• Title/Summary/Keyword: High pressure sodium

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Effects of interaction between SLC12A3 polymorphism, salt-sensitive gene, and sodium intake on risk of child obesity (소금민감성 SLC12A3 유전자 다형성에 따른 나트륨섭취가 소아비만에 미치는 영향)

  • Jung, Joohyun;Lee, Myoungsook
    • Journal of Nutrition and Health
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    • v.50 no.1
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    • pp.32-40
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    • 2017
  • Purpose: Obesogenic environments in children, in particular excessive intake of sodium, generate hypertension, which is a major risk factor for chronic diseases. Methods: In all, 725 children, 379 boys and 373 girls, aged 8~9 years were recruited from seven elementary schools in Kuro-ku, Seoul. To evaluate whether or not obesity risk was modulated by salt-sensitive genes, Solute Carrier Familiy 12 member 3 (SLC12A3) was used as the target. After children were assigned into obese (BMI > 85 percentile) or non-obese groups, anthropometry, blood biochemistry, and dietary intakes were measured according to the genotypes GG (wild) or GA+AA (hetero+mutant). Results: Without gender differences, high TG and low HDLc were detected in the obese group compared to the non-obese group. Regardless of obesity, weight gain and blood pressure (BP) increased in the SLC12A3 GA+AA genotype rather than in the GG type. HDLc was associated with obesity risk without genotype difference. Odd ratios for risk of obesity were 15.57 (95% CI 2.192~110.654), 22.84 (95% CI 1.565~333.469), and 9.32 (95%CI 1.262~68.817) in boys and girls with GA+AA genotypes as sodium intake increased above 4,000 mg/day. Dietary calcium, sodium, folate, and vit C were associated with obesity risk according to gender or genotype differences. Since high folate intake reduced obesity risk in only boys with GG type. Risk for overweight and obesity increased in boys with GA+AA genotypes and dietary habits with high sodium and cholesterol and low folate. Conclusion: The A allele of SLC12A3 rs11643718 was sensitive to development of obesity in children as sodium intake increased.

Effects of Hwangryunhaedok-tang plus Yukmijihwang-tang add Chogudeung on Blood Pressure and Renal Function in Spontaneously Hypertensive Rats (황연해독탕 합 육미지황탕 가 조구등이 자발적 고혈압 백서의 혈압 및 현장 기능에 미치는 영향)

  • Sohn Eun Jin;Kang Dae Gill;Lee An Sook;Kim Bok Hae;Lee Ho Sub
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.2
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    • pp.359-364
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    • 2002
  • The present study examined the effects of water extract of Hwangruynhaedoktang plus Yukmijihwangtang add Chogudeung (HYC) on the blood pressure and renal function in spontaneously hypertensive rats (SHR). The HYC water extract blocked increase of systolic blood pressure (SBP) in SHR. The urinary volume (UV), sodium (UNaV), potassium (UkV), and chloride (UclV) excretions were significantly increased in SHR administered with high dose of water extract of HYC, but urinary osmolality was not changed. The creatinine clearance (Ccr), which is index of glomerular filtration rate (GFR), was increased by administration of HYC, while solute-free water reabsorption (TcH2O) was not changed. Taken together, these results suggest that the depressor effects of HYC, at least in part, caused by diuretic effect due to increase of glomerular filtration rate.

An Overview of the Applicability of Oryung-san as an Antihypertensive Agent (오령산의 고혈압 치료약물 가능성에 대한 개관)

  • Jeong, Min-jeong;Kang, Ki-wan;Kang, Ja-yeon;Yoon, Jee-hyun;Choi, Yoo-min;Kim, Hong-jun;Sun, Seung-ho;Jang, In-soo
    • The Journal of Internal Korean Medicine
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    • v.38 no.4
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    • pp.443-454
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    • 2017
  • Objectives: This study assessed the application of Oryung-san (Wuling-san or Gorei-san), a common diuretic in traditional medicine, as an antihypertensive agent. Methods: Experimental studies of the pharmacological properties of Oryung-san, including diuretic action and lowering effects on blood pressure, and toxicology and clinical trials were reviewed. Results: In pharmacology, various, relatively safe diuretics are used to lower blood pressure and are the oldest and most studied antihypertensive agents. Despite many new drug approvals, antihypertensive diuretics are frequently used in Korea and Japan where high levels of sodium uptake are common. Oryung-san has been demonstrated to have diuretic, antihypertensive, and nephroprotective effects. Conclusions: Oryung-san might be effective for lowering blood pressure based on the results of this literature review. Further evaluations and large-scale clinical trials of Oryung-san to treat primary hypertension are warranted.

A Study on Visual Clarity According to Color Temperature and Color Rendering of Light Sources (각종 광원의 색온도, 연색성과 밝은 느낌에 대한 실험적 연구)

  • 이진우;지철근;조경애
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.17 no.6
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    • pp.1-6
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    • 2003
  • We studied visual clarity according to the difference of color temperature and color rendering by using black and white printed paper and four sheets of colored paper under different kinds of lamps and same kind lamps. The results show visual clarity is proportioned to average color rendering index approximately except incandescent lamps and to color temperature under incandescent lamps, fluorescent lamps, high pressure sodium lamps, metal halide lamps and electrode less discharge lamps.

Genenal Pharmacological Action of Ginseng Preparation (인삼제제(人蔘製劑)의 일반약리(一般藥理)에 관(關)한 연구(硏究))

  • Shin, Sang-Chul;Han, Byung-Hoon
    • Journal of Pharmaceutical Investigation
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    • v.14 no.2
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    • pp.86-91
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    • 1984
  • A ginseng preparation (GP) consisting of ginseng ex., lycium fructus ex., four kinds of vitamines and caffein was evaluated for acute toxicity and general pharmacology. Average lethal doses $(LD_{50})$ of GP in male mice were 2,988mg/kg (i.p.) and more than 3g/kg (p.o.). In dosage of 300 and 900mg/kg (p.o.) showed no analgesic activity in both tests of the writhing method induced by acetic acid and of tail pressure method and no effect on the pentetrazole-induced convulsion. However, it appeared to have a hypothermic action only in dose of 900mg/kg. The duration of hypnosis induced by hexobarbital sodium in mice was shortened by GP, being probably due to caffein. GP Produced no marked contraction of isolated ileum and uterus in high concentrations of up to $1{\pm}10^{-3}g/ml$. These results suggested that GP did not show any considerable central nervous depressant activity and exhibited very weak actue toxicity in mice.

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THE NIGHT SKY SPECTRUM OF MOUNT BOHYUN

  • SHEEN YUN-KYEONG;BYUN YONG-IK
    • Journal of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.87-90
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    • 2004
  • Spectrophotometry of the night sky over Mount Bohyun is presented for the nearly entire visible wavelengths of $3600{\~}$8600{\AA}$. The data was obtained under moonless clear sky in February 2004 with the 1.8-m telescope and the long slit spectrograph. The sky spectrum shows a number of strong emission lines originated from light pollution, especially due to high pressure sodium lamps. When compared to the night sky of Kitt Peak, our sky continuum is 1 to 2 magnitude brighter at all wavelengths, the worst being around the broad emission region near 6000${\AA}$. The night sky spectrum presented here with almost complete line identifications is a useful reference for arc-independent wavelength calibrations to check the gravity flexure of the spectrograph and the wavelength shift between FeNeArHe arc frames and science frames.

A Study on the Simplification of the Calculation of the Radiation Energy of a High Pressure Sodium Lamp (고압나트륨 램프의 방사에너지 계산 간략화에 관한 연구)

  • 치철근;김창섭
    • The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.5 no.1
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    • pp.40-45
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    • 1991
  • This paper proposes a simplifying model for the calculation of the radiant flux and radiation energy in an RD (Radiation Dominated) arcplasma. Defects of the previous models are that the radiant flux and radition energy must be numerically solved by the three dimensional integration, and these calculations demand enormous computing time. Thses attribute to the global properties of radiation transfer. This paper suggests a simple calculation technique of radiation characteristics by considerig the relation between the plasma states and the radiation transfer process and by the systematic tabulation of the relation.

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A life test of metal halide and high pressure sodium lamp according to voltage variation (전원전압 변동에 따른 메탈핼라이드램프와 고압나트륨램프의 수명시험)

  • Chee, Chol-Kon;Yi, Chin-Woo;Cho, Ho-Yon;Ahn, Jae-Hyuk
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2006.05a
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    • pp.228-229
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    • 2006
  • 본 논문에서는 250W 메탈핼라이드램프와 250W 고압나트륨램프에 대하여 전원전압 변동에 따른 수명측정시험을 수행하였다. 시험 전압은 220V와 220V의 80%인 176V 두 가지 전압을 사용하였다. 시험 방법은 100시간 에이징 후, 일주일마다 광속을 측정하였다. 전원전압을 변경하여 연속점등시 조도측정시험 결과는 메탈핼라이드램프의 경우 정격전압의 80%에서는 정격전압의 경우보다 초기광속의 70%에 도달하는 시간이 약 30% 단축되는 것으로 조사되었다. 그러나 고압나트륨램프의 경우는 전압변동과 수명과의 관계를 파악할 수 없었다.

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CFD investigation of a JAEA 7-pin fuel assembly experiment with local blockage for SFR

  • Jeong, Jae-Ho;Song, Min-Seop
    • Nuclear Engineering and Technology
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    • v.53 no.10
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    • pp.3207-3216
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    • 2021
  • Three-dimensional structures of a vortical flow field and heat transfer characteristics in a partially blocked 7-pin fuel assembly mock-up of sodium-cooled fast reactor have been investigated through a numerical analysis using a commercial computational fluid dynamics code, ANSYS CFX. The simulation with the SST turbulence model agrees well with the experimental data of outlet and cladding wall temperatures. From the analysis on the limiting streamline at the wall, multi-scale vortexes developed in axial direction were found around the blockage. The vortex core has a high cladding wall temperature, and the attachment line has a low cladding wall temperature. The small-scale vortex structures significantly enhance the convective heat transfer because it increases the turbulent mixing and the turbulence kinetic energy. The large-scale vortex structures supply thermal energy near the heated cladding wall surface. It is expected that control of the vortex structures in the fuel assembly plays a significant role in the convective heat transfer enhancement. Furthermore, the blockage plate and grid spacer increase the pressure drop to about 36% compared to the bare case.

ERRATUM : Effect of Stem Number on Growth, Fruit Quality, and Yield of Sweet Peppers Grown in Greenhouses under Supplemental Lighting with High Pressure Sodium Lamps in Winter (ERRATUM : 겨울철 고압나트륨등 보광 하에서 온실재배 파프리카의 줄기 유인 수가 생육, 과실 품질 및 생산량에 미치는 영향)