samples were negative, indicating no direct evidence of active infection. These results collectively suggest that T. gondii infection among school children in Myanmar was relatively high. Integrated and improved strategies including reinforced education on toxoplasmosis should be implemented to prevent and control T. gondii infection among school children in Myanmar.

• Journal of Gastric Cancer
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• 제4권1호
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• pp.1-6
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• 2004

Purpose: Despite numorous reports on the relationship between the level of carcinoembryonic antigen (CEA) in gall bladder bile and liver metastasis in colorectal cancer, no similar studies have been carried out for gastric carcinomas. We, therefore, undertook the present study to establish the relationship between the gall bladder bile CEA and liver metastasis as well as the post-operative survival rate in gastric carcinoma patients with curative resections. Materials and Methods: In 373 gastric cancer patients (252 males, 121 females, age $21\∼76$ years) operated on at Kosin University Hospital between 1989 1996, the CEA concentration in the gall bladder bile was determined during the operation and the value was related to the rates of post-operative survival and liver metastasis during follow-up period. Results: The overall rate of patient survival decreased gradually with increase in TNM stage. The 13-year postoperative survival rates for stages Ia, Ib, II, IIIa, and IIIb were $95.7\%,\;92.5\%,\;79.9\%,\;50.9\%,\;and\;43.3\$, respectively, and the 10-year survival rate for stage IV was $22.6\%$. The patients with a high ($\geq$10 ng/ml) biliary CEA showed a significantly lower rate of survival than those with a low (<10 ng/ml) biliary CEA. The 13-year cumulative survival rate was $55.4\%$ for the high CEA group and $76.5\%$ for the low CEA group (P<0.01). Also, the patients with a high biliary CEA showed a significantly higher rate ($11.5\%$) of liver metastasis than those with a low biliary CEA ($1.9\%$) (P<0.000). In patients with TNM stages (I and II), the CEA level did not affect the post-operative survival rates ($95.4\%\;and87.7\%$ in the high and low CEA groups, P>0.10), but in those with high TNM stages (III and IV), the survival rate was significantly lower in the high CEA group ($25.9\%$) than in the low CEA group ($57.8\%$) (P<0.05). Conclusion: These result suggest that the gall bladder bile CEA level obtained in an advanced-staged gastric cancer operation may be used in predicting the post-operational survival rate and in sorting out patients with a high risk for cancer recurrence, especially in the liver area.

• Journal of Preventive Medicine and Public Health
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• 제26권4호
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• pp.628-649
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• 1993

국민학생들의 학습부진에 관련된 요인을 조사하여 의학적 예방 및 치료 대책을 고안해 보기 위해, 대구 시내에서 고소득층 밀집지역과 저소득층 밀집지역의 국민학교 1개씩을 선정하고, 각 학교의 2, 4, 6학년 학생 중 학업 성적이 하위 10%에 속하는 학생(학습부진군) 175명과 이에 대한 대조군으로 성적이 상위 5%에 속하는 학생(우수군) 97명을 대상으로 하여 이들에게 시력검사, 청력검사, 신체검사(체중, 신장, 두위)를 한 후, 고대 Stanford-Binet test를 이용한 지능검사와 TAI-K로 시험불안반응검사를 하고 발달소아학 전문의사가 신경학적 검진을 하였다. 아동의 어머니에게는 가정 환경, 어머니의 출산력, 아동의 출생 전후 및 과거력에서 의학적 특이사항, 그리고 행동양상에 관해 설문조사하고, 담임 선생에게 설문지를 통해 학교에서의 행동양상을 조사하였다. 아동의 두발을 적당량 채취하여 두발중 납, 카드뮴, 아연의 함량을 원자흡광분광광도계로 분석하였다. 학습부진과 각 요인과의 단순상관 관계분석에서 통계적으로 유의한 요인들을 이용한 다중지수형 회귀분석 (multiple logistic regression analysis)을 하여 학습부진의 관련요인을 찾았다. 단순분석에서 학습부진과 유의한 관련성이 있는 것은 남아인 경우, 출산순위가 높은 경우, 결손가정인 경우, 부모의 학력이 낮거나 직업이 노동직인 경우, 아동의 체중, 신장 및 두위가 작은 경우, 시력장애가 있는 경우, 지능지수가 낮은 경우, 시험불안반응점수가 높은 경우, 과잉활동성 아동인 경우로 나타났다. 다중지수형 회귀분석결과 학습부진과 관련되는 요인은 아동의 높은 출산순위 (odds ratio=2.06), 남아인 경우(odds ratio=5.91), 결손가정(odds ratio=9.29), 신장이 표준치-1 표준편차보다 작은 경우(odds ratio=11.12), 높은 시험불안점수(odds ratio=1.07), 과잉활동성 장애아동(odds ratio=9.67), 그리고 지능지수(odds ratio=0.85)였다. 두발중 중금속 함량의 분석결과 모두 학습부진과 뚜렷한 관련성이 없었으며, 납과 카드뮴의 함량은 학습부진군과 우수군 모두 남아가 여아에 비해 높았으며, 남은 학년과 역상관 관계(p<0.05)를, 아연은 정상관 관계(p<0.05)를 나타내었다. 학습부진과 유의한 관련성이 있는 요인들 중 조정가능한 것은 출산순위, 신장, 과잉활동성 장애 등으로, 가족계획을 통해 알맞은 수의 자녀를 갖도록 하고, 영유아기에서부터 사춘기에 이르기까지 적절한 영양공급을 하며, 과잉활동성 아동을 조기에 발견하여 의사의 진단을 받아 치료를 받도록 하는 것이 학습부진을 예방 및 해결하는데 도움이 될 것이다. 또한 부모와 담임 선생이 학습부진아에게 본인의 지적능력 이상의 기대나 학습의 강요로 불안을 조장하지 않도록 해야 할 것이다.

• 영재교육연구
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• 제24권1호
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• pp.1-16
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• 2014

본 연구에서는 고등학생의 학업성취 정도를 토대로 세 집단(영재, 고성취 평재, 저성취 평재)간 유능감, 학업동기 및 학습전략에 차이를 보이는지, 그리고 이들 변인들 중 어떠한 특성이 유능감을 유의미하게 예측해주는지를 탐색하고자 하였다. 본 연구의 표집대상은 경기도에 소재한 영재학교 1개교, 고성취 평재 집단과 저성취 평재 집단으로 분류된 일반 고등학교 2개교에 재학 중인 학생 총 600명이었으며, 이들 중 회수된 489명(회수율 81.5%)을 최종 분석대상으로 하였다. 이들의 평균 나이는 만 17.20세(표준편차= 3.38)였다. 학생들의 유능감과 학업동기(내재적 동기, 외재적 동기, 무동기), 학습전략(초인지, 자기점검, 전략형성)을 측정한 결과, 유능감은 내재적 외재적 학업동기의 모든 하위요인 및 학습전략과 유의한 정적 상관을 보인 반면, 학업동기 중 '무동기' 요인과는 유의한 부적 상관을 보였다. 또한, 성취 수준에 따른 학생들의 유능감, 학업동기, 학습전략이 유의한 차이를 보이는지 살펴보기 위해 다변량 분석을 수행한 결과 '투사된 외재 학업동기'를 제외한 모든 변인에서 성취 수준에 따른 유의한 차이가 있는 것으로 나타났다. 본 연구결과를 토대로 볼 때, 학생들의 학업 동기를 향상시키고, 다양하고 적극적인 학습 전략을 사용하여 학업 성취를 높이기 위해서는 학생들의 유능감을 증진시키는 것이 도움이 될 것으로 판단된다. 따라서 본 연구결과는 성취수준이 뛰어난 영재학생은 물론 성취수준이 높은 고성취 평재와 성취수준이 낮은 저성취 평재 학생들의 유능감 향상방안을 강구하는 데 기초자료로 활용될 수 있을 것으로 기대된다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3447-3453
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• 2016

Background: Gall bladder cancer (GBC) is highly fatal disease with poor prognosis, with a 5 year survival rate of <10%. It is relatively rare cancer worldwide; however it is the sixth cancer and second most common gastrointestinal tract cancer in Nepalese women. The study focused on associations of certain demographic, lifestyle, dietary, and reproductive factors with gall bladder cancer. Materials and Methods: We conducted a hospital-based matched case control study on newly diagnosed cases of primary GBC at BP Koirala Institute of Health Sciences and BP Koirala Memorial Cancer Hospital. Controls were healthy non-GBC relatives of cancer patients, matched for age, sex and marital status (in case of females) with cases at a ratio of 1:2. Data were collected between April 2012-April 2013 by semi structured interview from both cases and controls. Analyses were carried out with SPSS. Conditional logistic regression was used to find odds ratios and 95% confidence intervals for bivariate and multivariate analysis. Results: A total of 50 cases and 100 controls were enrolled in this study. On bivariate analysis, factors found to be significantly associated with gallbladder cancer were illiteracy (OR=3.29, CI=1.06-10.2), history of gallstone disease (OR=27.6, CI=6.57, 115.6), current smoker (OR=2.42, CI=1.005-5.86), early menarche <13 years (OR=2.64, CI=1.09-6.44), high parity more than 3 (OR=3.12, CI=1.25,7.72), and use of mustard oil (OR=3.63, CI=1.40, 9.40). A significant protective effect was seen with high consumption of fruits at least once a week (OR=0.101, CI=0.03-0.35). On multivariate analysis, history of gallstone disease, early menarche, current smoker and high consumption of fruits persisted as significant factors. Conclusions: History of gallstone disease, cigarette smoking and early menarche were associated with increased risk of gallbladder cancer while high consumption of fruits was found to have a protective effect.