• The Journal of the Korea Contents Association
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• v.13 no.8
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• pp.308-313
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• 2013

Among 179 specimen diagnosed with ASCUS but did not go through biopsy or other tests, 26 cases (14.52%) showed positivity in HPV Hybrid Capture II Test. There were 25 cases of HPV high risk factor(+), marking 13.96%, and 3 cases of low risk factor(+) at 1.67%. According to cytology manifestation, patients with over LSIL can increase their complete recovery rate with continuous tests, but most patients diagnosed ASCUS do not go through any tests at all. It is considered that in order to prevent and start early treatment on cervical cancer, the HPV Hybrid Capture II Test must be enforced to patients diagnosed with ASCUS. Negative patients should go through routine screening, and positive patients should receive treatment after colposcopy.

• Journal of Families and Better Life
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• v.27 no.2
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• pp.203-211
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• 2009

This study was conducted to evaluate a forecast model designed to describe a vocational high school for runaway students. The study included 2000 adolescents from the KEEP(Korean Education and Employment Panel). A Data mining decision tree model revealed that: (1) Suicide ideation was a risk factor for running away among smokers. (2) High self-evaluation was a risk factor for running away among individuals that smoked and had no suicide ideation. (3) Drinking was predicted as a risk factor for no smokers, while family life dissatisfaction was predicted as a risk factor among non-smokers that drank. (4) Negative relationship with mother was predicted as a risk factor among non-drinking non-smoking.

• Proceedings of the Korea Contents Association Conference
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• 2012.05a
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• pp.175-176
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• 2012

세포선별검사에서 ASCUS로 진단된 검체 중 F-UP이 진행되지 않은 검체 179건을 대상으로 HPV High risk factor, Low risk factor를 확인하기 위해서 Hybrid Capture II Test를 하였다. 결과 High risk factor 양성 및 Low risk factor 양성은 전체 179 cases 중 25 cases로 나타났으며, 전체 검체 중 약 15%에 해당되었다. 또한 전체 15%의 양성검체 중 High risk factor 양성은 87%에 해당되는 것을 확인하였다. 결론적으로 효과적인 검진 체계를 갖춘 나라에서도 자궁경부암의 예방이 완전히 해결되지 않고 있는 문제점이 있는 여건을 고려해 볼 때 추적 관찰이 용이하지 않은 경우를 대비해 자궁경부암으로 진행될 수 있는 precancerous lesion의 원인 인자인 HPV 존재 유무를 세포선별검사와 HPV Hybrid Capture II Test를 동시에 시행하는 것이 효과적이라고 사료된다.

• Korean Journal of Clinical Oncology
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• v.14 no.2
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• pp.116-119
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• 2018

Purpose: This study assessed the effect of chemotherapy over stage II colon cancer in terms of presence of high-risk factors. Methods: Data were retrospectively reviewed for 364 patients with stage II colon cancer who underwent curative surgery between January 2007 and December 2012. High-risk factors of stage II colon cancer were examined, and the overall survival (OS) rates were analyzed. Survival benefit of adjuvant chemotherapy was also analyzed. Results: One hundred and fifteen cases had exclusively single high-risk factor and 194 cases were negative for high-risk factors. Postoperative chemotherapy was performed in 262 of 364 patients (72.0%). The 5-year OS was 79.4% and 86.6% for patients without adjuvant chemotherapy and those with chemotherapy, respectively. The 5-year OS was 88.2% and 83.3% for patients having exclusively single high-risk factor with adjuvant chemotherapy and those without chemotherapy, respectively. Conclusion: Adjuvant chemotherapy for patients with stage II colon cancer having exclusively single high-risk factor could be omitted, weighing up the survival benefit and side effect of chemotherapy.

• Journal of Distribution Science
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• v.11 no.10
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• pp.55-62
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• 2013

Purpose - The purpose of this study is to suggest a risk factor that significantly explains foreign currency risk premia. In recent years, some studies have found that the performance of the simultaneous consumption risk model improves considerably when tested on foreign currency portfolios, which are constructed based on the international interest rates differentials. However, this paper focuses on the long-run consumption risk factor. In our empirical research, we found that the real excess returns of high interest rate currency portfolios depreciate on average, when the future American long-run consumption growth rate appears low. This makes the high interest rate currency portfolios have relatively high risk premia. Meanwhile, the real excess returns of low interest rate currency portfolios appreciate on average, under the same conditions, which results in relatively low risk premia for these portfolios. Therefore, this long-run consumption risk factor might explain why low interest rate currencies do not appreciate as much as the interest rate differential, and why high interest rate currencies do not depreciate as much as the interest rate differential. Research design, data, methodology - In our explanation, we provide new evidence on the success of long-run consumption risks in currency risk premia by focusing on the long-run consumption risks borne by American representative investors. To uncover the hidden link between exchange rates and long-run consumption growth, we set the eight currency portfolios as our basic assets, which have been built based on the foreign interest rates of eighty countries. As these eight currency portfolios are rebalanced every year, the first group always contains the lowest interest rate currencies, and the last group contains the highest interest rate currencies. Against these basic eight currency portfolios, we estimate the long-run consumption risk model. We use recursive utility framework and the stochastic discount factor that depends on the present value of expected future consumption growth rates. We find that our model is optimized in the two-year period of constructing the durable consumption expectation factor. Our main results surprisingly surpass the performance of the existing benchmark simultaneous consumption model in terms of R², relatively risk aversion coefficient γ, and p-value of J-test. Results - The performance of our model is superior. R², relatively risk aversion coefficient γ, and p-value of J-test of our long-run durable consumption model are 90%, 93%, and 65.5%, respectively, while those of EZ-DCAPM are 87%, 113%, and 62.8%, respectively. Thus, we can speculate that the risk premia in foreign currency markets have been determined by the long-run consumption risk. Conclusions - The aggregate long-run consumption growth risk explains a large part of the average change in the real excess returns of foreign currency portfolios. The real excess returns of high interest rate currency portfolios depreciate on average when American long-run consumption growth rate is low, and the real excess returns of low interest rate currency portfolios appreciate under the same conditions. Thus, the low interest rate currency portfolios allow investors to hedge against aggregate long-run consumption growth risk.

• Journal of the Korean Home Economics Association
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• v.47 no.5
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• pp.67-77
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• 2009

This study examined risk factors and protective factors in high school students’ suicidal ideation. Participants were 2000 adolescents from the KEEP(Korean Education and Employment Panel). Data mining decision tree model revealed that: (1) Irrespective of sex, the most important predictor was father-adolescent relationship. (2) Positive mother-adolescent relationship was predicted as protective factor in condition of negative father-adolescent relationship. (3) Family activities was predicted as risk factor in condition of negative mother-adolescent relationship under the circumstances with negative father-adolescent relationship. (4) Low self-evaluation was predicted as risk factor in condition of serious agony about personality under the circumstances with positive father-adolescent relationship.

• Journal of Genetic Medicine
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• v.7 no.1
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• pp.1-8
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• 2010

Hemophilia A is a sex-linked recessive coagulation disorder associated with diverse mutations of the factor VIII gene and a variety of phenotypes. The type of mutation involved dictates the activity of factor VIII, and in turn the severity of bleeding episodes and development of alloantibodies against factor VIII (inhibitors). Missense mutations are the most common genetic risk factors for hemophilia A, especially mild to moderate cases, but carry the lowest risk for inhibitor development. On the other hand, intron 22 inversion is the most common mutation associated with severe hemophilia A and is associated with high risk of inhibitor formation. Large deletions and nonsense mutations are also associated with high risk of inhibitor development. Additional mutations associated with hemophilia A include frameshift and splice site mutations. It is therefore valuable to assess the mutational backgrounds of hemophilia A patients in order to to interpret their symptoms and manage their health problems.

• Journal of Preventive Medicine and Public Health
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• v.32 no.4
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• pp.513-525
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• 1999

Objectives : High-normal blood pressure' is a factor influencing decision to initiate targeted intensive intervention strategy in westernized populations. JNC-VI offered the vigorous lifestyle modification for persons with 'high-normal blood pressure', who could be early detected. As a hypertension seems to be the result of multiple genetic factors operating in concert with associated environmental factors, it will be necessary to identify the high-normal blood pressure as a risk factor of hypertension for applying primary prevention strategy in Korean people. Methods : Although cohort study design might be adequate to recruit incidence cases, to keep time sequence of events, and to prevent information bias, nested case-control study was chosen for avoiding measurement errors because hypertension is a benign disease. Source population was the 'Seoul Cohort' participants and follow-up was done by using Korea Medical Insurance Corporation's database on the utilization of health services from 1 Jan93 to 30Jun97. Incidence cases were ascertained through the chart review, telephone contacts, and direct blood pressure measurements. Controls included the pairing of 4 individuals to each case on the basis of age. Results : As 75% of 247 incident cases had high-normal blood pressure, the crude odds ratio for hypertension was 2.04 (95% CI 1.47-2.83). Another statistically significant risk factors of hypertension were body mass index, dietary fiber, alcohol consumption, weekly activity and history of quitting smoking. The multivariate odds ratio of high-normal blood pressure adjusted for all risk factors was 1.84 (95% CI 1.31-2.56). Among high-normal blood pressure group, body mass index, weekly ethanol amounts, weekly physical activity, and dietary fiber except history of quitting smoking were still risk factors of hypertension. Conclusion : 'High-normal blood pressure' is a risk factor for hypertension in Korean middle-aged men, which represents that the vigorous lifestyle modification for persons with 'high-normal blood pressure' is need.

• The Korean Journal of Health Service Management
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• v.13 no.4
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• pp.243-252
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• 2019

Objectives: This study aimed to determine whether the self-rated health (SRH) could be a risk factor for compulsion. Methods: Data related with compulsion and SRH information were collected from 532 young adults aged over 20 years in South Korea. The distribution of the high and low SRH groups was analyzed using the chi-square test, whereas difference in quality of life (QoL) was analyzed using the t-test. Logistic regression was used to analyze the odds ratio (OR). Results: In the high and low-SRH groups, 44 (28.8%) and 23 (31.5%) men and 24 (10.4%) and 21 (27.6%) women, respectively, were at risk for compulsion (p<.001). For women, the compulsion scores of the low and high-SRH groups, respectively, were 15.8±9.53 and 9.9±8.47 (t=5.071, p<.001). The low-SRH group had higher ORs compared with the high-SRH group among women (OR 3.277, 95% confidence interval 1.699 - 6.321, p<.001) in the original model, and this phenomenon was significant even after adjusting for age and residence type. Conclusions: Low SRH may be a risk factor for compulsion. Further research for improving SRH by developing preventive measures against compulsion is necessary.

• Asian Oncology Nursing
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• v.8 no.2
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• pp.120-127
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• 2008

Purpose: The purpose of this study was secondary analysis to explore about risk factors with breast cancer on a basis of primary literature. Methods: This study was searched articles by using CINAHL, MEDLINE, Riss4u, Internet website regarding breast cancer. This study searched for the journal published in Korea and foreign countries from 2000 to 2008, about risk factors of breast cancer. This study was reviewed 42 articles (5 experimental study, 35 survey, 1 qualitative study, 1 report) suitable for the research objectives. Results: Magnitude of risk breast cancer (++) was age, geographic region, family history, mutations in BRCA1, BRCA2 genes and in other penetrance genes, radiation, history of benign breast disease, late age of menopause, early age of menarch, nulliparity and older age at first birth, high mammographic breast density, high insulin-like growth factor 1 level. Magnitude of risk factor (+) was hormone replacement therapy, oral contraceptives use, obesity, tall stature, alcohol consumption, high prolactin level, high saturated fat and well-done meat intake, polymorphisms in low penetrance gene, high socioeconomic status. Conclusion: A breast cancer screening protocol according to magnitude of risk factors is needed for disease prevention. The nurses need to educate and counsel women with risk factors of breast cancer.