• 제목/요약/키워드: High risk factor

검색결과 1,388건 처리시간 0.028초

소비자의 인터넷쇼핑 구매경험과 기술준비성이 인터넷 의류쇼핑시 위험지각과 만족도에 미치는 영향 (The Influence of Consumers' Purchase Experience and Technology Readiness on Risk Perception and Satisfaction in Internet Clothing Shopping)

  • 홍금희
    • 한국의류산업학회지
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    • 제6권1호
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    • pp.93-101
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    • 2004
  • The purpose of this study is to examine consumers' risk perception in internet clothing shopping and its relation with technology readiness and the frequency of purchase. Thereafter, this study examines how consumers' risk perception affect service quality and satisfaction at the apparel shopping sites. An on-line survey was made to collect data, and the replies from 785 people, who had an experience of apparel shopping on line, were used in data analysis. From factor analyses, risk perception comprised 3 factors of product related risk, delivery related risk, and security related risk, and technology readiness comprised 4 factors of optimism, innovativeness, discomfort, and insecurity. Based on cluster analysis, consumers were classified into 3 types in terms of the internet risk perception: low risk group, medium risk group, and high risk group. From path analysis, risk perception was decreased with high frequency of purchase and low discomfort and insecurity of technology readiness, and risk perception and service quality had an influence on consumers' satisfaction with the shopping sites.

Increased Wall Enhancement Extent Representing Higher Rupture Risk of Unruptured Intracranial Aneurysms

  • Jiang, Yeqing;Xu, Feng;Huang, Lei;Lu, Gang;Ge, Liang;Wan, Hailin;Geng, Daoying;Zhang, Xiaolong
    • Journal of Korean Neurosurgical Society
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    • 제64권2호
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    • pp.189-197
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    • 2021
  • Objective : This study aims to investigate the relationship between aneurysm wall enhancement and clinical rupture risks based on the magnetic resonance vessel wall imaging (MR-VWI) quantitative methods. Methods : One hundred and eight patients with 127 unruptured aneurysms were prospectively enrolled from Feburary 2016 to October 2017. Aneurysms were divided into high risk (≥10) and intermediate-low risk group (<10) according to the PHASES (Population, Hypertension, Age, Size of aneurysm, Earlier SAH history from another aneurysm, Site of aneurysm) scores. Clinical risk factors, aneurysm morphology, and wall enhancement index (WEI) calculated using 3D MR-VWI were analyzed and compared. Results : In comparison of high-risk and intermediated-low risk groups, univariate analysis showed that neck width (4.5±3.3 mm vs. 3.4±1.7 mm, p=0.002), the presence of wall enhancement (100.0% vs. 62.9%, p<0.001), and WEI (1.6±0.6 vs. 0.8±0.8, p<0.001) were significantly associated with high rupture risk. Multivariate regression analysis revealed that WEI was the most important factor in predicting high rupture risk (odds ratio, 2.6; 95% confidence interval, 1.4-4.9; p=0.002). The receiver operating characteristic (ROC) curve analysis can efficiently differentiate higher risk aneurysms (area under the curve, 0.780; p<0.001) which have a reliable WEI cutoff value (1.04; sensitivity, 0.833; specificity, 0.67) predictive of high rupture risk. Conclusion : Aneurysms with higher rupture risk based on PHASES score demonstrate increased neck width, wall enhancement, and the enhancement intensity. Higher WEI in unruptured aneurysms has a predictive value for increased rupture risk.

고등학교 청소년의 건강위험행위에 영향을 미치는 요인 (Factors Influencing Health Risk Behavior in High School Students)

  • 최진;김미예
    • Child Health Nursing Research
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    • 제15권2호
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    • pp.182-189
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    • 2009
  • Purpose: The purpose of this study was to identify the factors influencing health risk behavior in high school students. Methods: The subjects were 512 students from 4 high schools in 3 cities. The questionnaire measured the level of self-esteem, self-efficacy, internal locus of control and health risk behaviors. The data were analyzed using descriptive statistics, t-test, ANOVA, Scheffe test, Pearson's correlation coefficient and stepwise multiple regression analysis. Results: There were significant differences in the health risk behaviors according to sex, a classification of the school, whether or not smoking of mother, whether or not live alone, level of harmonious family, level of satisfying school-life and three variables of them were significant differences by Scheffe test. There was a significant positive correlation between sub-dimension of health risk behaviors and the self-efficacy, self-esteem, internal locus of control were negative correlation with health risk behaviors. The most important influential factor of the health risk behaviors was the self-efficacy. Conclusion: From the studies reviewed, improving the self-efficacy, self-esteem, internal locus of control and the general social environment of students will probably be the most effective strategies for primary prevention of health risk behaviors.

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Triglyceride-Rich Lipoproteins and Novel Targets for Anti-atherosclerotic Therapy

  • Reiner, Zeljko
    • Korean Circulation Journal
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    • 제48권12호
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    • pp.1097-1119
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    • 2018
  • Although elevated serum low-density lipoprotein-cholesterol (LDL-C) is without any doubts accepted as an important risk factor for cardiovascular disease (CVD), the role of elevated triglycerides (TGs)-rich lipoproteins as an independent risk factor has until recently been quite controversial. Recent data strongly suggest that elevated TG-rich lipoproteins are an independent risk factor for CVD and that therapeutic targeting of them could possibly provide further benefit in reducing CVD morbidity, events and mortality, apart from LDL-C lowering. Today elevated TGs are treated with lifestyle interventions, and with fibrates which could be combined with omega-3 fatty acids. There are also some new drugs. Volanesorsen, is an antisense oligonucleotid that inhibits the production of the Apo C-III which is crucial in regulating TGs metabolism because it inhibits lipoprotein lipase (LPL) and hepatic lipase activity but also hepatic uptake of TGs-rich particles. Evinacumab is a monoclonal antibody against angiopoietin-like protein 3 (ANGPTL3) and it seems that it can substantially lower elevated TGs levels because ANGPTL3 also regulates TGs metabolism. Pemafibrate is a selective peroxisome proliferator-activated receptor alpha modulator which also decreases TGs, and improves other lipid parameters. It seems that it also has some other possible antiatherogenic effects. Alipogene tiparvovec is a nonreplicating adeno-associated viral vector that delivers copies of the LPL gene to muscle tissue which accelerates the clearance of TG-rich lipoproteins thus decreasing extremely high TGs levels. Pradigastat is a novel diacylglycerol acyltransferase 1 inhibitor which substantially reduces extremely high TGs levels and appears to be promising in treatment of the rare familial chylomicronemia syndrome.

해상교통환경 위험요소의 상대적 중요도를 고려한 목포항 및 진입수로의 위험도 평가 (Evaluation on Risk at the Port of Mokpo and its Approaches based on Relative Importance of Risk Factors for Marine Traffic Environment)

  • 이홍훈;김철승
    • 해양환경안전학회지
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    • 제19권4호
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    • pp.375-381
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    • 2013
  • 해상교통환경의 위험도를 평가하기 위해서는 위험도를 구성하고 있는 위험요소들을 명확히 식별하고, 식별된 위험요소들을 평가할 수 있는 기준을 마련하여야 한다. 한편 이러한 각 위험요소들의 위험수준의 합으로 전체 위험도를 나타낼 수 있으므로, 각 위험요소가 전체 위험도에서 차지하는 비중인 상대적 중요도가 분석되어야 한다. 본 연구는 선행연구에서 국내 외 해상교통환경 위험도 평가모델들의 검토를 통하여 제시된 국내 해상교통환경의 위험도를 구성하는 20가지 위험요소와 평가기준 및 해상교통전문가 집단에 의한 설문조사를 통하여 계층분석적 의사결정법으로 분석한 각 위험요소의 상대적 중요도를 바탕으로, 국내 목포항 및 그 진입수로에 대한 해상교통환경의 위험도를 평가하였다. 목포항 및 그 진입수로는 비교평가를 위하여 총 4개의 해역으로 구분하여 분석하였으며, 분석결과 위험요소 해수운동 복잡성 예인선 도선사 선박교통관제 등에서 위험수준이 높게 나타난 정등해 항로의 위험도가 가장 높게 평가되었다. 이러한 평가결과는 동일한 해역에서 본 연구와는 다른 정성적 혹은 정량적 위험도 분석기법을 이용한 연구들의 평가결과와 대체로 일치하였다.

중국 20대 소비자들의 인터넷 쇼핑 위험지각이 구전(e-WOM)에 미치는 영향 (The Effects of Risk Perception on e-WOM in Internet Shopping of Chinese Consumers in Their 20s)

  • 서초;박혜선
    • 한국의류학회지
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    • 제38권5호
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    • pp.690-704
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    • 2014
  • This study examined the risk perception in internet shopping by Chinese and analyzed the effects of risk perception on internet word-of-mouth acceptance and transmission. This analysis was conducted with data collected from 373 Chinese individuals in their 20s. Data were analyzed with factorial analysis, cluster analysis, ANOVA, multiple regression analysis, Chi-square test, and Cronbach's ${\alpha}$ using SPSS 18.0. The results were: 1) The factor analysis of risk perception extracted four factors: fashion/social psychological risk, product risk, transaction risk, and economic risk. The cluster analysis classified them into: Group with low-risk, Group with high-risk, Group with economic risk, and Group with medium-risk. 2) Group with high-risk and Group with economic risk had a higher word-of-mouth acceptance than other groups. The Group with a high-risk had more word-of-mouth transmission than other groups. 3) It was found that when word-of-mouth was accepted, the factual information about fashion products (size and material) was most referred to, and that the overall evaluation of satisfaction and dissatisfaction was most conveyed when word-of-mouth was conveyed. 4) Internet word-of-mouth acceptance was affected by product risk, economic risk, and transaction risk. Internet word-of-mouth transmission was affected by economic risk, and fashion/social psychological risk, product risk, and transaction risk.

비스테로이드소염제로 인한 궤양 합병증 예방을 위한 비스테로이드소염제 사용 현황 및 적절성 평가 (Evaluation of NSAID Usage and Appropriateness for Prevention of NSAID-Related Ulcer Complications)

  • 조정원;이은숙;신완균
    • 한국임상약학회지
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    • 제22권3호
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    • pp.211-219
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    • 2012
  • Nonsteroidal antiinflammatory drugs (NSAIDs) are used in the treatment of extensive diseases related to various symptoms; inflammation, pain and fever. NSAIDs work by blocking prostaglandin synthesis, but adverse drug events (ADEs) have been increasing dramatically such as gastrointestinal bleeding, perforation and stenosis, a kind of serious ADEs. Therefore, NSAID-related ulcer complication guidelines have been announced containing various risk factors and symptoms. Thus, this study aims to evaluate of NSAID usage and appropriateness for prevention of NSAID-related ulcer complication based on American journal of gastroenterology (AJG) guideline 2009. Further, the study suggests Korean guideline for prevention of NSAID-related ulcer compared to AJG guideline. For this study, data was collected through electronic medical record (EMR) at Seoul national university of Bundang hospital. The primary end point was a composite of NSAID-related ulcer risk factor, types of NSAIDs, co-prescribed NSAID ulcer prevention drugs and NSAID-related ulcer after taking NSAID. The risk factors include over 65 years, high dose NSAID, previous ulcer history and taking drugs (e.g. aspirin, anticoagulant and steroid) causing ulcer. If a patient has 3 or 4 factors, that patient was classified high risk group. And if 1 or 2 factors that patient was classified moderate risk group. The patient who has no risk factor was in low risk group. I studied 8,120 patients who received NSAID from 1 January 2009 to 31 December 2009. High risk group was 16(0.2%), moderate risk group was 4,364(53.7%), and low risk group was 3,740(46.1%). The results show that high risk group should be prescribed COX-2 inhibitors with ulcer prevention drugs, and moderate or low risk group need traditional NSAIDs with ulcer prevention drugs. This may be different with 2009 AJG guideline because AJG guideline suggested taking COX-2 inhibitor alone in moderate group or taking traditional NSAID alone in low risk group could get higher ulcer complication. The results indicated that choosing preventive drug is important in case that how many risk factors the patients have. The proper drugs would be helpful for safe and effective NSAID usage in each patient group.

농촌지역 주민의 심혈관 질환 위험요인 평가 (An Evaluation Study on the Cardiovascular Risk Factors in a Rural Adult Population)

  • 나백주;박경수;임정수;선병환;남해성;손석준
    • 농촌의학ㆍ지역보건
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    • 제23권2호
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    • pp.193-204
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    • 1998
  • Cardiovascular diseases are the leading cause of death and disability in Korea. Their risk factors can be classified as either modifiable or nonmodifiable and among modifiable factors are high bood pressure, elevated blood cholesterol, obesity and cigarette smoking. The purpose of this study was to evaluate the risk factors for the cardiovascular diseases in a rural community and to get basic data for the development of a community-based rick reduction intervention program. Evaluation involved population-based, cross-sectional samples of adult residents in a rurual community. We measured blood pressure, body fat percent by bioelectric impedance fatness analyzer and serum cholesterol and interviewed adult residents over 20-year-old age. Blood pressure was checked twice and hypertension was classified by the sixth report of the Joint National Committee on Detection. Evaluation, and Treatment of High Blood Pressure. The Cutpoints for high blood cholesterol was used National Cholesterol Treatment Guidelines and those for obesity was 25% in male. 30% in female. The results were as follows: 1. Prevalence of definitive hypertension was 59.7% in males and 54.4% in female. 2. Prevalence of hypercholesterolemia was 14.3% in male and 18.2% in female. 3. Prevalence of obese was 10.7% in male and 41.1% in female. 4. Among definitive hypertension, hypercholesterolemia, and obesity 52.1% possessed one risk factor, 12.6% two risk factors and 2.5% three risk factors in males. In females 41.4% possessed one risk factor and 27.6%. 5.7% respectively. 5. The smoking rate was 65.8% in males and 5.2% in females. Our results are used effectively for the community-based intervention towards cardiovascukr diseases risk reduction. However, because of limitations in our study design, further datas are needed including other risk factors and in-person clinical datas.

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The role of oral physicians in predicting the risk of obstructive sleep apnea: A case-control study

  • Lavanya, Reddy;Babu, Dara Balaji Gandhi;Chavva, Sunandha;Boringi, Mamatha;Waghray, Shefali;Yeladandi, Mounica
    • Imaging Science in Dentistry
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    • 제46권3호
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    • pp.167-171
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    • 2016
  • Purpose: Obstructive sleep apnea (OSA) is a common medical disorder with serious complications if untreated. Dentists play a vital role in the early diagnosis of this condition, thereby improving patients' prognoses. The purpose of this study was to identify patients with a high risk of OSA using simple cephalometric measurements in patients receiving routine dental care. Materials and Methods: The present study was conducted on 206 patients divided into a high-risk group and a control group after answering the Berlin questionnaire. Cephalometric analysis of a digital cephalogram was performed to measure the upper airway diameter (UAD) and mandibular-to-hyoid bone distance (MP-H) by 2 observers at 2 different times. Results: Among 206 patients, 93 (45%) were included in the high-risk group and 113 (55%) were in the control group. No significant difference was present between the groups with regard to gender, and the patients ranged in age from 18 to 65 years. The UAD measurements in the high-risk group were significantly lower than in the control group, and the MP-H measurements were significantly higher in the high-risk group than in the control group. The UAD was lower in middle-aged patients in both groups. Conclusion: Our study found that the UAD was lower in individuals with a high risk of OSA. Also, we found that middle-aged individuals of both genders were more likely to develop OSA. Dentists play a vital role in diagnosing patients at a high risk for OSA via thorough clinical examinations, risk factor analyses, and simple cephalometric analyses.

Seropositivity of Toxoplasmosis in Pregnant Women by ELISA at Minia University Hospital, Egypt

  • Kamal, Amany M.;Ahmed, Azza K.;Abdellatif, Manal Z.M.;Tawfik, Mohamed;Hassan, Ebtesam E.
    • Parasites, Hosts and Diseases
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    • 제53권5호
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    • pp.605-610
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    • 2015
  • Toxoplasmosis is considered as an important risk factor for bad obstetric history (BOH) and one of the major causes of congenitally acquired infections. The present study aimed to estimate the seropositivity of T. gondii infection and associated risk factors among the attendees of high risk pregnancy and low risk antenatal care clinic of Minia Maternity and Pediatric University Hospital, Minia, Egypt. The study was carried out from April 2013 to April 2014 through 2 phases, the first phase was case-control study, and the second phase was follow-up with intervention. A total of 120 high risk pregnant and 120 normal pregnant females were submitted to clinical examinations, serological screening for anti-Toxoplasma IgM and IgG antibodies by ELISA, and an interview questionnaire. Seropositive cases were subjected to spiramycin course treatment. The results showed that the seroprevalence of toxoplasmosis in high-risk pregnancy group was 50.8%, which was significantly different from that of normal pregnancy group (P<0.05). Analysis of seropositive women in relation to BOH showed that abortion was the commonest form of the pregnancy wastage (56.5%). The high prevalence of T. gondii seropositive cases was observed in the age group of 21-30 years. Post-delivery adverse outcome was observed in 80.3% of high-risk pregnancy group compared to 20% of normal pregnancy group. There was a statistically significant relationship between seropositivity and living in rural area, low socioeconomic level, and undercooked meat consumption (P<0.05). Serological screening for anti-Toxoplasma antibodies should be routine tests especially among high-risk pregnant women.